Hypertrophic Cardiomyopathy
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2024-11-13Clinical Trial Update: Natural History Study in Pediatric Patients With MYBPC3 Mutation-associated Cardiomyopathy
Pediatric natural history study investigating MYBPC3 mutation-associated cardiomyopathy, currently recruiting to characterize disease course…
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CLINICAL_TRIALS research · 2024-11-12Clinical Trial Update: Evaluation of Clinical Efficacy and Prognosis in Patients With Hypertrophic Obstructive Cardiomyopathy Through Hemodynamic Modeling Reconstructed by CT
A clinical trial evaluating CT-based hemodynamic modeling to assess clinical efficacy and prognosis in hypertrophic cardiomyopathy. The stud…
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CLINICAL_TRIALS trial_result · 2024-10-24Clinical Trial Update: A Noninterventional, Single-Center Feasibility Study to Evaluate Measures of Heart Failure Risk
A completed noninterventional, single-center feasibility study evaluating measures of heart failure risk.
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CLINICAL_TRIALS research · 2024-10-24Clinical Trial Update: A 10-Minute Cardiovascular Magnetic Resonance Protocol for Cardiac Disease
A McGill-led clinical trial update describes a 10-minute cardiovascular magnetic resonance protocol being studied for several cardiac condit…
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CLINICAL_TRIALS research · 2024-09-23Clinical Trial Update: Multimodal and Multidisciplinary Approach to Optimize Diagnostic, Prognostic, and Therapeutic Management of Patients with Non-ischemic Cardiomyopathies and Arrhythmogenic-inflammatory Phenotypes: a Multicenter, Observational, Retrospective and Prospective Registry Study.
A multicenter observational registry studying non-ischemic cardiomyopathies and arrhythmogenic-inflammatory phenotypes to optimize diagnosti…
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CLINICAL_TRIALS trial_result · 2024-09-19Clinical Trial Update: Viz HCM (ECG Assist) Utilization Workflow Pilot
A clinical trial update announcing the completion of Viz HCM (ECG Assist) Utilization Workflow Pilot for hypertrophic cardiomyopathy.
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CLINICAL_TRIALS trial_result · 2024-09-19Clinical Trial Update: An Observational Study of Subcutaneous Implantable Cardioverter Defibrillator in Patients with Hypertrophic Cardiomyopathy At High Risk of Sudden Cardiac Death
An observational study is evaluating the subcutaneous implantable cardioverter-defibrillator (S-ICD) in patients with hypertrophic cardiomyo…
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CLINICAL_TRIALS research · 2024-08-30Clinical Trial Update: Concomitant Hybrid Versus Catheter Ablation for Atrial Fibrillation With Hypertrophic Cardiomyopathy [NA]
A clinical trial in China is evaluating concomitant hybrid versus catheter ablation for atrial fibrillation in patients with hypertrophic ca…
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CLINICAL_TRIALS trial_result · 2024-08-29Clinical Trial Update: Study of Efficacy of Oral Sacubitril/Valsartan in Adult Patients With Non-obstructive Hypertrophic Cardiomyopathy [Phase 2]
A Phase 2 study evaluating the efficacy of sacubitril/valsartan in adults with non-obstructive hypertrophic cardiomyopathy has completed wit…
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CLINICAL_TRIALS research · 2024-08-15Clinical Trial Update: MEK Inhibitors for the Treatment of Hypertrophic Cardiomyopathy in Patients With RASopathies [Phase 2]
A Phase 2 clinical trial is evaluating MEK inhibitors for hypertrophic cardiomyopathy in patients with RASopathies, including Noonan syndrom…
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CLINICAL_TRIALS research · 2024-08-06Clinical Trial Update: Hypertrophic Cardiomyopathy Federated Learning Implementation Platform
This clinical trial update announces enrollment by invitation for a federated learning platform study in hypertrophic cardiomyopathy, sponso…
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CLINICAL_TRIALS research · 2024-08-01Clinical Trial Update: Prognostic Value of Angio-IMR in Hypertrophic Cardiomyopathy Patients
The document outlines an ongoing clinical trial evaluating whether Angio-IMR has prognostic value in patients with hypertrophic cardiomyopat…
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CLINICAL_TRIALS research · 2024-07-26Clinical Trial Update: Taiwan Registry of Hypertrophic Cardiomyopathy (THIC) Research Synopsis
A recruiting study under the Taiwan Registry of Hypertrophic Cardiomyopathy (THIC) led by Far Eastern Memorial Hospital to study hypertrophi…
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CLINICAL_TRIALS trial_result · 2024-07-25Clinical Trial Update: Study Evaluating the Pharmacokinetics of Mavacamten in Healthy Adult Chinese Subjects [Phase 1]
A Phase 1 pharmacokinetics study of mavacamten in healthy adult Chinese subjects has completed, with results posted in 2024. The sponsor lis…
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CLINICAL_TRIALS research · 2024-07-11Clinical Trial Update: Echocardiography-guided Percutaneous Septal Radiofrequency Ablation for Obstructive HCM After Alcohol Septal Ablation
A clinical trial update describes echocardiography-guided percutaneous septal radiofrequency ablation for obstructive hypertrophic cardiomyo…
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CLINICAL_TRIALS research · 2024-06-12Clinical Trial Update: Fabry Disease in High-risk Patients With Left Ventricular Hypertrophy: Prevalence and Implementation of a Clinical Score [NA]
This clinical trial update examines the prevalence of Fabry disease in high-risk patients with left ventricular hypertrophy and the implemen…
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CLINICAL_TRIALS trial_result · 2024-05-17Clinical Trial Update: Manganese-Enhanced Magnetic Resonance Imaging of the Myocardium
The document notes the completion of a clinical trial evaluating manganese-enhanced MRI of the myocardium in patients with ischemic, dilated…
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CLINICAL_TRIALS trial_result · 2024-05-06Clinical Trial Update: Use of SGLT2i in noHCM With HFpEF [Phase 4]
A Phase 4 clinical trial is recruiting to evaluate the use of SGLT2 inhibitors in non-obstructive hypertrophic cardiomyopathy with heart fai…
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CLINICAL_TRIALS research · 2024-05-06Clinical Trial Update: Assessment of Cardiac Function, Microvascular Function and Cardiac Perfusion in Different Disease Stages of Hypertrophic Cardiomyopathy
A clinical trial evaluating cardiac function, microvascular function, and cardiac perfusion across disease stages in hypertrophic cardiomyop…
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CLINICAL_TRIALS trial_result · 2024-05-02Clinical Trial Update: Anesthetic Management for TA-BSM in HOCM
This Clinical Trial Update reports the completion of a study evaluating anesthetic management for transapical beating-heart septal myectomy …
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FDA approval · 2024-04-30FDA Approved: CAMZYOS — Supplemental Application (Myokardia, Inc.)
The FDA approved a supplemental application for CAMZYOS (mavacamten) submitted by Myokardia, Inc., resulting in an approved modification to …
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FDA approval · 2023-12-19FDA Approved: CAMZYOS — Supplemental Application (Myokardia, Inc.)
FDA approved a supplemental application for Camzyos (mavacamten) from Myokardia, Inc., advancing regulatory action related to the drug.
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FDA approval · 2023-06-15FDA Approved: CAMZYOS — Supplemental Application (Myokardia, Inc.)
FDA approved a supplemental application for CAMZYOS (mavacamten) submitted by Myokardia, Inc. The action represents an additional approval r…
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CLINICAL_TRIALS trial_result · 2023-05-10Clinical Trial Update: Effect of Metoprolol in Post Alcohol Septal Ablation Patients With Hypertrophic Cardiomyopathy [Phase 4]
Phase 4 clinical trial update evaluating the effect of metoprolol in patients with hypertrophic cardiomyopathy after alcohol septal ablation…
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FDA approval · 2023-01-13FDA Approved: CAMZYOS — Supplemental Application (Myokardia, Inc.)
FDA approved a supplemental application for CAMZYOS (mavacamten) from Myokardia, Inc. The approval expands the drug’s indications for hypert…