Hypercholesterolemia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2015-08-31Clinical Trial Update: Study of the Efficacy and Safety of Alirocumab (REGN727/SAR236553) in Combination With Other Lipid-modifying Treatment (LMT) (ODYSSEY OPTIONS I) [Phase 3]
Phase 3 trial results for alirocumab in combination with other lipid-modifying therapy in hypercholesterolemia; the study completed with res…
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CLINICAL_TRIALS trial_result · 2015-08-28Clinical Trial Update: Study of Alirocumab (REGN727/SAR236553) in Patients With Primary Hypercholesterolemia and Moderate, High, or Very High Cardiovascular (CV) Risk, Who Are Intolerant to Statins (ODYSSEY ALTERNATIVE) [Phase 3]
Phase 3 trial results for alirocumab in statin-intolerant patients with primary hypercholesterolemia and high cardiovascular risk have been …
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CLINICAL_TRIALS trial_result · 2015-08-28Clinical Trial Update: One-Day Acceptance and Commitment Training Intervention in Primary Care Patients [NA]
A completed clinical trial evaluated a one-day Acceptance and Commitment Training intervention for primary care patients. Results were poste…
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CLINICAL_TRIALS trial_result · 2015-08-14Clinical Trial Update: Effect of Statin Treatment on Urinary AQP2 (uAQP2/01)
A completed clinical trial investigates the effect of statin treatment on urinary aquaporin-2 (uAQP2).
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CLINICAL_TRIALS trial_result · 2015-08-03Clinical Trial Update: Using Nudges to Implement Comparative Effectiveness
A completed study from NYU Langone Health investigates how behavioral nudges can facilitate the implementation of comparative effectiveness …
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CLINICAL_TRIALS trial_result · 2015-07-27Clinical Trial Update: Lipid Efficacy/Tolerability Study (0524A-020) [Phase 3]
A Phase 3 trial evaluating lipid efficacy and tolerability (0524A-020) has completed. The study targeted primary hypercholesterolemia and mi…
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CLINICAL_TRIALS trial_result · 2015-07-15Clinical Trial Update: Retinoic Acid Supplementation and Subjects With Hypercholesterolemia [EARLY_Phase 1]
An early-phase 1 trial sponsored by Sun Yat-sen University evaluated retinoic acid supplementation in people with hypercholesterolemia and t…
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CLINICAL_TRIALS trial_result · 2015-07-01Clinical Trial Update: Effectiveness of Nigella Sativa (Kalonji) Seed in Dyslipidemia [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluated the effectiveness of Nigella sativa seed for dyslipidemia; the study, conducted by Aga Khan University,…
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CLINICAL_TRIALS trial_result · 2015-06-18Clinical Trial Update: The Effect of Shuhua Milk Fortified With Plant Sterol Esters on Serum Cholesterol in Human [NA]
Completed clinical trial evaluating whether Shuhua Milk fortified with plant sterol esters lowers serum cholesterol in adults with hyperchol…
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CLINICAL_TRIALS trial_result · 2015-06-02Clinical Trial Update: Comparison of the Efficacy of Plant Sterol-Enriched Soymilk Versus Plain Soymilk in Volunteers With High LDL-Cholesterol [NA]
A completed clinical trial sponsored by Chiang Mai University compared plant sterol-enriched soymilk with plain soymilk in adults with high …
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CLINICAL_TRIALS trial_result · 2015-05-21Clinical Trial Update: Statins in Children With Type 1 Diabetes and Hypercholesterolemia [Phase 3]
Phase 3 trial update on statin use in children with Type 1 diabetes and hypercholesterolemia; results completed and posted in 2015.
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CLINICAL_TRIALS trial_result · 2015-05-15Clinical Trial Update: Efficacy/Safety of DP-R207 Tablet Versus CRESTOR Tablet in Patients With Primary Hypercholesterolemia [Phase 3]
Phase 3 trial comparing DP-R207 tablet to CRESTOR tablet in adults with primary hypercholesterolemia to assess efficacy and safety; the stud…
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CLINICAL_TRIALS trial_result · 2015-05-07Clinical Trial Update: Pharmacokinetic And Pharmacodynamic Study Of A Single-Dose Of PF-04950615 (RN316) In Combination With Atorvastatin [Phase 1]
A Phase 1 pharmacokinetic and pharmacodynamic study evaluated a single dose of PF-04950615 (RN316) in combination with atorvastatin in indiv…
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CLINICAL_TRIALS trial_result · 2015-04-22Clinical Trial Update: Carotid B-Mode Ultrasound Study to Compare Anti-Atherosclerotic Effect of Torcetrpib/Atorvastatin to Atorvastatin Alone. [Phase 3]
Phase 3 study comparing the anti-atherosclerotic effect of torcetrapib added to atorvastatin versus atorvastatin alone has completed.
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CLINICAL_TRIALS trial_result · 2015-04-22Clinical Trial Update: Nutraceutical Combination in Patients With Low-grade Systemic Inflammation [Phase 4]
Phase 4 clinical trial update on a nutraceutical combination in patients with low-grade systemic inflammation, including those with atherosc…
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CLINICAL_TRIALS trial_result · 2015-04-08Clinical Trial Update: Effects of Vitamin D on Lipids [NA]
This document provides an update on a completed clinical trial evaluating whether vitamin D supplementation affects lipid levels in people w…
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CLINICAL_TRIALS trial_result · 2015-04-07Clinical Trial Update: Effects of Dietary Antioxidants to Prevent Cardiovascular Disease [Phase 2]
Phase 2 clinical trial update examining whether dietary antioxidants can prevent cardiovascular disease; the study has completed, and includ…
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CLINICAL_TRIALS trial_result · 2015-04-03Clinical Trial Update: A Study to Determine the Effect of WelChol Tablets on Cholesterol in Patients Who Have Been Taking Atorvastatin for at Least 4 Weeks. [Phase 4]
Phase 4 trial investigating the effect of WelChol tablets (colesevelam) on cholesterol in patients already taking atorvastatin for at least …
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CLINICAL_TRIALS trial_result · 2015-04-03Clinical Trial Update: A Study to Determine the Effect of WelChol Tablets on Cholesterol in Patients Who Have Been Taking Simvastatin for at Least 4 Weeks. [Phase 4]
This Phase 4 clinical trial evaluated WelChol (cholestyramine) tablets for lowering cholesterol in patients who had been taking simvastatin …
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CLINICAL_TRIALS trial_result · 2015-04-03Clinical Trial Update: Study to Compare Welchol and TriCor to TriCor Alone in Patients With High Cholesterol [Phase 4]
A Phase 4 study comparing Welchol (colesevelam) plus TriCor (fenofibrate) to TriCor alone in patients with hypercholesterolemia and hyperlip…
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CLINICAL_TRIALS trial_result · 2015-04-03Clinical Trial Update: A Study to Determine the Effect of WelChol Tablets on Cholesterol in Patients Who Have Been Taking Pravastatin for at Least 4 Weeks. [Phase 4]
Phase 4 trial evaluating the effect of WelChol (colesevelam) on cholesterol levels in patients who have been taking pravastatin for at least…
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CLINICAL_TRIALS trial_result · 2015-04-01Clinical Trial Update: Plaque REgression With Cholesterol Absorption Inhibitor or Synthesis Inhibitor Evaluated by IntraVascular UltraSound [Phase 4]
A Phase 4 clinical trial evaluated plaque regression using either a cholesterol absorption inhibitor or a cholesterol synthesis inhibitor, a…
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CLINICAL_TRIALS trial_result · 2015-03-17Clinical Trial Update: LIpid Lowering With Highly Potent Statins in Hyperlipidaemia With Type 2 Diabetes patiENts [NA]
A completed clinical trial evaluating lipid-lowering with highly potent statins in patients with hypercholesterolemia and type 2 diabetes, w…
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CLINICAL_TRIALS trial_result · 2015-03-17Clinical Trial Update: A Human Trial to Assess the Low Density Lipoprotein Cholesterol (LDL-C) Lowering Effect of Soy [NA]
A clinical trial evaluated whether soy can lower LDL cholesterol in individuals with hypercholesterolemia and cardiovascular disease; the st…
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CLINICAL_TRIALS trial_result · 2015-03-09Clinical Trial Update: Effect of Apples on cardioVascular Risk And Gut Health [NA]
A completed clinical trial from the University of Reading examined whether apple consumption affects cardiovascular risk markers and gut hea…