Hypercholesterolemia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2021-02-02Clinical Trial Update: Effectiveness of Treatment of Hypercholesterolemia With Rosuvastatin and Ezetimibe [Phase 4]
A phase 4 trial update assessing the effectiveness of rosuvastatin plus ezetimibe for hypercholesterolemia has been completed.
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CLINICAL_TRIALS trial_result · 2021-01-15Clinical Trial Update: Evaluating the Efficacy and Safety of Co-administrated Rosuvastatin/Ezetimibe and Telmisartan [Phase 3]
Phase 3 trial update assessing the combined Rosuvastatin/Ezetimibe with Telmisartan for hypercholesterolemia and hypertension has completed.
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CLINICAL_TRIALS trial_result · 2020-12-29Clinical Trial Update: An Efficacy and Safety Study of Alirocumab in Children and Adolescents With Homozygous Familial Hypercholesterolemia [Phase 3]
Phase 3 trial update evaluating alirocumab for efficacy and safety in children and adolescents with homozygous familial hypercholesterolemia…
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CLINICAL_TRIALS trial_result · 2020-12-22Clinical Trial Update: Assessment of the Long-Term Safety and Efficacy of Bempedoic Acid (CLEAR Harmony OLE) [Phase 3]
Phase 3 long-term safety and efficacy update of bempedoic acid (CLEAR Harmony OLE) completed; results posted in 2020.
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CLINICAL_TRIALS trial_result · 2020-12-17Clinical Trial Update: Evolocumab Plus Ezetimibe in Haemodialized Statin-intolerant Patients With Hypercholesterolemia [Phase 4]
A Phase 4 trial evaluating evolocumab plus ezetimibe in statin-intolerant patients with hypercholesterolemia undergoing hemodialysis.
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CLINICAL_TRIALS trial_result · 2020-12-09Clinical Trial Update: To Evaluate the Efficacy and Safety of Co-administrated Ezetimibe/Rosuvastatin and Telmisartan in Patients With Essential Hypertension and Primary Hypercholesterolemia [Phase 3]
A Phase 3 clinical trial evaluating the efficacy and safety of co-administered ezetimibe/rosuvastatin with telmisartan in patients with esse…
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CLINICAL_TRIALS trial_result · 2020-10-29Clinical Trial Update: Effect of Tredaptive on Serum Lipoproteins and Inflammatory Markers [Phase 4]
Phase 4 clinical trial update evaluating the effect of Tredaptive on serum lipoproteins and inflammatory markers in hypercholesterolemia.
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CLINICAL_TRIALS trial_result · 2020-08-12Clinical Trial Update: Clinical Trial to to Compare of the Efficacy and Safety of Lipilou® 20 mg and Lipilou® 10 mg [Phase 4]
A Phase 4 trial comparing the efficacy and safety of Lipilou 20 mg versus Lipilou 10 mg in hypercholesterolemia has been completed.
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CLINICAL_TRIALS trial_result · 2020-08-05Clinical Trial Update: Open-Label Extension of Study R727-CL-1003 (NCT01266876) to Evaluate the Long-Term Safety and Efficacy of Alirocumab (REGN727) in Participants With Heterozygous Familial Hypercholesterolemia (HeFH) [Phase 2]
Open-label extension study to assess long-term safety and efficacy of alirocumab in heterozygous familial hypercholesterolemia completed wit…
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CLINICAL_TRIALS trial_result · 2020-08-04Clinical Trial Update: Dapagliflozin and Cholesterol Metabolism in Type 2 Diabetes (DM2) [Phase 4]
Phase 4 trial update on dapagliflozin examining cholesterol metabolism in type 2 diabetes and hypercholesterolemia; study completed with res…
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CLINICAL_TRIALS trial_result · 2020-06-25Clinical Trial Update: A 12-Week, Phase 2 Study of Gemcabene in Hypercholesterolemia Patients on Stable Moderate and High-Intensity Statins [Phase 2]
Phase 2 trial update for gemcabene in hypercholesterolemia patients on stable statin therapy has completed, with results posted in 2020.
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CLINICAL_TRIALS trial_result · 2020-06-17Clinical Trial Update: A Study of Alirocumab in Participants With Autosomal Dominant Hypercholesterolemia (ADH) and Gain-of-Function Mutations (GOFm) of the Proprotein Convertase Subtilisin Kexin 9 (PCSK9) Gene or Loss-of-Function Mutations (LOFm) of the Apolipoprotein (Apo) B Gene [Phase 2]
Phase 2 study evaluating alirocumab in participants with autosomal dominant hypercholesterolemia due to GOFm PCSK9 or LOFm ApoB mutations; s…
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CLINICAL_TRIALS trial_result · 2020-05-29Clinical Trial Update: A Study of the Safety and Efficacy of Anacetrapib (MK-0859) Among Participants With Hypercholesterolemia When Added to Ongoing Statin Therapy (MK-0859-022) [Phase 3]
Phase 3 clinical trial evaluating safety and efficacy of anacetrapib (MK-0859) added to ongoing statin therapy in adults with hypercholester…
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CLINICAL_TRIALS trial_result · 2020-05-26Clinical Trial Update: Evolocumab Plus Ezetimibe in High Risk Haemodialized Statin Intolerant Patients [Phase 4]
Phase 4 clinical trial evaluating evolocumab plus ezetimibe in high-risk statin-intolerant patients undergoing hemodialysis.
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CLINICAL_TRIALS trial_result · 2020-04-27Clinical Trial Update: Evaluation of Long-Term Efficacy of Bempedoic Acid (ETC-1002) in Patients With Hyperlipidemia at High Cardiovascular Risk [Phase 3]
Phase 3 trial update assessing long-term efficacy of bempedoic acid in patients with hypercholesterolemia at high cardiovascular risk; resul…
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CLINICAL_TRIALS trial_result · 2020-04-24Clinical Trial Update: Investigating the Effects of Lipid-therapy Intensification With Alirocumab on Endothelial Function, Carotid Arteries, Lipoprotein Particle Subfractions, Inflammation and Post-prandial Lipemia [Phase 4]
Phase 4 trial investigating alirocumab intensification effects on endothelial function, carotid arteries, lipoprotein subfractions, inflamma…
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CLINICAL_TRIALS trial_result · 2020-04-20Clinical Trial Update: Evaluation of Long-Term Safety and Tolerability of ETC-1002 in High-Risk Patients With Hyperlipidemia and High CV Risk (CLEAR Harmony) [Phase 3]
Phase 3 long-term safety and tolerability evaluation of ETC-1002 in high-risk hyperlipidemia patients completed; results posted in 2020.
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CLINICAL_TRIALS trial_result · 2020-04-14Clinical Trial Update: Effect of an Atlantic Diet on Anthropometric Indices and Serum Lipid Profile [NA]
A completed clinical trial evaluating the effects of an Atlantic diet on anthropometric measures and lipid profile in individuals with cardi…
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CLINICAL_TRIALS trial_result · 2020-04-09Clinical Trial Update: Bempedoic Acid + Ezetimibe Fixed-Dose Combination (FDC) Study in Patients With Type 2 Diabetes and Elevated LDL-C [Phase 2]
Phase 2 trial evaluating a fixed-dose combination of bempedoic acid and ezetimibe in patients with type 2 diabetes and elevated LDL-C has co…
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CLINICAL_TRIALS trial_result · 2020-04-09Clinical Trial Update: Efficacy and Safety of Gemcabene in Patients With Low HDL-C and Either Normal or Elevated Triglycerides [Phase 2]
Phase 2 trial update assessing efficacy and safety of gemcabene in patients with low HDL-C and varying triglyceride levels; study completed.
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CLINICAL_TRIALS trial_result · 2020-04-09Clinical Trial Update: Efficacy and Safety of Gemcabene in Hypercholesterolemic Patients on Stable Statin Therapy [Phase 2]
Phase 2 trial update reporting efficacy and safety of gemcabene in hypercholesterolemia patients on stable statin therapy.
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CLINICAL_TRIALS trial_result · 2020-04-09Clinical Trial Update: Efficacy and Safety of Gemcabene in Hypercholesterolemic Patients as Monotherapy or in Combination With Atorvastatin [Phase 2]
Phase 2 trial update on gemcabene for hypercholesterolemia assessing monotherapy or combination with atorvastatin; completed.
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CLINICAL_TRIALS trial_result · 2020-04-03Clinical Trial Update: Evaluation of the Efficacy and Safety of Bempedoic Acid (ETC-1002) as Add-on to Ezetimibe Therapy in Patients With Elevated LDL-C (CLEAR Tranquility) [Phase 3]
Phase 3 trial update assessing bempedoic acid added to ezetimibe for lowering LDL-C in patients with hypercholesterolemia/atherosclerosis.
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CLINICAL_TRIALS trial_result · 2020-04-03Clinical Trial Update: Evaluation of the Efficacy and Safety of Bempedoic Acid (ETC-1002) in Patients With Hyperlipidemia and Statin Intolerant [Phase 3]
Phase 3 trial evaluating the efficacy and safety of bempedoic acid (ETC-1002) in hyperlipidemia patients intolerant to statins; study comple…
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CLINICAL_TRIALS trial_result · 2020-04-03Clinical Trial Update: Evaluation of the Efficacy and Safety of Bempedoic Acid (ETC-1002) 180mg, Ezetimibe 10mg, and Atorvastatin 20 mg Triplet Therapy in Patients With Elevated LDL-C [Phase 2]
Phase 2 trial evaluating a triplet therapy (bempedoic acid, ezetimibe, atorvastatin) for elevated LDL-C; results posted after completion.