Hepatic Encephalopathy
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Sign up freeTop drugs studied for this disease
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FDA approval · 2026-04-14FDA Approved: KRISTALOSE — Supplemental Application (Cumberland Pharmaceuticals Inc.)
The FDA approved a supplemental application for Kristalose (lactulose) from Cumberland Pharmaceuticals Inc.
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CLINICAL_TRIALS research · 2026-04-14Clinical Trial Update: Microbiota trAnSplant ThERaPy In hEpatiC Encephalopathy (MASTERPIECE) [Phase 2]
Phase 2 clinical trial MASTERPIECE evaluating microbiota transplant therapy for hepatic encephalopathy in cirrhosis; currently not yet recru…
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CLINICAL_TRIALS trial_result · 2026-04-09Clinical Trial Update: Apixaban-PK Trial: Preventing Portal Hypertension Complications in Cirrhosis [Phase 4]
Phase 4 pharmacokinetic study of apixaban to prevent portal hypertension complications in cirrhosis is currently recruiting.
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CLINICAL_TRIALS research · 2026-04-08Clinical Trial Update: Hepatic Encephalopathy and Albumin Lasting Cognitive Improvement [Phase 2]
A Phase 2 clinical trial is evaluating whether albumin provides lasting cognitive improvement in patients with cirrhosis and hepatic encepha…
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CLINICAL_TRIALS trial_result · 2026-03-18Clinical Trial Update: Efficacy and Safety of Lemborexant for Patients With Cirrhosis and Sleep Problems [Phase 2]
Phase 2 trial evaluating the efficacy and safety of lemborexant for sleep problems in patients with liver cirrhosis; the study status is com…
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CLINICAL_TRIALS research · 2026-03-10Clinical Trial Update: TReatment for ImmUne Mediated PathopHysiology [Phase 2]
A Phase 2 clinical trial sponsored by the National Institute of Diabetes and Digestive and Kidney Diseases is recruiting to treat immune-med…
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CLINICAL_TRIALS research · 2026-03-06Clinical Trial Update: Evaluation of the Outcome of Fecal Microbiota Transplantation [Phase 1, Phase 2]
Clinical trial registry entry describing a Phase 1/2 study evaluating fecal microbiota transplantation for hepatic encephalopathy, sponsored…
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CLINICAL_TRIALS research · 2026-02-27Clinical Trial Update: Clinical Efficacy and Survival Prediction Analysis of Transjugular Intrahepatic Portosystemic Shunt in Patients With Liver Cirrhosis
This clinical trial update analyzes the efficacy and survival prediction of transjugular intrahepatic portosystemic shunt (TIPS) in patients…
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CLINICAL_TRIALS research · 2026-02-24Clinical Trial Update: EGEN-5784 Porcine Liver With the Metra® ELC Device [Phase 1]
Phase 1 trial update for EGEN-5784 porcine liver with the Metra ELC device, evaluating use in acute-on-chronic liver failure and hepatic enc…
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CLINICAL_TRIALS research · 2026-02-18Clinical Trial Update: Development of a Cognitive Tool for Rapid and Reliable Screening of Minimal Hepatic Encephalopathy: Pilot Study
Pilot study update on developing a cognitive screening tool for rapid and reliable detection of minimal hepatic encephalopathy in patients w…
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CLINICAL_TRIALS trial_result · 2026-02-18Clinical Trial Update: The Liver Cirrhosis Cognitive Decline Scale (LiCCoS)
The Liver Cirrhosis Cognitive Decline Scale (LiCCoS) is the subject of a recruiting clinical trial investigating cognitive dysfunction in pa…
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CLINICAL_TRIALS research · 2026-01-30Clinical Trial Update: Pilot Open-Label Trial of Resistant Potato Starch in Patients With Cirrhosis and Overt Hepatic Encephalopathy [NA]
A pilot open-label clinical trial is evaluating resistant potato starch for patients with cirrhosis and overt hepatic encephalopathy and is …
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CLINICAL_TRIALS research · 2026-01-20Clinical Trial Update: Underdilated-stent Technique Improves Post-TIPS Encephalopathy [NA]
A clinical trial update shows recruitment for a study evaluating an underdilated-stent technique to improve post-TIPS hepatic encephalopathy…
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CLINICAL_TRIALS trial_result · 2026-01-12Clinical Trial Update: A Study to See if an Investigational Medicine Called VS-01 Can Help and How Safe it is in the Treatment of Patients With Overt Hepatic Encephalopathy [Phase 2]
Genfit's Phase 2 trial of the investigational medicine VS-01 for hepatic encephalopathy in patients with acute-on-chronic liver failure and …
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CLINICAL_TRIALS research · 2025-12-31Clinical Trial Update: Fecal Microbiota Transplant as Treatment of Hepatic Encephalopathy [Phase 2]
A Phase 2 clinical trial is evaluating fecal microbiota transplant as a treatment for hepatic encephalopathy; the study is currently active …
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CLINICAL_TRIALS research · 2025-12-09Clinical Trial Update: UDCA to Prevent Post-TIPS Hepatic Encephalopathy [NA]
A clinical trial is evaluating whether ursodeoxycholic acid can prevent hepatic encephalopathy after a transjugular intrahepatic portosystem…
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CLINICAL_TRIALS research · 2025-11-25Clinical Trial Update: Late Evening and Early Morning Protein Supplement to Reduce Readmissions for Hepatic Encephalopathy [NA]
This clinical trial is evaluating whether a late-evening and early-morning protein supplement can reduce readmissions in patients with hepat…
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CLINICAL_TRIALS research · 2025-09-25Clinical Trial Update: VICIS - Vienna Cirrhosis Study
This is an update on the VICIS Vienna Cirrhosis Study. The multicenter trial led by the Medical University of Vienna is currently recruiting…
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CLINICAL_TRIALS research · 2025-09-25Clinical Trial Update: Study on Proteomic and Microbiome Changes in Patients With Hepatic Encephalopathy (HE)
A clinical trial update describing a study on proteomic and microbiome changes in patients with hepatic encephalopathy, sponsored by The Fir…
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CLINICAL_TRIALS research · 2025-09-10Clinical Trial Update: Evaluation of Rifaximin SSD for Delaying Encephalopathy Decompensation in Patients With Cirrhosis [Phase 3]
A Phase 3 trial evaluating rifaximin SSD to delay hepatic encephalopathy decompensation in cirrhosis is currently active but not recruiting.
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CLINICAL_TRIALS trial_result · 2025-09-02Clinical Trial Update: Efficacy and Safety of Nifuroxazide in the Treatment of Hepatic Encephalopathy in Egyptian Patients With Liver Cirrhosis [Phase 3]
A Phase 3 trial evaluating the efficacy and safety of nifuroxazide for hepatic encephalopathy in patients with liver cirrhosis has completed…
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CLINICAL_TRIALS research · 2025-08-28Clinical Trial Update: Affect of Melatonin on Sleep and Cognition in Cirrhosis [NA]
This clinical trial is recruiting to assess whether melatonin improves sleep and cognitive function in people with hepatic encephalopathy re…
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CLINICAL_TRIALS research · 2025-08-26Clinical Trial Update: Human Albumin Infusion in Liver Cirrhosis and Overt Hepatic Encephalopathy (HACHE) [NA]
A clinical trial evaluating human albumin infusion for patients with liver cirrhosis and overt hepatic encephalopathy is currently recruitin…
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CLINICAL_TRIALS research · 2025-07-24Clinical Trial Update: Study to Assess Rifaximin Soluble Solid Dispersion (SSD) for the Delay of Encephalopathy Decompensation in Cirrhosis [Phase 3]
Phase 3 study evaluating rifaximin soluble solid dispersion to delay hepatic encephalopathy decompensation in patients with cirrhosis, spons…
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CLINICAL_TRIALS research · 2025-07-24Clinical Trial Update: Mechanisms of Perioperative Systemic Inflammation in the Development of PND in Cirrhotic Patients
A clinical trial from Sichuan Provincial People's Hospital investigates how perioperative systemic inflammation may contribute to postoperat…