Hereditary Spastic Paraplegia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2026-06-05Clinical Trial Results: Single and Multiple Ascending Dose Study of MTR-601 in Healthy Individuals [Phase 1]
Phase 1 single and multiple ascending dose study of MTR-601 in healthy individuals with results posted after completion.
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CLINICAL_TRIALS trial_result · 2026-04-21Clinical Trial Update: D-Cycloserine for Serine Palmitoyltransferase Inhibition [Phase 4]
A Phase 4 trial evaluating D-Cycloserine as an inhibitor of Serine Palmitoyltransferase in hereditary spastic paraplegia has completed.
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CLINICAL_TRIALS trial_result · 2026-01-20Clinical Trial Update: Exoskeleton-assisted Neurorehabilitation [NA]
A completed clinical trial update on exoskeleton-assisted neurorehabilitation for stroke and spinal cord injury patients, with mentions of c…
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CLINICAL_TRIALS trial_result · 2025-09-02Clinical Trial Update: Therapeutic Metabolic Intervention in Patients With Spastic Paraplegia SPG5 [Phase 2]
Phase 2 clinical trial of a therapeutic metabolic intervention for hereditary spastic paraplegia SPG5 has completed; no results are provided…
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CLINICAL_TRIALS trial_result · 2025-04-28Clinical Trial Update: Safety and Efficacy of AAV9/AP4B1 (BFB-101) For Patients With AP4B1-related Hereditary Spastic Paraplegia Type 47 (SPG47) [Phase 1, Phase 2]
Phase 1/2 clinical trial assessing safety and efficacy of BFB-101, an AAV9-delivered AP4B1 gene therapy, for AP4B1-related Hereditary Spasti…
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CLINICAL_TRIALS trial_result · 2025-03-12Clinical Trial Update: Single and Multiple Ascending Dose Study of MTR-601 in Healthy Individuals [Phase 1]
A Phase 1 single- and multiple-ascending-dose study of MTR-601 in healthy individuals has completed, assessing safety and pharmacokinetics a…
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CLINICAL_TRIALS trial_result · 2025-02-04Clinical Trial Update: SPATAX: Clinical and Genetic Analysis of Cerebellar Ataxias and Spastic Paraplegias
The SPATAX study, a clinical and genetic analysis of cerebellar ataxias and spastic paraplegias, has completed.
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CLINICAL_TRIALS trial_result · 2021-09-27Clinical Trial Update: Repetitive Transcranial Magnetic Stimulation as Therapy in Hereditary Spastic Paraplegia and Adrenomyeloneuropathy [NA]
A completed clinical trial investigating repetitive transcranial magnetic stimulation as a therapy for hereditary spastic paraplegia and adr…
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CLINICAL_TRIALS trial_result · 2019-05-23Clinical Trial Update: Physiotherapy in Hereditary Spastic Paraplegia [Phase 2]
Phase 2 clinical trial assessing physiotherapy in hereditary spastic paraplegia has been completed.
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CLINICAL_TRIALS trial_result · 2017-11-07Clinical Trial Update: Effects of Botulinum Toxin Injections in Patients With Hereditary Spastic Paraplegia [Phase 2, Phase 3]
Phase 2/3 trial assessing botulinum toxin injections in patients with hereditary spastic paraplegia has completed.
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CLINICAL_TRIALS trial_result · 2016-06-03Clinical Trial Update: Validation of Biomarkers in Amyotrophic Lateral Sclerosis (ALS)
The clinical trial completed a study validating biomarkers in amyotrophic lateral sclerosis and related motor neuron diseases, evaluating ca…
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CLINICAL_TRIALS trial_result · 2008-03-04Clinical Trial Update: Nuclear Magnetic Spectroscopy Imaging to Evaluate Primary Lateral Sclerosis, Hereditary Spastic Paraplegia and Amyotrophic Lateral Sclerosis
A completed clinical trial evaluating nuclear magnetic spectroscopy imaging for Primary Lateral Sclerosis, Hereditary Spastic Paraplegia, an…