Hypercholesterolemia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2013-11-13Clinical Trial Update: Supplementation of Alpha-linolenic Acid (ALA)-Rich Oil in Humans [EARLY_Phase 1]
A completed early-stage 1 trial evaluated supplementation with alpha-linolenic acid-rich oil in adults who are overweight or have hyperchole…
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CLINICAL_TRIALS trial_result · 2013-11-13Clinical Trial Update: A Study to Evaluate the Efficacy and Safety of Rosuvastatin in Hypercholesterolemia. [NA]
A clinical trial update evaluating the efficacy and safety of rosuvastatin for hypercholesterolemia. The document provides no trial results …
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CLINICAL_TRIALS trial_result · 2013-10-29Clinical Trial Update: Intervention With Lupin Protein-enriched Foods in Hypercholesterolemic Subjects [NA]
A University of Jena–sponsored clinical trial evaluating lupin protein-enriched foods in adults with hypercholesterolemia has completed. The…
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CLINICAL_TRIALS trial_result · 2013-10-14Clinical Trial Update: Comparison of Pitavastatin With Atorvastatin in Increasing High Density Lipoprotein - Cholesterol (HDL-C) and Adiponectin in Patients With Dyslipidemia and Coronary Artery Disease (CAD) [Phase 4]
A Phase 4 study compares pitavastatin with atorvastatin to increase HDL-C and adiponectin in patients with dyslipidemia and coronary artery …
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CLINICAL_TRIALS trial_result · 2013-09-25Clinical Trial Update: Role of Milk Fat Globule Membranes in Dairy Foods: Health Effects in Humans [NA]
A completed clinical trial led by Uppsala University evaluated the health effects of milk fat globule membranes in dairy foods on people wit…
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CLINICAL_TRIALS trial_result · 2013-09-10Clinical Trial Update: Effect of a Community-based Nursing Intervention on Mortality in Chronically Ill Older Adults [NA]
Clinical trial update evaluating a community-based nursing intervention on mortality in chronically ill older adults. The study includes par…
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CLINICAL_TRIALS trial_result · 2013-08-27Clinical Trial Update: Flaxseed Compared With Placebo in Patients With Hypercholesterolemia [Phase 3]
Phase 3 trial comparing flaxseed with placebo in patients with familial or severe hypercholesterolemia has completed.
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CLINICAL_TRIALS trial_result · 2013-08-21Clinical Trial Update: Effects of The Effects of Dietary Oils on Fasting Lipoprotein Lipids [NA]
A completed clinical trial assessed the impact of dietary oils on fasting lipoprotein lipids in individuals with hypercholesterolemia.
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CLINICAL_TRIALS trial_result · 2013-08-19Clinical Trial Update: Health Benefits of Whole Grain Oats in Population at Risk of Cardio-metabolic Disease [NA]
Completed clinical trial evaluating health benefits of whole grain oats in individuals at risk of cardiovascular disease and hypercholestero…
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CLINICAL_TRIALS trial_result · 2013-08-19Clinical Trial Update: Pharmacokinetic of Alirocumab SAR236553 (REGN727) Administered Subcutaneously at 3 Different Injection Sites in Healthy Subjects [Phase 1]
A Phase 1 pharmacokinetic study evaluating alirocumab (SAR236553/REGN727) given subcutaneously at three different injection sites in healthy…
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CLINICAL_TRIALS trial_result · 2013-08-05Clinical Trial Update: A Study to Evaluate the Effectiveness of Ezetimibe/Atorvastatin 10 mg/20 mg Combination Tablet Compared to Marketed Ezetimibe 10 mg and Atorvastatin 20 mg Tablets in Participants With High Cholesterol (MK-0653C-185 AM1) [Phase 3]
Phase 3 trial evaluating a fixed-dose combination of ezetimibe/atorvastatin versus separate ezetimibe and atorvastatin in patients with high…
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CLINICAL_TRIALS trial_result · 2013-07-10Clinical Trial Update: A Study to Evaluate the Effectiveness of Ezetimibe/Atorvastatin 10 mg/40 mg Combination Tablet Compared to Marketed Ezetimibe 10 mg and Atorvastatin 40 mg Tablets in Participants With High Cholesterol (MK-0653C-190 AM1) [Phase 3]
A Phase 3 trial evaluating the effectiveness of ezetimibe/atorvastatin 10 mg/40 mg combination versus separate ezetimibe 10 mg and atorvasta…
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CLINICAL_TRIALS trial_result · 2013-07-03Clinical Trial Update: Comparison of the Effect of Vytorin 10/80 Tablet Split Into 4 and Simvastatin 20 Milligrams on Low-density Lipoprotein (LDL) Cholesterol [Phase 4]
This Phase 4 trial compared splitting Vytorin 10/80 into four tablets versus taking Simvastatin 20 mg for lowering LDL cholesterol in people…
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CLINICAL_TRIALS trial_result · 2013-06-28Clinical Trial Update: Injection Site Tolerability, Safety, Pharmacokinetics, Pharmacodynamics in Different Single-Dose Treatments of Alirocumab SAR236553 (REGN727) in Healthy Subjects [Phase 1]
Phase 1 trial update evaluating injection site tolerability, safety, pharmacokinetics and pharmacodynamics of different single-dose regimens…
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CLINICAL_TRIALS trial_result · 2013-06-28Clinical Trial Update: Pharmacokinetic and Tolerability of Alirocumab SAR236553 (REGN727) in Patients With Hepatic Impairment and in Healthy Subjects [Phase 1]
Phase 1 pharmacokinetic and tolerability study of alirocumab in patients with hepatic impairment and in healthy subjects has completed. The …
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CLINICAL_TRIALS trial_result · 2013-06-28Clinical Trial Update: Injection Site Tolerability, Safety, Pharmacokinetics and Pharmacodynamics Study After a Single Dose Subcutaneous Treatment of Alirocumab SAR236553 (REGN727) [Phase 1]
Phase 1 study evaluating injection site tolerability, safety, and pharmacokinetics/pharmacodynamics after a single subcutaneous dose of alir…
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CLINICAL_TRIALS trial_result · 2013-06-28Clinical Trial Update: Study of the Tolerability, Safety, Pharmacokinetics and Pharmacodynamics of Alirocumab SAR236553 (REGN727) [Phase 1]
A Phase 1 study assessed tolerability, safety, pharmacokinetics and pharmacodynamics of Alirocumab (REGN727/SAR236553) in hypercholesterolem…
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CLINICAL_TRIALS trial_result · 2013-06-20Clinical Trial Update: Lipid-lowering Effect of Plant Stanol Yogurt [NA]
Completed clinical trial evaluating the lipid-lowering effect of plant stanol yogurt sponsored by Raisio Group.
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CLINICAL_TRIALS trial_result · 2013-06-14Clinical Trial Update: Evaluation of LDL Cholesterol in Patients Switched From 10 to 5 Milligrams of Zetia (Ezetimibe) [NA]
A completed clinical trial evaluated LDL cholesterol changes when patients with hypercholesterolemia were switched from 10 mg to 5 mg of Zet…
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CLINICAL_TRIALS trial_result · 2013-05-30Clinical Trial Update: Pediatric Study to Evaluate the Efficacy and Safety of Ezetimibe Monotherapy in Children With Primary Hypercholesterolemia (P05522) [Phase 3]
Phase 3 pediatric trial evaluating ezetimibe monotherapy for primary hypercholesterolemia has completed. Results were posted in 2013.
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CLINICAL_TRIALS trial_result · 2013-05-30Clinical Trial Update: Amlodipine/Atorvastatin (Caduet®) Drug Use Investigation (Regulatory Post Marketing Commitment Plan)
Clinical trial update for Amlodipine/Atorvastatin (Caduet) under regulatory post-marketing commitments; study completed with results posted …
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CLINICAL_TRIALS trial_result · 2013-05-20Clinical Trial Update: Low Carbohydrate Portfolio or "Eco-Atkins" Diet [Phase 2]
Phase 2 trial evaluating a low-carbohydrate diet called Eco-Atkins for hypercholesterolemia and cardiovascular disease has completed.
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CLINICAL_TRIALS trial_result · 2013-05-17Clinical Trial Update: Supplementation of Land-based Stearidonic Acid (SDA)-Rich Oils in Humans [EARLY_Phase 1]
An early-phase 1 trial evaluated supplementation with land-based stearidonic acid (SDA)-rich oils in adults with hypercholesterolemia or ove…
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CLINICAL_TRIALS trial_result · 2013-05-14Clinical Trial Update: Gut Flora and Lipid Metabolism [NA]
Clinical trial examining the relationship between gut microbiota and lipid metabolism in hypercholesterolemia has completed.
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CLINICAL_TRIALS trial_result · 2013-05-08Clinical Trial Update: Probiotic BIO-25 as a Supplement to Statins for the Treatment of Hypercholesterolemia [Phase 4]
Phase 4 clinical trial update for BIO-25 probiotic as a supplement to statins in hypercholesterolemia; current status is unknown.