Huntington Disease
📧 Sign up to get email alerts when something new happens for Huntington Disease.
Sign up freeTop drugs studied for this disease
-
CLINICAL_TRIALS research · 2025-05-01Clinical Trial Update: ExAblate Transcranial MRgFUS for the Management of Treatment-Refractory Movement Disorders [NA]
Clinical trial update on ExAblate Transcranial MRgFUS for treatment-refractory movement disorders; the study is currently active but not rec…
-
CLINICAL_TRIALS research · 2025-04-24Clinical Trial Update: Huntington's Disease Biobank: Advancing Remote Monitoring and Deep Phenotyping
Clinical trial update for a Huntington's disease biobank by Stanford University, focusing on remote monitoring and deep phenotyping; the stu…
-
CLINICAL_TRIALS trial_result · 2025-03-21Clinical Trial Update: Risperidone for the Treatment of Huntington's Disease Involuntary Movements [Phase 2]
Phase 2 trial evaluating risperidone for involuntary movements in Huntington's disease (chorea) has completed with results posted.
-
CLINICAL_TRIALS research · 2025-03-19Clinical Trial Update: The NAD-HD Study: A Study to Investigate Efficacy and Safety of Nicotinamide Riboside Compared With Placebo in Huntington's Disease [Phase 2]
A Phase 2 clinical trial evaluating nicotinamide riboside versus placebo for Huntington's disease is currently recruiting.
-
CLINICAL_TRIALS trial_result · 2025-03-18Clinical Trial Update: Preparing for Prevention of Huntington's Disease (PREVENT-HD)
The PREVENT-HD trial for Huntington's disease prevention, sponsored by the University of Wisconsin–Madison, has completed.
- Want full summaries, importance scores, and drug timelines? Upgrade to Plus or Pro.
-
CLINICAL_TRIALS trial_result · 2025-03-17Clinical Trial Update: Handgrip and Respiratory Dysfunction in HD Patients.
This clinical trial update indicates that the study evaluating handgrip strength and respiratory dysfunction in Huntington disease patients …
-
CLINICAL_TRIALS trial_result · 2025-03-12Clinical Trial Update: PRidopidine's Outcome On Function in Huntington Disease, PROOF- HD [Phase 3]
The PROOF-HD Phase 3 trial evaluating pridopidine's impact on function in Huntington disease has completed, and the results have been posted…
-
CLINICAL_TRIALS trial_result · 2025-03-10Clinical Trial Update: Safety and Efficacy of AMT-130 in European Adults With Early Manifest Huntington's Disease [Phase 1, Phase 2]
Clinical trial update describes the safety and efficacy evaluation of AMT-130 in European adults with early manifest Huntington disease acro…
-
CLINICAL_TRIALS research · 2025-03-05Clinical Trial Update: IMarkHD: in Vivo Longitudinal Imaging of HD Pathology
Clinical trial update on the IMarkHD study, which investigates in vivo longitudinal imaging of Huntington's disease pathology. Recruitment i…
-
CLINICAL_TRIALS trial_result · 2025-03-03Clinical Trial Update: Study to Assess the Safety, Pharmacokinetics, and Pharmacodynamics of MBF-015 in Huntington's Disease Patients [Phase 2]
A Phase 2 clinical trial evaluating MBF-015 for Huntington disease has completed, reporting on safety, pharmacokinetics, and pharmacodynamic…
-
CLINICAL_TRIALS research · 2025-03-03Clinical Trial Update: NYSCF Scientific Discovery Biobank
Clinical trial entry for the NYSCF Scientific Discovery Biobank (NCT06203106) shows recruiting status and lists indications including amyotr…
-
FDA approval · 2025-02-28FDA Approved: AUSTEDO XR — Supplemental Application (Teva Neuroscience, Inc.)
FDA approved a supplemental application for AUSTEDO XR (deutetrabenazine) from Teva Neuroscience, Inc. The action involves the extended-rele…
-
FDA approval · 2025-02-28FDA Approved: AUSTEDO — Supplemental Application (Teva Neuroscience, Inc.)
FDA approved a supplemental application for Austedo (deutetrabenazine) from Teva Neuroscience, Inc. The approval updates the labeling for th…
-
CLINICAL_TRIALS research · 2025-02-28Clinical Trial Update: A Randomised Controlled Trial, Of N-Acetyl Cysteine (NAC), for Premanifest Huntingtin Gene Expansion Carriers [Phase 2]
A Phase 2 randomized trial evaluating N-Acetyl Cysteine (NAC) in premanifest Huntington's disease gene expansion carriers; recruitment is on…
-
CLINICAL_TRIALS trial_result · 2025-02-27Clinical Trial Update: Efficacy of Deutetrabenazine to Control Symptoms of Dysphagia Associated with HD [Phase 1]
Phase 1 trial of deutetrabenazine for dysphagia in Huntington disease was terminated; no conclusive efficacy results are reported.
-
CLINICAL_TRIALS research · 2025-02-25Clinical Trial Update: Trial of the Combined Use of Thiamine and Biotin in Patients With Huntington's Disease [Phase 2]
A Phase 2 clinical trial is recruiting to evaluate the combined use of thiamine and biotin in Huntington's disease.
-
FDA approval · 2025-01-22FDA Approved: HALOPERIDOL — Supplemental Application (Fresenius Kabi USA, LLC)
FDA approved a supplemental application for Haloperidol lactate from Fresenius Kabi USA, LLC.
-
FDA approval · 2025-01-22FDA Approved: HALOPERIDOL — Supplemental Application (Lannett Company, Inc.)
The FDA approved a supplemental application for HALOPERIDOL submitted by Lannett Company, Inc., authorizing changes to the product's approva…
-
CLINICAL_TRIALS research · 2025-01-20Clinical Trial Update: Early Biomarkers in Premanifest Huntington's Disease Gene Carriers: a Pilot Study [NA]
Pilot clinical trial evaluating early biomarkers in premanifest Huntington disease gene carriers, currently recruiting at University Hospita…
-
CLINICAL_TRIALS research · 2025-01-14Clinical Trial Update: Neurobiological Predictors of Huntington's Disease (PREDICT-HD)
Clinical trial update on the PREDICT-HD study, which investigates neurobiological predictors of Huntington's disease; the study status is AC…
-
CLINICAL_TRIALS trial_result · 2025-01-03Clinical Trial Update: Study to Measure Cerebrospinal Fluid Mutant Huntingtin Protein in Participants With Early Manifest Stage I or Stage II Huntington's Disease [Phase 1]
Roche completed a Phase 1 biomarker study in early manifest Huntington's disease to measure cerebrospinal fluid mutant huntingtin protein; r…
-
CLINICAL_TRIALS research · 2024-12-24Clinical Trial Update: Open-Label Rollover Study for Continuing Valbenazine Administration for the Treatment of Chorea Associated With Huntington Disease [Phase 3]
Open-label rollover study continuing valbenazine for the treatment of chorea in Huntington disease (Phase 3); currently active but not recru…
-
CLINICAL_TRIALS trial_result · 2024-12-20Clinical Trial Update: Measurement and Modification of Threat Interpretation Bias in Neurodegenerative Movement Disorders (Aims 2 & 3) [NA]
Completed clinical trial evaluating measurement and modification of threat interpretation bias in Huntington's disease and Parkinson's disea…
-
CLINICAL_TRIALS research · 2024-12-13Clinical Trial Update: Longitudinal SV2A and MRI in Premanifest HD [NA]
Clinical trial update for Huntington disease evaluating SV2A and MRI in premanifest patients, currently recruiting.
-
CLINICAL_TRIALS research · 2024-12-13Clinical Trial Update: Gene Therapy Development and Validation for Huntington's Disease Fibro TG-HD [NA]
This trial update notes a Huntington's disease gene therapy (TG-HD) being developed at University Hospital Angers and currently recruiting.