Intrahepatic Cholangiocarcinoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-03-13Clinical Trial Update: Pressurized Intraperitoneal Aerosolized Nab-Paclitaxel in Combination With Gemcitabine and Cisplatin for the Treatment of Biliary Tract Cancer Patients With Peritoneal Metastases [Phase 1]
Phase 1 trial evaluating pressurized intraperitoneal aerosolized nab-paclitaxel in combination with gemcitabine and cisplatin for biliary tr…
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CLINICAL_TRIALS research · 2026-03-11Clinical Trial Update: HYPERION CCA: a Phase 2 Trial of Systemic Therapy With or Without Liver-directed Radiation Therapy for Patients With Advanced Intrahepatic Cholangiocarcinoma [Phase 2]
Phase 2 clinical trial (HYPERION CCA) evaluating systemic therapy with or without liver-directed radiation for advanced intrahepatic cholang…
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CLINICAL_TRIALS other · 2026-03-11Clinical Trial Update: Outpatient Versus Inpatient Care Pathway for Intra-arterial Treatment of Primary Liver Cancer (CHOC) [NA]
A clinical trial currently recruiting to compare outpatient versus inpatient care pathways for intra-arterial treatment of primary liver can…
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CLINICAL_TRIALS research · 2026-03-09Clinical Trial Update: Hepatic Arterial Infusion Chemotherapy (HAIC) Combined With Durvalumab and Lenvatinib in Patients With Locally Advanced or Metastatic Intrahepatic Cholangiocarcinoma: a Phase 2 Study(HAIC-quad Trial) [Phase 2]
A Phase 2 clinical trial (HAIC-quad) is evaluating hepatic arterial infusion chemotherapy combined with durvalumab and lenvatinib for locall…
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CLINICAL_TRIALS trial_result · 2026-03-05Clinical Trial Update: Hypofractionated Radiation Therapy and Bintrafusp Alfa for the Treatment of Advanced Intrahepatic Cholangiocarcinoma [Phase 1]
Phase 1 clinical trial evaluating hypofractionated radiation therapy in combination with Bintrafusp alfa for locally advanced or metastatic …
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CLINICAL_TRIALS trial_result · 2026-02-27Clinical Trial Update: REFOCUS: A First-in-Human Study of Highly Selective FGFR2 Inhibitor, RLY-4008, in Patients With ICC and Other Advanced Solid Tumors [Phase 1, Phase 2]
A first-in-human study of RLY-4008, a highly selective FGFR2 inhibitor, in intrahepatic cholangiocarcinoma and other advanced solid tumors h…
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CLINICAL_TRIALS research · 2026-02-25Clinical Trial Update: A Study of Liposomal Irinotecan Plus 5-FU/LV HAIC With Lenvatinib and a PD-1 Inhibitor in Advanced ICC [Phase 2]
Phase 2 trial evaluating liposomal irinotecan plus 5-FU/leucovorin hepatic arterial infusion with lenvatinib and a PD-1 inhibitor in advance…
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CLINICAL_TRIALS research · 2026-02-24Clinical Trial Update: PDS01ADC in Combination With Hepatic Artery Infusion Pump (HAIP) and Systemic Therapy for Subjects With Metastatic Colorectal Cancer, Intrahepatic Cholangiocarcinoma, or Metastatic Adrenocortical Carcinoma [Phase 2]
A Phase 2 clinical trial evaluating PDS01ADC with hepatic artery infusion pump and systemic therapy for metastatic colorectal cancer, intrah…
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CLINICAL_TRIALS research · 2026-02-09Clinical Trial Update: REGULUS: MRI-guided Adaptive SABR for Liver Cancers [Phase 2]
Stanford's REGULUS trial investigates MRI-guided adaptive SABR for liver cancers, including hepatocellular carcinoma and intrahepatic cholan…
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CLINICAL_TRIALS research · 2026-02-04Clinical Trial Update: Study of Safety/Feasibility of a Hybrid Model of Tertiary and Community Delivery of Hepatic Artery Infusion Chemotherapy [Phase 2]
This Phase 2 clinical trial evaluates the safety and feasibility of a hybrid tertiary- and community-delivery model for hepatic artery infus…
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CLINICAL_TRIALS research · 2026-02-02Clinical Trial Update: HAI-Floxuridine, or SIRT, Combined With Gemox For Patients With Intra-Hepatic Cholangiocarcinoma Not Amenable to Resection (TOMCAT) [Phase 2]
Phase 2 TOMCAT trial evaluating hepatic arterial infusion floxuridine (HAI-Floxuridine) or SIRT, combined with gemcitabine and oxaliplatin (…
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CLINICAL_TRIALS trial_result · 2026-01-28Clinical Trial Update: Perioperative Treatment of High-risk Resectable CCA With HAIC Plus A+T: Neobrave CCA [Phase 2]
This clinical trial update reports termination of a Phase 2 study evaluating perioperative hepatic arterial infusion chemotherapy with A+T (…
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CLINICAL_TRIALS research · 2026-01-23Clinical Trial Update: HAIC Combined With Immune Therapy for Advanced, Non-Resectable ICC [Phase 2]
A Phase 2 clinical trial is evaluating hepatic arterial infusion chemotherapy combined with immune therapy for advanced, non-resectable intr…
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CLINICAL_TRIALS research · 2026-01-23Clinical Trial Update: Percutaneous Cholangiopancreatoscopy Registry
Clinical trial registry entry for a Percutaneous Cholangiopancreatoscopy Registry; the study is listed as active but not recruiting.
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CLINICAL_TRIALS trial_result · 2026-01-21Clinical Trial Update: Oral Cryotherapy Plus Acupressure and Acupuncture Versus Oral Cryotherapy for Decreasing Chemotherapy-Induced Peripheral Neuropathy From Oxaliplatin-Based Chemotherapy in Patients With Gastrointestinal Cancer [Phase 2]
Phase 2 trial comparing oral cryotherapy with acupressure/acupuncture versus oral cryotherapy alone to prevent oxaliplatin-induced periphera…
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CLINICAL_TRIALS research · 2026-01-20Clinical Trial Update: FOLFOX-HAIC Combined With Donafenib and Pucotenlimab as First-Line Treatment for Unresectable Intrahepatic Cholangiocarcinoma [Phase 2]
Phase 2 clinical trial evaluating FOLFOX-HAIC combined with donafenib and pucotenlimab as first-line treatment for unresectable intrahepatic…
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CLINICAL_TRIALS research · 2026-01-13Clinical Trial Update: Prospective Evaluation of 68Ga-FAPI PET in Biliary Cancers
A prospective evaluation study assessing 68Ga-FAPI PET imaging for biliary cancers, currently recruiting.
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CLINICAL_TRIALS trial_result · 2026-01-09Clinical Trial Update: Efficacy and Safety of TT-00420 (Tinengotinib) Tablets Versus Chemotherapy in Patients With Advanced Intrahepatic Cholangiocarcinoma Harboring FGFR2 Fusions/Rearrangements or Mutations [Phase 3]
A Phase 3 trial evaluating Tinengotinib (TT-00420) versus chemotherapy in patients with advanced intrahepatic cholangiocarcinoma harboring F…
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CLINICAL_TRIALS trial_result · 2026-01-06Clinical Trial Update: HAIC Combined With Donafenib and Sintilimab for Unresectable ICC [Phase 2]
Phase 2 trial evaluating hepatic arterial infusion chemotherapy combined with donafenib and sintilimab for unresectable intrahepatic cholang…
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CLINICAL_TRIALS research · 2026-01-05Clinical Trial Update: Hepatic Arterial Infusion of Gemcitabine-oxaliplatin for Second-line Therapy in Non-metastatic Unresectable Intra-hepatic Cholangiocarcinoma [Phase 2]
Phase 2 study evaluating hepatic arterial infusion of gemcitabine and oxaliplatin as second-line therapy for non-resectable, non-metastatic …
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CLINICAL_TRIALS research · 2025-12-31Clinical Trial Update: HMPL-453 Tartrate in Advanced Intrahepatic Cholangiocarcinoma [Phase 2, Phase 3]
This clinical trial update indicates that the HMPL-453 tartrate study is being evaluated in advanced intrahepatic cholangiocarcinoma (Phase …
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CLINICAL_TRIALS trial_result · 2025-12-30Clinical Trial Update: HAIC Plus Systemic Chemotherapy, Lenvatinib and Toripalimab in Advanced ICC [Phase 2]
A Phase 2 trial evaluating hepatic arterial infusion chemotherapy plus systemic chemotherapy with lenvatinib and toripalimab in advanced int…
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CLINICAL_TRIALS trial_result · 2025-12-22Clinical Trial Update: NXP800 for the Treatment of Patients With Advanced or Metastatic Cholangiocarcinoma [Phase 1]
Phase 1 trial of NXP800 for advanced or metastatic cholangiocarcinoma has been terminated.
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CLINICAL_TRIALS research · 2025-12-22Clinical Trial Update: Contrast-enhanced MRI in Detecting Benign and Malignant Liver Lesions [NA]
Clinical trial update for contrast-enhanced MRI to detect benign and malignant liver lesions; the study is currently active but not recruiti…
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CLINICAL_TRIALS research · 2025-12-15Clinical Trial Update: Infusion System for Hepatic Cancer [NA]
An ongoing clinical trial is evaluating an infusion system for hepatic cancers, including colorectal cancer with liver metastases and intrah…