Hypertrophic Cardiomyopathy
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2017-11-06Clinical Trial Update: Non-Invasive Evaluation of Myocardial Stiffness by Elastography in Pediatric Cardiology (Elasto-Pédiatrie) [NA]
The Elasto-Pédiatrie study, which evaluates non-invasive elastography for assessing myocardial stiffness in pediatric patients with dilated …
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CLINICAL_TRIALS trial_result · 2017-10-25Clinical Trial Update: Nitrite in Hypertrophic Cardiomyopathy (HCM) Study [Phase 1]
This document provides an update on a Phase 1 clinical trial evaluating nitrite therapy for hypertrophic cardiomyopathy. The study is sponso…
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CLINICAL_TRIALS trial_result · 2017-08-31Clinical Trial Update: Open-Label Study of Perhexiline in Patients With Hypertrophic Cardiomyopathy and Moderate to Severe Heart Failure [Phase 2]
An open-label Phase 2 study evaluating Perhexiline in patients with hypertrophic cardiomyopathy and moderate-to-severe heart failure was ter…
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CLINICAL_TRIALS research · 2017-08-25Clinical Trial Update: Insertable Cardiac Monitors in Hypertrophic Cardiomyopathy [NA]
Clinical trial update about the use of insertable cardiac monitors in patients with hypertrophic cardiomyopathy. The entry provides no phase…
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CLINICAL_TRIALS withdrawal · 2017-07-14Clinical Trial Update: Efficacy, Safety, and Tolerability of Perhexiline in Subjects With Hypertrophic Cardiomyopathy and Heart Failure [Phase 3]
A Phase 3 trial evaluating perhexiline for hypertrophic cardiomyopathy with heart failure has been withdrawn, with study data not advancing …
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CLINICAL_TRIALS trial_result · 2017-07-02Clinical Trial Update: Natural History and Results of Dual Chamber (DDD) Pacemaker Therapy of Children With Obstructive Hypertrophic Cardiomyop... [Phase 1]
This Phase 1 trial reports natural history and outcomes of dual-chamber DDD pacemaker therapy in children with obstructive hypertrophic card…
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CLINICAL_TRIALS trial_result · 2017-07-02Clinical Trial Update: Identification of Risk Factors for Arrhythmia in Children and Adolescents With Hypertrophic Cardiomyopathy
This update reports on a completed clinical trial investigating risk factors for arrhythmia in children and adolescents with hypertrophic ca…
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CLINICAL_TRIALS trial_result · 2017-05-31Clinical Trial Update: Deactivation of Implantable Cardioverter Defibrillator During Non-thoracic Surgical Procedures
This clinical trial update discusses strategies for deactivating implantable cardioverter-defibrillators (ICDs) during non-thoracic surgical…
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CLINICAL_TRIALS research · 2017-05-30Clinical Trial Update: Metabolomic Study of All-age Cardiomyopathy
An update on an ongoing metabolomic study investigating molecular profiles across multiple cardiomyopathy types, including dilated and hyper…
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CLINICAL_TRIALS research · 2017-05-16Clinical Trial Update: Presentations of Hypertrophic Cardiomyopathy on Myocardial Perfusion Imaging
Clinical trial update describing presentations of hypertrophic cardiomyopathy using myocardial perfusion imaging.
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CLINICAL_TRIALS trial_result · 2017-04-24Clinical Trial Update: Study to Develop a Non-invasive Marker for Monitoring Myocardial Fibrosis [Phase 2]
A Phase 2 study aiming to develop a non-invasive biomarker for monitoring myocardial fibrosis was terminated; the trial involved patients wi…
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CLINICAL_TRIALS trial_result · 2017-04-11Clinical Trial Update: Prognosis of Subjects With Unexplainable Precordial Deep T-wave Inversion Without Wall Thickness> 15mm
This clinical trial update reports on the prognosis of subjects with unexplainable precordial deep T-wave inversion and wall thickness not e…
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CLINICAL_TRIALS trial_result · 2017-01-18Clinical Trial Update: Ranolazine for the Treatment of Chest Pain in HCM Patients [Phase 4]
Phase 4 clinical trial evaluating ranolazine for chest pain in patients with hypertrophic cardiomyopathy, with results posted in 2017.
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CLINICAL_TRIALS trial_result · 2016-09-14Clinical Trial Update: Study Evaluating the Safety, Tolerability and Preliminary Pharmacokinetics and Pharmacodynamics of MYK-461 [Phase 1]
This Phase 1 study update reports safety, tolerability, and preliminary pharmacokinetic and pharmacodynamic data for mavacamten (MYK-461) in…
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CLINICAL_TRIALS research · 2016-06-17Clinical Trial Update: Molecular and Imaging Studies of Cardiovascular Health and Disease
Ongoing clinical trial update from the National Heart Centre Singapore reports molecular and imaging studies of cardiovascular health and di…
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CLINICAL_TRIALS research · 2016-03-25Clinical Trial Update: German Centre for Cardiovascular Research Cardiomyopathy Register
The document reports an update to the German Centre for Cardiovascular Research Cardiomyopathy Register, a clinical trial registry tracking …
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CLINICAL_TRIALS research · 2016-03-16Clinical Trial Update: Genetic Analysis of Familial Hypertrophic Cardiomyopathy
This update reports results from a completed clinical trial analyzing genetic factors in familial hypertrophic cardiomyopathy.
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CLINICAL_TRIALS other · 2016-02-23Clinical Trial Update: Using Magnetic Resonance Imaging to Evaluate Heart Vessel Function After Angioplasty or Stent Placement Procedures
A completed clinical trial update describes using magnetic resonance imaging to evaluate heart vessel function after angioplasty or stent pl…
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CLINICAL_TRIALS trial_result · 2015-09-03Clinical Trial Update: Study of Hypertrophic Cardiomyopathy Under Stress Conditions. Concordance Between Two Complementary Tests: Stress MRI and Exercice Stress Echocardiography [NA]
A clinical trial evaluating concordance between Stress MRI and Exercise Stress Echocardiography in patients with hypertrophic cardiomyopathy…
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CLINICAL_TRIALS research · 2015-08-13Clinical Trial Update: New Diagnostic Strategy in Hypertrophic Cardiomyopathy
This clinical trial update discusses a new diagnostic strategy being studied for hypertrophic cardiomyopathy.
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CLINICAL_TRIALS research · 2015-04-23Clinical Trial Update: Morbidity and Mortality in Patients With Hypertrophic Cardiomyopathy: a CALIBER Study
This clinical trial update describes the CALIBER study assessing morbidity and mortality in patients with hypertrophic cardiomyopathy.
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CLINICAL_TRIALS trial_result · 2015-04-07Clinical Trial Update: Treatment of Preclinical Hypertrophic Cardiomyopathy With Diltiazem [Phase 2, Phase 3]
Clinical trial update on diltiazem for preclinical hypertrophic cardiomyopathy in Phase 2/3, with results posted in 2015.
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CLINICAL_TRIALS trial_result · 2014-08-06Clinical Trial Update: Biventricular Pacing in Hypertrophic Cardiomyopathy After Aortic Valve Replacement [NA]
This clinical trial update indicates that a study evaluating biventricular pacing in hypertrophic cardiomyopathy after aortic valve replacem…
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CLINICAL_TRIALS trial_result · 2014-07-09Clinical Trial Update: Inhibition of the Renin Angiotensin System With Losartan in Patients With Hypertrophic Cardiomyopathy [Phase 2]
A Phase 2 trial evaluating losartan, a renin-angiotensin system inhibitor, for hypertrophic cardiomyopathy has completed.
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CLINICAL_TRIALS trial_result · 2014-03-26Clinical Trial Update: Neurohormonal Parameters in Hypertrophic Cardiomyopathies [NA]
This completed clinical trial assessed neurohormonal parameters across primary sarcomeric, obstructive, and non-obstructive hypertrophic car…