Hepatic Encephalopathy
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2019-09-17Clinical Trial Update: RICE Trial: Rifaximin In Chronic Hepatic Encephalopathy - A Randomized, Controlled Trial [Phase 3]
Phase 3 randomized trial evaluating rifaximin for hepatic encephalopathy; trial terminated with posted results in 2019.
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CLINICAL_TRIALS trial_result · 2019-09-09Clinical Trial Update: The Safety/Efficacy of Rifaximin With/Without Lactulose in Participants With A History of Recurrent Hepatic Encephalopathy [Phase 4]
Phase 4 trial assessing safety and efficacy of rifaximin with or without lactulose in participants with a history of recurrent hepatic encep…
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CLINICAL_TRIALS trial_result · 2019-08-14Clinical Trial Update: Safety and Tolerability Study of Rifaximin in Participants With a History of Hepatic Encephalopathy [Phase 3]
Phase 3 safety and tolerability trial of rifaximin in participants with a history of hepatic encephalopathy has completed; results posted.
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CLINICAL_TRIALS trial_result · 2019-08-14Clinical Trial Update: A 6-month Efficacy, Safety, and Tolerability Study of Rifaximin In Preventing Hepatic Encephalopathy [Phase 3]
A Phase 3 clinical trial evaluating rifaximin for prevention of hepatic encephalopathy reports completed with posted results.
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CLINICAL_TRIALS trial_result · 2019-06-17Clinical Trial Update: PEG3350 in ACLF With Hepatic Encephalopathy [Phase 4]
Clinical trial update for PEG3350 in acute-on-chronic liver failure with hepatic encephalopathy (Phase 4) is ongoing with an unknown status.
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CLINICAL_TRIALS trial_result · 2019-04-09Clinical Trial Update: Effect of Rifaximine on Sleep Disorders in Patients Suffering From Hepatic Encephalopathy [NA]
Clinical trial updating the effects of rifaximin on sleep disorders in patients with hepatic encephalopathy; study completed with results po…
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FDA approval · 2018-11-23FDA Approved: LACTULOSE — Original Application (Chartwell RX, LLC)
FDA approves Lactulose from Chartwell RX, LLC under ANDA209517; a generic formulation indicated for constipation and hepatic encephalopathy.
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FDA approval · 2018-06-11FDA Approved: LACTULOSE — Original Application (APOZEAL PHARMACEUTICALS INC)
FDA approved Lactulose under an original application from Apozeal Pharmaceuticals Inc.
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CLINICAL_TRIALS trial_result · 2018-05-22Clinical Trial Update: Lactulose, L-ornithine L-aspartate, or Rifaximin Versus Placebo for Preventing Hepatic Encephalopathy in Variceal Bleeding [Phase 4]
Phase 4 clinical trial comparing lactulose, L-ornithine L-aspartate, and rifaximin against placebo to prevent hepatic encephalopathy in pati…
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CLINICAL_TRIALS research · 2018-02-28Clinical Trial Update: To Compare Efficacy and Safety of Lactulose Versus Polyethylene Glycol for Treatment of Overt Hepatic Encephalopathy in Cirrhotics. [NA]
A clinical trial update comparing lactulose with polyethylene glycol for overt hepatic encephalopathy in patients with cirrhosis; current st…
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CLINICAL_TRIALS trial_result · 2017-12-28Clinical Trial Update: Albumin Infusion Effects in Mortality in Patients With Cirrhosis and Hepatic Encephalopathy [Phase 4]
Phase 4 trial investigating albumin infusion effects on mortality in patients with cirrhosis and hepatic encephalopathy.
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CLINICAL_TRIALS research · 2017-12-13Clinical Trial Update: Diet Management on Hepatic Encephalopathy of Patients With Variceal Bleeding After Intrahepatic Portosystemic Shunt Creation [NA]
This clinical trial update discusses diet management for hepatic encephalopathy in patients who have undergone intrahepatic portosystemic sh…
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CLINICAL_TRIALS research · 2017-10-11Clinical Trial Update: Plasma Free Amino Acids in Patients With Hepatic Encephalopathy
This document reports a clinical trial investigating plasma free amino acids in patients with hepatic encephalopathy; no results or status d…
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CLINICAL_TRIALS trial_result · 2017-08-22Clinical Trial Update: Study on B-blockers to Prevent Decompensation of Cirrhosis With HTPortal [Phase 4]
Phase 4 clinical trial evaluating non-selective beta-blockers to prevent decompensation in cirrhosis with portal hypertension has completed.
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CLINICAL_TRIALS trial_result · 2017-08-22Clinical Trial Update: Autoregulation Assessment During Liver Transplantation
This is an update of a completed clinical trial evaluating autoregulation during liver transplantation.
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CLINICAL_TRIALS research · 2017-08-21Clinical Trial Update: Nitazoxanide Plus Lactulose Versus Lactulose Alone Treatment of Hepatic Encephalopathy [Phase 2, Phase 3]
Phase 2/3 trial comparing nitazoxanide plus lactulose versus lactulose alone for hepatic encephalopathy. The status of the study is unknown.
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CLINICAL_TRIALS trial_result · 2017-08-04Clinical Trial Update: The Role of Bacterial Overgrowth and Delayed Intestinal Transit in Hepatic Encephalopathy. [NA]
Clinical trial evaluating the role of small intestinal bacterial overgrowth and delayed intestinal transit in hepatic encephalopathy; the st…
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CLINICAL_TRIALS research · 2017-07-31Clinical Trial Update: The International Imaging Registry in Liver Cirrhosis (BAVENO-VI SPSS GROUP).
Clinical trial registry update for the International Imaging Registry in Liver Cirrhosis (BAVENO-VI SPSS GROUP), listing conditions includin…
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CLINICAL_TRIALS trial_result · 2017-05-11Clinical Trial Update: Feasibility of Critical Flicker Frequency Procedure for the Diagnosis of Minimal Encephalopathy [NA]
This clinical trial update reports on the feasibility of using the critical flicker frequency procedure to diagnose minimal hepatic encephal…
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CLINICAL_TRIALS trial_result · 2017-05-11Clinical Trial Update: Minimal HePatic Encephalopathy Among CiRrhotics. A Cross SEctional, Clinico-EpidEmiological, Multi-Centre, Study in Patients of PakisTan
A completed cross-sectional, multicenter study in Pakistan evaluating minimal hepatic encephalopathy in patients with cirrhosis.
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CLINICAL_TRIALS trial_result · 2017-04-27Clinical Trial Update: PEG (Polyethylene Glycol)Versus Lactulose For Treatment Of Overt Hepatic Encephalopathy [Phase 4]
Phase 4 clinical trial comparing polyethylene glycol (PEG) to lactulose for treatment of overt hepatic encephalopathy. Status is currently u…
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CLINICAL_TRIALS research · 2017-04-17Clinical Trial Update: Glutamine Challenge as Predictor of Hepatic Encephalopathy After Transjugular Intrahepatic Portosystemic Shunt (TIPS)
This clinical trial update describes a terminated study investigating whether a glutamine challenge can predict hepatic encephalopathy after…
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CLINICAL_TRIALS trial_result · 2017-02-08Clinical Trial Update: L-ornithine L-aspartate in Overt Hepatic Encephalopathy [Phase 4]
This update reports completion of a Phase 4 trial evaluating L-ornithine L-aspartate for overt hepatic encephalopathy in patients with cirrh…
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CLINICAL_TRIALS other · 2017-01-25Clinical Trial Update: Factors Associated With End Stage Liver Disease
This clinical trial update notes that NCT01846819, sponsored by NYU Langone Health, investigating factors associated with end-stage liver di…
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CLINICAL_TRIALS trial_result · 2016-11-23Clinical Trial Update: Evaluation of Probiotics in the Treatment of Portal Hypertension [NA]
The trial update notes the completion of a study evaluating probiotics for portal hypertension in patients with liver cirrhosis, portal hype…