Head and Neck Squamous Cell Carcinoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-04-09Clinical Trial Update: A Study of Ficlatuzumab in Combination With Cetuximab in Participants With Recurrent or Metastatic (R/M) HPV Negative Head and Neck Squamous Cell Carcinoma [Phase 3]
This is a Phase 3 clinical trial evaluating ficlatuzumab plus cetuximab in patients with recurrent or metastatic HPV-negative head and neck …
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CLINICAL_TRIALS trial_result · 2026-04-09Clinical Trial Update: Safety, PK and Efficacy of AI-061 in Advanced Solid Tumors [Phase 1]
Phase 1 update reporting safety, pharmacokinetics, and preliminary efficacy data for AI-061 in advanced solid tumors across multiple indicat…
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CLINICAL_TRIALS research · 2026-04-09Clinical Trial Update: Combined Amivantamab, Carboplatin and Paclitaxel in Unresectable Locally Recurrent or Metastatic Head and Neck Cancer [Phase 2]
This update describes a Phase 2 clinical trial evaluating the combination of amivantamab with carboplatin and paclitaxel for unresectable lo…
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CLINICAL_TRIALS trial_result · 2026-04-09Clinical Trial Update: A Study of Pembrolizumab in Combination With Chemotherapy for Head and Neck Cancer [Phase 2]
Phase 2 study of pembrolizumab in combination with chemotherapy for head and neck squamous cell carcinoma is currently suspended.
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CLINICAL_TRIALS research · 2026-04-09Clinical Trial Update: Neoadjuvant Immunoradiotherapy in Head & Neck Cancer (NIRT 2-HNC) [Phase 2]
Phase 2 neoadjuvant immunoradiotherapy trial for head and neck cancer is currently active but not recruiting.
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CLINICAL_TRIALS research · 2026-04-09Clinical Trial Update: 5-Fluorouracil Response and Optimization STudy (The FROST Trial) [Phase 2]
Phase 2 trial update for the FROST study evaluating 5-fluorouracil in head and neck cancers. The trial is currently not recruiting and inclu…
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CLINICAL_TRIALS trial_result · 2026-04-08Clinical Trial Update: IO102-IO103 in Combination With Pembrolizumab as First-line Treatment for Patients With Metastatic NSCLC, SCCHN, or mUBC [Phase 2]
Phase 2 trial results of IO102-IO103 in combination with pembrolizumab as first-line therapy for metastatic non-small cell lung cancer, head…
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CLINICAL_TRIALS trial_result · 2026-04-08Clinical Trial Update: GEN1042 Safety Trial and Anti-tumor Activity in Participants With Malignant Solid Tumors [Phase 1, Phase 2]
GEN1042 is being evaluated in a Phase 1/2 safety study with indications across malignant solid tumors, including non-small cell lung cancer,…
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CLINICAL_TRIALS trial_result · 2026-04-08Clinical Trial Update: Pembrolizumab + N-803 Alone or in Combination With PD-L1 t-haNK Cells for Resectable Head and Neck Squamous Cell Carcinoma [Phase 2]
A Phase 2 trial is recruiting to evaluate pembrolizumab with N-803, alone or with PD-L1 t-haNK cells, for resectable head and neck squamous …
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CLINICAL_TRIALS research · 2026-04-08Clinical Trial Update: Immunotherapy Combination: Irradiated PD-L1 CAR-NK Cells Plus Pembrolizumab Plus N-803 for Subjects With Recurrent/Metastatic Gastric or Head and Neck Cancer [Phase 2]
This clinical trial update describes a Phase 2 study evaluating irradiated PD-L1 CAR-NK cells in combination with pembrolizumab and N-803 fo…
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CLINICAL_TRIALS research · 2026-04-08Clinical Trial Update: Dose Determining Study of EXS74539 (REC-4539) in Participants With Select Solid Tumors [Phase 1]
This clinical trial update reports a Phase 1 dose-determining study of EXS74539 (REC-4539) in participants with select solid tumors, current…
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CLINICAL_TRIALS research · 2026-04-07Clinical Trial Update: A Study of VET3-TGI in Patients With Solid Tumors [Phase 1]
Phase 1 clinical trial update for VET3-TGI in patients with solid tumors, currently recruiting across multiple cancer types.
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CLINICAL_TRIALS research · 2026-04-07Clinical Trial Update: Clinical Trial Comparing Induction Treatment With EGFR-ADC MRG003 Alone or in Combination With the Anti PD1 Pucotenlimab, Followed by Radiochemotherapy in Locally Advanced Squamous Cell Cancers of the Head and Neck [Phase 2]
Phase 2 clinical trial evaluating induction treatment with EGFR-ADC MRG003 alone or in combination with the anti-PD1 pucotenlimab, followed …
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CLINICAL_TRIALS research · 2026-04-07Clinical Trial Update: High-dose Prophylactic Gabapentin (HOPE) vs. Placebo to Prevent Opioid Use for Oral Mucositis Pain During Concurrent Chemoradiation for Head and Neck Cancer [Phase 3]
Phase 3 trial assessing high-dose prophylactic gabapentin to prevent opioid use for oral mucositis pain during chemoradiation in head and ne…
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CLINICAL_TRIALS research · 2026-04-07Clinical Trial Update: A Study to Learn About the Study Medicine Called PF-08046876 in People With Advanced Solid Tumors [Phase 1]
Pfizer's Phase 1 study PF-08046876 is recruiting adults with various advanced solid tumors to evaluate safety and dosing. The trial includes…
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CLINICAL_TRIALS research · 2026-04-07Clinical Trial Update: Galenos 2 Immunonutrition in Head and Neck, Lung, and Rectal Cancer Patients [NA]
The clinical trial NCT07514754 investigating Galenos 2 immunonutrition for head and neck squamous cell carcinoma, locally advanced rectal ca…
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CLINICAL_TRIALS research · 2026-04-07Clinical Trial Update: FT836 With or Without Chemotherapy and/or Monoclonal Antibodies, in Participants With Advanced Solid Tumors [Phase 1]
FT836 is being studied in a Phase 1 trial for advanced solid tumors, administered with or without chemotherapy and/or monoclonal antibodies.…
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CLINICAL_TRIALS research · 2026-04-06Clinical Trial Update: NT219 Combined With Standard of Care Biologic Therapy in Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma [Phase 1, Phase 2]
Clinical trial update for NT219 in combination with standard of care biologic therapy in recurrent/metastatic Head and Neck Squamous Cell Ca…
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CLINICAL_TRIALS research · 2026-04-06Clinical Trial Update: A Longitudinal Multi-Omic Biomarker Profiling Study of Patients With Head & Neck Squamous Cell Carcinoma (HNSCC)
This clinical trial update describes a longitudinal multi-omic biomarker profiling study in patients with head and neck squamous cell carcin…
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CLINICAL_TRIALS research · 2026-04-06Clinical Trial Update: Neoadjuvant Cemiplimab for the Treatment of Resectable NSCLC, HCC, and HNSCC in Adult Patients [Phase 2]
Ongoing Phase 2 neoadjuvant trial evaluating cemiplimab for resectable non-small cell lung cancer, hepatocellular carcinoma, and head and ne…
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CLINICAL_TRIALS research · 2026-04-06Clinical Trial Update: GALENOS 1 in Head and Neck, Lung, and Rectal Cancer Patients
The GALENOS 1 trial is currently recruiting for patients with head and neck squamous cell carcinoma, locally advanced rectal cancer, and lun…
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CLINICAL_TRIALS trial_result · 2026-04-06Clinical Trial Update: Phase 3 Study of PDS0101 and Pembrolizumab in HPV16+ Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma [Phase 3]
A Phase 3 clinical trial evaluating PDS0101 in combination with pembrolizumab for HPV16-positive recurrent or metastatic head and neck squam…
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CLINICAL_TRIALS research · 2026-04-06Clinical Trial Update: Matching Primary Tumor and Blood Gene Expression Analysis of HPV-negative Squamous Head and Neck Cancers
This clinical trial is recruiting to compare gene expression profiles between primary head and neck tumors and blood in patients with HPV-ne…
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CLINICAL_TRIALS research · 2026-04-06Clinical Trial Update: Alpha Radiation Emitters Device (DaRT) in Combination With Check Point Inhibitor for the Treatment of Recurrent Unresectable or mHNSCC [NA]
This clinical trial update reports that recruitment is ongoing for a study of the Alpha Radiation Emitters Device (DaRT) in combination with…
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CLINICAL_TRIALS research · 2026-04-03Clinical Trial Update: Comparing Radiation Plus Cetuximab to Radiation Plus Chemotherapy in People With Head and Neck Cancer Who Cannot Receive Cisplatin [Phase 3]
Phase 3 clinical trial update on radiation plus cetuximab versus radiation plus non-cisplatin chemotherapy for head and neck cancer patients…