Hypercholesterolemia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2009-03-16Clinical Trial Update: Rosuvastatin Versus Atorvastatin in the Treatment of Hypercholesterolaemia in African American Subjects(ARIES) [Phase 3]
ARIES is a Phase 3 head-to-head trial comparing rosuvastatin to atorvastatin in African American adults with hypercholesterolemia, and the s…
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CLINICAL_TRIALS trial_result · 2009-03-16Clinical Trial Update: STELLAR-Rosuvastatin vs. Atorvastatin, Pravastatin, Simvastatin Across Dose Ranges [Phase 3]
Phase 3 trial comparing rosuvastatin with atorvastatin, pravastatin, and simvastatin across dose ranges has completed.
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CLINICAL_TRIALS trial_result · 2009-03-16Clinical Trial Update: Mercury II - Compare the Efficacy and Safety of Lipid Lowering Agents Atorvastatin and Simvastatin With Rosuvastatin in High Risk Subjects With Type IIa and IIb Hypercholesterolemia [Phase 3]
Phase 3 Mercury II trial compares the efficacy and safety of atorvastatin, simvastatin, and rosuvastatin in high-risk subjects with Type IIa…
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CLINICAL_TRIALS trial_result · 2009-03-16Clinical Trial Update: Assessment of the Efficacy of Rosuvastatin in Patient Groups With a Dissimilar Risk Profile in an Observational Study (HEROS)
This is a clinical trial update from the observational HEROS study assessing the efficacy of rosuvastatin across patient groups with differe…
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CLINICAL_TRIALS trial_result · 2009-03-16Clinical Trial Update: Comparing the Efficacy and Safety of Rosuvastatin With Atorvastatin and Simvastatin (SOLAR) [Phase 3]
A Phase 3 trial (SOLAR) compared rosuvastatin with atorvastatin and simvastatin for efficacy and safety in hypercholesterolemia, and the stu…
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CLINICAL_TRIALS trial_result · 2009-03-16Clinical Trial Update: OLE Study to Evaluate Safety / Efficacy of ZD4522 [Phase 3]
An open-label extension (OLE) Phase 3 study evaluating the safety and efficacy of ZD4522 in hypercholesterolemia has completed.
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CLINICAL_TRIALS trial_result · 2009-03-16Clinical Trial Update: Treatment of Hypercholesterolaemia in South Asian Subjects (IRIS) [Phase 3]
A Phase 3 trial update from AstraZeneca on treating hypercholesterolemia in South Asian subjects; the study status is completed, but results…
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CLINICAL_TRIALS trial_result · 2009-03-16Clinical Trial Update: Treatment of Hypercholesterolaemia in Hispanic Subjects (STARSHIP) [Phase 3]
Phase 3 clinical trial update (STARSHIP) on treatment of hypercholesterolemia and dyslipidemia in Hispanic subjects; the study status is com…
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CLINICAL_TRIALS trial_result · 2009-03-09Clinical Trial Update: Study of the Effects of a Mineralized Water Ingestion Upon Lipidic Absorption Mechanisms [NA]
A completed clinical trial studying how mineralized water affects lipid absorption. The trial targeted individuals with moderate hypercholes…
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CLINICAL_TRIALS trial_result · 2009-02-16Clinical Trial Update: Safety and Efficacy of Long-Term Treatment With Atorvastatin in Patients With Primary Biliary Cirrhosis [Phase 3]
A Phase 3 trial assessed the safety and efficacy of long-term atorvastatin treatment in patients with primary biliary cholangitis (including…
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CLINICAL_TRIALS trial_result · 2009-02-13Clinical Trial Update: Study to Assess if Internet-Based Tailored Advice Could Modify Behaviour to Improve Health [NA]
A completed clinical trial evaluating whether internet-based tailored advice can modify behavior to improve health in hypercholesterolemia. …
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CLINICAL_TRIALS trial_result · 2009-02-06Clinical Trial Update: Evaluation of Crestor® (Rosuvastatin) in Daily Practice
A completed clinical trial evaluating Crestor (rosuvastatin) in daily practice for hypercholesterolemia.
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CLINICAL_TRIALS trial_result · 2009-01-21Clinical Trial Update: Barley Protein and CVD [Phase 2]
Phase 2 trial evaluating barley protein for cardiovascular disease has completed, with results related to hypercholesterolemia and cardiovas…
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CLINICAL_TRIALS trial_result · 2008-12-25Clinical Trial Update: Fluvastatin 80 mg Ret. vs Combination With Ezetimibe 10 mg in Patients With High Cardiovascular Risk [Phase 4]
A Phase 4 trial compares high-dose fluvastatin monotherapy (80 mg) to combination therapy with ezetimibe (10 mg) in patients at high cardiov…
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CLINICAL_TRIALS trial_result · 2008-12-16Clinical Trial Update: A Study Evaluating the Safety and Efficacy of AVE5530 (4 Weeks) in Patients With Mild to Moderate Hypercholesterolemia [Phase 2]
A Phase 2 study evaluating AVE5530 over 4 weeks in patients with mild to moderate hypercholesterolemia has completed. The update reports saf…
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CLINICAL_TRIALS trial_result · 2008-12-01Clinical Trial Update: LDL-Cholesterol Lowering Effect of KB2115 as Add on to Ezetimibe [Phase 2]
A Phase 2 trial evaluating KB2115 as an add-on to ezetimibe in hypercholesterolemia has completed, assessing its LDL-cholesterol lowering ef…
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CLINICAL_TRIALS trial_result · 2008-11-27Clinical Trial Update: A Study to Evaluate the Effects of Extended Release (ER) Niacin/Laropiprant, Laropiprant, ER Niacin, and Placebo on Urinary Prostanoid Metabolites in Subjects With High Cholesterol (0524A-075)(COMPLETED) [Phase 1]
Phase 1 trial evaluating extended-release niacin/laropiprant, laropiprant, ER niacin, and placebo on urinary prostanoid metabolites in adult…
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CLINICAL_TRIALS trial_result · 2008-11-25Clinical Trial Update: Effectiveness of Creatine in Preventing Muscle Aching From Cholesterol-Lowering Statin Drugs [NA]
A completed clinical trial from The Cleveland Clinic evaluated whether creatine can prevent muscle aching and related symptoms in people tak…
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CLINICAL_TRIALS trial_result · 2008-11-05Clinical Trial Update: Ezetimibe Plus (+) Simvastatin Versus Atorvastatin Comparative Study (0653A-092)(COMPLETED) [Phase 4]
A Phase 4 randomized trial comparing ezetimibe plus simvastatin versus atorvastatin in patients with hypercholesterolemia has completed with…
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CLINICAL_TRIALS trial_result · 2008-10-21Clinical Trial Update: Eprotirome for the Treatment of Dyslipidemia, Efficacy and Safety 12-Week, Phase ii Study to Assess the Safety and Efficacy of KB2115 in Patients With Primary Hypercholesterolemia [Phase 2]
This clinical trial update reports the completion of a 12-week Phase II study evaluating the safety and efficacy of KB2115 (eprotirome) in p…
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CLINICAL_TRIALS trial_result · 2008-10-06Clinical Trial Update: DNA Diagnostic System for Statin Safety and Efficacy
A clinical trial update from Genomas, Inc about a DNA diagnostic system designed to evaluate statin safety and efficacy in individuals with …
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CLINICAL_TRIALS trial_result · 2008-09-30Clinical Trial Update: The Effect of Fasudil on Vascular Function in Humans [Phase 2]
Phase 2 clinical trial evaluating fasudil for improving vascular function in adults with atherosclerosis and hypercholesterolemia completed.
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CLINICAL_TRIALS trial_result · 2008-09-03Clinical Trial Update: Effects of Atorvastatin on Adiponectin Levels and Insulin Sensitivity In Hypercholesterolemic Patients [Phase 4]
This Phase 4 trial investigates whether atorvastatin modulates adiponectin levels and improves insulin sensitivity in adults with hyperchole…
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CLINICAL_TRIALS trial_result · 2008-08-29Clinical Trial Update: Differential Metabolic Effects of Statins
This clinical trial update summarizes observed differential metabolic effects among various statins in individuals with hypercholesterolemia…
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CLINICAL_TRIALS trial_result · 2008-07-04Clinical Trial Update: Correlation of Flicker Induced and Flow Mediated Vasodilatation in Patients With Endothelial Dysfunction and Healthy Volunteers. [NA]
The completed trial assessed the correlation between flicker-induced vasodilatation and flow-mediated vasodilatation in patients with endoth…