Hypercholesterolemia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2023-11-18Clinical Trial Update: Multiple Ascending Dose Study of PCSK-9 Inhibitor (IBI306) in Chinese Patients With Hypercholesterolemia [Phase 2]
Phase 2 multiple ascending dose study of IBI306 (a PCSK-9 inhibitor) in Chinese patients with hypercholesterolemia has completed.
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CLINICAL_TRIALS trial_result · 2023-11-09Clinical Trial Update: Efficacy and Safety of Valsartan and the Combination of Valsartan and Simvastatin [Phase 3]
Phase 3 trial update evaluating efficacy and safety of valsartan alone and in combination with simvastatin for hypertension and hypercholest…
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CLINICAL_TRIALS trial_result · 2023-08-01Clinical Trial Update: Clinical Trial to Evaluate the Efficacy and Safety of DW1125 and DW1125A [Phase 3]
A Phase 3 clinical trial evaluating the efficacy and safety of DW1125 and DW1125A for hypercholesterolemia and dyslipidemia has been complet…
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CLINICAL_TRIALS trial_result · 2023-07-17Clinical Trial Update: Efficacy and Safety Study of Pitavastatin for Hypercholesterolemia [Phase 3]
Phase 3 trial update on pitavastatin for hypercholesterolemia with posted results.
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CLINICAL_TRIALS trial_result · 2023-05-25Clinical Trial Update: Supplements, Placebo, or Rosuvastatin Study [Phase 2]
Phase 2 clinical trial update for a rosuvastatin-related study in adults with hypercholesterolemia; results have been posted.
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CLINICAL_TRIALS trial_result · 2023-05-19Clinical Trial Update: Study of SHR-1209 in the Treatment of Hypercholesterolemia and Hyperlipidemia Ⅲ Stage [Phase 3]
Phase 3 clinical trial studying SHR-1209 for primary hypercholesterolemia and mixed hyperlipidemia has completed.
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CLINICAL_TRIALS trial_result · 2023-05-10Clinical Trial Update: Study of Efficacy and Safety of Inclisiran in Japanese Participants With High Cardiovascular Risk and Elevated LDL-C [Phase 2]
This Phase 2 study evaluated the efficacy and safety of Inclisiran in Japanese participants at high cardiovascular risk with elevated LDL-C.…
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CLINICAL_TRIALS trial_result · 2023-05-06Clinical Trial Update: An Efficacy and Safety Study of Alirocumab in Children and Adolescents With Heterozygous Familial Hypercholesterolemia [Phase 3]
Phase 3 trial update of alirocumab in children and adolescents with heterozygous familial hypercholesterolemia; study completed with results…
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CLINICAL_TRIALS trial_result · 2023-04-25Clinical Trial Update: SHR - 1209 Treatment Efficacy and Safety of the Patients With Hypercholesterolemia Ⅲ Period Clinical Research [Phase 3]
Phase 3 trial update assessing efficacy and safety of SHR-1209 for primary hypercholesterolemia; study completed.
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CLINICAL_TRIALS trial_result · 2023-04-04Clinical Trial Update: Evaluation of ETC-1002 in Participants With Hypercholesterolemia and Hypertension [Phase 2]
Phase 2 trial evaluating ETC-1002 in people with high cholesterol and high blood pressure has completed; results posted.
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CLINICAL_TRIALS trial_result · 2023-03-29Clinical Trial Update: Trial to Evaluate Efficacy and Safety of LIB003, Evolocumab and Alirocumab in High-risk CVD Patients [Phase 3]
Phase 3 trial evaluating LIB003 with Evolocumab and Alirocumab in high-risk cardiovascular disease patients has completed.
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CLINICAL_TRIALS trial_result · 2023-03-15Clinical Trial Update: The Efficacy and Safety of JS002 PFS and AI in Patients With Primary Hypercholesterolemia and Mixed Hyperlipidemia [Phase 3]
Phase 3 trial evaluating the efficacy and safety of JS002 for primary hypercholesterolemia and mixed hyperlipidemia has completed.
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CLINICAL_TRIALS trial_result · 2023-03-15Clinical Trial Update: Open-Label Study To Evaluate MN-001 on HDL & Triglyceride in NASH & NAFLD Subjects [Phase 2]
Phase 2 open-label trial evaluating MN-001 on HDL and triglycerides in subjects with NASH/NAFLD completed with results posted.
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CLINICAL_TRIALS trial_result · 2023-03-03Clinical Trial Update: A Multiple Ascending Dose Study of HTD1801 in Adults With Hypercholesterolemia [Phase 1, Phase 2]
Phase 1/2 multiple ascending dose study in adults with hypercholesterolemia has completed with results posted.
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CLINICAL_TRIALS trial_result · 2023-03-02Clinical Trial Update: A Study of PCSK9 Inhibitor AK102 in Patients With Hypercholesterolemia [Phase 2]
Phase 2 trial update for AK102, a PCSK9 inhibitor, in patients with hypercholesterolemia; study completed.
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CLINICAL_TRIALS trial_result · 2023-03-02Clinical Trial Update: A Long-term Study of AK102 in Patients With Hypercholesterolemia [Phase 2]
Phase 2 long-term study update of AK102 in patients with hypercholesterolemia has completed.
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CLINICAL_TRIALS trial_result · 2023-02-10Clinical Trial Update: Study of Evinacumab (REGN1500) in Participants With Persistent Hypercholesterolemia [Phase 2]
A Phase 2 clinical trial of evinacumab (REGN1500) in participants with persistent hypercholesterolemia has completed and posted results.
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CLINICAL_TRIALS trial_result · 2023-02-08Clinical Trial Update: Ezetimibe (EZ)/Atorvastatin (Ator) (MK-0653C) vs. Ator in Chinese Hypercholesterolemic Participants (MK-0653C-439) [Phase 3]
Phase 3 trial comparing ezetimibe/atorvastatin (MK-0653C) versus atorvastatin alone in Chinese participants with hypercholesterolemia. Resul…
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CLINICAL_TRIALS trial_result · 2022-12-20Clinical Trial Update: A Clinical Trial to Evaluate the Efficacy and Safety of CKD-391 and CKD-331 in Patients With Primary Hypercholesterolemia [Phase 3]
A Phase 3 trial evaluating CKD-391 and CKD-331 for primary hypercholesterolemia is ongoing with unknown status.
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CLINICAL_TRIALS trial_result · 2022-07-20Clinical Trial Update: A Study to Evaluate the Efficacy and Safety of AD-221 and AD-221A [Phase 3]
Phase 3 clinical trial evaluating the efficacy and safety of AD-221 and AD-221A for primary hypercholesterolemia has been completed.
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CLINICAL_TRIALS trial_result · 2022-07-20Clinical Trial Update: Effect of Amlodipine on the Lipid Profile of Newly Diagnosed Hypertensive Patients [Phase 4]
Phase 4 trial assessing the effect of amlodipine on lipid profile in newly diagnosed hypertensive patients.
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CLINICAL_TRIALS trial_result · 2022-07-15Clinical Trial Update: Dose-ranging Efficacy and Pharmacokinetics Study of Intravenous Atorvastatin in Hypercholesterolemic Patients [Phase 2]
Phase 2 dose-ranging study evaluating intravenous atorvastatin in hypercholesterolemia; results have been posted after completion.
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CLINICAL_TRIALS trial_result · 2022-07-14Clinical Trial Update: Cross-Over Study to Compare the Pharmacokinetics and Pharmacodynamics of LIB003 Process 1 and Process 2 Drug Product [Phase 3]
A completed Phase 3 cross-over trial comparing two production processes (Process 1 vs Process 2) of LIB003 to assess pharmacokinetics and ph…
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CLINICAL_TRIALS trial_result · 2022-05-18Clinical Trial Update: Compare the Efficacy and Safety of 1PC111 With Pitavastatin and Ezetimibe in Patients With Primary Hypercholesterolemia or Mixed Dyslipidemia [Phase 3]
Phase 3 trial comparing 1PC111 with pitavastatin and ezetimibe in primary hypercholesterolemia or mixed dyslipidemia completed.
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CLINICAL_TRIALS trial_result · 2022-04-13Clinical Trial Update: Supplementation of Oil Palm Phenolics to Improve Lipid Profile in Subjects With Minor Hyperlipidaemia [Phase 2]
Phase 2 trial evaluating supplementation of oil palm phenolics to improve lipid profiles in individuals with minor hyperlipidaemia/hyperchol…