Head and Neck Squamous Cell Carcinoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2016-10-24Clinical Trial Update: Soy Isoflavones in Preventing Head and Neck Cancer Recurrence in Patients With Stage I-IV Head and Neck Cancer Undergoing Surgery [Phase 2]
Phase 2 clinical trial evaluating whether soy isoflavones can prevent recurrence of head and neck squamous cell carcinomas after surgery; re…
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CLINICAL_TRIALS withdrawal · 2016-09-30Clinical Trial Update: A Phase II Trial Evaluating WNT974 in Patients With Metastatic Head and Neck Squamous Cell Carcinoma [Phase 2]
A Phase II trial evaluating WNT974 for metastatic head and neck squamous cell carcinoma has been withdrawn.
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CLINICAL_TRIALS research · 2016-09-28Clinical Trial Update: The Clinical Study of the Poorly Differentiated Head and Neck Squamous Cell Carcinoma
A clinical study at Beijing Tongren Hospital is investigating treatment for poorly differentiated head and neck squamous cell carcinoma; no …
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CLINICAL_TRIALS trial_result · 2016-09-26Clinical Trial Update: A Study of Erlotinib (Tarceva) in Participants With Resected Head and Neck Squamous Cell Cancer [Phase 3]
Phase 3 trial of Erlotinib (Tarceva) in patients with resected head and neck squamous cell carcinoma was terminated; results have been poste…
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CLINICAL_TRIALS research · 2016-09-22Clinical Trial Update: A Phase 1 Dose Escalation Study of GC4419 in Combination With Chemoradiation for Squamous Cell Cancer of the Head & Neck [Phase 1]
A Phase 1 dose-escalation study of GC4419 in combination with chemoradiation for head and neck squamous cell carcinomas, including cancers o…
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CLINICAL_TRIALS research · 2016-09-14Clinical Trial Update: A Study of Pharmacodynamics of RO5083945 in Patients With Head and Neck Squamous Cell Carcinoma [Phase 1]
Phase 1 pharmacodynamics study of RO5083945 in patients with head and neck squamous cell carcinoma has completed.
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CLINICAL_TRIALS trial_result · 2016-09-08Clinical Trial Update: A Safety Study of MM-121 With Cetuximab and Irinotecan in Patients With Advanced Cancers [Phase 1]
Phase 1 safety study of MM-121 in combination with cetuximab and irinotecan in patients with advanced cancers, including colorectal cancer a…
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FDA approval · 2016-08-23FDA Approved: PACLITAXEL PACLITAXEL — Original Application (Heritage Pharmaceuticals Inc. d/b/a Avet Pharmaceuticals Inc.)
The FDA approved the original application for a generic paclitaxel product, manufactured by Heritage Pharmaceuticals Inc. d/b/a Avet Pharmac…
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CLINICAL_TRIALS trial_result · 2016-08-15Clinical Trial Update: Alisertib in Adults With Nonhematological Malignancies, Followed by Alisertib in Lung, Breast, Head and Neck or Gastroesophageal Malignancies [Phase 1, Phase 2]
Phase 1/Phase 2 trial results update for alisertib in adults with advanced nonhematological malignancies, including non-small cell lung canc…
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CLINICAL_TRIALS trial_result · 2016-08-11Clinical Trial Update: A Pharmacokinetic Study of Single Doses of Sativex in Treatment-induced Mucositis [Phase 1]
Phase 1 pharmacokinetic study evaluating single doses of Sativex (nabiximols) for treatment-induced mucositis in patients with head and neck…
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CLINICAL_TRIALS trial_result · 2016-08-10Clinical Trial Update: Bevacizumab, Cetuximab, and Cisplatin With IMRT (Intensity-Modulated Radiation Therapy) for Patients With Stage III/IV Head and Neck Squamous Cell Carcinoma [Phase 2]
Phase 2 clinical trial evaluating the combination of bevacizumab, cetuximab, and cisplatin with intensity-modulated radiation therapy for st…
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CLINICAL_TRIALS trial_result · 2016-08-10Clinical Trial Update: Weekly Nanoparticle Albumin-Bound Paclitaxel (Abraxane) + Weekly Cetuximab + Radiation Therapy (IMRT, Intensity-Modulated Radiation Therapy) in Patients With Stage III-IVB Head and Neck Squamous Cell Carcinoma (HNSCC) [Phase 1]
Phase 1 trial evaluating weekly nab-paclitaxel (Abraxane) plus weekly cetuximab with IMRT in stage III-IVB head and neck squamous cell carci…
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CLINICAL_TRIALS withdrawal · 2016-07-20Clinical Trial Update: Dose Escalation Trial of Neoadjuvant Sorafenib and Concurrent Sorafenib, Cisplatin and Radiation in Locally Advanced Squamous Cell Carcinomas of the Head and Neck (SCCHN) [Phase 1]
A Phase 1 dose-escalation trial of neoadjuvant sorafenib with cisplatin and radiation for locally advanced head and neck squamous cell carci…
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CLINICAL_TRIALS trial_result · 2016-07-12Clinical Trial Update: A Phase II Trial of Cetuximab and Bevacizumab in Patients With Recurrent or Metastatic Head and Neck Cancer [Phase 2]
A Phase II study evaluating cetuximab and bevacizumab in recurrent or metastatic head and neck squamous cell carcinoma has completed, with r…
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CLINICAL_TRIALS trial_result · 2016-07-11Clinical Trial Update: Active Immunization of Patients With Carcinoma of Oral Cavity or Oropharynx With Autologous Dendritic Cells Transfected With DNA From Autologous Tumor [Phase 1]
Phase 1 trial of an autologous dendritic cell vaccine transfected with a patient’s tumor DNA for oral cavity and oropharyngeal cancers was t…
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CLINICAL_TRIALS trial_result · 2016-06-13Clinical Trial Update: Dacomitinib Plus Radiotherapy, With and Without Cisplatin in Patients With Squamous Cell Carcinoma of the Head and Neck [Phase 1]
Phase 1 trial results update evaluating dacomitinib in combination with radiotherapy, with or without cisplatin, for head and neck squamous …
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CLINICAL_TRIALS trial_result · 2016-05-26Clinical Trial Update: TRACE: Tirapazamine-Radiation And Cisplatin Evaluation [Phase 3]
A Phase 3 trial (TRACE) evaluating tirapazamine with radiation and cisplatin for head and neck squamous cell carcinoma has completed.
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CLINICAL_TRIALS trial_result · 2016-05-10Clinical Trial Update: A Phase 1 Study in Participants With Advanced Cancer [Phase 1]
A Phase 1 trial sponsored by Eli Lilly in participants with advanced cancer, including anal squamous cell carcinoma, head and neck squamous …
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CLINICAL_TRIALS withdrawal · 2016-04-21Clinical Trial Update: Study of Efficacy and Safety of LJM716 and Cetuximab in Head and Neck Squamous Cell Carcinoma Patients [Phase 1, Phase 2]
A clinical trial assessing the combination of LJM716 and cetuximab for head and neck squamous cell carcinoma has been withdrawn.
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CLINICAL_TRIALS trial_result · 2016-04-20Clinical Trial Update: A Study of CP-751,871 in Patients With Recurrent Squamous Head and Neck Carcinoma [Phase 2]
Phase 2 study of CP-751,871 in recurrent squamous cell carcinoma of the head and neck has been terminated.
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CLINICAL_TRIALS trial_result · 2016-04-04Clinical Trial Update: Afatinib After Chemoradiation and Surgery in Treating Patients With Stage III-IV Squamous Cell Carcinoma of the Head and Neck at High-Risk of Recurrence [Phase 2]
Phase 2 trial evaluating afatinib after chemoradiation and surgery in high-risk stage III-IV head and neck squamous cell carcinoma (HNSCC); …
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CLINICAL_TRIALS trial_result · 2016-03-31Clinical Trial Update: A Prospective Study of Prophylactic Gastrostomy in Head and Neck Cancer Patients Undergoing Chemoradiotherapy [NA]
A prospective trial evaluating prophylactic gastrostomy in head and neck cancer patients undergoing chemoradiotherapy was terminated.
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CLINICAL_TRIALS trial_result · 2016-03-25Clinical Trial Update: Magnetic Resonance Imaging (MRI) in the Assessment of Head and Neck Squamous Cell Carcinoma (HNSCC) Response
This clinical trial update reports termination of a study evaluating the use of MRI to assess treatment response in head and neck squamous c…
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CLINICAL_TRIALS trial_result · 2016-03-09Clinical Trial Update: Mometasone Furoate Cream Reduces Acute Radiation Dermatitis in Head and Neck Squamous Cell Carcinomas' Patients [Phase 4]
Phase 4 trial suggests that topical mometasone furoate cream reduces acute radiation dermatitis in patients with head and neck squamous cell…
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CLINICAL_TRIALS research · 2016-03-02Clinical Trial Update: Assessing Tumor Response and IMRT Treat Plan After IC Based on FDG-PET/CT for Locally Advanced HNSCC [Phase 2]
This entry reports the completion of a Phase 2 trial evaluating tumor response and IMRT planning after induction chemotherapy guided by FDG-…