Hypercholesterolemia
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CLINICAL_TRIALS trial_result · 2024-10-31Clinical Trial Update: A Study of IBI306 in Participants With Hypercholesterolemia [Phase 3]
A Phase 3 trial evaluating IBI306 in participants with hypercholesterolemia has completed.
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CLINICAL_TRIALS trial_result · 2024-10-23Clinical Trial Update: Trial to Evaluate Efficacy and Safety of LIB003 and Inclisiran in High-risk CVD Patients [Phase 3]
Phase 3 trial evaluating LIB003 in combination with Inclisiran for efficacy and safety in high-risk cardiovascular disease patients has comp…
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CLINICAL_TRIALS trial_result · 2024-10-23Clinical Trial Update: A Study of Enlicitide Chloride (MK-0616) in Healthy Participants and Participants Taking Statins (MK-0616-012) [Phase 1]
Phase 1 clinical trial update for Enlicitide Chloride (MK-0616) in healthy participants and those on statins (MK-0616-012); the study has co…
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CLINICAL_TRIALS trial_result · 2024-10-21Clinical Trial Update: Unravelling the Impact of Diet on Cardiovascular Health in Treated Heterozygous Familial Hypercholesterolemia. [NA]
The clinical trial investigating how diet affects cardiovascular health in individuals with treated heterozygous familial hypercholesterolem…
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CLINICAL_TRIALS trial_result · 2024-10-18Clinical Trial Update: A Study to Evaluate the Efficacy and Safety of BR1017A and BR1017B Combination Therapy in Essential Hypertension Patients With Primary Hypercholesterolemia [Phase 3]
A Phase 3 clinical trial evaluating the efficacy and safety of BR1017A and BR1017B in essential hypertension with primary hypercholesterolem…
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CLINICAL_TRIALS trial_result · 2024-10-10Clinical Trial Update: Adult Subjects With Elevated Low-Density Lipoprotein-Cholesterol to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamic Effects [Phase 1]
This clinical trial update reports a Phase 1 study in adults with elevated LDL-cholesterol to evaluate the safety, tolerability, pharmacokin…
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CLINICAL_TRIALS trial_result · 2024-09-27Clinical Trial Update: A Dose-Finding Study in Japanese Patients to Evaluate the Effect of Obicetrapib as an Adjunct to Stable Statin Therapy. [Phase 2]
A Phase 2 dose-finding study in Japanese patients evaluated obicetrapib as an adjunct to stable statin therapy for dyslipidemia/hypercholest…
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CLINICAL_TRIALS trial_result · 2024-09-19Clinical Trial Update: A Study of MK-0616 in Healthy Adult Participants (MK-0616-009) [Phase 1]
Phase 1 clinical trial update for MK-0616 in healthy adult participants. The study lists hypercholesterolemia as the associated condition an…
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CLINICAL_TRIALS trial_result · 2024-09-19Clinical Trial Update: Kefir Cholesterol Lowering Pilot Study [NA]
A completed pilot clinical trial sponsored by the University of Alberta assessed whether kefir can lower cholesterol in adults with hypercho…
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CLINICAL_TRIALS trial_result · 2024-08-30Clinical Trial Update: The Effect of Progressive Resistance Exercise Training (PRET) on CVRF in Adults With ID. [NA]
This clinical trial update reports a completed study examining the effect of progressive resistance exercise training on cardiovascular risk…
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CLINICAL_TRIALS trial_result · 2024-08-23Clinical Trial Update: A Study of MK0653A (Ezetimibe (+) Simvastatin) in Patients With Hypercholesterolemia (0653A-038) [Phase 3]
Phase 3 clinical trial update for MK0653A (ezetimibe plus simvastatin) in hypercholesterolemia; the study status is completed.
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CLINICAL_TRIALS trial_result · 2024-08-23Clinical Trial Update: U of A/ U of M Beans and Peas Health Claim Project [NA]
A completed clinical trial update from the University of Alberta and University of Manitoba on a beans and peas health claim project investi…
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CLINICAL_TRIALS trial_result · 2024-08-15Clinical Trial Update: A Research Study to Evaluate MK0653 (Ezetimibe) and Simvastatin, Given Together and Alone, on Intestinal Absorption of Cholesterol (0653-050)(COMPLETED) [Phase 3]
Phase 3 trial evaluating ezetimibe (MK0653) with and without simvastatin on intestinal absorption of cholesterol has completed.
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CLINICAL_TRIALS trial_result · 2024-08-15Clinical Trial Update: Ezetimibe Plus Atorvastatin Versus Atorvastatin in Untreated Subjects With High Cholesterol (P03434) [Phase 4]
A Phase 4 trial comparing ezetimibe added to atorvastatin versus atorvastatin alone in untreated individuals with high cholesterol has compl…
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CLINICAL_TRIALS trial_result · 2024-08-15Clinical Trial Update: Effectiveness of Two Approved Drugs in Lowering High Cholesterol (0733-224) [Phase 3]
Phase 3 clinical trial update assessing the effectiveness of two approved cholesterol-lowering drugs in hypercholesterolemia.
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CLINICAL_TRIALS trial_result · 2024-08-15Clinical Trial Update: An Investigational Drug Study in Patients With Elevated Cholesterol and Coronary Heart Disease (0653-804)(COMPLETED) [Phase 3]
A Phase 3 investigational drug study evaluating treatment for elevated cholesterol and coronary disease has completed.
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CLINICAL_TRIALS trial_result · 2024-08-15Clinical Trial Update: Study of Ezetimibe and Fenofibrate in Patients With Mixed Hyperlipidemia (0653-036)(COMPLETED) [Phase 3]
A Phase 3 study evaluating the combination of ezetimibe and fenofibrate in patients with mixed hyperlipidemia has completed.
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CLINICAL_TRIALS trial_result · 2024-08-15Clinical Trial Update: Comparing an Investigational Medication Versus an Approved Medication in Reducing Cholesterol Levels (0653-025) [Phase 3]
Phase 3 trial comparing an investigational cholesterol-lowering medication to an approved therapy in hypercholesterolemia; the study has com…
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CLINICAL_TRIALS trial_result · 2024-08-15Clinical Trial Update: Effect of Ezetimibe Plus Simvastatin Versus Simvastatin Alone on Atherosclerosis in the Carotid Artery (ENHANCE)(P02578) [Phase 3]
A Phase 3 trial comparing ezetimibe plus simvastatin versus simvastatin alone for progression of carotid artery atherosclerosis has complete…
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CLINICAL_TRIALS trial_result · 2024-08-15Clinical Trial Update: Observational Study to Evaluate LDL-C Lowering Effect of Ezetimibe (0653-070) [Phase 3]
This update documents the completion of a Phase 3 observational study evaluating the LDL-C lowering effect of ezetimibe in individuals with …
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CLINICAL_TRIALS trial_result · 2024-08-15Clinical Trial Update: Cholesterol Lowering Level of MK0653A+Simvastatin in Patients With Hypercholesterolemia and Atherosclerotic or Coronary Vascular Disease (0653A-806)(COMPLETED) [Phase 3]
A completed Phase 3 trial evaluated MK0653A in combination with simvastatin for cholesterol lowering in patients with hypercholesterolemia a…
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CLINICAL_TRIALS trial_result · 2024-08-15Clinical Trial Update: TWICE (Ezetimibe Together With Any Statin Cholesterol Enhancement)(0653-060) [Phase 3]
Completed Phase 3 trial TWICE evaluated ezetimibe together with any statin for lowering cholesterol in hypercholesterolemia and hyperlipidem…
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CLINICAL_TRIALS trial_result · 2024-08-15Clinical Trial Update: A Multicenter Study to Evaluate the Cholesterol Lowering Effects of Two Marketed Products in Patients With Type 2 Diabetes Mellitus and Hypercholesterolemia (MK-0653A-077) [Phase 3]
Phase 3 multicenter trial completed to evaluate the cholesterol-lowering effects of two marketed products in patients with Type 2 diabetes m…
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CLINICAL_TRIALS trial_result · 2024-08-15Clinical Trial Update: Study of an Approved Drug With a Statin (a Medication That Lowers Cholesterol Levels) as Compared to Statin Therapy Alone in Patients With High Cholesterol (0653-040) [Phase 3]
Phase 3 trial evaluating adding an approved lipid-lowering drug to statin therapy versus statin therapy alone in adults with hypercholestero…
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CLINICAL_TRIALS trial_result · 2024-08-15Clinical Trial Update: A 12 Week Study of MK0653A in Patients Who Have Been Hospitalized for a Possible Heart Problem (0653A-808) [Phase 3]
Phase 3 trial status update for MK0653A in patients with hypercholesterolemia hospitalized for a possible heart problem; the study has compl…