Hypercholesterolemia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2014-07-03Clinical Trial Update: The Effect of Atorvastatin on Endothelial Cell Dysfunction in Chronic Kidney Disease [Phase 4]
A Phase 4 trial evaluating atorvastatin for endothelial cell dysfunction in chronic kidney disease with hypercholesterolemia was terminated.…
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CLINICAL_TRIALS trial_result · 2014-06-26Clinical Trial Update: Efficacy of a One-a-Day L. Reuteri NCIMB 30242 Probiotic Supplement Capsule [Phase 2]
A Phase 2 study assessed the efficacy of a daily Lactobacillus reuteri NCIMB 30242 probiotic capsule in adults with hypercholesterolemia; th…
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CLINICAL_TRIALS trial_result · 2014-06-11Clinical Trial Update: Efficacy and Safety of Fluvastatin Sodium Extended Release Tablets 80 mg Once Daily in Chinese Patients With Primary Hypercholesterolemia or Mixed Dyslipidemia [Phase 4]
Phase 4 trial evaluating the efficacy and safety of fluvastatin sodium extended-release 80 mg once daily in Chinese patients with primary hy…
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CLINICAL_TRIALS trial_result · 2014-05-20Clinical Trial Update: The Effect of a Red Rice and Olive Extract Nutrition Supplement on Cholesterol Levels in Patients With Metabolic Syndrome [Phase 4]
Phase 4 trial completed evaluating whether a red rice and olive extract nutrition supplement lowers cholesterol in patients with metabolic s…
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CLINICAL_TRIALS trial_result · 2014-05-16Clinical Trial Update: Influence of OATP1B1 and BRCP Genotype on Rosuvastatin PK, PD and Lipidomics in Hyperlipidemic Patients [Phase 4]
Phase 4 study assessing how OATP1B1 and BRCP genotypes influence rosuvastatin pharmacokinetics, pharmacodynamics, and lipidomics in hypercho…
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CLINICAL_TRIALS trial_result · 2014-05-15Clinical Trial Update: Metformin in Preventing Androgen Deprivation Therapy Induced Insulin Resistance and Metabolic Syndrome [Phase 2]
Phase 2 trial evaluating metformin to prevent androgen deprivation therapy-induced insulin resistance and metabolic syndrome. The study stat…
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CLINICAL_TRIALS trial_result · 2014-04-25Clinical Trial Update: Niacin (+) Laropiprant (TREDAPTIVE) Re-examination Study (MK-0524A-119)
The Niacin/laropiprant re-examination study (TREDAPTIVE) for hypercholesterolemia and mixed dyslipidemia was terminated, with results posted…
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CLINICAL_TRIALS trial_result · 2014-04-09Clinical Trial Update: Investigation of the Effect of Dietary Nitrate Treatment on Endothelial Function and Platelet Reactivity in Hypercholesterolemics. [Phase 1]
A Phase 1 clinical trial assessing whether dietary nitrate improves endothelial function and modulates platelet reactivity in adults with hy…
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CLINICAL_TRIALS trial_result · 2014-04-02Clinical Trial Update: TACTICS (Targeting Adherence to Cholesterol-lowering Therapy to Improve Control Study) [NA]
This clinical trial update indicates that the TACTICS study on adherence to cholesterol-lowering therapy for hypercholesterolemia has comple…
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CLINICAL_TRIALS trial_result · 2014-03-19Clinical Trial Update: A Multicenter, Active and Placebo-controlled Study of Enteric Coated Sevelamer in Patients With Mild to Moderate Hypercholesteremia [Phase 2]
A Phase 2 multicenter trial evaluating enteric-coated sevelamer in patients with mild to moderate hypercholesterolemia has completed.
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CLINICAL_TRIALS trial_result · 2014-03-19Clinical Trial Update: Blood Lipid-lowering Effect of Brown Alga Ecklonia Cava [Phase 2, Phase 3]
Phase 2/3 clinical trial evaluating the blood lipid-lowering effect of Ecklonia cava extract in adults with hypercholesterolemia has complet…
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CLINICAL_TRIALS trial_result · 2014-03-17Clinical Trial Update: Alternative Options to Minimize Niacin-Induced Flushing [NA]
A completed clinical trial evaluated alternative strategies to minimize niacin-induced flushing in people with high cholesterol; results wer…
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CLINICAL_TRIALS trial_result · 2014-03-14Clinical Trial Update: Efficacy and Safety of Extended Release (ER) Niacin/Laropiprant When Added to Ongoing Lipid-Modifying Therapy in Patients With High Cholesterol or Abnormal Lipid Levels (MK-0524A-133) [Phase 3]
Phase 3 trial evaluating MK-0524A (extended-release niacin/laropiprant) added to ongoing lipid-modifying therapy in patients with primary hy…
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CLINICAL_TRIALS trial_result · 2014-03-13Clinical Trial Update: Phytosterol Supplementation and Cardiovascular Risk [NA]
This clinical trial update reports the completion of a study assessing phytosterol supplementation for cardiovascular risk in individuals wi…
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CLINICAL_TRIALS trial_result · 2014-03-11Clinical Trial Update: Effect of Beta-Glucan on Cholesterol Lowering [NA]
A completed clinical trial evaluated beta-glucan for cholesterol lowering in adults with hypercholesterolemia. Results were posted on 2014-0…
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CLINICAL_TRIALS trial_result · 2014-03-05Clinical Trial Update: Long Term Efficacy and Tolerability of a Nutraceutical Combination (Red Yeast Rice, Policosanols and Berberine) in Low-moderate Risk Hypercholesterolemic Patients: a Double-blind, Placebo Controlled Study [Phase 4]
This Phase 4 trial evaluated the long-term efficacy and tolerability of a nutraceutical combination of red yeast rice, policosanols, and ber…
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CLINICAL_TRIALS trial_result · 2014-03-04Clinical Trial Update: The Safety & Efficacy of Combination BMS-201038 (AEGR-733) & Ezetimibe vs. Monotherapy in Moderate Hypercholesterolemia [Phase 2]
Phase 2 trial results comparing the safety and efficacy of combining AEGR-733 (BMS-201038) with ezetimibe versus ezetimibe monotherapy in mo…
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CLINICAL_TRIALS trial_result · 2014-02-12Clinical Trial Update: MK0653C in High Cardiovascular Risk Patients With High Cholesterol (Switch Study)(MK-0653C-162) [Phase 3]
A Phase 3 trial evaluating MK0653C in high cardiovascular risk patients with high cholesterol has completed; results were posted in 2014.
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CLINICAL_TRIALS trial_result · 2014-01-29Clinical Trial Update: Cholesterol Lowering Treatment With Psyllium Husks and Isolated Soy Protein in Hypercholesterolemia [Phase 4]
Phase 4 clinical trial assessing the cholesterol-lowering effects of psyllium husks in combination with isolated soy protein in hypercholest…
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CLINICAL_TRIALS trial_result · 2013-12-31Clinical Trial Update: Cardiovascular Risk Factors, Body Composition, Fitness Levels And Quality Of Life In Overweight And Obese 8-17 Year Olds [NA]
Completed clinical trial update examining cardiovascular risk factors, body composition, fitness levels, and quality of life in overweight a…
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CLINICAL_TRIALS trial_result · 2013-12-17Clinical Trial Update: The Efficacy and Safety of Atorva® 20mg Versus Lipitor® 20mg [Phase 4]
Phase 4 trial comparing Atorva 20 mg with Lipitor 20 mg in hypercholesterolemia to evaluate relative efficacy and safety.
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CLINICAL_TRIALS trial_result · 2013-12-17Clinical Trial Update: The Efficacy and Tolerability of Two Formulations of Atorvastatin In Korean Adult With Hypercholesterolemia [Phase 4]
Phase 4 trial comparing two formulations of atorvastatin in Korean adults with hypercholesterolemia showed data on efficacy and tolerability…
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CLINICAL_TRIALS trial_result · 2013-12-13Clinical Trial Update: Metabolism And Health Effects Of Citrus Limonoids in Hypercholesterolemic Humans [NA]
A completed clinical trial investigated the metabolism and health effects of citrus limonoids in adults with hypercholesterolemia.
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CLINICAL_TRIALS trial_result · 2013-12-10Clinical Trial Update: Safety, Tolerability, PK and PD of LGT209 in Healthy Volunteers and Patients With Hypercholesterolemia [Phase 1]
Phase 1 trial evaluating safety, tolerability, pharmacokinetics and pharmacodynamics of LGT209 in healthy volunteers and patients with hyper…
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CLINICAL_TRIALS trial_result · 2013-11-25Clinical Trial Update: Study of Changes in Total Cholesterol Levels as a Function of Consuming a Supplement Designed to Improve Cardiovascular Health [NA]
This clinical trial update investigates whether a cardiovascular-health supplement changes total cholesterol levels. Details about the suppl…