Hypercholesterolemia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2019-03-14Clinical Trial Update: A Study of the Safety and Efficacy of Two Different Regimens of Mipomersen in Patients With Familial Hypercholesterolemia and Inadequately Controlled Low-Density Lipoprotein Cholesterol [Phase 3]
Phase 3 trial evaluating two regimens of mipomersen in patients with familial hypercholesterolemia and inadequately controlled LDL cholester…
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CLINICAL_TRIALS trial_result · 2019-02-25Clinical Trial Update: A Study of LY3015014 in Healthy Participants With High Cholesterol [Phase 1]
Phase 1 trial update for LY3015014 in healthy participants with high cholesterol has completed with results posted.
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CLINICAL_TRIALS trial_result · 2019-02-18Clinical Trial Update: Study to Evaluate Efficacy and Safety of LIB003 in Patients on Lipid-Lowering Therapy Needing Additional LDL-C Reduction [Phase 2]
Phase 2 study evaluating LIB003 for additional LDL-C reduction in patients on lipid-lowering therapy has completed. The trial assessed effic…
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CLINICAL_TRIALS trial_result · 2019-02-15Clinical Trial Update: Effects of Nutraceutical Therapies on Endothelial Function, Platelet Aggregation, and Coronary Flow Reserve [NA]
This clinical trial update reports on a completed study evaluating nutraceutical therapies for endothelial function, platelet aggregation, a…
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CLINICAL_TRIALS trial_result · 2019-02-12Clinical Trial Update: Effects of a Supplement Derived From Palm Oil on Cholesterol Levels in the Blood [Phase 3]
Phase 3 trial evaluating a palm oil-derived supplement for lowering blood cholesterol in hypercholesterolemia was terminated, with results p…
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CLINICAL_TRIALS trial_result · 2019-02-08Clinical Trial Update: Dose Ranging Study Of Bococizumab (PF-04950615; RN316) In Hypercholesterolemic Japanese Subjects [Phase 2]
Pfizer conducted a Phase 2 dose-ranging study of bococizumab in Japanese patients with hypercholesterolemia; the trial has completed and res…
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CLINICAL_TRIALS trial_result · 2019-01-22Clinical Trial Update: Safety And Tolerability Of Multiple Doses Of PF-04950615 (RN316) In Subjects With Hypercholesterolemia [Phase 1]
A Phase 1 study evaluated the safety and tolerability of multiple doses of PF-04950615 (RN316) in adults with hypercholesterolemia. The stud…
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CLINICAL_TRIALS trial_result · 2018-12-04Clinical Trial Update: A Clinical Trial to Assess the Long Term Safety and Tolerability of MK-0653H in Japanese Participants With Hypercholesterolemia (MK-0653H-833) [Phase 3]
A completed Phase 3 trial assessing the long-term safety and tolerability of MK-0653H in Japanese participants with hypercholesterolemia; re…
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CLINICAL_TRIALS trial_result · 2018-11-01Clinical Trial Update: A Study of MK-6213 Co-Administered With Atorvastatin in Participants With Hypercholesterolemia (MK-6213-006) [Phase 2]
Phase 2 trial evaluating MK-6213 with statin atorvastatin in hypercholesterolemia completed; results posted in 2018.
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CLINICAL_TRIALS trial_result · 2018-10-31Clinical Trial Update: Randomized Trial of Imaging Versus Risk Factor-Based Therapy for Plaque Regression [Phase 4]
A Phase 4 randomized trial compared imaging-based therapy to risk-factor-based therapy for plaque regression in atherosclerosis and hypercho…
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CLINICAL_TRIALS trial_result · 2018-10-18Clinical Trial Update: Efficacy and Safety Study of HS-25 in Chinese Adults With Primary Hypercholesterolemia [Phase 3]
Phase 3 trial evaluating efficacy and safety of HS-25 in Chinese adults with primary hypercholesterolemia has completed.
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CLINICAL_TRIALS trial_result · 2018-10-18Clinical Trial Update: Efficacy and Safety of HS-25 or in Combination With Atorvastatin in Chinese Adults With Primary Hypercholesterolemia [Phase 3]
Phase 3 trial update evaluating HS-25 alone or in combination with atorvastatin in Chinese adults with primary hypercholesterolemia.
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CLINICAL_TRIALS trial_result · 2018-10-15Clinical Trial Update: Study Evaluating Novel Biomarkers of AKI (Acute Kidney Injury) in Post-operative Patients [Phase 4]
Phase 4 clinical trial evaluating novel biomarkers of acute kidney injury in post-operative patients was terminated.
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CLINICAL_TRIALS trial_result · 2018-10-09Clinical Trial Update: A Study of Evacetrapib (LY2484595) in Combination With Atorvastatin in Japanese Participants With Primary Hypercholesterolemia [Phase 3]
Phase 3 trial of Evacetrapib (LY2484595) with atorvastatin in Japanese participants with primary hypercholesterolemia was terminated; result…
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CLINICAL_TRIALS trial_result · 2018-10-09Clinical Trial Update: A Study of Evacetrapib (LY2484595) in Japanese Participants With Primary Hypercholesterolemia [Phase 3]
Phase 3 trial of evacetrapib in Japanese participants with primary hypercholesterolemia was terminated; results posted in 2018.
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CLINICAL_TRIALS trial_result · 2018-08-31Clinical Trial Update: Evaluation of Evolocumab (AMG 145) Efficacy in Diabetic Adults With Hypercholesterolemia/Mixed Dyslipidemia [Phase 3]
Phase 3 trial evaluating evolocumab in diabetic adults with hypercholesterolemia or mixed dyslipidemia has completed with results posted.
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CLINICAL_TRIALS trial_result · 2018-08-31Clinical Trial Update: Goal Achievement After Utilizing an Anti-PCSK9 Antibody in Statin Intolerant Subjects-4 [Phase 3]
Phase 3 trial update assessing goal achievement with an anti-PCSK9 antibody in statin-intolerant subjects for hypercholesterolemia.
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CLINICAL_TRIALS trial_result · 2018-08-14Clinical Trial Update: Efficacy and Safety of Combination of Rosuvastatin and Ezetimibe in Patients With Primary Hypercholesterolemia [Phase 3]
Phase 3 trial assessing the efficacy and safety of rosuvastatin in combination with ezetimibe for primary hypercholesterolemia has completed…
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CLINICAL_TRIALS trial_result · 2018-07-27Clinical Trial Update: Study to Evaluate the Safety, PK, and Pharmacodynamics of LIB003 [Phase 1]
A Phase 1 study evaluating the safety, pharmacokinetics, and pharmacodynamics of LIB003 in Hypercholesterolemia has completed. The trial was…
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CLINICAL_TRIALS trial_result · 2018-07-24Clinical Trial Update: Open Label Study of Long Term Safety Evaluation of Alirocumab [Phase 3]
Open-label, long-term safety study of Alirocumab (Praluent) in adults with hypercholesterolemia. Phase 3 trial results were posted in 2018.
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CLINICAL_TRIALS trial_result · 2018-07-23Clinical Trial Update: A Pharmacokinetic and Pharmacodynamic Study of PF-04950615 (RN316) in Subjects With Hypercholesterolemia [Phase 1]
Phase 1 pharmacokinetic and pharmacodynamic study of PF-04950615 (RN316) in subjects with hypercholesterolemia, with results posted.
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CLINICAL_TRIALS trial_result · 2018-07-05Clinical Trial Update: Effects of Two Herbal Dietary Supplements on Lipid Metabolism in Moderate Hypercholesterolemia and Hypertriglyceridemia [Phase 1, Phase 2]
Clinical trial update on two herbal dietary supplements evaluating lipid metabolism in moderate hypercholesterolemia and hypertriglyceridemi…
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CLINICAL_TRIALS trial_result · 2018-07-05Clinical Trial Update: Clinical Trial of Protein and Blood Pressure [NA]
A completed clinical trial update for a study investigating protein and blood pressure in hypertension and hypercholesterolemia; results pos…
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CLINICAL_TRIALS trial_result · 2018-06-13Clinical Trial Update: A Clinical Trial to Compare the Efficacy and Safety of a Combination Therapy of Ezetimibe and Rosuvastatin Versus Monotherapy of Rosuvastatin in Hypercholesterolemia Patients (I-ROSETTE Study) [Phase 3]
A Phase 3 trial comparing the combination of ezetimibe and rosuvastatin versus rosuvastatin alone in hypercholesterolemia has completed.
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CLINICAL_TRIALS trial_result · 2018-06-08Clinical Trial Update: Low Fat Vegan or American Heart Association Diets & Cardiovascular Risk in Obese 9-18 y.o. With Elevated Cholesterol [NA]
Clinical trial comparing low-fat vegan vs American Heart Association diets in obese children with elevated cholesterol; study completed with…