High-grade Glioma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2024-04-02Clinical Trial Update: Efficacy of Nivolumab for Recurrent IDH Mutated High-Grade Gliomas [Phase 2]
Phase 2 clinical trial update evaluating nivolumab for recurrent IDH-mutated high-grade gliomas has completed.
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CLINICAL_TRIALS trial_result · 2024-03-26Clinical Trial Update: Effect of Electroacupuncture Combined With Paclitaxel Clinical Efficacy of Patients With Recurrence of High-grade Glioma [Phase 3]
A Phase 3 clinical trial evaluating electroacupuncture combined with paclitaxel for recurrent high-grade glioma is currently recruiting.
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CLINICAL_TRIALS trial_result · 2024-03-06Clinical Trial Update: Study of Binimetinib With Encorafenib in Adults With Recurrent BRAF V600-Mutated HGG [Phase 2]
A Phase 2 study of the MEK inhibitor binimetinib plus the BRAF inhibitor encorafenib in adults with recurrent BRAF V600-mutant high-grade gl…
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CLINICAL_TRIALS trial_result · 2023-07-03Clinical Trial Update: Low Dose Radiation Therapy for Glioblastoma Multiforme [Phase 2]
Phase 2 trial update on low dose radiation therapy for high-grade glioma (glioblastoma multiforme).
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CLINICAL_TRIALS trial_result · 2023-03-24Clinical Trial Update: A Study of Bempegaldesleukin (BEMPEG: NKTR-214) in Combination With Nivolumab in Children, Adolescents and Young Adults With Recurrent or Treatment-resistant Cancer [Phase 1, Phase 2]
A phase 1/2 trial evaluating bempegaldesleukin (BEMPEG) in combination with nivolumab in pediatric and young adult patients with recurrent o…
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CLINICAL_TRIALS trial_result · 2022-12-29Clinical Trial Update: Assessing 11C-Choline (11C-CH) PET to Distinguish True Tumor Progression From Pseudoprogression in High-grade Gliomas [NA]
Clinical trial investigating 11C-Choline PET to distinguish true tumor progression from pseudoprogression in high-grade gliomas has complete…
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CLINICAL_TRIALS trial_result · 2022-10-05Clinical Trial Update: Study of Dasatinib in Combination With Everolimus for Children and Young Adults With Gliomas Harboring Platelet-Derived Growth Factor Receptor (PDGFR) Alterations [Phase 2]
Phase 2 trial evaluating dasatinib with everolimus in pediatric and young adult gliomas with PDGFR alterations was terminated with posted re…
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CLINICAL_TRIALS trial_result · 2022-08-15Clinical Trial Update: Pilot Study of Cabozantinib for Recurrent or Progressive Central Nervous System Tumors in Children [Phase 2]
Phase 2 pilot study of cabozantinib for recurrent or progressive central nervous system tumors in children has been terminated; results were…
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CLINICAL_TRIALS trial_result · 2021-03-30Clinical Trial Update: A Study of Anlotinib in the Treatment of Recurrent High-grade Glioma [Phase 2]
Phase 2 trial update for Anlotinib in recurrent high-grade glioma.
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CLINICAL_TRIALS trial_result · 2020-11-05Clinical Trial Update: A Phase I/II Study of Ribociclib,a CDK4/6 Inhibitor, Following Radiation Therapy [Phase 1, Phase 2]
Phase I/II study of ribociclib (CDK4/6 inhibitor) following radiation therapy in high-grade glioma and DIPG was terminated; results posted.
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CLINICAL_TRIALS trial_result · 2020-10-19Clinical Trial Update: Neoadjuvant Carilizumab and Apatinib for Recurrent High-Grade Glioma [Phase 2]
Phase 2 clinical trial update exploring neoadjuvant Carilizumab and Apatinib for recurrent high-grade glioma.
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CLINICAL_TRIALS trial_result · 2020-06-04Clinical Trial Update: Long Term Survivors of High-grade Glioma and Their Caregivers
Clinical trial update on long-term survivors of high-grade glioma and their caregivers, with completed results and quality-of-life considera…
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CLINICAL_TRIALS trial_result · 2020-05-07Clinical Trial Update: Armodafinil in Reducing Cancer-Related Fatigue in Patients With High Grade Glioma [Phase 3]
Phase 3 trial evaluating armodafinil for reducing cancer-related fatigue in patients with high-grade glioma has completed and results have b…
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CLINICAL_TRIALS trial_result · 2020-02-05Clinical Trial Update: Clinical Study of Apatinib Combined With Temozolomide in the Treatment of Uncontrolled or Repeated High-grade Gliomas [Phase 2]
Phase 2 clinical trial investigating apatinib in combination with temozolomide for uncontrolled or recurrent high-grade gliomas.
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CLINICAL_TRIALS trial_result · 2019-08-08Clinical Trial Update: Photodynamic Therapy (PDT) For Recurrent High Grade Gliomas [Phase 2]
A Phase 2 trial of photodynamic therapy is reported for recurrent high-grade gliomas; the study has been terminated with results posted in 2…
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CLINICAL_TRIALS trial_result · 2019-07-24Clinical Trial Update: Safety and Efficacy Study of TH-302 CNS Penetration in Recurrent High Grade Astrocytoma Following Bevacizumab [Phase 2]
Phase 2 clinical trial updating safety and efficacy of TH-302 CNS penetration in recurrent high-grade astrocytoma after bevacizumab, complet…
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CLINICAL_TRIALS trial_result · 2019-07-23Clinical Trial Update: TMZ Plus Apatinib in Newly Diagnosed High-grade Glioma：RCT [Phase 2]
Phase 2 randomized trial investigating temozolomide plus apatinib in newly diagnosed high-grade glioma.
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CLINICAL_TRIALS trial_result · 2019-01-30Clinical Trial Update: Risk-Adapted Therapy for Young Children With Embryonal Brain Tumors, Choroid Plexus Carcinoma, High Grade Glioma or Ependymoma [Phase 2]
Phase 2 trial update on risk-adapted therapy for young children with embryonal brain tumors, choroid plexus carcinoma, high-grade glioma, or…
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CLINICAL_TRIALS trial_result · 2018-07-17Clinical Trial Update: Efficacy and Tolerability of Cisplatin Plus Alternating Weekly Temozolomide in Recurrent High-grade Gliomas [Phase 2]
Phase 2 trial evaluating cisplatin plus alternating weekly temozolomide shows efficacy and tolerability in patients with recurrent high-grad…
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CLINICAL_TRIALS trial_result · 2018-06-27Clinical Trial Update: Prospective Evaluation of T-cell Immune Status in Patients With Newly Diagnosed High Grade Gliomas [NA]
An update on a prospective clinical trial evaluating T-cell immune status in patients with newly diagnosed high-grade gliomas. The study sta…
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CLINICAL_TRIALS trial_result · 2018-05-18Clinical Trial Update: PET Imaging of High-grade Glioma Using 18F-fluoromethylcholine: a Tool for the Early Detection of Tumour Recurrence After Combined Radiochemotherapy? [Phase 1]
Phase 1 study evaluating PET imaging with 18F-fluoromethylcholine to detect early recurrence of high-grade glioma after radiochemotherapy.
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CLINICAL_TRIALS trial_result · 2018-05-02Clinical Trial Update: A Study of Bevacizumab Therapy in Patients With Newly Diagnosed High-Grade Gliomas and Diffuse Intrinsic Pontine Gliomas [EARLY_Phase 1]
This early-phase trial evaluated bevacizumab in patients with newly diagnosed high-grade gliomas and diffuse intrinsic pontine glioma; the s…
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CLINICAL_TRIALS trial_result · 2018-04-30Clinical Trial Update: Phase I/II: Decitabine/Vaccine Therapy in Relapsed/Refractory Pediatric High Grade Gliomas/Medulloblastomas/CNS PNETs [Phase 1, Phase 2]
Phase I/II trial of decitabine with a vaccine therapy in relapsed/refractory pediatric high-grade gliomas, medulloblastoma, and CNS primitiv…
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CLINICAL_TRIALS trial_result · 2018-01-04Clinical Trial Update: A Study of Apatinib in Recurrent or Recurrent High-grade Glioma [Phase 2]
Phase 2 trial investigating apatinib in patients with recurrent high-grade glioma.
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CLINICAL_TRIALS trial_result · 2017-12-13Clinical Trial Update: Antineoplaston Therapy in Treating Children With Recurrent or Refractory High-Grade Glioma [Phase 2]
Phase 2 trial of antineoplaston therapy in children with recurrent or refractory high-grade glioma was terminated, with results posted in 20…