Hypercholesterolemia

• CLINICAL_TRIALS trial_result · 2025-12-23
  Clinical Trial Update: Effects of RDX-002 on Postprandial Triglycerides in Patients Discontinuing GLP-1 Agonists [Phase 2]

  Phase 2 trial evaluating RDX-002's effect on postprandial triglycerides in patients discontinuing GLP-1 agonists; study completed.

• CLINICAL_TRIALS trial_result · 2025-12-19
  Clinical Trial Update: A Study of SAL003 in Participants With Hypercholesterolemia and Mixed Dyslipidemia [Phase 3]

  Phase 3 clinical trial SAL003 in hypercholesterolemia and mixed dyslipidemia has completed enrollment and status is updated.

• CLINICAL_TRIALS trial_result · 2025-12-16
  Clinical Trial Update: Statin Reminders for Improving Prescribing in Primary Care [NA]

  A completed clinical trial evaluating the impact of statin reminders on prescribing in primary care for hypercholesterolemia.

• CLINICAL_TRIALS trial_result · 2025-12-12
  Clinical Trial Update: A Phase II Study to Evaluate the Safety and Efficacy of SAL003 Combined With Atorvastatin in Hypercholesterolemia and Mixed Dyslipidemia [Phase 2]

  This update reports the completion of a Phase II study evaluating the safety and efficacy of SAL003 in combination with atorvastatin for hyp…

• CLINICAL_TRIALS trial_result · 2025-12-11
  Clinical Trial Update: A Phase III Confirmatory Study of K-877 (Pemafibrate) in Patients With Hypercholesterolemia and Statin Intolerance [Phase 3]

  This Clinical Trial Update notes a Phase III confirmatory study of pemafibrate (K-877) for hypercholesterolemia in statin-intolerant patient…

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• CLINICAL_TRIALS trial_result · 2025-12-08
  Clinical Trial Update: A Study to Investigate the Effectiveness and Safety of Bempedoic Acid in Patients With Primary Hypercholesterolemia or Mixed Dyslipidemia in Taiwan [Phase 4]

  This Phase 4 clinical trial evaluating the effectiveness and safety of bempedoic acid in adults with primary hypercholesterolemia or mixed d…

• CLINICAL_TRIALS trial_result · 2025-11-28
  Clinical Trial Update: A Multicenter, Randomized, Double-blind, Placebo-controlled Phase III Clinical Study to Evaluate the Safety and Efficacy of SAL003 in Combination With Statin Therapy in Patients With Hypercholesterolemia and Mixed Dyslipidemia [Phase 3]

  A multicenter, randomized Phase III trial evaluated SAL003 in combination with statin therapy for hyperlipidemia and mixed dyslipidemia and …

• CLINICAL_TRIALS trial_result · 2025-11-25
  Clinical Trial Update: A Study to Evaluate the Efficacy and Safety of Co-administrated BR1018B and BR1018C [Phase 3]

  The document reports the completion of a Phase 3 clinical trial evaluating the efficacy and safety of co-administered BR1018B and BR1018C. T…

• CLINICAL_TRIALS trial_result · 2025-11-17
  Clinical Trial Update: Effect of Sunflower Seed Consumption on Blood Cholesterol Levels in Adults [NA]

  A completed clinical trial examined whether daily sunflower seed consumption affects blood cholesterol levels in adults with hypercholestero…

• CLINICAL_TRIALS trial_result · 2025-10-08
  Clinical Trial Update: Study of Obicetrapib & Ezetimibe Fixed Dose Combination on Top of Maximum Tolerated Lipid-Modifying Therapies [Phase 3]

  Phase 3 study evaluating a fixed-dose combination of obicetrapib and ezetimibe added to existing lipid-modifying therapy has completed. Resu…

• CLINICAL_TRIALS trial_result · 2025-10-07
  Clinical Trial Update: Open-label Extension Study of Enlicitide Decanoate (MK-0616/Enlicitide Oral PCSK9 Inhibitor) in Adults With Hypercholesterolemia (MK-0616-019) CORALreef Extension [Phase 3]

  Open-label extension of a Phase 3 trial evaluating Enlicitide Decanoate (MK-0616) for hypercholesterolemia, with ACTIVE_NOT_RECRUITING statu…

• CLINICAL_TRIALS trial_result · 2025-10-01
  Clinical Trial Update: A Study to Evaluate the Safety and Pharmacokinetics of AD-228A Compared to Coadministration of AD-2281 and AD-2282 [Phase 1]

  A Phase 1 clinical trial update reports on safety and pharmacokinetics evaluation of AD-228A versus coadministration of AD-2281 and AD-2282 …

• CLINICAL_TRIALS trial_result · 2025-09-22
  Clinical Trial Update: A Study to Evaluate the Efficacy and the Safety of Single Pill Combination (SPC) Ezetimibe/Rosuvastatin in Chinese Adult Patients With Primary Hypercholesterolemia Not Adequately Controlled on Statin Therapy [Phase 3]

  Phase 3 trial evaluating the efficacy and safety of a single-pill combination ezetimibe/rosuvastatin in Chinese adults with primary hypercho…

• CLINICAL_TRIALS trial_result · 2025-09-19
  Clinical Trial Update: Randomized Study to Evaluate the Effect of Obicetrapib on Top of Maximum Tolerated Lipid-Modifying Therapies [Phase 3]

  Phase 3 randomized study evaluating obicetrapib added to maximum tolerated lipid-modifying therapies has completed, with results posted.

• CLINICAL_TRIALS trial_result · 2025-09-12
  Clinical Trial Update: An OS to Evaluate the Safety & Efficacy of Fixed Dose Combination Therapy With Atorvastatin and Ezetimibe

  This clinical trial update reports on a completed study evaluating the safety and efficacy of a fixed-dose combination of atorvastatin and e…

• CLINICAL_TRIALS trial_result · 2025-09-12
  Clinical Trial Update: Bioequivalence Study of Bempedoic Acid 180 mg Film Coated Tablet and Nilemdo® (Bempedoic Acid) 180 mg Film-coated Tablets [Phase 1]

  Phase 1 bioequivalence study comparing bempedoic acid 180 mg film-coated tablets with Nilemdo 180 mg film-coated tablets has completed.

• CLINICAL_TRIALS trial_result · 2025-09-10
  Clinical Trial Update: A Study of Enlicitide Decanoate (MK-0616 Oral PCSK9 Inhibitor) in Adults With Hypercholesterolemia (MK-0616-013) CORALreef Lipids [Phase 3]

  Phase 3 trial update for Enlicitide Decanoate (MK-0616), an oral PCSK9 inhibitor, in adults with hypercholesterolemia, including familial hy…

• CLINICAL_TRIALS trial_result · 2025-08-13
  Clinical Trial Update: Efficacy and Safety of Inclisiran as Monotherapy in Patients With Primary Hypercholesterolemia Not Receiving Lipid-lowering Therapy. [Phase 3]

  Phase 3 results assess the efficacy and safety of Inclisiran as monotherapy in patients with primary hypercholesterolemia not receiving lipi…

• CLINICAL_TRIALS trial_result · 2025-08-08
  Clinical Trial Update: A Clinical Study in Children With Heterozygous Familial Hypercholesterolemia (HeFH) Aged 6 to 17 Treated Once Daily With Bempedoic Acid Oral Dosing (CLEAR Path 1) [Phase 2]

  A Phase 2 pediatric trial evaluating once-daily oral bempedoic acid in children aged 6 to 17 with heterozygous familial hypercholesterolemia…

• CLINICAL_TRIALS trial_result · 2025-07-31
  Clinical Trial Update: The Benefits of the Measureof Epicardial Adipose Tissue During Coronary Calcium Assessment of the Refine Cardiovascular Risk Assessment at Reunion Island.

  This completed clinical study evaluated whether measuring epicardial adipose tissue alongside coronary calcium scoring improves refinement o…

• CLINICAL_TRIALS trial_result · 2025-07-29
  Clinical Trial Update: Efficacy and Safety of Atorvastatin and Ezetimibe (10/10mg) Fixed Dose Combination Versus Atorvastatin (20mg) Monotherapy in Bangladeshi Population [Phase 4]

  Phase 4 clinical trial in Bangladesh comparing atorvastatin/ezetimibe fixed-dose combination (10/10 mg) to atorvastatin 20 mg monotherapy fo…

• CLINICAL_TRIALS trial_result · 2025-07-28
  Clinical Trial Update: Effects of a Chilean Diet Supplemented With Gevuina Avellana on Lipid Profile in Humans With Hypercholesterolemia [NA]

  A clinical trial from Universidad de Concepcion evaluated the effect of a Chilean diet supplemented with Gevuina Avellana on lipid profiles …

• CLINICAL_TRIALS trial_result · 2025-07-16
  Clinical Trial Update: Treatment With Rosuvastatin Versus Switching PI (Protease Inhibitor) in Patients HIV With High Cholesterol Levels [Phase 4]

  Phase 4 trial comparing rosuvastatin to switching protease inhibitors in people with HIV and high cholesterol; results have been posted.

• CLINICAL_TRIALS trial_result · 2025-06-24
  Clinical Trial Update: Study of SHR-1209 Administered by Single-site or Multiple-site Subcutaneous Injections in Healthy Volunteers [Phase 1]

  Phase 1 trial evaluating safety and pharmacokinetics of SHR-1209 administered by single-site or multi-site subcutaneous injections in health…

• CLINICAL_TRIALS trial_result · 2025-06-12
  Clinical Trial Update: To Evaluate the Safety and Pharmacokinetic Characteristics of AJU-C711 in Healthy Adults [Phase 1]

  A Phase 1 clinical trial update evaluating the safety and pharmacokinetic characteristics of AJU-C711 in healthy adults, with hypercholester…