Ischemia-reperfusion Injury
📧 Sign up to get email alerts when something new happens for Ischemia-reperfusion Injury.
Sign up freeTop drugs studied for this disease
-
CLINICAL_TRIALS trial_result · 2018-05-03Clinical Trial Update: Microcirculation and Anesthesia in Vascular Surgery
Completed clinical trial evaluating microcirculation and anesthesia in vascular surgery, with focus on ischemia-reperfusion injury and aorti…
-
CLINICAL_TRIALS trial_result · 2017-12-15Clinical Trial Update: Protection of the Heart With Doxycycline During Coronary Artery Bypass Grafting [Phase 2]
Phase 2 trial updating the protection of the heart with doxycycline during coronary artery bypass grafting.
-
CLINICAL_TRIALS trial_result · 2017-12-11Clinical Trial Update: Determination of the Role of Oxygen in Suspected Acute Myocardial Infarction by Biomarkers [Phase 3]
Phase 3 trial update evaluating the role of oxygen in suspected acute myocardial infarction using biomarkers; the study has completed.
-
CLINICAL_TRIALS trial_result · 2017-12-11Clinical Trial Update: Effects of Oxygen Treatment on Mechanisms Involved in Ischemia-reperfusion Injury: A Pilot Study in Healthy Volunteers [Phase 1]
Phase 1 pilot study in healthy volunteers assessing how oxygen treatment influences mechanisms involved in ischemia-reperfusion injury.
-
CLINICAL_TRIALS trial_result · 2017-05-12Clinical Trial Update: Ischemia Reperfusion: Prostaglandins and Antioxidants [NA]
A University of Essex-sponsored trial investigating prostaglandins and antioxidants for ischemia-reperfusion injury has completed.
- Want full summaries, importance scores, and drug timelines? Upgrade to Plus or Pro.
-
CLINICAL_TRIALS trial_result · 2017-05-10Clinical Trial Update: Limitation of Ischemic Injury of a Kidney Stored in Machine Perfusion in Hypothermia - Evaluation of the Impact on Kidney Allograft Function [Phase 2]
Phase 2 trial evaluating whether hypothermic machine perfusion can limit ischemic injury to a transplanted kidney and improve allograft func…
-
CLINICAL_TRIALS trial_result · 2017-03-23Clinical Trial Update: TOP-Study (Tacrolimus Organ Perfusion): Treatment of Ischemia Reperfusion Injury in Marginal Organs With an ex Vivo Tacrolimus Perfusion [Phase 2, Phase 3]
The TOP-Study evaluated ex vivo tacrolimus perfusion to treat ischemia-reperfusion injury in marginal liver grafts (Phase 2/3). The trial st…
-
CLINICAL_TRIALS trial_result · 2017-02-23Clinical Trial Update: Evaluation of Preimplantation Portal Vein and Hepatic Artery Flushing With Tacrolimus [NA]
A completed clinical trial evaluated tacrolimus flushing for use during liver transplantation to mitigate ischemia-reperfusion injury and ea…
-
CLINICAL_TRIALS trial_result · 2017-01-27Clinical Trial Update: Effects of Dexmedetomidine on the Liver Injury After Hepatectomy [Phase 4]
Phase 4 trial evaluating whether dexmedetomidine reduces liver injury after hepatectomy in the context of ischemia-reperfusion, with the stu…
-
CLINICAL_TRIALS trial_result · 2017-01-04Clinical Trial Update: The Effect of Melatonin on Ischemia-reperfusion Injury Following Acute Myocardial Infarction [Phase 2]
Phase 2 trial examining whether melatonin can reduce ischemia-reperfusion injury after acute myocardial infarction has completed.
-
CLINICAL_TRIALS trial_result · 2016-10-21Clinical Trial Update: Efficacy Evaluation of Normothermic Perfusion Machine Preservation in Liver Transplant Using Very Old Donors [NA]
This clinical trial update describes an efficacy evaluation of normothermic perfusion machine preservation in liver transplantation using ve…
-
CLINICAL_TRIALS trial_result · 2016-09-09Clinical Trial Update: Inhaled Nitric Oxide in Prevention/Treatment of Ischemia-Reperfusion Lung Injury Related to Lung Transplantation [Phase 3]
A Phase 3 trial evaluating inhaled nitric oxide to prevent or treat ischemia-reperfusion lung injury in lung transplant patients was termina…
-
CLINICAL_TRIALS trial_result · 2016-04-07Clinical Trial Update: Sevoflurane Protective Effect on Ischemia-reperfusion Injury. Multicenter, Randomized Controlled Trial [NA]
A multicenter randomized controlled trial evaluated sevoflurane's protective effect on ischemia-reperfusion injury in microsurgical free fla…
-
CLINICAL_TRIALS trial_result · 2016-03-08Clinical Trial Update: Remote Ischemic Preconditioning in Elective Percutaneous Interventions [NA]
Clinical trial update indicates completion of a study evaluating remote ischemic preconditioning during elective percutaneous interventions …
-
CLINICAL_TRIALS trial_result · 2016-01-26Clinical Trial Update: Reperfusion-induced Self-antigen Excretion Following Major Liver Surgery
Clinical trial evaluating reperfusion-induced self-antigen excretion after major liver surgery has completed, in the setting of warm hepatic…
-
CLINICAL_TRIALS trial_result · 2016-01-12Clinical Trial Update: The Effect of EPLerenone on Ischemia Reperfusion Injury in Human myoCARDium [NA]
Clinical trial update indicating the completion of a study evaluating eplerenone for ischemia-reperfusion injury in human myocardium. Sponso…
-
CLINICAL_TRIALS trial_result · 2015-10-20Clinical Trial Update: Purge Vs no Purge in Living Donor Liver Transplantation Recipients [NA]
A completed clinical trial comparing Purge versus no Purge in living donor liver transplantation recipients, with results posted in 2015.
-
CLINICAL_TRIALS trial_result · 2015-05-27Clinical Trial Update: Induction of HO-1; a Therapeutic Approach to Reduce Ischaemia Reperfusion Injury (IRI) Following Deceased Donor Renal Transplantation [Phase 3]
Phase 3 trial update evaluating induction of heme oxygenase-1 to reduce ischemia-reperfusion injury and graft failure after deceased donor r…
-
CLINICAL_TRIALS trial_result · 2015-04-20Clinical Trial Update: Remote Ischaemic Preconditioning in Children Undergoing Cardiac Surgery [NA]
Clinical trial update for remote ischemic preconditioning in children undergoing cardiac surgery; study status is completed.
-
CLINICAL_TRIALS trial_result · 2015-01-21Clinical Trial Update: Remote Ischemic Postconditioning in Humans [NA]
This entry reports the completion and posting of results for a clinical trial evaluating remote ischemic postconditioning in patients with i…
-
CLINICAL_TRIALS trial_result · 2013-12-25Clinical Trial Update: The Effect of Remote Ischemic Postconditioning on Liver Graft and Renal Function in Patients Undergoing Living-related Liver Transplantation [NA]
This clinical trial evaluated whether remote ischemic postconditioning could improve liver graft and renal function after living-related liv…
-
CLINICAL_TRIALS trial_result · 2013-11-13Clinical Trial Update: Methylprednisolone N Acetylcysteine in Hepatic Resections [Phase 2]
Phase 2 trial evaluating methylprednisolone combined with N-acetylcysteine in hepatic resection was terminated.
-
CLINICAL_TRIALS trial_result · 2013-08-27Clinical Trial Update: Clinical and Genomic Responses to Open Heart Surgery [Phase 3]
Phase 3 clinical trial update reporting clinical and genomic responses to open heart surgery in ischemia-reperfusion injury.
-
CLINICAL_TRIALS trial_result · 2013-05-20Clinical Trial Update: The Metformin-FMD Trial [Phase 4]
Phase 4 Metformin-FMD trial has completed, investigating metformin's effects on ischemia-reperfusion injury and endothelial function.
-
CLINICAL_TRIALS trial_result · 2012-12-12Clinical Trial Update: Ischemia-reperfusion Injury Model on Healthy Volunteers and Measurement of Oxidative and Inflammatory Markers
This completed clinical trial in healthy volunteers modeled ischemia-reperfusion injury and measured oxidative and inflammatory markers.