Hypercholesterolemia
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CLINICAL_TRIALS research · 2025-03-25Clinical Trial Update: Effect of LIMICOL®-NG on Plasma LDL-cholesterol Concentration in Subjects with Moderate Hypercholesterolemia [NA]
A clinical trial is evaluating the effect of LIMICOL®-NG on plasma LDL-cholesterol in adults with moderate hypercholesterolemia; the study i…
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CLINICAL_TRIALS research · 2025-03-20Clinical Trial Update: A Study to Compare PK Characteristics and Safety Profiles Between AD-228B and AD-2284 [Phase 1]
Phase 1 trial comparing pharmacokinetics and safety profiles of two investigational agents, AD-228B and AD-2284. The study is currently recr…
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CLINICAL_TRIALS research · 2025-03-14Clinical Trial Update: A Study on Evaluating the Safety of HST101 in Healthy Chinese Participants [Phase 1]
Phase 1 safety study of HST101 in healthy Chinese participants, currently enrolling by invitation to assess safety in individuals with hyper…
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CLINICAL_TRIALS research · 2025-03-05Clinical Trial Update: PMMHRI-Pitavastatin Registry
Clinical trial registry update for the PMMHRI-Pitavastatin Registry, targeting hypercholesterolemia with recruitment ongoing.
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CLINICAL_TRIALS research · 2025-02-12Clinical Trial Update: Functional Cereal Products and Contribution to the Regulation of Metabolism and Obesity-induced Chronic Low-grade Inflammation. [NA]
A clinical trial update indicating Harokopio University is enrolling participants in a study of functional cereal products to regulate metab…
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CLINICAL_TRIALS research · 2025-02-05Clinical Trial Update: Evaluation of the Effects of Two Dietary Supplement Formulations on the Lipid Profile in Mild Hypercholesterolemia [NA]
A clinical trial is evaluating two dietary supplement formulations for their effect on lipid profiles in adults with mild hypercholesterolem…
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CLINICAL_TRIALS research · 2025-02-04Clinical Trial Update: A Study to Evaluate the Efficacy and Safety of Co-administration of AD-2281 and AD-2282 [Phase 3]
This document reports a Phase 3 clinical trial to evaluate the efficacy and safety of co-administration of AD-2281 and AD-2282 for Primary H…
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CLINICAL_TRIALS research · 2024-12-27Clinical Trial Update: Study of QLC7401 in the Treatment of Primary Hypercholesterolemia or Mixed Hyperlipidemia With Elevated LDL Cholesterol [Phase 2]
This entry covers a Phase 2 clinical trial of QLC7401 for primary hypercholesterolemia or mixed hyperlipidemia with elevated LDL, which is n…
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CLINICAL_TRIALS research · 2024-12-17Clinical Trial Update: Genetic Testing and Motivational Counseling for FH [NA]
This clinical trial update describes an ongoing study evaluating genetic testing and motivational counseling to support adherence in people …
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CLINICAL_TRIALS research · 2024-12-05Clinical Trial Update: A Phase 3 Clinical Trial to Evaluate the Efficacy and Safety of AG2304T and AG2304R [Phase 3]
A Phase 3 clinical trial is planned to evaluate the efficacy and safety of AG2304T and AG2304R for hypercholesterolemia; the study is not ye…
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CLINICAL_TRIALS research · 2024-11-22Clinical Trial Update: RCT for the Chinese Medicine in Treating Hypercholesterolemia [Phase 2]
A Phase 2 randomized trial evaluating a Chinese medicine formulation for hypercholesterolemia; the study is currently not yet recruiting.
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CLINICAL_TRIALS research · 2024-11-06Clinical Trial Update: In Vitro Demonstration of Direct Platelet-Related Effects of PCSK9 Enzyme
An in vitro study demonstrates direct platelet-related effects of the PCSK9 enzyme; the trial is not yet recruiting.
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CLINICAL_TRIALS research · 2024-11-04Clinical Trial Update: Natural Heart Health Supplement Trial [Phase 1]
Phase 1 clinical trial update for a natural heart health supplement from Efforia, Inc, evaluating effects on cholesterol (total and HDL); th…
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CLINICAL_TRIALS research · 2024-10-22Clinical Trial Update: Long-term Efficacy and Safety of OLE LIB003 in HoFH, HeFH, and High-risk CVD Patients Requiring Further LDL-C Reduction [Phase 3]
Phase 3 open-label extension evaluating long-term efficacy and safety of LIB003 in patients with homozygous and heterozygous familial hyperc…
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CLINICAL_TRIALS research · 2024-09-19Clinical Trial Update: A Real-world Study to Assess the Characteristics and Long-term Effectiveness of Inclisiran in Chinese Adult Patients
This completed real-world study evaluates the characteristics and long-term effectiveness of Inclisiran in Chinese adults with hypercholeste…
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CLINICAL_TRIALS research · 2024-09-19Clinical Trial Update: Efficacy and Safety of JS002 as Monotherapy in Patients With Primary Hypercholesterolaemia and Mixed Dyslipidemia [Phase 3]
A Phase 3 clinical trial is evaluating JS002 as monotherapy for primary hypercholesterolemia and mixed dyslipidemia. The study is currently …
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CLINICAL_TRIALS research · 2024-08-23Clinical Trial Update: Extra Virgin Olive Oil Supplementation in Pregnancies With Increased Cholesterol Levels [NA]
Clinical trial update on extra virgin olive oil supplementation in pregnancies with high cholesterol; the study is not yet recruiting.
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CLINICAL_TRIALS research · 2024-07-19Clinical Trial Update: PET Imaging of Inflammation and Lipid Lowering Study [NA]
This is a clinical trial update indicating that a PET imaging study of inflammation and lipid lowering (NCT04073797) sponsored by the Univer…
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CLINICAL_TRIALS research · 2024-07-01Clinical Trial Update: Plant Sterols on Cardiovascular Markers, Microbiota and Sterol Metabolism (Cardiofoodsterol) [NA]
Clinical trial update indicating recruitment is ongoing for Cardiofoodsterol, a study evaluating the effects of plant sterols on cardiovascu…
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CLINICAL_TRIALS research · 2024-07-01Clinical Trial Update: Effect of the Food Supplement TOTUM-070 on Lipid Metabolism [NA]
Clinical trial update on TOTUM-070 evaluating its effects on lipid metabolism in adults with hypercholesterolemia. The trial is currently ac…
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CLINICAL_TRIALS research · 2024-06-06Clinical Trial Update: Chart Review of Repatha® in Subjects With Hyperlipidaemia
This is a completed chart-review study evaluating the use of Repatha (evolocumab) in subjects with hyperlipidemia and/or hypercholesterolemi…
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CLINICAL_TRIALS research · 2024-05-24Clinical Trial Update: Effects of Phytoestrogen From Pueraria Mirifica in Improvement of Serum Lipid Parameters in Postmenopausal Women [Phase 2, Phase 3]
A clinical trial is evaluating a phytoestrogen extract from Pueraria mirifica for improving serum lipid parameters in postmenopausal women, …
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CLINICAL_TRIALS research · 2024-05-20Clinical Trial Update: Effect of a Customised Lifestyle Medicine Strategy on Lowering Blood Lipid Levels in Indian Physicians [NA]
This clinical trial update reports on a study evaluating a customized lifestyle medicine approach to lower lipid levels in Indian physicians…
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CLINICAL_TRIALS research · 2024-05-08Clinical Trial Update: Effect of a Dietary Supplement on Lipid Pattern, Indexes of NAFLD and Systemic Inflammation in Healthy Subjects With Suboptimal LDL-C Levels [NA]
Clinical trial update from the University of Bologna evaluating the effects of a dietary supplement on lipid patterns, indices related to no…
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CLINICAL_TRIALS research · 2023-10-04Clinical Trial Update: Japan Assessment of Pitavastatin and Atorvastatin in Acute Coronary Syndrome (JAPAN-ACS) [Phase 4]
A Phase 4 trial update assessing pitavastatin and atorvastatin in patients with acute coronary syndrome in Japan.