High-grade Glioma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-04-11Clinical Trial Update: A Study of Chlorophyllin for the Management of Brain Radio-necrosis in Patients With Diffuse Glioma [Phase 2]
Phase 2 clinical trial evaluating chlorophyllin for the management of brain radionecrosis in patients with diffuse glioma is currently recru…
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CLINICAL_TRIALS research · 2025-04-09Clinical Trial Update: Injection of Active Allogeneic Natural Killer Cells in Patients With Gliomas [Phase 2]
A Phase 2 clinical trial evaluating injections of active allogeneic natural killer cells in patients with gliomas is currently recruiting.
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CLINICAL_TRIALS research · 2025-03-14Clinical Trial Update: Study of Sonodynamic Therapy in Participants with Recurrent High-Grade Glioma [EARLY_Phase 1]
An early-phase trial evaluating sonodynamic therapy for recurrent high-grade glioma is currently recruiting.
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CLINICAL_TRIALS research · 2025-03-13Clinical Trial Update: A Phase I Clinical Study of Intratumoral Injection GC001 in Patient With Recurrent or Progressive Gliomas [Phase 1]
Phase I study of intratumoral GC001 in patients with recurrent or progressive high-grade gliomas is currently recruiting.
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CLINICAL_TRIALS research · 2025-02-27Clinical Trial Update: Superselective Intra-arterial Cerebral Infusion of Temsirolimus in HGG [EARLY_Phase 1]
An early-phase (Phase 1) clinical trial is evaluating superselective intra-arterial cerebral infusion of temsirolimus for high-grade glioma,…
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CLINICAL_TRIALS research · 2025-02-21Clinical Trial Update: Study of Olutasidenib and Temozolomide in HGG [Phase 2]
Phase 2 study evaluating olutasidenib in combination with temozolomide for high-grade gliomas is currently recruiting.
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CLINICAL_TRIALS research · 2025-02-18Clinical Trial Update: Clinical Study of Carbon Ion Radiotherapy for High-grade Glioma [NA]
The trial is currently recruiting to evaluate carbon ion radiotherapy for high-grade glioma (heavy ion radiotherapy).
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CLINICAL_TRIALS research · 2025-02-05Clinical Trial Update: GD2-CAR T Cells for Pediatric Brain Tumours [Phase 1]
Phase 1 trial evaluating GD2-CAR T cells for pediatric brain tumors is currently recruiting. The study targets medulloblastoma, embryonal tu…
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CLINICAL_TRIALS research · 2024-12-24Clinical Trial Update: Bevacizumab Neoadjuvant Therapy for New High-grade Gliomas in the Brain [NA]
Bevacizumab is being studied as neoadjuvant therapy for new high-grade gliomas in the brain; the trial is currently recruiting.
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CLINICAL_TRIALS research · 2024-12-18Clinical Trial Update: Feasibility of Aspirate Tissue Monitoring in Neuro-oncological Surgery [NA]
The update notes a feasibility study evaluating aspirate tissue monitoring during neuro-oncological surgery for high-grade gliomas. The tria…
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CLINICAL_TRIALS research · 2024-12-16Clinical Trial Update: Surgical Suction Aspirates Fluorescence Measurement
A recruiting clinical trial at Kuopio University Hospital is evaluating fluorescence measurement of surgical suction aspirates in patients w…
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CLINICAL_TRIALS research · 2024-12-03Clinical Trial Update: FET PET in Differentiating Tumour Progression From Pseudoprogression in High Grade Glioma [Phase 2]
A Phase 2 clinical trial at Singapore General Hospital is evaluating FET PET imaging to differentiate tumor progression from pseudoprogressi…
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CLINICAL_TRIALS research · 2024-11-29Clinical Trial Update: Study of Safety and Pharmacokinetic Properties of Oral OKN-007 in Patients with Recurrent High-Grade Glioma [Phase 1]
Phase 1 study assessing safety and pharmacokinetics of oral OKN-007 in adults with recurrent high-grade glioma. The trial includes patients …
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CLINICAL_TRIALS research · 2024-11-29Clinical Trial Update: Recurrent High Grade Glioma Treated by LITT [NA]
A new clinical trial entry for recurrent high-grade glioma using laser interstitial thermal therapy (LITT) is currently recruiting at Beijin…
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CLINICAL_TRIALS research · 2024-08-06Clinical Trial Update: IDH1 and OCT4 in High Grade Astrocytoma
This clinical trial update indicates a study evaluating IDH1 and OCT4 in high-grade astrocytoma is currently recruiting.
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CLINICAL_TRIALS research · 2024-07-03Clinical Trial Update: Experiences and Needs of Patients With a High-grade Glioma and Their Caregivers
This clinical trial investigates the experiences and support needs of patients with high-grade glioma and their caregivers; the study is cur…
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CLINICAL_TRIALS research · 2024-05-08Clinical Trial Update: Adjuvant Dendritic Cell Immunotherapy for Pediatric Patients With High-grade Glioma or Diffuse Intrinsic Pontine Glioma [Phase 1, Phase 2]
Phase 1/2 trial evaluating adjuvant dendritic cell immunotherapy in pediatric high-grade glioma and diffuse intrinsic pontine glioma; the st…
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CLINICAL_TRIALS research · 2018-05-09Clinical Trial Update: Study of Tumor Metabolism by Isotopic Tagging in Patients With High-grade Glioma (CARBONOMIC) [Phase 1]
This is a terminated Phase 1 clinical trial update for CARBONOMIC, a study of tumor metabolism by isotopic tagging in patients with high-gra…
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CLINICAL_TRIALS research · 2017-06-16Clinical Trial Update: Apatinib and Irinotecan in Treating Patients With Recurrent High-grade Glioma [Phase 1, Phase 2]
This ClinicalTrials.gov entry reports a Phase 1/Phase 2 study evaluating the combination of apatinib and irinotecan for recurrent high-grade…
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CLINICAL_TRIALS research · 2017-04-05Clinical Trial Update: Differentiation of Progression From Treatment Effects in High-Grade Gliomas: A Clinical Trial With Multimodality MR Imaging
A clinical trial using multimodality MR imaging to distinguish progression from treatment effects in patients with high-grade glioma.
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CLINICAL_TRIALS research · 2017-02-20Clinical Trial Update: The Research on 89Zr-ABT806 PET Imaging in High Grade Glioma [NA]
Clinical trial update describing research on radiolabeled ABT-806 PET imaging with 89Zr in high-grade glioma, sponsored by Huashan Hospital.…
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CLINICAL_TRIALS research · 2013-12-30Clinical Trial Update: Permeability Map to Distinguish Progression From Pseudoprogression in High-Grade Glioma
Clinical trial evaluating a permeability-mapping imaging approach to distinguish progression from pseudoprogression in high-grade glioma. Sp…
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CLINICAL_TRIALS research · 2012-12-11Clinical Trial Update: Magnetic Resonance Imaging in Evaluating Response to RadiationTherapy in Patients With High Grade Glioma [NA]
This clinical trial investigates the use of MRI to evaluate response to radiation therapy in patients with high-grade glioma, and the study …