Hypercholesterolemia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2025-06-11Clinical Trial Update: Evaluate the Effect of Obicetrapib in Patients With HeFH on Top of Maximum Tolerated Lipid-Modifying Therapies. [Phase 3]
A Phase 3 trial evaluating Obicetrapib in patients with familial hypercholesterolemia on maximally tolerated lipid-modifying therapy has com…
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CLINICAL_TRIALS trial_result · 2025-06-08Clinical Trial Update: How Cricket Powder Affects Gut Microbiome and Cholesterol Metabolism [NA]
This update reports on a completed clinical trial evaluating the effects of cricket powder on gut microbiome and cholesterol metabolism in p…
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CLINICAL_TRIALS trial_result · 2025-05-28Clinical Trial Update: Evaluation of Green Tea for Improving Blood Lipid Profile [NA]
A Taipei Medical University-backed clinical trial is evaluating whether green tea can improve blood lipid profiles in hypercholesterolemia; …
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CLINICAL_TRIALS trial_result · 2025-05-22Clinical Trial Update: Study of the Effects of Yerba Mate on Cardiometabolic Health [NA]
A completed clinical trial evaluating the effects of Yerba Mate on cardiometabolic health, sponsored by Instituto de Ciencia y Tecnología de…
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CLINICAL_TRIALS trial_result · 2025-05-21Clinical Trial Update: Impact of Phytosterol-Rich Extract on Lipid Profile [NA]
This clinical trial update describes an investigation of a phytosterol-rich extract and its effect on lipid profiles in individuals with ele…
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CLINICAL_TRIALS trial_result · 2025-05-08Clinical Trial Update: A Study of VERVE-101 in Patients With Familial Hypercholesterolemia and Cardiovascular Disease [Phase 1]
Phase 1 trial update reporting completion of the study of VERVE-101 in patients with heterozygous familial hypercholesterolemia and cardiova…
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CLINICAL_TRIALS trial_result · 2025-05-01Clinical Trial Update: Evaluation of the Functionality of an Extract Rich in Phytosterols and Phytostanols on Parameters Related to the Lipid Profile of Individuals With Hypercholesterolemia, Mainly in the Levels of Total Cholesterol, LDL Cholesterol and Oxidized LDL [NA]
A completed clinical trial evaluated the effect of a phytosterol and phytostanol-rich extract on lipid parameters (total cholesterol, LDL ch…
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CLINICAL_TRIALS trial_result · 2025-04-20Clinical Trial Update: Efficacy and Safety of Inclisiran as Monotherapy in Chinese Adults With Low or Moderate ASCVD Risk and Elevated Low-density Lipoprotein Cholesterol. [Phase 3]
Phase 3 trial evaluating inclisiran as monotherapy in Chinese adults with elevated LDL-C and low-to-moderate ASCVD risk shows efficacy and s…
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CLINICAL_TRIALS trial_result · 2025-04-13Clinical Trial Update: Examination of the Effects of Chromium Levels on Glucose Metabolism, Lipid Metabolism, Morbidity and Mortality Rates in Patients Followed in Intensive Care Unit
A completed clinical trial (NCT06334042) assessed how chromium levels influence glucose and lipid metabolism as well as morbidity and mortal…
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CLINICAL_TRIALS trial_result · 2025-04-11Clinical Trial Update: Single Dose Oral Bioequivalence Study of Bempedoic Acid 180 mg Film Coated Tablet and Nilemdo® (Bempedoic Acid) 180 mg Film-coated Tablets in Healthy Adult Human Subjects Under Fasting Conditions. [Phase 1]
A Phase 1 bioequivalence study comparing a single-dose 180 mg bempedoic acid film-coated tablet to Nilemdo 180 mg film-coated tablets was co…
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CLINICAL_TRIALS trial_result · 2025-04-08Clinical Trial Update: Peripheral Treg Cell Senescence & Serum Total Cholesterol Level
This completed clinical trial from Tianjin Medical University examined the relationship between peripheral T regulatory cell senescence and …
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CLINICAL_TRIALS trial_result · 2025-04-03Clinical Trial Update: the Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamic Effects in Adult Subjects With Elevated LDL-C [Phase 1]
Phase 1 study evaluating safety, tolerability, pharmacokinetics, and pharmacodynamic effects of a therapy aimed at lowering LDL-C in adults …
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CLINICAL_TRIALS trial_result · 2025-03-27Clinical Trial Update: To Compare the Effect of Concomitant Administration of Probucol and Cilostazol With Probucol Single Treatment on the Atherosclerosis Related Markers (Including the Thickness of the Achilles Tendon) and Evaluate Safety (Based on Atorvastatin Treatment) in Severe Hypercholesterolemia Subject [Phase 4]
A Phase 4 clinical trial update comparing concurrent probucol and cilostazol versus probucol alone, assessing atherosclerosis-related marker…
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CLINICAL_TRIALS trial_result · 2025-03-24Clinical Trial Update: Non-interventional Study on the Monthly Administration of 300 mg AliRocumab (PRALUENT®) With the 2 ml SYDNEY Auto-injector
This entry reports the completion of a non-interventional study evaluating monthly 300 mg alirocumab (PRALUENT) administered using the SYDNE…
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CLINICAL_TRIALS trial_result · 2025-03-13Clinical Trial Update: A Confirmatory Trial of ETC-1002 in Patients With Hyper-LDL Cholesterolemia [Phase 3]
ETC-1002, a lipid-lowering agent, completed a confirmatory Phase 3 trial in patients with hyper-LDL cholesterolemia. Results from the comple…
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CLINICAL_TRIALS trial_result · 2025-03-05Clinical Trial Update: Clinical Trials of Effects of Time Restricted Eating on Health Parameters in Adults [NA]
This completed clinical trial evaluated the effects of time-restricted eating on multiple health parameters in adults. The study assessed ob…
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CLINICAL_TRIALS trial_result · 2025-02-28Clinical Trial Update: A Study of PCSK9 Inhibitor AK102 in Healthy Subjects [Phase 1]
Phase 1 trial evaluating the PCSK9 inhibitor AK102 in healthy subjects has completed.
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CLINICAL_TRIALS trial_result · 2025-02-17Clinical Trial Update: Enlicitide Decanoate (MK-0616 Oral PCSK9 Inhibitor) Renal Impairment Study (MK-0616-020) [Phase 1]
Phase 1 renal impairment study of MK-0616 (Enlicitide Decanoate), an oral PCSK9 inhibitor, in hypercholesterolemia has completed with result…
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CLINICAL_TRIALS trial_result · 2025-02-13Clinical Trial Update: Phase 2a Study to Assess CIVI 007 in Patients on a Background of Statin Therapy [Phase 2]
Phase 2a trial evaluating CIVI 007 in hypercholesterolemia patients on background statin therapy; results from the study have been completed…
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CLINICAL_TRIALS trial_result · 2025-02-06Clinical Trial Update: A Study on Efficacy and Safety of HST101 in Chinese Patients with Hypercholesterolemia [Phase 3]
A Phase 3 study evaluating the efficacy and safety of HST101 in Chinese patients with hypercholesterolemia and related dyslipidemias; the tr…
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CLINICAL_TRIALS trial_result · 2025-01-22Clinical Trial Update: Multicenter, Prospective, Non-interventional, Observational Study to Confirm the Long-term Efficacy and Safety of Rosuampin Tab. in Patients With Hypertension and Hypercholesterolemia
A multicenter, non-interventional observational study completed to assess the long-term efficacy and safety of Rosuampin Tablet in patients …
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CLINICAL_TRIALS trial_result · 2024-12-16Clinical Trial Update: Anti-eryptotic Effect of a Food Supplement with Plants Sterols in Hypercholesterolemia Treated with Statins [NA]
A University of Valencia–sponsored clinical trial evaluating a plant sterol–containing food supplement for anti-eryptotic effects in hyperch…
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CLINICAL_TRIALS trial_result · 2024-12-09Clinical Trial Update: Evaluation of Consuming Olive Extract on Total Cholesterol Levels [NA]
A completed clinical trial evaluated whether consuming olive extract affects total cholesterol levels in people with metabolic syndrome and …
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CLINICAL_TRIALS trial_result · 2024-11-21Clinical Trial Update: Long Term Post Marketing Specified Drug Use Result Survey for Evolocumab in Japan
A long-term post-marketing specified drug use survey for evolocumab conducted in Japan has completed.
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CLINICAL_TRIALS trial_result · 2024-11-19Clinical Trial Update: Impact of Alpine Dairy Products on Blood Lipid Levels [NA]
This completed clinical trial from the University of Fribourg studied whether Alpine dairy products influence blood lipid levels in people w…