Hypertrophic Cardiomyopathy
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2022-11-28Clinical Trial Update: Sacubitril/Valsartan vs Lifestyle in Hypertrophic Cardiomyopathy [Phase 2]
A Phase 2 trial comparing sacubitril/valsartan to lifestyle intervention in patients with hypertrophic cardiomyopathy has completed.
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FDA approval · 2022-11-22FDA Approved: CAMZYOS — Supplemental Application (Myokardia, Inc.)
FDA approved a supplemental application for CAMZYOS (mavacamten) from Myokardia, Inc., expanding/ updating its labeling. The action pertains…
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CLINICAL_TRIALS trial_result · 2022-05-09Clinical Trial Update: Lifestyle and Pharmacological Interventions in Hypertrophic Cardiomyopathy [Phase 2, Phase 3]
A multi-phase trial investigating lifestyle and pharmacological interventions for hypertrophic cardiomyopathy has completed Phase 2 and Phas…
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FDA approval · 2022-04-28FDA Approved: CAMZYOS — Original Application (Myokardia, Inc.)
FDA approved CAMZYOS (mavacamten) from MyoKardia for adults with symptomatic obstructive hypertrophic cardiomyopathy, marking a new mechanis…
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CLINICAL_TRIALS trial_result · 2022-02-10Clinical Trial Update: Hypertrophic Cardiomyopathy Symptom Release by BX1514M [Phase 2]
Phase 2 clinical trial update for BX1514M in hypertrophic cardiomyopathy has completed.
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CLINICAL_TRIALS trial_result · 2021-11-02Clinical Trial Update: Hypertrophic Regression With N-Acetylcysteine in HCM [Phase 1]
Phase 1 trial update investigating N-Acetylcysteine for hypertrophic regression in hypertrophic cardiomyopathy; study completed with results…
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CLINICAL_TRIALS research · 2021-04-27Clinical Trial Update: Clinical and Therapeutic Implications of Fibrosis in Hypertrophic Cardiomyopathy [Phase 4]
Phase 4 clinical trial update exploring fibrosis in hypertrophic cardiomyopathy and its therapeutic implications.
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CLINICAL_TRIALS trial_result · 2021-03-29Clinical Trial Update: The Effect of Metoprolol in Patients With Hypertrophic Obstructive Cardiomyopathy. [Phase 2]
Phase 2 trial update examining the effect of metoprolol in patients with hypertrophic obstructive cardiomyopathy has completed.
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CLINICAL_TRIALS trial_result · 2021-03-11Clinical Trial Update: Role of Perhexiline in Hypertrophic Cardiomyopathy [Phase 2]
Phase 2 clinical trial exploring perhexiline for hypertrophic cardiomyopathy is ongoing or not yet updated.
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CLINICAL_TRIALS trial_result · 2021-03-11Clinical Trial Update: PRecIsion Medicine in CardiomyopathY
This trial update notes that a precision medicine study in hypertrophic cardiomyopathy has posted results, and the trial is currently not re…
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CLINICAL_TRIALS trial_result · 2021-01-11Clinical Trial Update: Valsartan for Attenuating Disease Evolution In Early Sarcomeric HCM [Phase 2]
Phase 2 trial evaluating valsartan for attenuation of disease evolution in early sarcomeric hypertrophic cardiomyopathy has been completed.
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CLINICAL_TRIALS trial_result · 2020-12-10Clinical Trial Update: Effects of Ranolazine on Coronary Microvascular Dysfunction in Patients With Hypertrophic Cardiomyopathy [Phase 2]
Phase 2 trial assessing the effects of ranolazine on coronary microvascular dysfunction in patients with hypertrophic cardiomyopathy (non-ob…
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CLINICAL_TRIALS trial_result · 2020-09-16Clinical Trial Update: Microvascular Dysfunction in Nonischemic Cardiomyopathy: Insights From CMR Assessment of Coronary Flow Reserve [Phase 4]
Phase 4 trial assessing microvascular dysfunction in nonischemic cardiomyopathy using CMR-derived coronary flow reserve; the study was termi…
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CLINICAL_TRIALS research · 2020-02-05Clinical Trial Update: A Phase 2 Open-label Pilot Study Evaluating MYK-461 in Subjects With Symptomatic Hypertrophic Cardiomyopathy and Left Ventricular Outflow Tract Obstruction [Phase 2]
A Phase 2 open-label pilot study evaluating MYK-461 in symptomatic hypertrophic cardiomyopathy with left ventricular outflow tract obstructi…
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CLINICAL_TRIALS trial_result · 2019-02-15Clinical Trial Update: Study of Exercise Training in Hypertrophic Cardiomyopathy [NA]
This clinical trial evaluated exercise training in people with hypertrophic cardiomyopathy. The study is completed and results were posted i…
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CLINICAL_TRIALS trial_result · 2019-02-05Clinical Trial Update: Assessment of Wall Thickness in Hypertrophic Cardiomyopathy
A clinical trial assessing wall thickness in hypertrophic cardiomyopathy has completed.
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CLINICAL_TRIALS trial_result · 2018-11-07Clinical Trial Update: A Pilot Project Exploring the Impact of Whole Genome Sequencing in Healthcare [NA]
A completed pilot trial investigated the impact of whole genome sequencing in healthcare, with results posted in 2018.
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CLINICAL_TRIALS research · 2018-06-28Clinical Trial Update: Risk Stratification in Children and Adolescents With Primary Cardiomyopathy
The update describes risk stratification efforts in pediatric patients with primary cardiomyopathy, including multiple cardiomyopathy subtyp…
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CLINICAL_TRIALS trial_result · 2018-06-27Clinical Trial Update: Extended Ambulatory Monitoring Improves Risk Stratification in Hypertrophic Cardiomyopathy
Clinical trial update indicates that extended ambulatory monitoring improves risk stratification in hypertrophic cardiomyopathy.
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CLINICAL_TRIALS research · 2018-05-09Clinical Trial Update: Evaluating the Effect of Spironolactone on Hypertrophic Cardiomyopathy [Phase 4]
A Phase 4 clinical trial evaluating spironolactone for hypertrophic cardiomyopathy with cardiac fibrosis; the study status is currently unkn…
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CLINICAL_TRIALS trial_result · 2018-05-01Clinical Trial Update: Genotype-Phenotype Associations in Pediatric Cardiomyopathy (PCM GENES)
A completed pediatric cardiomyopathy genotype-phenotype study (NCT01873963) sponsored by Wayne State University, examining genotype-phenotyp…
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CLINICAL_TRIALS trial_result · 2018-04-19Clinical Trial Update: An Integrative-"Omics" Study of Cardiomyopathy Patients for Diagnosis and Prognosis in China
A clinical trial in China is exploring an integrative 'omics' approach to diagnose and prognosticate various forms of cardiomyopathy, includ…
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CLINICAL_TRIALS research · 2018-03-27Clinical Trial Update: The Chinese Hypertrophic Cardiomyopathy Study(CHCS)
The Chinese Hypertrophic Cardiomyopathy Study (CHCS) is currently recruiting in China. It is sponsored by the China National Center for Card…
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CLINICAL_TRIALS trial_result · 2018-03-22Clinical Trial Update: Effect of Eleclazine (GS-6615) on Exercise Capacity in Subjects With Symptomatic Hypertrophic Cardiomyopathy [Phase 2, Phase 3]
Phase 2/3 trial evaluating Eleclazine (GS-6615) for improving exercise capacity in symptomatic hypertrophic cardiomyopathy was terminated wi…
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CLINICAL_TRIALS trial_result · 2018-02-05Clinical Trial Update: Assessment of Left Ventricular Torsion by Echocardiography Study
A completed clinical trial assessing left ventricular torsion by echocardiography in patients with Hypertrophic Cardiomyopathy; results post…