Intrahepatic Cholangiocarcinoma

CLINICAL_TRIALS research · 2025-12-08

Clinical Trial Update: Study Assessing PET Imaging With Zirconium-labelled Girentuximab in Patients With HCC, ICC or NEN [NA]

A clinical trial is evaluating PET imaging with zirconium-labelled girentuximab in patients with hepatocellular carcinoma, intrahepatic chol…

CLINICAL_TRIALS trial_result · 2025-12-05

Clinical Trial Update: Treatment of Atezolizumab and Derazantinib in Patients With Advanced iCCA With FGFR2 Fusions/Rearrangements [Phase 2]

Phase 2 clinical trial update on combined atezolizumab and derazantinib for advanced intrahepatic cholangiocarcinoma with FGFR2 fusions.

CLINICAL_TRIALS research · 2025-12-05

Clinical Trial Update: Immunotherapy Combined With Y-90 SIRT Therapy in Advanced Stage Intrahepatic Biliary Tract Cancer (BTC) [Phase 2]

Phase 2 trial update shows ongoing immunotherapy combined with yttrium-90 SIRT therapy for intrahepatic cholangiocarcinoma; the study is cur…

CLINICAL_TRIALS research · 2025-12-04

Clinical Trial Update: Iparomlimab and Tuvonralimab Injection Combined With GemOX and Lenvatinib as Conversion Therapy for Initially Potentially Resectable Intrahepatic Cholangiocarcinoma and Gallbladder Cancer [Phase 2]

Phase 2 clinical trial evaluating the combination of iparomlimab and tuvonralimab with GemOX chemotherapy and lenvatinib as conversion thera…

CLINICAL_TRIALS research · 2025-11-28

Clinical Trial Update: A Trial of Apatinib and Adebrelimab in Combination With Chemotherapy in Patients With Unresectable ICC [Phase 2]

Phase 2 trial evaluating Apatinib and Adebrelimab with chemotherapy for unresectable intrahepatic cholangiocarcinoma is currently recruiting…

CLINICAL_TRIALS research · 2025-11-24

Clinical Trial Update: Phase II Clinical Study on the Efficacy and Safety of the Combination of Cadonilimab and Capecitabine in Adjuvant Therapy for Combined Hepatocellular Carcinoma and Intrahepatic Cholangiocarcinoma [Phase 2]

Phase II trial update for Cadonilimab plus Capecitabine as adjuvant therapy for combined hepatocellular-cholangiocarcinoma and intrahepatic …

CLINICAL_TRIALS research · 2025-11-18

Clinical Trial Update: Interventional AI-Human Collaboration for Liver Tumor Diagnosis [NA]

Completed interventional clinical trial examining an AI–human collaboration approach for diagnosing liver tumors. The study encompasses hepa…

CLINICAL_TRIALS research · 2025-11-10

Clinical Trial Update: Short Stitch Versus Traditional Suture for the Prevention of Incisional Hernia After Open Hepatectomy [Phase 2]

Phase 2 trial comparing short-stitch versus traditional suture to prevent incisional hernia after open hepatectomy (liver resection); curren…

CLINICAL_TRIALS trial_result · 2025-10-29

Clinical Trial Update: Sulfur Colloid SPECT/CT in Measuring Liver Function in Patients With Primary or Metastatic Liver Cancer Undergoing Radiation Therapy or Surgery [NA]

This trial update reports that the sulfur colloid SPECT/CT liver-function study in patients with hepatocellular carcinoma or intrahepatic ch…

CLINICAL_TRIALS trial_result · 2025-10-28

Clinical Trial Update: Contrast-Enhanced Ultrasound for the Prediction of Bile Duct Cancer Response to Radioembolization Treatment [Phase 2]

This Phase 2 trial evaluated Contrast-Enhanced Ultrasound as a predictor of response to radioembolization in intrahepatic cholangiocarcinoma…

CLINICAL_TRIALS trial_result · 2025-10-23

Clinical Trial Update: Pressure Enabled Delivery of SD-101 With Checkpoint Blockade for Primary Liver Tumors [Phase 1, Phase 2]

A Phase 1/2 trial evaluating pressure-enabled delivery of SD-101 in combination with checkpoint blockade for primary liver tumors has been t…

CLINICAL_TRIALS research · 2025-10-20

Clinical Trial Update: Radioembolization With Tremelimumab and Durvalumab for Locally Advanced Unresectable or Oligo-Metastatic Intrahepatic Cholangiocarcinoma [Phase 1]

This clinical trial update describes a Phase 1 study evaluating radioembolization combined with tremelimumab and durvalumab for locally adva…

CLINICAL_TRIALS trial_result · 2025-10-16

Clinical Trial Update: Taxoprexin® Treatment for Advanced Primary Cancers of the Liver, Gallbladder or Biliary Tract [Phase 2]

Phase 2 trial of Taxoprexin for advanced primary cancers of the liver, gallbladder, or biliary tract was terminated.

CLINICAL_TRIALS trial_result · 2025-10-09

Clinical Trial Update: Effects on Quality of Life With Zinc Supplementation in Patients With Gastrointestinal Cancer [NA]

This trial update describes the effects of zinc supplementation on quality of life in patients with gastrointestinal cancers. The study has …

CLINICAL_TRIALS research · 2025-10-08

Clinical Trial Update: Dosimetric Differences and Clinical Significance Analysis Between Body Gamma Knife and VMAT Radiotherapy for Primary Liver Cance

This clinical trial update assesses dosimetric differences between Body Gamma Knife and VMAT radiotherapy for primary liver cancers. It also…

CLINICAL_TRIALS research · 2025-10-06

Clinical Trial Update: A Randomized Trial of Surgical Decision-Making Guided by TDTP-RECIST [NA]

A randomized trial evaluating surgical decision-making guided by TDTP-RECIST for intrahepatic cholangiocarcinoma; the study is currently not…

CLINICAL_TRIALS trial_result · 2025-10-01

Clinical Trial Update: Nal-IRI With 5-fluorouracil (5-FU) and Leucovorin or Gemcitabine Plus Cisplatin in Advanced Biliary-tract Cancer [Phase 2]

This clinical trial update notes the completion of a phase 2 study evaluating nanoliposomal irinotecan (nal-IRI) with either 5-fluorouracil/…

CLINICAL_TRIALS research · 2025-09-16

Clinical Trial Update: A Cell-free DNA Methylation Blood-Based Test for Biliary Tract Cancers Screening

This clinical trial is evaluating a cell-free DNA methylation blood test for screening biliary tract cancers and is currently recruiting.

CLINICAL_TRIALS research · 2025-09-09

Clinical Trial Update: Preoperative Evaluation of Lymph Nodes of Cholangiocarcinoma (POELH-III)

This clinical trial POELH-III evaluates preoperative evaluation of lymph nodes in cholangiocarcinoma and is currently not yet recruiting.

CLINICAL_TRIALS trial_result · 2025-09-08

Clinical Trial Update: Evaluation the Palliative Effects of Colchicine on Primary Hepatic Malignant Tumors Unable to Receive Curative Treatment [Phase 2]

This Phase 2 trial evaluated colchicine for palliative treatment of primary hepatic malignant tumors in patients ineligible for curative tre…

CLINICAL_TRIALS research · 2025-09-04

Clinical Trial Update: Phase II-III Clinical Trial of PD1 Antibody (Toripalimab), Lenvatinib and GEMOX Neoadjuvant Treatment for Resectable Intrahepatic Cholangiocarcinoma With High-risk Recurrence Factors [Phase 2, Phase 3]

Updates on a Phase II-III neoadjuvant trial combining toripalimab, lenvatinib, and GEMOX for resectable intrahepatic cholangiocarcinoma; stu…

CLINICAL_TRIALS research · 2025-09-03

Clinical Trial Update: Iparomlimab and Tuvonralimab Combined With GC in Advanced ICC [Phase 2]

Phase 2 trial update of iparomlimab and tuvonralimab with gemcitabine/cisplatin for advanced intrahepatic cholangiocarcinoma, not yet recrui…

CLINICAL_TRIALS research · 2025-08-28

Clinical Trial Update: Cryoablation Combined With SHR-1701 Plus Famitinib in Patients With Advanced Intrahepatic Cholangiocarcinoma. [Phase 2]

Phase 2 trial evaluating cryoablation combined with SHR-1701 and famitinib for advanced intrahepatic cholangiocarcinoma; the study is not ye…

CLINICAL_TRIALS research · 2025-08-17

Clinical Trial Update: PErioperative CISGEM + Rilvegostomig in High-Risk Resectable Intra Hepatic CholangioCarcinoma [Phase 2]

A Phase 2 clinical trial evaluating preoperative CISGEM (cisplatin + gemcitabine) plus Rilvegostomig for high-risk resectable intrahepatic c…

CLINICAL_TRIALS trial_result · 2025-08-15

Clinical Trial Update: Gemcitabine, Cisplatin, and Nab-Paclitaxel Before Surgery in Patients With High-Risk Liver Bile Duct Cancer [Phase 2]

Phase 2 trial evaluating preoperative combination therapy with gemcitabine, cisplatin, and nab-paclitaxel for resectable cholangiocarcinoma,…

Top drugs studied for this disease