Head and Neck Squamous Cell Carcinoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2016-02-23Clinical Trial Update: Valproic Acid and Platinum-based Chemoradiation in Locally Advanced Head and Neck Squamous Cell Carcinoma [Phase 2]
This Phase 2 study evaluated valproic acid in combination with platinum-based chemoradiation for locally advanced head and neck squamous cel…
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CLINICAL_TRIALS trial_result · 2016-02-10Clinical Trial Update: Everolimus, Carboplatin, and Paclitaxel in Locally Advanced Head and Neck Cancer That Cannot Be Removed by Surgery [Phase 1, Phase 2]
This clinical trial update reports on a Phase 1/2 study of everolimus in combination with carboplatin and paclitaxel for locally advanced he…
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CLINICAL_TRIALS trial_result · 2016-02-04Clinical Trial Update: Trial of RAD001 and Erlotinib With Recurrent Head and Neck Squamous Cell Carcinoma [Phase 2]
Phase 2 trial evaluating the combination of everolimus (RAD001) and erlotinib for recurrent head and neck squamous cell carcinoma has comple…
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CLINICAL_TRIALS research · 2016-01-22Clinical Trial Update: State of the Art Photon Therapy Versus Particle Therapy for Recurrent Head & Neck Tumors; a Planning Study
A completed planning study comparing state-of-the-art photon therapy versus particle therapy for recurrent head and neck tumors is reported.…
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CLINICAL_TRIALS trial_result · 2015-12-28Clinical Trial Update: Safety Study of Modified Vaccinia Virus to Cancer [Phase 1]
Phase 1 safety study of Modified Vaccinia Virus in cancer patients has completed, evaluating safety across multiple cancer types including m…
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CLINICAL_TRIALS trial_result · 2015-12-23Clinical Trial Update: Study of Proxinium Plus Best Supportive Care Versus Best Supportive Care for Patients With Advanced Head and Neck Cancer [Phase 2, Phase 3]
Phase 2/3 trial evaluating Proxinium plus best supportive care versus best supportive care for advanced head and neck cancer has been termin…
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CLINICAL_TRIALS trial_result · 2015-12-23Clinical Trial Update: Molecular Effects of Short-Term Celecoxib Treatment on Head and Neck Squamous Cell Carcinoma [NA]
A completed clinical trial evaluated the molecular effects of short-term Celecoxib treatment in head and neck squamous cell carcinoma.
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CLINICAL_TRIALS trial_result · 2015-12-17Clinical Trial Update: Study of Safety and Efficacy of Talimogene Laherparepvec With Cisplatin and Radiotherapy for Treatment of Locally Advanced Head and Neck Cancer [Phase 3]
A Phase 3 trial evaluating talimogene laherparepvec with cisplatin and radiotherapy for locally advanced head and neck cancer was terminated…
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CLINICAL_TRIALS trial_result · 2015-12-10Clinical Trial Update: Prognostic Value of CTC in HNSCC Patients
This clinical trial update evaluates the prognostic value of circulating tumor cells in patients with Head and neck squamous cell carcinoma,…
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CLINICAL_TRIALS trial_result · 2015-12-09Clinical Trial Update: Phase II Trial Evaluating Axitinib In Patients With Unresectable, Recurrent Or Metastatic Head And Neck Cancer [Phase 2]
A Phase II study evaluating axitinib in patients with unresectable, recurrent, or metastatic head and neck squamous cell carcinoma has been …
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CLINICAL_TRIALS trial_result · 2015-11-20Clinical Trial Update: Study of Pralatrexate With Vitamin B12 and Folic Acid Supplementation for Previously Treated Recurrent or Metastatic Head and Neck Squamous Cell Cancer (HNSCC) [Phase 2]
Phase 2 trial evaluating pralatrexate with vitamin B12 and folic acid for previously treated recurrent or metastatic head and neck squamous …
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CLINICAL_TRIALS trial_result · 2015-09-01Clinical Trial Update: Phase II Randomized Trial of the Combination of Cetuximab and Sorafenib or Single Agent Cetuximab [Phase 2]
This Phase II randomized trial assessed cetuximab with sorafenib versus cetuximab alone in metastatic head and neck squamous cell carcinomas…
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CLINICAL_TRIALS trial_result · 2015-08-10Clinical Trial Update: Determine Tumor Response Using Fluorodeoxyglucose (FDG)- Positron Emission Tomography (PET)/Computed Tomography (CT) Before and After Cetuximab in Patients With Head and Neck Cancer [Phase 2]
Phase 2 study assessing tumor response to cetuximab in head and neck squamous cell carcinoma using FDG-PET/CT before and after treatment; re…
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CLINICAL_TRIALS trial_result · 2015-07-10Clinical Trial Update: A Study of PF-00299804 When Given Through a Feeding Tube in Locally Advanced Head and Neck Squamous Cell Carcinoma [NA]
This update reports the completion of a clinical trial evaluating PF-00299804 when administered via feeding tube in locally advanced head an…
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CLINICAL_TRIALS research · 2015-06-30Clinical Trial Update: Cisplatin Plus Raltitrexed or 5-fluorouracil Concurrent With Radiotherapy for Head and Neck Squamous Cell Cancer [Phase 3]
Phase 3 trial evaluating cisplatin plus raltitrexed or cisplatin plus 5-fluorouracil with radiotherapy for head and neck squamous cell carci…
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CLINICAL_TRIALS trial_result · 2015-06-18Clinical Trial Update: Pilot Study of Raltegravir and Cisplatin in Squamous Cell Carcinoma of Head and Neck [EARLY_Phase 1]
This report documents the completion of a Phase 1 pilot trial evaluating the combination of raltegravir and cisplatin in head and neck squam…
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CLINICAL_TRIALS trial_result · 2015-05-20Clinical Trial Update: Benefits of Exercise Training in Head and Neck Cancer Patients Undergoing Organ-Preserving Definitive Therapy [NA]
This ClinicalTrials.gov update notes the completed study evaluating the benefits of exercise training in patients with head and neck squamou…
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CLINICAL_TRIALS trial_result · 2015-05-05Clinical Trial Update: Cediranib Maleate in Treating Patients With Recurrent or Newly Diagnosed Metastatic Head and Neck Cancer [Phase 2]
A Phase 2 trial update for cediranib maleate in patients with recurrent or metastatic head and neck squamous cell carcinoma has completed en…
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CLINICAL_TRIALS research · 2015-04-22Clinical Trial Update: The Princess Alexandra Hospital and the QIMR Berghofer Medical Research Institute Head and Neck Cancer Study
This entry updates a head and neck cancer study led by The Princess Alexandra Hospital and the QIMR Berghofer Medical Research Institute, fo…
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CLINICAL_TRIALS trial_result · 2015-04-15Clinical Trial Update: Lapatinib Ditosylate in Treating Patients With Metastatic or Recurrent Head and Neck Cancer [Phase 2]
A Phase 2 trial evaluating lapatinib ditosylate in patients with metastatic or recurrent head and neck cancer has been completed.
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CLINICAL_TRIALS trial_result · 2015-04-14Clinical Trial Update: LUX-Head&Neck 1: A Phase III Trial of Afatinib (BIBW2992) Versus Methotrexate for the Treatment of Recurrent and/or Metastatic (R/M) Head and Neck Squamous Cell Cancer After Platinum Based Chemotherapy [Phase 3]
Phase 3 trial comparing afatinib to methotrexate for recurrent/metastatic head and neck squamous cell carcinoma after platinum therapy; stud…
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FDA approval · 2015-04-10FDA Approved: ERBITUX — Supplemental Application (ImClone LLC)
The FDA approved a supplemental application for ERBITUX (cetuximab) submitted by ImClone LLC. This action pertains to a supplemental approva…
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CLINICAL_TRIALS trial_result · 2015-03-30Clinical Trial Update: Study of Unilateral Neck Irradiation in Patients With SCC of the Head and Neck [NA]
This update notes the completion of a trial evaluating unilateral neck irradiation in patients with head and neck squamous cell carcinoma.
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CLINICAL_TRIALS trial_result · 2015-03-27Clinical Trial Update: Study of Biological Effect of Tarceva (OSI-774) for Patients Stricken by ENT Epidermoid Carcinoma [NA]
A completed clinical trial evaluating the biological effect of Tarceva (erlotinib) in patients with head and neck squamous cell carcinoma.
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CLINICAL_TRIALS trial_result · 2015-03-26Clinical Trial Update: Pharmacogenetic Response to Chemotherapy Induction for ORL Cancers
A completed clinical trial evaluated pharmacogenetic responses to induction chemotherapy across head and neck squamous cell carcinomas of th…