Hypercholesterolemia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2015-12-23Clinical Trial Update: Study of Children's Activity and Nutrition (SCAN)
The SCAN trial (Study of Children’s Activity and Nutrition) sponsored by Augusta University has completed, investigating cardiovascular risk…
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CLINICAL_TRIALS trial_result · 2015-12-22Clinical Trial Update: Long-term Safety and Tolerability of Alirocumab (SAR236553/REGN727) Versus Placebo on Top of Lipid-Modifying Therapy in High Cardiovascular Risk Patients With Hypercholesterolemia (ODYSSEY Long Term) [Phase 3]
Phase 3 long-term safety and tolerability results for alirocumab (Praluent) versus placebo on background lipid-lowering therapy in high-risk…
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CLINICAL_TRIALS trial_result · 2015-12-22Clinical Trial Update: The Effect of Synching Prescription Refills on Adherence [NA]
The University of Pennsylvania clinical trial evaluated whether syncing prescription refills improves medication adherence in patients with …
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CLINICAL_TRIALS trial_result · 2015-12-21Clinical Trial Update: An Open-label Extension Study to Assess the Long-term Safety and Efficacy of ISIS 301012 (Mipomersen) in Patients With Familial Hypercholesterolemia or Severe-Hypercholesterolemia [Phase 3]
An open-label extension of a Phase 3 trial assessing the long-term safety and efficacy of mipomersen in patients with familial hypercholeste…
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CLINICAL_TRIALS trial_result · 2015-12-18Clinical Trial Update: Improving the Quality of Patient Care by Using a Clinical Expert System. [NA]
Completed trial evaluating a clinical expert system intended to improve patient care, with results posted.
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CLINICAL_TRIALS trial_result · 2015-12-17Clinical Trial Update: A Phase 1 Study of an Investigational Drug, ALN-PCSSC, in Subjects With Elevated Low Density Lipoprotein Cholesterol (LDL-C) [Phase 1]
Phase 1 clinical trial update on ALN-PCSSC in subjects with elevated LDL cholesterol (hypercholesterolemia); the study status is completed.
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CLINICAL_TRIALS trial_result · 2015-12-11Clinical Trial Update: Lipid-lowering Effect of Plant Stanol Ester Yoghurt Drinks [NA]
Completed clinical trial assessing the lipid-lowering effect of plant stanol ester yogurt drinks sponsored by Raisio Group.
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CLINICAL_TRIALS trial_result · 2015-11-24Clinical Trial Update: Medication Adherence With Polyglot Meducation [NA]
A completed clinical trial evaluated adherence to a polyglot medication regimen in patients with hypertension, diabetes mellitus, and hyperc…
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CLINICAL_TRIALS trial_result · 2015-11-06Clinical Trial Update: Efficacy and Safety of Alirocumab (SAR236553/REGN727) Versus Ezetimibe on Top of Statin in High Cardiovascular Risk Patients With Hypercholesterolemia (ODYSSEY COMBO II) [Phase 3]
Phase 3 ODYSSEY COMBO II study comparing alirocumab vs ezetimibe on top of statin in high cardiovascular risk patients with hypercholesterol…
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CLINICAL_TRIALS trial_result · 2015-11-06Clinical Trial Update: Efficacy and Safety of Alirocumab (SAR236553/REGN727) Versus Ezetimibe in Patients With Hypercholesterolemia [Phase 3]
Phase 3 trial comparing alirocumab (Praluent) to ezetimibe in patients with hypercholesterolemia assessed efficacy and safety. The study res…
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CLINICAL_TRIALS trial_result · 2015-11-06Clinical Trial Update: Efficacy and Safety of Alirocumab (SAR236553/REGN727) Versus Placebo on Top of Lipid-Modifying Therapy in Patients With High Cardiovascular Risk and Hypercholesterolemia (ODYSSEY COMBO I) [Phase 3]
Phase 3 ODYSSEY COMBO I evaluated alirocumab on top of lipid-modifying therapy in high-risk hypercholesterolemia; efficacy and safety result…
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CLINICAL_TRIALS trial_result · 2015-11-04Clinical Trial Update: Efficacy and Safety of Alirocumab (SAR236553/REGN727) Versus Placebo on Top of Lipid-Modifying Therapy in Patients With Heterozygous Familial Hypercholesterolemia Not Adequately Controlled With Their Lipid-Modifying Therapy [Phase 3]
Phase 3 trial evaluating the efficacy and safety of Alirocumab added to lipid-modifying therapy in patients with heterozygous familial hyper…
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CLINICAL_TRIALS trial_result · 2015-10-29Clinical Trial Update: Lipid-lowering Effect of a Plant Stanol Ester Supplement Product [NA]
A completed clinical trial from Raisio Group assessing the lipid-lowering effect of a plant stanol ester supplement (Benecol).
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CLINICAL_TRIALS trial_result · 2015-10-28Clinical Trial Update: Study of Alirocumab (REGN727/SAR236553) added-on to Rosuvastatin Versus Other Lipid Modifying Treatments (LMT) (ODYSSEY OPTIONS II) [Phase 3]
Phase 3 study evaluating alirocumab added to rosuvastatin versus other lipid-modifying treatments in hypercholesterolemia has completed with…
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CLINICAL_TRIALS trial_result · 2015-10-12Clinical Trial Update: Safety Study of BMS-823778 in Subjects With Hypercholesterolemia [Phase 2]
This clinical trial update reports the completion of a Phase 2 safety study of BMS-823778 in adults with hypercholesterolemia (dyslipidemia)…
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CLINICAL_TRIALS trial_result · 2015-10-09Clinical Trial Update: Study to Assess In-home Use of Evolocumab (AMG 145) Using a Prefilled Syringe or a Prefilled Autoinjector/Pen [Phase 3]
Phase 3 trial assessing in-home use of evolocumab via prefilled syringe or autoinjector; completed with posted results.
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CLINICAL_TRIALS trial_result · 2015-10-05Clinical Trial Update: A Study to Evaluate Tolerability and Efficacy of Evolocumab (AMG 145) in Japanese Subjects [Phase 2]
Phase 2 trial update evaluating tolerability and efficacy of evolocumab (AMG 145) in Japanese subjects with hypercholesterolemia and high ri…
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CLINICAL_TRIALS trial_result · 2015-10-05Clinical Trial Update: Monoclonal Antibody Against PCSK9 to Reduce Elevated Low-density Lipoprotein Cholesterol (LDL-C) in Adults Currently Not Receiving Drug Therapy for Easing Lipid Levels [Phase 2]
Phase 2 trial update on a monoclonal antibody targeting PCSK9 to lower LDL-C in adults not on lipid therapy; study completed with results po…
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CLINICAL_TRIALS trial_result · 2015-09-30Clinical Trial Update: IMPROVE-IT: Examining Outcomes in Subjects With Acute Coronary Syndrome: Vytorin (Ezetimibe/Simvastatin) vs Simvastatin (P04103) [Phase 3]
This document reports the completion and results posting of the IMPROVE-IT Phase 3 trial comparing Vytorin (ezetimibe/simvastatin) to simvas…
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CLINICAL_TRIALS trial_result · 2015-09-29Clinical Trial Update: Durable Effect of PCSK9 Antibody CompARed wiTh placEbo Study [Phase 3]
Phase 3 trial update comparing a PCSK9 antibody with placebo in hypercholesterolemia completed with results posted in 2015.
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CLINICAL_TRIALS trial_result · 2015-09-24Clinical Trial Update: Efficacy and Safety Evaluation of Alirocumab (SAR236553/REGN727) When Co-administered With High Dose of Atorvastatin in Patients With Primary Hypercholesterolemia [Phase 2]
Phase 2 study evaluating the efficacy and safety of alirocumab co-administered with high-dose atorvastatin in patients with hypercholesterol…
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CLINICAL_TRIALS trial_result · 2015-09-24Clinical Trial Update: Efficacy and Safety Evaluation of Alirocumab (SAR236553/REGN727) in Patients With Primary Hypercholesterolemia on Stable Atorvastatin Therapy in Japan [Phase 2]
This Phase 2 study evaluated the efficacy and safety of alirocumab (SAR236553/REGN727) in Japanese patients with primary hypercholesterolemi…
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CLINICAL_TRIALS trial_result · 2015-09-24Clinical Trial Update: Efficacy and Safety Evaluation of Alirocumab (SAR236553/REGN727) in Patients With Primary Hypercholesterolemia on Stable Atorvastatin Therapy [Phase 2]
Phase 2 trial evaluating the efficacy and safety of alirocumab in patients with primary hypercholesterolemia on stable atorvastatin therapy;…
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CLINICAL_TRIALS trial_result · 2015-09-22Clinical Trial Update: Study of the Safety and Efficacy of REGN727/SAR236553 in Patients With HeFH Hypercholesterolemia [Phase 2]
Phase 2 study evaluating the safety and efficacy of evolocumab (REGN727/SAR236553) in heterozygous familial hypercholesterolemia; the trial …
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CLINICAL_TRIALS trial_result · 2015-09-22Clinical Trial Update: Efficacy/Safety of HCP1306 Tablet Versus HGP0816 Tablet in Patients With Primary Hypercholesterolemia [Phase 3]
Phase 3 trial comparing HCP1306 versus HGP0816 tablets in patients with primary hypercholesterolemia has completed. The update provides info…