Hypercholesterolemia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2024-08-15Clinical Trial Update: Randomized Parallel Group Trial Of The Efficacy And Safety Of Ezetimibe With A Statin Versus Statin Dose Doubling In Patients With Persistent Primary Hypercholesterolemia (0653-152)(COMPLETED) [Phase 4]
A randomized Phase 4 trial comparing ezetimibe added to a statin versus doubling the statin dose in patients with persistent primary hyperch…
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CLINICAL_TRIALS trial_result · 2024-08-15Clinical Trial Update: To Evaluate the Lipid-Lowering Efficacy and Safety of Simvastatin 40 Mg Tablet In Patients With Hypercholesterolemia (0733-264) [Phase 4]
A Phase 4 clinical trial evaluating the lipid-lowering efficacy and safety of simvastatin 40 mg tablets in adults with hypercholesterolemia …
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CLINICAL_TRIALS trial_result · 2024-08-15Clinical Trial Update: Switching to Rosuvastatin Versus Adding Ezetimibe to Atorvastatin Versus Doubling the Dose of Atorvastatin in Patients With Hypercholesterolemia and Risk Factors (P03708) [Phase 4]
Phase 4 trial comparing switching to rosuvastatin, adding ezetimibe to atorvastatin, or doubling the dose of atorvastatin in patients with h…
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CLINICAL_TRIALS trial_result · 2024-08-15Clinical Trial Update: Ezetimibe Plus Simvastatin Versus Simvastatin in Untreated Subjects With High Cholesterol (P03435) [Phase 4]
A Phase 4 trial comparing ezetimibe plus simvastatin versus simvastatin alone in untreated individuals with high cholesterol has completed.
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CLINICAL_TRIALS trial_result · 2024-08-15Clinical Trial Update: MD Ezetimibe Cyclosporine Interaction (0653-057) [Phase 1]
Phase 1 trial update evaluating a potential pharmacokinetic interaction between ezetimibe and cyclosporine in the context of cholesterol man…
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CLINICAL_TRIALS trial_result · 2024-08-15Clinical Trial Update: Comparison of Co-administration of Ezetimibe Plus Simvastatin Versus Simvastatin Alone in Primary Hypercholesterolemia (P03476) [Phase 4]
A Phase 4 trial compared co-administration of ezetimibe with simvastatin versus simvastatin alone in primary hypercholesterolemia; the study…
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CLINICAL_TRIALS trial_result · 2024-08-15Clinical Trial Update: Two Investigational Drugs in Patients With Mixed Hyperlipidemia (0653-036) [Phase 3]
Phase 3 trial evaluating two investigational drugs for mixed hyperlipidemia has completed.
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CLINICAL_TRIALS trial_result · 2024-08-15Clinical Trial Update: Comparison of Ezetimibe Plus Simvastatin Versus Ezetimibe or Simvastatin Alone in Subjects With Primary Hypercholesterolemia (Study P03757)(COMPLETED) [Phase 3]
Phase 3 study P03757 comparing ezetimibe plus simvastatin versus ezetimibe or simvastatin alone in adults with primary hypercholesterolemia …
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CLINICAL_TRIALS trial_result · 2024-08-15Clinical Trial Update: Co-administration Study in Patients With Elevated Cholesterol and Coronary Heart Disease (0653-802)(COMPLETED) [Phase 3]
A Phase 3 co-administration study in patients with hypercholesterolemia and coronary artery disease has completed.
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CLINICAL_TRIALS trial_result · 2024-08-15Clinical Trial Update: Investigational Drug Study in Patients With Elevated Cholesterol and Coronary Heart Disease (0653-801) [Phase 3]
This clinical trial update reports completion of a Phase 3 investigational study in patients with hypercholesterolemia and coronary artery d…
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CLINICAL_TRIALS trial_result · 2024-08-15Clinical Trial Update: EASEGO Study: Doubling of Atorvastatin/Simvastatin or INEGY in Patients With Hypercholesterolemia and Coronary Artery Disease(CAD)(0653A-089) [Phase 4]
The EASEGO Phase 4 trial evaluated doubling the dose of atorvastatin or simvastatin, or a drug called INEGY, in patients with hypercholester…
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CLINICAL_TRIALS trial_result · 2024-08-15Clinical Trial Update: Effect of Ezetimibe Plus Simvastatin on Flow-Mediated Brachial Artery Vasoactivity in Subjects With Primary Hypercholesterolemia (Study P03336) [Phase 3]
A Phase 3 trial evaluating the effect of combining ezetimibe with simvastatin on flow-mediated brachial artery vasoreactivity in people with…
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CLINICAL_TRIALS trial_result · 2024-08-15Clinical Trial Update: Ezetimibe Plus Simvastatin Versus Simvastatin Alone in African-American Subjects With Primary Hypercholesterolemia (P03377) [Phase 4]
Phase 4 trial comparing the addition of ezetimibe to simvastatin versus simvastatin alone in African-American adults with primary hyperchole…
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CLINICAL_TRIALS trial_result · 2024-08-15Clinical Trial Update: A Study to Evaluate Ezetimibe in Korean Patients With Primary Hypercholesterolemia (0653-042) [Phase 3]
A Phase 3 trial evaluating ezetimibe in Korean patients with primary hypercholesterolemia has completed.
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CLINICAL_TRIALS trial_result · 2024-08-15Clinical Trial Update: A Study to Evaluate an Investigational Drug in Patients With Mixed Hyperlipidemia (0653A-071)(COMPLETED) [Phase 3]
A Phase 3 clinical trial evaluating an investigational drug (0653A-071) for mixed hyperlipidemia has completed; the study enrolled patients …
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CLINICAL_TRIALS trial_result · 2024-08-15Clinical Trial Update: Study to Evaluate the Cholesterol Lowering Effects of Two Marketed Drugs in Patients With Elevated Cholesterol Levels (0653A-058) [Phase 3]
An update on a Phase 3 clinical trial evaluating the cholesterol-lowering effects of two marketed drugs in adults with elevated cholesterol;…
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CLINICAL_TRIALS trial_result · 2024-08-15Clinical Trial Update: Co-administration Study in Patients With Elevated Cholesterol and Coronary Heart Disease (0653-803) [Phase 3]
A Phase 3 co-administration trial in patients with elevated cholesterol and coronary disease has completed.
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CLINICAL_TRIALS trial_result · 2024-08-15Clinical Trial Update: An Extension Study of An Investigational Drug in Patients With Hypercholesterolemia (0653A-038)(COMPLETED) [Phase 3]
The extension study (0653A-038) of an investigational drug for hypercholesterolemia has completed, with Organon and Co listed as sponsor.
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CLINICAL_TRIALS trial_result · 2024-08-07Clinical Trial Update: Study to Assess the Real World Effectiveness of Inclisiran in Chinese Adult Patients With Primary Hypercholesterolemia or Mixed Dyslipidemia
A completed real-world study evaluating Inclisiran in Chinese adults with primary hypercholesterolemia or mixed dyslipidemia.
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CLINICAL_TRIALS trial_result · 2024-07-18Clinical Trial Update: A Real-world Study of Inclisiran Adherence, Treatment Patterns, Patient Characteristics, and Effectiveness in ASCVD Patients With Hypercholesterolemia, ASCVD-risk Equivalent Patients With Hypercholesterolemia and Familial Hypercholesterolemia
This completed real-world study evaluated adherence, treatment patterns, patient characteristics, and effectiveness of Inclisiran in patient…
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CLINICAL_TRIALS trial_result · 2024-07-03Clinical Trial Update: Study to Evaluate the Effect of Obicetrapib in Combination With Ezetimibe as an Adjunct to HIS Therapy [Phase 2]
Phase 2 study evaluating obicetrapib in combination with ezetimibe as an adjunct to HIS therapy has completed, with results posted in July 2…
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CLINICAL_TRIALS trial_result · 2024-06-27Clinical Trial Update: Study to Evaluate the Bioequivalence of "Crecheck Tablet 2.5 mg (Rosuvastatin Calcium)" and "Crestor Tablet 5 mg (Rosuvastatin Calcium)" in Healthy Adult Subjects [Phase 1]
Phase 1 bioequivalence study comparing Crecheck Tablet 2.5 mg rosuvastatin calcium with Crestor Tablet 5 mg rosuvastatin calcium in healthy …
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CLINICAL_TRIALS trial_result · 2024-06-20Clinical Trial Update: HealthMatters@24/7 eLearning for People Supporting Adults With Intellectual and Developmental Disabilities [NA]
The HealthMatters@24/7 eLearning trial for supporting adults with intellectual and developmental disabilities has completed, studying outcom…
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CLINICAL_TRIALS trial_result · 2024-06-11Clinical Trial Update: Randomized Study of Obicetrapib as an Adjunct to Statin Therapy [Phase 2]
Phase 2 randomized study of Obicetrapib added to statin therapy has completed with results posted.
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CLINICAL_TRIALS trial_result · 2024-06-11Clinical Trial Update: Evaluating the Efficacy of AI-Guided (GenAIS TM) vs. Standard Physician-Guided Dietary Supplement Prescriptions for Lowering LDL Cholesterol in Hypercholesterolemic Patients [NA]
A completed clinical trial evaluated whether AI-guided dietary supplement prescriptions (GenAIS) lower LDL cholesterol more effectively than…