Hypercholesterolemia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2009-10-06Clinical Trial Update: Ezetimibe and Atorvastatin vs. Atorvastatin in Patients Age 65 and Older at High Risk for Coronary Heart Disease (CHD)(0653-112) [Phase 3]
This Phase 3 trial in patients aged 65 and older with hypercholesterolemia at high risk for coronary heart disease compared ezetimibe added …
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CLINICAL_TRIALS trial_result · 2009-10-05Clinical Trial Update: Rosuvastatin Efficacy and Safety Evaluation in Hypercholesterolaemic Patients
A completed clinical trial evaluating the efficacy and safety of rosuvastatin in patients with hypercholesterolemia.
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CLINICAL_TRIALS trial_result · 2009-09-14Clinical Trial Update: Omentectomy for the Treatment of Diabetes Mellitus Type 2 [Phase 1]
A Phase 1 trial evaluating omentectomy as a treatment for type 2 diabetes has completed.
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CLINICAL_TRIALS trial_result · 2009-09-10Clinical Trial Update: Tolerability and Lipid Lowering Effect of Weekly/Biweekly Crestor in Statin Intolerant Patients Treated With Zetia [Phase 4]
This Phase 4 trial update assesses tolerability and lipid-lowering effects of weekly or biweekly rosuvastatin in statin-intolerant patients …
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CLINICAL_TRIALS trial_result · 2009-09-04Clinical Trial Update: Effects of Ezetimibe on the Absorption of Oxidized Cholesterol [Phase 4]
Phase 4 trial update on how ezetimibe affects absorption of oxidized cholesterol in hypercholesterolemia patients; results posted in 2009.
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CLINICAL_TRIALS trial_result · 2009-09-02Clinical Trial Update: Carotid IMT (Intima Media Thickening) Study (0524A-041)(TERMINATED) [Phase 3]
A Phase 3 trial examining carotid intima-media thickness in patients with hypercholesterolemia (familial) sponsored by Merck was terminated.…
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CLINICAL_TRIALS trial_result · 2009-08-25Clinical Trial Update: The Effects of Ezetimibe/Simvastatin 10/20 mg Versus Simvastatin 40 mg in High Cholesterol and Coronary Heart Disease Study (P04039AM2)(COMPLETED) [Phase 4]
Completed Phase 4 trial comparing ezetimibe/simvastatin 10/20 mg to simvastatin 40 mg in patients with hypercholesterolemia and coronary art…
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CLINICAL_TRIALS trial_result · 2009-08-17Clinical Trial Update: A Study to Determine the Number of Patients Who Reach Optimal Cholesterol Levels on Each of Three Different Treatments (0653A-121) [Phase 3]
This Phase 3 trial compares three treatments for hypercholesterolemia to determine how many patients reach optimal cholesterol levels; resul…
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CLINICAL_TRIALS trial_result · 2009-08-04Clinical Trial Update: Ezetimibe/Simvastatin in Patients With Metabolic Syndrome (0653A-107)(COMPLETED) [Phase 3]
Phase 3 clinical trial of ezetimibe/simvastatin in patients with metabolic syndrome completed; results posted in 2009.
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CLINICAL_TRIALS trial_result · 2009-08-03Clinical Trial Update: To Evaluate Ezetimibe/Simvastatin and Niacin (Extended Release Tablet) in Patients With Type IIa or Type IIb Hyperlipidemia (0653A-091)(COMPLETED) [Phase 3]
A Phase 3 trial assessed the lipid-lowering effects of combining ezetimibe/simvastatin with extended-release niacin in patients with Type II…
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CLINICAL_TRIALS trial_result · 2009-08-03Clinical Trial Update: Evaluation of the LDL-C Lowering Effects of Ezetimibe Achieved in Co-administration Therapy With Statins in an Indonesian Population (Study P04276)(COMPLETED)
A completed clinical trial evaluating the LDL-C lowering effects of ezetimibe when co-administered with statins in an Indonesian population.
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CLINICAL_TRIALS trial_result · 2009-07-31Clinical Trial Update: Study of Extended Release Niacin/Laropiprant on Lipids (0524A-067) [Phase 3]
A Phase 3 study evaluating extended-release niacin with laropiprant for lipid management in adults with primary hypercholesterolemia or mixe…
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CLINICAL_TRIALS trial_result · 2009-07-14Clinical Trial Update: Evaluation of the Safety, Tolerability and Efficacy of Ezetimibe on a Select Population of Filipinos With Hypercholesterolemia (Study P04748)(COMPLETED)
Clinical trial evaluating safety, tolerability, and efficacy of ezetimibe in a specific Filipino population with hypercholesterolemia has co…
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CLINICAL_TRIALS trial_result · 2009-07-08Clinical Trial Update: To Evaluate Ezetimibe Plus Atorvastatin Versus Atorvastatin in Patients With High Cholesterol Not Controlled on Atorvastatin 20 mg (0653-079)(COMPLETED) [Phase 3]
Phase 3 trial evaluating ezetimibe added to atorvastatin versus atorvastatin alone (20 mg) in patients with high cholesterol not adequately …
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CLINICAL_TRIALS trial_result · 2009-06-18Clinical Trial Update: Efficacy of Sterol-Fortified Low Fat Soy Beverage on Cholesterol Metabolism, Inflammation and Oxidative Status in Humans - Study II [Phase 1, Phase 2]
Completed Phase 1/2 clinical trial evaluating a sterol-fortified low-fat soy beverage for its effects on cholesterol metabolism, inflammatio…
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CLINICAL_TRIALS trial_result · 2009-06-10Clinical Trial Update: A Study to Assess the Cholesterol Lowering Effect of an Ezetimibe/Simvastatin Combination Tablet Compared to Another Cholesterol Lowering Drug in Patients With High Cholesterol and With High Cardiovascular Risk (0653A-809)(COMPLETED) [Phase 3]
Phase 3 trial comparing an ezetimibe/simvastatin combination tablet to a different cholesterol-lowering drug in patients with hypercholester…
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CLINICAL_TRIALS trial_result · 2009-05-28Clinical Trial Update: Effect of Plant Stanol Ester-Containing Spread on Estimated Cardiovascular Risk in Comparison to Mediterranean Diet [Phase 4]
Phase 4 trial comparing plant stanol ester-containing spread to a Mediterranean diet for estimated cardiovascular risk in people with high c…
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CLINICAL_TRIALS trial_result · 2009-05-20Clinical Trial Update: Influence of Simvastatin on Apolipoprotein B-100 (apoB-100) Secretion [NA]
A completed clinical trial assessed whether simvastatin influences apolipoprotein B-100 secretion in hypercholesterolemia.
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CLINICAL_TRIALS trial_result · 2009-05-13Clinical Trial Update: Effect of MK0524A on Cholesterol Levels (0524A-048) [Phase 3]
Phase 3 clinical trial evaluating MK0524A's effect on cholesterol levels in patients with hypercholesterolemia and hyperlipidemia; the study…
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CLINICAL_TRIALS trial_result · 2009-04-13Clinical Trial Update: To Evaluate Ezetimibe Plus Atorvastatin Versus Atorvastatin in Patients With High Cholesterol Not Controlled on Atorvastatin 40 mg (0653-090) [Phase 3]
Phase 3 trial evaluating whether adding ezetimibe to atorvastatin 40 mg improves lipid control in patients with high cholesterol not adequat…
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CLINICAL_TRIALS trial_result · 2009-04-13Clinical Trial Update: A Randomized Study To Evaluate Efficacy And Safety Of A Fixed Combination Therapy Of Amlodipine And Atorvastatin [Phase 3]
Phase 3 randomized trial evaluating the fixed combination of amlodipine and atorvastatin for hypertension and hypercholesterolemia; complete…
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CLINICAL_TRIALS trial_result · 2009-04-09Clinical Trial Update: C-Control: Efficacy and Safety of Therapy With Rosuvastatin in Statin-Naive and in Statin-Switched Patients
Clinical trial update reporting efficacy and safety of rosuvastatin in statin-naive and statin-switched patients with hypercholesterolemia.
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CLINICAL_TRIALS trial_result · 2009-03-26Clinical Trial Update: Compare the Safety & Efficacy of Rosuvastatin 40mg in Combination With Ezetimibe 10mg [Phase 3]
A Phase 3 trial completed evaluating the safety and efficacy of rosuvastatin 40 mg in combination with ezetimibe 10 mg in patients with high…
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CLINICAL_TRIALS trial_result · 2009-03-26Clinical Trial Update: Rosuvastatin ORBITAL Germany [Phase 3]
This update indicates the Phase 3 Rosuvastatin ORBITAL trial in Germany has completed, evaluating rosuvastatin for hypercholesterolemia.
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CLINICAL_TRIALS trial_result · 2009-03-16Clinical Trial Update: Polaris - Crestor 40 mg vs Atorvastatin 80 mg for 26 Weeks [Phase 3]
Phase 3 trial update comparing Crestor (rosuvastatin) 40 mg versus atorvastatin (Lipitor) 80 mg over 26 weeks in patients with hypercholeste…