Hepatic Encephalopathy
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2014-11-18Clinical Trial Update: Bioelectrical Impedance Vector Analysis in Cirrhotic Patients
A completed clinical trial evaluating Bioelectrical Impedance Vector Analysis in patients with cirrhosis and hepatic encephalopathy.
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CLINICAL_TRIALS trial_result · 2014-08-20Clinical Trial Update: Comparison Between Lactulose and Lactulose-Paraffin in Cirrhotic Patients [Phase 2]
Phase 2 trial comparing lactulose to lactulose-paraffin in patients with cirrhosis and hepatic encephalopathy has completed.
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CLINICAL_TRIALS research · 2014-06-30Clinical Trial Update: Quantitative Determination of Brain Water Content in Patients During and After Hepatic Encepalopathy
Clinical trial update focusing on measuring brain water content in patients during and after hepatic encephalopathy.
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CLINICAL_TRIALS trial_result · 2014-06-24Clinical Trial Update: Acetyl-L-Carnitine Reduces Perceived Work Stress and Improves Work Ability and Work Performance in Hepatic Encephalopathy [Phase 3]
Phase 3 trial evaluating acetyl-L-carnitine in hepatic encephalopathy reports reductions in perceived work stress and improvements in work a…
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CLINICAL_TRIALS trial_result · 2014-06-18Clinical Trial Update: AST-120 Used to Treat Mild Hepatic Encephalopathy [Phase 2]
A Phase 2 clinical trial evaluating AST-120 for hepatic encephalopathy has completed.
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CLINICAL_TRIALS trial_result · 2014-05-30Clinical Trial Update: Safety and Efficacy of AST-120 Compared to Lactulose in Patients With Hepatic Encephalopathy [Phase 2]
A Phase 2 trial comparing AST-120 with lactulose in hepatic encephalopathy to assess safety and efficacy. The study has completed.
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FDA approval · 2014-03-12FDA Approved: XIFAXAN — Supplemental Application (Salix Pharmaceuticals, Inc.)
The FDA approved a supplemental application for XIFAXAN (rifaximin) filed by Salix Pharmaceuticals, Inc., resulting in an update to the prod…
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CLINICAL_TRIALS trial_result · 2014-02-07Clinical Trial Update: Effect of Tolvaptan on Cognitive Function in Cirrhosis [Phase 3]
A Phase 3 trial evaluating tolvaptan for cognitive function in patients with cirrhosis and hepatic encephalopathy, including cases associate…
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CLINICAL_TRIALS trial_result · 2014-01-07Clinical Trial Update: Probiotic Lactobacillus GG (LGG) in Patients With Minimal Hepatic Encephalopathy [Phase 1]
Phase 1 clinical trial evaluating probiotic Lactobacillus GG for minimal hepatic encephalopathy has completed.
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CLINICAL_TRIALS research · 2014-01-07Clinical Trial Update: Efficacy of Sildenafil in the Improvement of Cognition and Quality of Life in Patients With Cirrhosis of Liver. A Proof of Concept Study. [Phase 1, Phase 2]
This clinical trial update describes a proof-of-concept study evaluating sildenafil for cognition and quality of life in patients with cirrh…
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CLINICAL_TRIALS trial_result · 2013-12-30Clinical Trial Update: Secondary Prophylaxis of Hepatic Encephalopathy With a Probiotic Preparation [Phase 2, Phase 3]
Clinical trial update on a probiotic preparation for secondary prophylaxis of hepatic encephalopathy in Phase 2 and Phase 3, with the studie…
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CLINICAL_TRIALS trial_result · 2013-12-17Clinical Trial Update: Post Transjugular Intrahepatic Portosystemic Shunt (Tips) Albumine Infusion to Prevent Hepatic Encephalopathy [Phase 4]
Phase 4 trial evaluating post-TIPS albumin infusion to prevent hepatic encephalopathy has completed.
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CLINICAL_TRIALS trial_result · 2013-09-23Clinical Trial Update: Quality of Life and Nutritional Improvements in Cirrhotic Patients [Phase 4]
Phase 4 clinical trial assessing quality of life and nutritional improvements in patients with liver cirrhosis, hepatic encephalopathy, and …
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CLINICAL_TRIALS trial_result · 2013-06-14Clinical Trial Update: Neuromonitoring of Hepatic Encephalopathy
A University of Helsinki-sponsored clinical trial evaluating neuromonitoring in hepatic encephalopathy related to acute liver failure has co…
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CLINICAL_TRIALS trial_result · 2013-06-04Clinical Trial Update: Effect of Probiotics in Treatment of Minimal Hepatic Encephalopathy (MHE) and Health Related Quality of Life [Phase 2, Phase 3]
A completed Phase 2/3 clinical trial evaluating probiotics for minimal hepatic encephalopathy and health-related quality of life. The study …
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CLINICAL_TRIALS trial_result · 2013-04-04Clinical Trial Update: Rifaximin Plus Lactulose Versus Lactulose Alone for the Treatment of Hepatic Encephalopathy: a Double Blind Randomized Trial [NA]
A double-blind randomized trial comparing rifaximin plus lactulose versus lactulose alone for hepatic encephalopathy has completed.
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CLINICAL_TRIALS trial_result · 2013-03-20Clinical Trial Update: A Study of Controlled Lactulose Withdrawal [NA]
This entry reports the completion of a clinical study examining controlled withdrawal of lactulose in patients with hepatic encephalopathy.
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CLINICAL_TRIALS research · 2013-02-25Clinical Trial Update: ETOS: Minimal Hepatic Encephalopathy in Childhood and Young Adult: epidemiOlogical Study and Pilot Interventional Study [Phase 3]
ETOS is a Phase 3 clinical trial investigating minimal hepatic encephalopathy in children and young adults, including epidemiological and pi…
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CLINICAL_TRIALS trial_result · 2012-12-17Clinical Trial Update: Efficacy of Albumin for Acute Encephalopathy in Patients With Cirrhosis [Phase 4]
A Phase 4 trial completed evaluating albumin for acute hepatic encephalopathy in patients with cirrhosis, reporting on its efficacy.
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CLINICAL_TRIALS trial_result · 2012-06-19Clinical Trial Update: Cerebral Oxygen, Blood Flow and Ammonia Uptake in Patients With Cirrhosis and an Acute Episode of Hepatic Encephalopathy (HE)
A completed clinical trial evaluating cerebral oxygenation, cerebral blood flow, and ammonia uptake in patients with cirrhosis and an acute …
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CLINICAL_TRIALS trial_result · 2012-05-21Clinical Trial Update: Cerebrovascular Reactivity in Hepatic Encephalopathy
The clinical trial studying cerebrovascular reactivity in hepatic encephalopathy has completed. The provided snippet does not include result…
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CLINICAL_TRIALS trial_result · 2012-04-10Clinical Trial Update: S. Endotoxin, Inflammatory Mediators and MRS Before and After Treatment in MHE [NA]
The study investigates endotoxin levels, inflammatory mediators, and MR spectroscopy before and after treatment in hepatic encephalopathy; t…
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FDA approval · 2012-01-25FDA Approved: ENULOSE — Original Application (Actavis Pharma, Inc.)
FDA approved the original ANDA for Enulose (lactulose) by Actavis Pharma, establishing a generic lactulose product.
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FDA approval · 2012-01-25FDA Approved: CONSTULOSE — Original Application (Actavis Pharma, Inc.)
FDA approved Actavis Pharma, Inc.'s CONSTULOSE as an original generic application for lactulose. Lactulose is used as a laxative for constip…
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CLINICAL_TRIALS research · 2011-09-14Clinical Trial Update: Prediction of Mortality in Patients Waiting for Liver Transplantation Through Brain Magnetic Resonance Imaging
This clinical trial explores using brain MRI to predict mortality in patients with end-stage liver disease waiting for liver transplantation…