Hepatic Encephalopathy
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2016-11-11Clinical Trial Update: Randomised Controlled Trial of Mechanistic Effects of Rifaximin in Cirrhosis and Chronic Hepatic Encephalopathy [Phase 4]
A Phase 4 randomized controlled trial studying the mechanistic effects of rifaximin in liver cirrhosis with hepatic encephalopathy has compl…
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CLINICAL_TRIALS research · 2016-10-12Clinical Trial Update: A RCT COMPARING LACTULOSE AND RIFAXIMIN ASSOCIATED WITH A VEGETABLE DIET IN THE PREVENTION OF POST-TIPS OVERT HEPATIC ENCEPHALOPATHY [Phase 1, Phase 2]
A Phase 1/2 randomized trial comparing lactulose and rifaximin (with a vegetable diet) to prevent post-TIPS hepatic encephalopathy in cirrho…
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CLINICAL_TRIALS trial_result · 2016-09-07Clinical Trial Update: iPod Games in Hepatic Encephalopathy [NA]
A completed clinical trial investigating whether iPod games affect outcomes in patients with hepatic encephalopathy and cirrhosis.
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CLINICAL_TRIALS trial_result · 2016-08-18Clinical Trial Update: Effect of Midodrine and Albumine in the Prevention of Complications in Cirrhotic Patients Awaiting Liver Transplantation [Phase 4]
A Phase 4 clinical trial evaluated midodrine plus albumin to prevent complications in patients with liver cirrhosis awaiting transplantation…
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CLINICAL_TRIALS research · 2016-08-08Clinical Trial Update: Timing of Acute Palliative Care Consultation in Critically Ill Patients [NA]
Clinical trial NCT02858778 from Wayne State University investigates the timing of acute palliative care consultation in critically ill patie…
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CLINICAL_TRIALS trial_result · 2016-07-28Clinical Trial Update: N-acetylcysteine in Non-Acetaminophen Pediatric Acute Liver Failure [Phase 3]
Phase 3 clinical trial update for N-acetylcysteine in non-acetaminophen pediatric acute liver failure. The study has completed and results w…
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CLINICAL_TRIALS trial_result · 2016-06-08Clinical Trial Update: Fructans, Lactitol and Lactose in Minimal Hepatic Encephalopathy [NA]
A clinical trial evaluating fructans, lactitol, and lactose for minimal hepatic encephalopathy in patients with liver cirrhosis has complete…
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CLINICAL_TRIALS trial_result · 2016-03-31Clinical Trial Update: Efficacy and Safety Study of Ammonul® in Patients With Grade 3 or 4 Hepatic Encephalopathy [Phase 2]
A Phase 2 efficacy and safety study of Ammonul in patients with grade 3 or 4 hepatic encephalopathy was terminated, with results posted in 2…
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CLINICAL_TRIALS withdrawal · 2016-03-11Clinical Trial Update: Effect of Music on Attention and Prospective Memory in Hepatic Encephalopathy
A clinical trial evaluating the effect of music on attention and prospective memory in hepatic encephalopathy and cirrhosis has been withdra…
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CLINICAL_TRIALS withdrawal · 2016-03-02Clinical Trial Update: A Randomized Comparison of Rifaximin Versus Lactulose in Hospitalized Cirrhotic Patients With Renal Failure [Phase 3]
A Phase 3 randomized trial comparing rifaximin versus lactulose in hospitalized cirrhotic patients with renal failure has been withdrawn.
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CLINICAL_TRIALS trial_result · 2016-02-23Clinical Trial Update: Diagnosis of Covert/Minimal Hepatic Encephalopathy by Means of Continuous Reaction Time Measurement [NA]
A completed clinical trial evaluated continuous reaction-time measurement as a diagnostic tool for covert/minimal hepatic encephalopathy in …
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CLINICAL_TRIALS trial_result · 2016-01-12Clinical Trial Update: A Multi-Center Group to Study Acute Liver Failure in Children
A multi-center study investigating acute liver failure and hepatic encephalopathy in children has completed.
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CLINICAL_TRIALS trial_result · 2015-12-22Clinical Trial Update: Monitoring of Encephalopathy in Cirrhotic Patients Admitted in Intensive Care
This clinical trial update shows that the study examining monitoring of hepatic encephalopathy in cirrhotic patients admitted to intensive c…
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CLINICAL_TRIALS trial_result · 2015-10-27Clinical Trial Update: Effect of Transjugular Intrahepatic Portosystemic Shunt on Gut Microbiota in Cirrhotic Patients
This clinical trial update describes the investigation of the Transjugular Intrahepatic Portosystemic Shunt (TIPS) and its effect on gut mic…
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CLINICAL_TRIALS trial_result · 2015-10-22Clinical Trial Update: Brain Muscle Axis During Treatment of Hepatic Encephalopathy With L-ornithine L-aspartate [Phase 4]
Phase 4 clinical trial evaluating L-ornithine L-aspartate for hepatic encephalopathy has completed. The update covers results from patients …
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CLINICAL_TRIALS trial_result · 2015-09-30Clinical Trial Update: A Study of Safety and Efficacy of HPN-100 in Subjects With Cirrhosis and Episodic Hepatic Encephalopathy [Phase 2]
A Phase 2 study evaluating the safety and efficacy of HPN-100 in subjects with liver cirrhosis and episodic hepatic encephalopathy has compl…
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CLINICAL_TRIALS withdrawal · 2015-08-04Clinical Trial Update: The Effect of a Large-volume Paracentesis on Fatigue, Sleep, and Quality of Life in Cirrhosis
A study investigating the impact of large-volume paracentesis on fatigue, sleep, and quality of life in cirrhosis has been withdrawn.
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CLINICAL_TRIALS trial_result · 2015-06-12Clinical Trial Update: Metformin Experience on Minimal Hepatic Encephalopathy [Phase 4]
A Phase 4 clinical trial evaluating metformin for minimal hepatic encephalopathy in liver cirrhosis; the current status is unknown.
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CLINICAL_TRIALS trial_result · 2015-05-29Clinical Trial Update: Brain Imaging in Patients With Chronic Liver Disease and Functional Impairment. [NA]
A completed clinical trial investigating brain imaging in patients with chronic liver disease and functional impairment due to cirrhosis and…
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CLINICAL_TRIALS trial_result · 2015-05-25Clinical Trial Update: Default Mode Network fMRI Maps as a Predictive Index of Hepatic Encephalopathy Outcome
Completed clinical trial evaluating whether resting-state default mode network fMRI maps can predict outcomes in hepatic encephalopathy rela…
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CLINICAL_TRIALS withdrawal · 2015-05-12Clinical Trial Update: Hepatic Encephalopathy: Lactulose or Polyethylene Glycol (H.E.L.P.) [NA]
A clinical trial evaluating lactulose versus polyethylene glycol for hepatic encephalopathy has been withdrawn.
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FDA approval · 2015-03-27FDA Approved: LACTULOSE — Original Application (APOZEAL PHARMACEUTICALS INC)
FDA approved the original application for lactulose from ApoZeal Pharmaceuticals Inc, enabling generic lactulose products for constipation a…
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CLINICAL_TRIALS trial_result · 2015-02-25Clinical Trial Update: Single Pass Albumin Dialysis in Patients With Cirrhosis [Phase 1, Phase 2]
Clinical trial update indicating completion of Phase 1 and Phase 2 studies of Single Pass Albumin Dialysis in patients with cirrhosis and re…
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CLINICAL_TRIALS research · 2015-01-08Clinical Trial Update: The Effects of Nitazoxanide in Hepatic Encephalopathy [Phase 2]
This document reports an ongoing Phase 2 clinical trial evaluating nitazoxanide for hepatic encephalopathy, sponsored by Ain Shams Universit…
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CLINICAL_TRIALS trial_result · 2014-12-11Clinical Trial Update: Efficacy Study of Polyethylene Glycol 3350-electrolyte Solution (GoLYTELY®) Versus Lactulose in Patients With Hepatic Encephalopathy. [NA]
A completed clinical trial comparing GoLYTELY (polyethylene glycol 3350-electrolyte solution) with lactulose in hepatic encephalopathy, with…