Hypercholesterolemia
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CLINICAL_TRIALS trial_result · 2016-09-28Clinical Trial Update: A Study to Evaluate the Effects of Dietary Fiber on Blood Lipids in Men and Women [NA]
A completed clinical trial evaluating the effects of dietary fiber on blood lipid levels in men and women with hypercholesterolemia.
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CLINICAL_TRIALS trial_result · 2016-09-28Clinical Trial Update: Effect of Alirocumab (SAR236553/REGN727) Administered on Top of Ezetimibe or Fenofibrate on Lipid Profiles in Healthy Subjects [Phase 1]
Phase 1 study evaluating the lipid-lowering effects of Alirocumab when added to ezetimibe or fenofibrate in healthy subjects; study complete…
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CLINICAL_TRIALS trial_result · 2016-09-23Clinical Trial Update: Nattokinase Supplementation and Hemostatic Factors [Phase 4]
Phase 4 trial update on nattokinase supplementation evaluating its impact on hemostatic factors in individuals with hypercholesterolemia; th…
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CLINICAL_TRIALS trial_result · 2016-08-03Clinical Trial Update: Dose-escalating Safety Study in Subjects on Stable Statin Therapy [Phase 2]
Phase 2 dose-escalation safety study in subjects on stable statin therapy for hypercholesterolemia has completed. The update reports safety …
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CLINICAL_TRIALS trial_result · 2016-08-03Clinical Trial Update: Safety and Tolerability of Varying Load and Dose of ISIS 301012 in People With Elevated LDL-cholesterol Levels [Phase 2]
This Phase 2 trial update reports safety and tolerability findings for varying doses of ISIS 301012 in adults with elevated LDL-cholesterol.…
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CLINICAL_TRIALS trial_result · 2016-08-03Clinical Trial Update: Study of ISIS 301012 (Mipomersen) in Heterozygous Familial Hypercholesterolemia Subjects on Lipid Lowering Therapy [Phase 2]
A phase 2 trial of mipomersen in patients with familial hypercholesterolemia on lipid-lowering therapy has completed.
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CLINICAL_TRIALS trial_result · 2016-08-02Clinical Trial Update: Effect On Serum Cholesterol Of Dairy Products With Addition Of Esterified Phytosterols [Phase 4]
This Phase 4 trial evaluates the effect of dairy products fortified with esterified phytosterols on serum cholesterol in people with dyslipi…
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CLINICAL_TRIALS trial_result · 2016-07-29Clinical Trial Update: Strong Heart Study
The Strong Heart Study, sponsored by the National Heart, Lung, and Blood Institute, has completed. The provided snippet does not include spe…
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CLINICAL_TRIALS trial_result · 2016-07-28Clinical Trial Update: Pilot Study To Assess CAT-2003 in Patients With Hyperlipidemia [Phase 2]
Phase 2 pilot study evaluating CAT-2003 in patients with dyslipidemia was completed.
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CLINICAL_TRIALS trial_result · 2016-07-11Clinical Trial Update: Proteus Discover in Subjects With Uncontrolled Hypertension and Type 2 Diabetes [NA]
This update notes the completed status of a clinical trial evaluating Proteus Discover in subjects with uncontrolled hypertension and type 2…
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CLINICAL_TRIALS trial_result · 2016-06-22Clinical Trial Update: Efficacy of Lapaquistat Acetate Co-Administered With Statins in Subjects With Hypercholesterolemia [Phase 3]
Phase 3 trial evaluating lapaquistat acetate co-administered with statins in hypercholesterolemia was terminated.
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CLINICAL_TRIALS trial_result · 2016-06-21Clinical Trial Update: Efficacy and Safety of Extended-Release Niacin/ Laropiprant/Simvastatin Tablets in Participants With Hypercholesterolemia or Mixed Dyslipidemia (MK-0524B-143) [Phase 3]
A Phase 3 trial evaluating an extended-release combination tablet of niacin, laropiprant, and simvastatin in individuals with primary hyperc…
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CLINICAL_TRIALS trial_result · 2016-06-10Clinical Trial Update: A Study to Evaluate the Effects of Ezetimibe (MK-0653) on the Postprandial (Following a Meal) Lipoprotein Response in Participants With Primary Hypercholesterolemia (High Cholesterol) (MK-0653-072)(COMPLETED) [Phase 3]
A Phase 3 study assessing ezetimibe (MK-0653) effects on postprandial lipoprotein response in adults with primary hypercholesterolemia; the …
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CLINICAL_TRIALS trial_result · 2016-05-23Clinical Trial Update: The Effectiveness of Plant Stanols as Ester on Change in Blood Cholesterol Level [NA]
A completed clinical trial from Yonsei University evaluated the effect of plant stanol esters on changes in LDL-cholesterol levels.
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CLINICAL_TRIALS trial_result · 2016-05-18Clinical Trial Update: Atorvastatin Study in Cardiovascular Disease Risk
A completed clinical trial evaluating atorvastatin for cardiovascular disease risk in patients with hypercholesterolemia or dyslipidemia.
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CLINICAL_TRIALS trial_result · 2016-05-18Clinical Trial Update: Cholesterol Medication Packaging Study [NA]
Completed clinical trial focusing on packaging for a cholesterol-lowering medication; results have been posted.
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CLINICAL_TRIALS trial_result · 2016-05-16Clinical Trial Update: Evaluation of Efficacy and Safety of AVE5530 Co-administered With Atorvastatin in Primary Hypercholesterolemia [Phase 3]
A Phase 3 trial evaluating AVE5530 co-administered with atorvastatin for primary hypercholesterolemia was terminated; the update discusses e…
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CLINICAL_TRIALS trial_result · 2016-05-16Clinical Trial Update: Evaluation of Safety and Efficacy of AVE5530 as add-on to Ongoing Statins in Patients With Primary Hypercholesterolemia [Phase 3]
Phase 3 trial evaluating AVE5530 as add-on to ongoing statin therapy in primary hypercholesterolemia has been terminated.
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CLINICAL_TRIALS trial_result · 2016-05-16Clinical Trial Update: Evaluation of Efficacy and Safety of AVE5530 in Patients With Primary Hypercholesterolemia [Phase 3]
Phase 3 clinical trial evaluating AVE5530 for primary hypercholesterolemia has been terminated. The update notes the assessment of its effic…
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CLINICAL_TRIALS trial_result · 2016-05-16Clinical Trial Update: Evaluation of Safety and Efficacy of AVE5530 as add-on to Ongoing High Doses of Statins in Patients With Primary Severe Hypercholesterolemia [Phase 3]
A Phase 3 trial evaluating AVE5530 as add-on to ongoing high-dose statins in primary severe hypercholesterolemia was terminated.
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CLINICAL_TRIALS trial_result · 2016-05-13Clinical Trial Update: Postmenopausal Estrogen/Progestin Interventions (PEPI) [Phase 3]
Phase 3 PEPI trial completed. The study evaluated postmenopausal estrogen/progestin interventions for effects on bone health and cardiovascu…
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CLINICAL_TRIALS trial_result · 2016-05-13Clinical Trial Update: Diet and Plasma Cholesterol - Secular Trend Analysis
This completed clinical trial update reports on secular trend analysis of diet and plasma cholesterol from an NHLBI study. It relates to car…
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CLINICAL_TRIALS trial_result · 2016-05-13Clinical Trial Update: Primary Prevention of CHD Risk Factors Occurring in US
ClinicalTrials.gov update from NHLBI describes a completed US study focused on primary prevention of coronary heart disease risk factors. Th…
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CLINICAL_TRIALS trial_result · 2016-05-13Clinical Trial Update: Women's Healthy Lifestyle Project: Cardiovascular Risk Factors and Menopause [Phase 3]
Phase 3 Women's Healthy Lifestyle Project update evaluating cardiovascular risk factors in relation to menopause; the trial is reported as c…
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CLINICAL_TRIALS trial_result · 2016-05-13Clinical Trial Update: Lipid Variability--Influence of Stress
The NHLBI-sponsored clinical trial investigating how stress affects lipid variability has completed.