Intrahepatic Cholangiocarcinoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2026-07-01Clinical Trial Results: Hepatic Arterial Infusion (HAI) With Floxuridine (FUDR) and Dexamethasone (Dex) Combined With Systemic Gemcitabine and Oxaliplatin in Patients With Unresectable Intrahepatic Cholangiocarcinoma (ICC) [Phase 2]
Phase 2 trial evaluating hepatic arterial infusion with floxuridine and dexamethasone plus systemic gemcitabine and oxaliplatin in unresecta…
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CLINICAL_TRIALS trial_result · 2026-06-25Clinical Trial Results: mFOLFIRINOX Followed by Hepatic Arterial Infusion of Floxuridine and Dexamethasone With Systemic mFOLFIRI for Unresectable Liver-dominant Intrahepatic Cholangiocarcinoma [Phase 2]
Phase 2 clinical trial investigating mFOLFIRINOX followed by hepatic arterial infusion of floxuridine and dexamethasone with systemic mFOLFI…
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CLINICAL_TRIALS research · 2026-04-23Clinical Trial Update: A Study Evaluating the Efficacy and Safety of Multiple Immunotherapy-Based Treatment Combinations in Patients With Advanced Liver Cancers (Morpheus-Liver) [Phase 1, Phase 2]
Hoffmann-La Roche is conducting the MORPHEUS-Liver trial to evaluate the efficacy and safety of multiple immunotherapy-based treatment combi…
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CLINICAL_TRIALS research · 2026-04-22Clinical Trial Update: Y-90 With Durvalumab/Gem/Cis in Intrahepatic Cholangio [Phase 2]
Phase 2 clinical trial evaluating Yttrium-90 radioembolization combined with durvalumab, gemcitabine, and cisplatin for intrahepatic cholang…
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CLINICAL_TRIALS research · 2026-04-22Clinical Trial Update: Gemcitabine and Oxaliplatin Chemotherapy With or Without a Floxuridine and Dexamethasone Pump in People With Cholangiocarcinoma That Cannot Be Removed With Surgery [Phase 2]
A Phase 2 clinical trial evaluating gemcitabine and oxaliplatin chemotherapy with optional floxuridine/dexamethasone pump in patients with u…
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CLINICAL_TRIALS research · 2026-04-21Clinical Trial Update: Real-world Evaluation of the HistoSonics Edison System for Treatment of Liver Tumors Across Multidisciplinary Users (BOOMBOX: Master Study)
Clinical trial registry entry for real-world evaluation of HistoSonics' Edison System for treating liver tumors; study is currently recruiti…
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CLINICAL_TRIALS research · 2026-04-20Clinical Trial Update: Modified Immune Cells (Autologous Dendritic Cells) and a Vaccine (Prevnar) Combined With Immune Checkpoint Inhibition After High-Dose External Beam Radiation Therapy in Treating Patients With Unresectable Liver Cancer [Phase 1, Phase 2]
Phase 1/2 trial evaluating autologous dendritic cell therapy and Prevnar vaccine with immune checkpoint inhibition following high-dose exter…
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CLINICAL_TRIALS trial_result · 2026-04-17Clinical Trial Update: A Study of an FGFR2/3 Inhibitor (CGT4859) in Patients With Cholangiocarcinoma and Other Advanced Solid Tumors [Phase 1, Phase 2]
Phase 1/2 study of CGT4859, an FGFR2/3 inhibitor, for intrahepatic cholangiocarcinoma, cholangiocarcinoma, and other advanced solid tumors; …
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CLINICAL_TRIALS research · 2026-04-17Clinical Trial Update: Testing the Combination of the Anticancer Drug Durvalumab With Chemotherapy (Gemcitabine and Cisplatin) at Improving Outcomes for High-Risk Resectable Liver Cancer Before Surgery [Phase 2]
Phase 2 trial evaluating durvalumab with gemcitabine and cisplatin for high-risk resectable intrahepatic cholangiocarcinoma before surgery i…
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CLINICAL_TRIALS research · 2026-04-16Clinical Trial Update: A Single-Arm Study of Pembrolizumab With Gemcitabine and Cisplatin as Perioperative Therapy for Potentially Resectable Intrahepatic Cholangiocarcinoma [Phase 2]
A Phase 2, single-arm clinical trial evaluating pembrolizumab with gemcitabine and cisplatin as perioperative therapy for potentially resect…
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CLINICAL_TRIALS research · 2026-04-16Clinical Trial Update: Scout Dose of Resin Microspheres [NA]
This trial update notes that a Scout dose study of resin microspheres is recruiting for liver-directed radioembolization in hepatocellular c…
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CLINICAL_TRIALS research · 2026-04-15Clinical Trial Update: Surveys, Blood Testing, and Fibroscan in Screening for Liver Fibrosis and Liver Cirrhosis [NA]
This update describes a study that uses surveys, blood testing, and FibroScan to screen for liver fibrosis and liver cirrhosis in patients w…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Study of Chemotherapy, With or Without Binimetinib in Advanced Biliary Tract Cancers in 2nd Line Setting (A ComboMATCH Treatment Trial) [Phase 2]
Phase 2 clinical trial evaluating chemotherapy with or without binimetinib for advanced biliary tract cancers. The study is currently active…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: A Clinical Study to Evaluate the Efficacy and Safety of VG2025 in Intrahepatic Cholangiocarcinoma [Phase 2]
A Phase 2 clinical trial evaluating the efficacy and safety of VG2025 in intrahepatic cholangiocarcinoma is not yet recruiting.
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CLINICAL_TRIALS research · 2026-04-08Clinical Trial Update: A Phase II Study of Pemigatinib Plus Durvalumab in Previously Treated Advanced Intrahepatic Cholangiocarcinoma Patients With FGFR-2 Fusion or Rearrangement [Phase 2]
Phase II trial evaluating the combination of pemigatinib and durvalumab in previously treated advanced intrahepatic cholangiocarcinoma with …
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CLINICAL_TRIALS trial_result · 2026-04-07Clinical Trial Update: DEB-TACE Combined With Apatinib and PD-1 for the Treatment of Intrahepatic Cholangiocarcinoma [Phase 2]
Phase 2 study evaluating DEB-TACE combined with apatinib and a PD-1 antibody for intrahepatic cholangiocarcinoma has completed.
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CLINICAL_TRIALS research · 2026-04-06Clinical Trial Update: Liver Transplantation for Locally Advanced Intrahepatic Cholangiocarcinoma After SIRT and Chemotherapy [NA]
A clinical trial evaluating liver transplantation for locally advanced intrahepatic cholangiocarcinoma after selective internal radiation th…
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CLINICAL_TRIALS trial_result · 2026-04-03Clinical Trial Update: An Exosome-Based Liquid Biopsy for the Differential Diagnosis of Primary Liver Cancer
ClinicalTrials.gov entry for an exosome-based liquid biopsy to differentiate hepatocellular carcinoma from intrahepatic cholangiocarcinoma, …
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CLINICAL_TRIALS withdrawal · 2026-03-23Clinical Trial Update: Treat Primary and Metastatic Liver Tumors
Clinical trial NCT05240040 sponsored by Methodist Health System has been withdrawn; it concerns the treatment of intrahepatic cholangiocarci…
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CLINICAL_TRIALS research · 2026-03-20Clinical Trial Update: Liver Transplantation in Intrahepatic Cholangiocarcinoma
A clinical trial investigating liver transplantation for intrahepatic cholangiocarcinoma is currently recruiting.
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CLINICAL_TRIALS research · 2026-03-19Clinical Trial Update: A Study to Investigate ALE.P03 as Monotherapy in Adult Patients With Selected Advanced or Metastatic CLDN1+ Solid Tumors [Phase 1, Phase 2]
A Phase 1/2 clinical trial update shows ALE.P03 as monotherapy being studied in adults with selected advanced or metastatic CLDN1+ solid tum…
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CLINICAL_TRIALS trial_result · 2026-03-18Clinical Trial Update: A Study on Intratumoral Fibrosis and α-SMA Expression in Intrahepatic Cholangiocarcinoma
A completed clinical trial evaluating intratumoral fibrosis and alpha-SMA expression in intrahepatic cholangiocarcinoma.
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CLINICAL_TRIALS trial_result · 2026-03-13Clinical Trial Update: An Exosomal miRNA-based Liquid Biopsy for ICC Detection
The clinical trial NCT07225452 investigating an exosomal miRNA-based liquid biopsy for detecting intrahepatic cholangiocarcinoma has complet…
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CLINICAL_TRIALS trial_result · 2026-03-13Clinical Trial Update: Liquid Biopsy Using Exosomal miRNA Enables Risk Stratification of Potential Metastasis in Patients With Intrahepatic Cholangiocarcinoma.
This completed clinical trial evaluated using a liquid biopsy based on exosomal miRNA to stratify metastasis risk in intrahepatic cholangioc…
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CLINICAL_TRIALS research · 2026-03-13Clinical Trial Update: Detecting Lymph Node Metastasis in Intrahepatic Cholangiocarcinoma (LyMIC)
A completed clinical trial (LyMIC) studying detection of lymph node metastasis in intrahepatic cholangiocarcinoma. The trial was sponsored b…