Hypercholesterolemia
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CLINICAL_TRIALS trial_result · 2013-04-24Clinical Trial Update: Pharmacodynamic Clinical Trial of Cardiovascular Polypill on LDL Cholesterol [Phase 2]
A Phase 2 pharmacodynamic study evaluating a cardiovascular polypill’s effect on LDL cholesterol has been terminated.
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CLINICAL_TRIALS trial_result · 2013-04-09Clinical Trial Update: A Study to Evaluate Fasting/Postprandial Serum Apolipoprotein B-48 (ApoB-48) Levels in Diabetic Participants With Normal to Moderately High Low Density Lipoprotein-C (LDL-C) Levels (MK-0653A-259 AM1) [NA]
This completed clinical trial evaluated fasting and postprandial ApoB-48 levels in diabetic participants with normal to moderately high LDL-…
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CLINICAL_TRIALS trial_result · 2013-04-05Clinical Trial Update: Safety and Efficacy Study of ISIS 301012 (Mipomersen) Administration in High Risk Statin Intolerant Subjects [Phase 2]
Phase 2 safety and efficacy results for mipomersen in high-risk statin-intolerant patients. Results were posted in 2013.
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CLINICAL_TRIALS trial_result · 2013-04-02Clinical Trial Update: Study of 3,5-Diiodothyropropionic Acid (DITPA) in Hypercholesterolemic Patients [Phase 1, Phase 2]
A Phase 1/Phase 2 study of the experimental compound DITPA was terminated in adults with hypercholesterolemia.
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CLINICAL_TRIALS trial_result · 2013-03-21Clinical Trial Update: Safety and Efficacy of Mipomersen in Patients With Severe Hypercholesterolemia on a Maximally Tolerated Lipid-Lowering Regimen and Who Are Not on Apheresis [Phase 3]
Phase 3 trial evaluating the safety and efficacy of mipomersen added to maximally tolerated lipid-lowering therapy in adults with severe hyp…
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CLINICAL_TRIALS trial_result · 2013-03-21Clinical Trial Update: Study to Assess the Safety and Efficacy of ISIS 301012 (Mipomersen) in Homozygous Familial Hypercholesterolemia [Phase 3]
Phase 3 study evaluating mipomersen (ISIS 301012) for homozygous familial hypercholesterolemia has completed with results posted in 2013.
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CLINICAL_TRIALS trial_result · 2013-03-20Clinical Trial Update: Safety and Efficacy of Mipomersen (ISIS 301012) As Add-on Therapy in High Risk Hypercholesterolemic Patients [Phase 3]
Phase 3 trial evaluating the safety and efficacy of mipomersen as add-on therapy in high-risk hypercholesterolemia patients. Results were po…
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CLINICAL_TRIALS trial_result · 2013-02-25Clinical Trial Update: Evaluate Safety and Efficacy of AEGR-733 and Atorvastatin vs Atorvastatin Monotherapy in Hypercholesterolemia [Phase 2]
Phase 2 trial comparing AEGR-733 plus atorvastatin to atorvastatin monotherapy in hypercholesterolemia; results posted on 2013-02-25.
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CLINICAL_TRIALS trial_result · 2013-02-21Clinical Trial Update: AEGR-733 and Atorvastatin 20 mg vs. Monotherapy in Moderate Hypercholesterolemia [Phase 2]
Phase 2 trial evaluating lomitapide (AEGR-733) with atorvastatin 20 mg versus atorvastatin monotherapy in adults with hypercholesterolemia; …
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CLINICAL_TRIALS trial_result · 2013-02-21Clinical Trial Update: Special Drug Use-Results Survey of Lipitor Tablets
A completed post-marketing survey evaluating real-world use and outcomes of Lipitor tablets (atorvastatin) in adults with hypercholesterolem…
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CLINICAL_TRIALS trial_result · 2013-02-20Clinical Trial Update: Effect of Ezetimibe on Platelet Aggregation and LDL Tendency to Peroxidation [Phase 4]
Phase 4 clinical trial update evaluating the effects of ezetimibe on platelet aggregation and LDL peroxidation tendency in hypercholesterole…
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CLINICAL_TRIALS trial_result · 2013-02-20Clinical Trial Update: The Effect of Serum LDL Lowering on Aspirin Resistance [NA]
This entry reports a completed clinical trial examining whether lowering serum LDL cholesterol affects aspirin resistance.
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CLINICAL_TRIALS trial_result · 2013-02-01Clinical Trial Update: Efficacy of High-oleic Canola and Flaxseed Oils for Hypercholesterolemia and Cardiovascular Disease Risk Factors [Phase 2]
Phase 2 clinical trial update assessing whether high-oleic canola oil and flaxseed oil reduce cholesterol and other cardiovascular risk fact…
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CLINICAL_TRIALS trial_result · 2013-01-15Clinical Trial Update: Centralised Pan-Algerian Survey on the Undertreatment of Hypercholesterolemia
A completed centralised Pan-Algerian survey evaluating undertreatment of hypercholesterolemia and related cardiovascular conditions.
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CLINICAL_TRIALS trial_result · 2013-01-10Clinical Trial Update: Effect of Niacin in the Lipoprotein (a) Concentration [Phase 4]
Phase 4 clinical trial evaluating the effect of niacin (nicotinic acid) on lipoprotein(a) concentration in individuals with hypercholesterol…
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CLINICAL_TRIALS trial_result · 2012-12-03Clinical Trial Update: Open Label Study To Evaluate The Long-Term Safety Profiles Of Caduet In Japanese Patients [Phase 4]
Open-label Phase 4 study assessing long-term safety of Caduet in Japanese patients completed; results posted in 2012.
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CLINICAL_TRIALS trial_result · 2012-11-27Clinical Trial Update: Cholesterol-lowering Effects of Lupin Protein [NA]
A completed clinical trial investigated the cholesterol-lowering effects of Lupin Protein in adults with hypercholesterolemia.
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CLINICAL_TRIALS trial_result · 2012-11-07Clinical Trial Update: Weight Loss Associated With the Consumption of Apple [NA]
A completed clinical trial investigating weight loss associated with apple consumption in individuals with hypercholesterolemia or overweigh…
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CLINICAL_TRIALS trial_result · 2012-10-30Clinical Trial Update: Effect of Tenofovir Disoproxil Fumarate on Lipid Levels in HIV Infected Adults on Stable Anti-HIV Drug Therapy [NA]
A completed clinical trial evaluated the effect of tenofovir disoproxil fumarate on lipid levels in HIV-infected adults on stable antiretrov…
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CLINICAL_TRIALS trial_result · 2012-10-25Clinical Trial Update: Plant Stanols and Gene Expression Profile [NA]
A completed clinical trial investigating plant stanols and their impact on gene expression in hypercholesterolemia patients.
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CLINICAL_TRIALS trial_result · 2012-10-12Clinical Trial Update: Analysis on the Risk of Cardiovascular Events in HIV- Infected Subjects Treated With LPV/r Based HAART Regimen vs. an EFV Based Regimen
A clinical trial analysis comparing the risk of cardiovascular events in HIV-infected individuals treated with lopinavir/ritonavir–based HAA…
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CLINICAL_TRIALS trial_result · 2012-10-12Clinical Trial Update: Trial to Evaluate Safety and Tolerability of ALN-PCS02 in Subjects With Elevated LDL-Cholesterol (LDL-C) [Phase 1]
Phase 1 trial evaluating the safety and tolerability of ALN-PCS02 in adults with elevated LDL-cholesterol has completed.
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CLINICAL_TRIALS trial_result · 2012-10-12Clinical Trial Update: The Rosuvastatin In TrAnsplant Recipients Study [Phase 4]
This document reports the completion of a Phase 4 clinical trial assessing rosuvastatin in transplant recipients with hypercholesterolemia.
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CLINICAL_TRIALS trial_result · 2012-10-05Clinical Trial Update: Intensive Glycemic Control and Skeletal Health Study [Phase 3]
Phase 3 clinical trial update on intensive glycemic control and skeletal health; the study is completed and results were posted in 2012.
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CLINICAL_TRIALS trial_result · 2012-09-17Clinical Trial Update: the Effect of a Red Rice Nutrition Supplement on Cholesterol Levels [Phase 4]
Phase 4 clinical trial assessing the effect of a red yeast rice (red rice) nutrition supplement on lipid parameters (total cholesterol, HDL,…