Ischemia-reperfusion Injury
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2026-03-25Clinical Trial Update: Non-invasive Remote Ischemic PreConditioning (RIPC) in Free Flaps for Breast Reconstruction [NA]
Completed clinical trial evaluating non-invasive remote ischemic preconditioning to protect free flap breast reconstruction from ischemia-re…
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CLINICAL_TRIALS trial_result · 2026-03-17Clinical Trial Update: Vitamin B6 on Exercise Pressor Reflex on Leg Ischemia-reperfusion [EARLY_Phase 1]
An early-phase clinical trial is evaluating the effect of Vitamin B6 (pyridoxine) on the exercise pressor reflex during leg ischemia–reperfu…
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CLINICAL_TRIALS trial_result · 2026-02-06Clinical Trial Update: Investigation of the Protective Effect of Alpha Lipoic Acid on Ischemic Reperfusion Damage in Ischemic Priapism in Rats [NA]
Preclinical study in rats examining whether alpha-lipoic acid can protect against ischemia-reperfusion damage in priapism.
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CLINICAL_TRIALS trial_result · 2025-04-24Clinical Trial Update: The Effect of Prolonged ischemıa and anesthetıc Agents on Oxidative Stress
Duzce University conducted a clinical trial to assess the effect of prolonged ischemia and anesthetic agents on oxidative stress, and the st…
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CLINICAL_TRIALS trial_result · 2025-04-17Clinical Trial Update: A Study to Evaluate the Safety and Pharmacokinetics of BX-001N in Healthy Participants [Phase 1]
Phase 1 trial update showing completion of a safety and pharmacokinetics study of BX-001N in healthy participants, with the ischemia-reperfu…
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CLINICAL_TRIALS trial_result · 2025-03-12Clinical Trial Update: NAD+ Augmentation in Cardiac Surgery Associated Myocardial Injury Trial [Phase 2]
Phase 2 clinical trial evaluating NAD+ augmentation for ischemia-reperfusion injury with associated myocardial and kidney injuries is curren…
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CLINICAL_TRIALS trial_result · 2025-02-21Clinical Trial Update: Hypertonic Lactate After Cardiac Arrest [Phase 2]
A Phase 2 clinical trial evaluating hypertonic lactate after cardiac arrest is currently recruiting to assess its effects on ischemia-reperf…
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CLINICAL_TRIALS trial_result · 2024-12-11Clinical Trial Update: Repertaxin in Prevention of Primary Graft Dysfunction After Lung Transplantation [Phase 2]
Phase 2 trial evaluating Repertaxin to prevent primary graft dysfunction after lung transplantation has completed and results posted.
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CLINICAL_TRIALS trial_result · 2024-08-14Clinical Trial Update: Intracoronary Administration of Glucocorticoids as a Treatment Method for No-Glucocorticoid Treatment for No-Reflow in STEMI [Phase 2]
Phase 2 trial evaluating intracoronary glucocorticoids for no-reflow in STEMI has completed.
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CLINICAL_TRIALS trial_result · 2024-08-13Clinical Trial Update: Effects of Anesthesia Technique on Endothelial Function [NA]
A clinical trial is investigating how anesthesia technique affects endothelial function in conditions such as endothelial dysfunction and is…
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CLINICAL_TRIALS trial_result · 2024-06-04Clinical Trial Update: FIH Phase I/IIa Trial Evaluating Safety of TUM012 to Minimize Ischemic Reperfusion Injury in Kidney Transplantation [Phase 1, Phase 2]
An early-phase (Phase I/IIa) clinical trial evaluating the safety of TUM012 to minimize ischemia-reperfusion injury in kidney transplantatio…
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CLINICAL_TRIALS trial_result · 2024-03-21Clinical Trial Update: Effect of Dexmedetomidine Preconditioning on Myocardial Ischemia-reperfusion Injury in Patients Undergoing Open Heart Surgery With Cardiopulmonary Bypass [Phase 4]
Phase 4 clinical trial evaluating dexmedetomidine preconditioning for protection against myocardial ischemia-reperfusion injury in open hear…
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CLINICAL_TRIALS trial_result · 2022-11-25Clinical Trial Update: Effectiveness of IV Vitamin C in Reducing Oxidative Stress Associated With Free Flap Surgery [Phase 3]
Phase 3 trial evaluating the effectiveness of intravenous vitamin C to reduce oxidative stress associated with free flap surgery; status cur…
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CLINICAL_TRIALS trial_result · 2021-05-28Clinical Trial Update: Effect of Nitric Oxide (NO) on Ischemic/Reperfusion Injury During Extended Donor Criteria (EDC) Liver Transplantation [NA]
A terminated clinical trial investigated the effect of nitric oxide on ischemia/reperfusion injury during extended donor criteria liver tran…
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CLINICAL_TRIALS trial_result · 2020-08-11Clinical Trial Update: Effects of Intravenous Bendavia™ on Reperfusion Injury in Patients Undergoing Angioplasty of the Renal Artery [Phase 1, Phase 2]
Phase 1/2 trial evaluating intravenous Bendavia for reperfusion injury during renal artery angioplasty; the study was terminated with result…
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CLINICAL_TRIALS trial_result · 2020-04-14Clinical Trial Update: Reparixin in Prevention of Delayed Graft Function After Kidney Transplantation [Phase 2]
Phase 2 clinical trial update on reparixin to prevent delayed graft function after kidney transplantation following ischemia-reperfusion inj…
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CLINICAL_TRIALS trial_result · 2020-04-03Clinical Trial Update: Efficacy of Nitric Oxide Administration in Attenuating Ischemia/Reperfusion Injury During Neonatal Cardiopulmonary Bypass [NA]
This completed clinical trial evaluated whether administering inhaled nitric oxide during neonatal cardiopulmonary bypass reduces ischemia/r…
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CLINICAL_TRIALS trial_result · 2019-08-19Clinical Trial Update: The Effect of Remote Ischemic Preconditioning in Living Donor Hepatectomy [NA]
Clinical trial update on remote ischemic preconditioning in living donor hepatectomy; study completed and results posted.
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CLINICAL_TRIALS trial_result · 2019-05-22Clinical Trial Update: Clinical Study of Cardiomyopeptidin on Postoperative Ischemia-reperfusion Injury in Patients With Primary PCI [Phase 4]
Phase 4 clinical trial update for Cardiomyopeptidin in patients undergoing primary PCI, focusing on myocardial survival area and left ventri…
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CLINICAL_TRIALS trial_result · 2019-02-21Clinical Trial Update: Desflurane Preconditioning in Hepatectomies [NA]
A completed clinical trial update examining desflurane preconditioning in liver resection to mitigate ischemia-reperfusion injury.
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CLINICAL_TRIALS trial_result · 2019-01-28Clinical Trial Update: The Del Nido Versus Cold Blood Cardioplegia in Aortic Valve Replacement [NA]
Completed clinical trial comparing Del Nido versus cold blood cardioplegia in aortic valve replacement; the study status indicates completio…
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CLINICAL_TRIALS trial_result · 2018-11-19Clinical Trial Update: The Effect of Pregabalin Given Preoperatively on the Tourniquet Induced Ischemia-reperfusion [Phase 4]
Phase 4 clinical trial evaluating the effect of pregabalin given preoperatively on tourniquet-induced ischemia-reperfusion injury has comple…
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CLINICAL_TRIALS trial_result · 2018-06-25Clinical Trial Update: C1INH Inhibitor Preoperative and Post Kidney Transplant to Prevent DGF & IRI [Phase 1, Phase 2]
Phase 1/2 trial evaluating C1 esterase inhibitor given before and after kidney transplant to prevent Delayed graft function and ischemia-rep…
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CLINICAL_TRIALS trial_result · 2018-06-13Clinical Trial Update: Effect of Dexmedetomidine on Ischemia-Reperfusion Injury in Lower Extremity Operations [NA]
A completed clinical trial evaluating the effect of dexmedetomidine on ischemia-reperfusion injury in patients undergoing lower-extremity ar…
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CLINICAL_TRIALS trial_result · 2018-05-09Clinical Trial Update: Dexmedetomidine Effect on Mitochondrial Function [Phase 4]
Phase 4 clinical trial evaluating the effect of dexmedetomidine on mitochondrial function, sponsored by The Hospital for Sick Children; the …