Hypercholesterolemia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2017-07-24Clinical Trial Update: Replacement of Saturated Fat in Dairy on Total Cholesterol [NA]
A completed clinical trial evaluated whether replacing saturated fat in dairy products with unsaturated fats affects total cholesterol in in…
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CLINICAL_TRIALS trial_result · 2017-06-26Clinical Trial Update: Evaluation of Alirocumab in Addition to Lipid-Modifying Therapy in Patients With High Cardiovascular Risk and Hypercholesterolemia in South Korea and Taiwan [Phase 3]
This is a Phase 3 trial evaluating alirocumab added to lipid-modifying therapy in high cardiovascular risk patients with hypercholesterolemi…
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CLINICAL_TRIALS trial_result · 2017-06-23Clinical Trial Update: Genetically Guided Statin Therapy [NA]
This clinical trial update describes the completion and posted results of a Duke-led study evaluating genetically guided statin therapy for …
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CLINICAL_TRIALS trial_result · 2017-06-21Clinical Trial Update: A Clinical Trial to Assess the Efficacy and Safety of MK-0653C in Japanese Participants With Hypercholesterolemia (MK-0653C-383) [Phase 3]
Phase 3 clinical trial evaluating MK-0653C in Japanese participants with hypercholesterolemia has completed and results have been posted.
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CLINICAL_TRIALS trial_result · 2017-06-21Clinical Trial Update: A Study of LY3015014 in Participants With High Cholesterol [Phase 2]
Phase 2 trial update for LY3015014 in participants with high cholesterol (hypercholesterolemia) has completed with results posted in 2017.
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CLINICAL_TRIALS trial_result · 2017-06-20Clinical Trial Update: Acotral® Versus Zetia® Ezetimibe Bioequivalance Study. [Phase 1]
A Phase 1 bioequivalence study comparing Acotral with Zetia (ezetimibe) in hypercholesterolemia, with the trial status reported as completed…
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CLINICAL_TRIALS trial_result · 2017-06-20Clinical Trial Update: Rosuvastatin Calcium Bioequivalence Study - Fast [Phase 1]
Phase 1 bioequivalence study of rosuvastatin calcium completed for hypercholesterolemia.
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CLINICAL_TRIALS trial_result · 2017-06-20Clinical Trial Update: A Study to Assess the Safety and Efficacy of CAT-2054 in Combination With Atorvastatin in Patients With Hypercholesterolemia [Phase 2]
This entry reports on a Phase 2 clinical trial evaluating the safety and efficacy of CAT-2054 in combination with atorvastatin for hyperchol…
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CLINICAL_TRIALS trial_result · 2017-06-20Clinical Trial Update: Effect of Crestor on Lipoprotein Metabolism in Humans [Phase 4]
The document reports the completion of a Phase 4 trial evaluating the effects of rosuvastatin (Crestor) on lipoprotein metabolism in humans …
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CLINICAL_TRIALS trial_result · 2017-06-01Clinical Trial Update: A Defined, Plant-based, 4-week Dietary Intervention Reduces Lp(a) and Other Atherogenic Particles [NA]
A defined, plant-based, four-week dietary intervention reduced Lp(a) and other atherogenic particles in adults with hypercholesterolemia, ac…
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CLINICAL_TRIALS trial_result · 2017-05-23Clinical Trial Update: Effects of a 4-week Raw, Plant-based Diet on Anthropometric and Cardiovascular Risk Factors [NA]
A completed study evaluated the impact of a 4-week raw, plant-based diet on anthropometric measures and cardiovascular risk factors.
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CLINICAL_TRIALS trial_result · 2017-05-02Clinical Trial Update: Effect of Alirocumab on Lipid Metabolism in Adults With Elevated LDL-Cholesterol [Phase 1]
Phase 1 trial evaluating the effect of Alirocumab on lipid metabolism in adults with elevated LDL-cholesterol has completed. The study asses…
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CLINICAL_TRIALS trial_result · 2017-05-02Clinical Trial Update: Fabulous Fibre Study - Effect of Wheat Bran Extract on Gut and General Health in Healthy Aging Subjects (FFS) [NA]
The record notes the completed trial of wheat bran extract on gut and general health in healthy aging adults. The snippet does not include r…
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CLINICAL_TRIALS trial_result · 2017-04-17Clinical Trial Update: A Study of the Safety and Efficacy of Anacetrapib (MK-0859) When Added to Ongoing Statin Therapy (MK-0859-021) [Phase 3]
A Phase 3 trial evaluating the safety and efficacy of adding Anacetrapib to ongoing statin therapy in hypercholesterolemia has completed.
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CLINICAL_TRIALS trial_result · 2017-04-17Clinical Trial Update: Evaluation of Ubiquinol on Mitochondrial Oxidative Capacity in Statin Patients Using 31PMRS [NA]
A completed clinical trial evaluated the effect of ubiquinol on mitochondrial oxidative capacity in statin users and posted results.
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CLINICAL_TRIALS trial_result · 2017-04-07Clinical Trial Update: MK0524A Clinical Efficacy Study (0524A-026)(COMPLETED) [Phase 2]
This update summarizes the completed Phase 2 efficacy study (0524A-026) of MK0524A for hypercholesterolemia.
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CLINICAL_TRIALS trial_result · 2017-04-07Clinical Trial Update: Lipid Efficacy Study (0524B-022)(COMPLETED) [Phase 3]
A Phase 3 lipid efficacy trial sponsored by Merck Sharp & Dohme LLC has completed (Study 0524B-022) for primary hypercholesterolemia and mix…
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CLINICAL_TRIALS trial_result · 2017-03-21Clinical Trial Update: Study to Evaluate the Efficacy and Safety of an Every Four Weeks Treatment Regimen of Alirocumab (REGN727/ SAR236553) in Patients With Primary Hypercholesterolemia (ODYSSEY CHOICE 1) [Phase 3]
Phase 3 study ODYSSEY CHOICE 1 evaluated the efficacy and safety of an every-four-weeks dosing regimen of alirocumab (Praluent) in patients …
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CLINICAL_TRIALS trial_result · 2017-03-17Clinical Trial Update: The Effects of Lowering Low-density Lipoprotein Cholesterol Levels to New Targets on Cardiovascular Complications in Peritoneal Dialysis Patients [NA]
Clinical trial evaluating whether lowering LDL cholesterol to new targets reduces cardiovascular complications in peritoneal dialysis patien…
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CLINICAL_TRIALS trial_result · 2017-03-15Clinical Trial Update: Phase III Study To Evaluate Alirocumab in Patients With Hypercholesterolemia Not Treated With a Statin (ODYSSEY CHOICE II) [Phase 3]
Phase III ODYSSEY CHOICE II evaluated alirocumab in patients with hypercholesterolemia not treated with a statin; results were posted in Mar…
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CLINICAL_TRIALS trial_result · 2017-02-28Clinical Trial Update: Effect of Red Yeast Rice, Phytosterols and L-tyrosol on Lipid Profile and Endothelial Function [NA]
A completed clinical trial evaluated the effects of red yeast rice, phytosterols, and L-tyrosol on lipid profile and endothelial function in…
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CLINICAL_TRIALS trial_result · 2017-02-23Clinical Trial Update: A 10-12 Week Study to Evaluate the Safety and Efficacy of 320 mg Valsartan and 80 mg Simvastatin in Combination and as Monotherapies in Treating Hypertension and Hypercholesterolemia [Phase 3]
A completed Phase 3 trial evaluating a fixed combination of valsartan 320 mg and simvastatin 80 mg versus monotherapies for hypertension and…
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CLINICAL_TRIALS trial_result · 2017-02-23Clinical Trial Update: Efficacy and Safety of Fluvastatin in Different Doses in Adults With Mixed Dyslipidemia or Primary Hypercholesterolemia [Phase 3]
This entry notes the completion of a Phase 3 trial evaluating different doses of fluvastatin for efficacy and safety in adults with mixed dy…
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CLINICAL_TRIALS trial_result · 2017-02-16Clinical Trial Update: Effect of an Investigational Compound on Tolerability of Extended Release Niacin (0524A-023)(COMPLETED) [Phase 3]
Phase 3 trial update showing completion of a study evaluating an investigational compound's effect on the tolerability of extended-release n…
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CLINICAL_TRIALS trial_result · 2017-02-16Clinical Trial Update: Tolerability of MK0524A Versus Niacin Extended-Release (0524A-054) [Phase 3]
Phase 3 trial comparing tolerability of MK0524A to niacin extended-release in patients with high cholesterol has completed.