Head and Neck Squamous Cell Carcinoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2017-05-18Clinical Trial Update: Fosaprepitant Dimeglumine, Palonosetron Hydrochloride, and Dexamethasone in Preventing Nausea and Vomiting Caused by Cisplatin in Patients With Stage III or Stage IV Head and Neck Cancer Undergoing Chemotherapy and Radiation Therapy [Phase 2]
Phase 2 trial evaluating a three-drug antiemetic regimen (fosaprepitant dimeglumine, palonosetron hydrochloride, and dexamethasone) for prev…
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CLINICAL_TRIALS research · 2017-05-17Clinical Trial Update: Biomakers in Tissue Samples From Patients With Recurrent and/or Metastatic Squamous Cell Cancer of the Head and Neck Previously Treated With Cisplatin With or Without Cetuximab
This completed clinical trial studied biomarkers in tissue samples from patients with recurrent or metastatic head and neck squamous cell ca…
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CLINICAL_TRIALS research · 2017-05-17Clinical Trial Update: Biomarkers of Response in Blood and Tumor Tissue Samples From Patients With Unresectable Stage IV Squamous Cell Cancer of the Head and Neck Previously Treated With Cetuximab, Cisplatin, and Radiation Therapy
A completed clinical trial update describing biomarkers of response in blood and tumor tissue from patients with unresectable stage IV squam…
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CLINICAL_TRIALS trial_result · 2017-05-11Clinical Trial Update: Cetuximab + Taxotere With Low Dose Fractionated Radiation for Head and Neck Carcinoma [Phase 2]
A Phase 2 trial evaluating cetuximab plus docetaxel with low-dose fractionated radiation for head and neck squamous cell carcinoma was termi…
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CLINICAL_TRIALS research · 2017-05-08Clinical Trial Update: An Observational Study to Evaluate the Safety and Efficacy of Cetuximab in Combination With Platinum-based Chemotherapy in the First-line Treatment of Recurrent or Metastatic Squamous Cell Carcinoma of Head and Neck
An observational study assessing the safety and efficacy of cetuximab in combination with platinum-based chemotherapy as first-line treatmen…
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CLINICAL_TRIALS other · 2017-05-04Clinical Trial Update: Monitoring of Oral Human Papillomavirus Infection (HPV) in HPV-positive Oropharyngeal Squamous Cell Carcinoma (OPSCC) [NA]
Terminated clinical trial update from UNC Lineberger Comprehensive Cancer Center on monitoring oral HPV infection in HPV-positive oropharyng…
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CLINICAL_TRIALS research · 2017-05-01Clinical Trial Update: Study to Evaluate the Efficacy and Safety of Docetaxel Polymeric Micelle (PM) in Recurrent or Metastatic HNSCC [Phase 2]
A Phase 2 clinical trial is evaluating the efficacy and safety of a polymeric micelle formulation of docetaxel in recurrent or metastatic he…
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CLINICAL_TRIALS withdrawal · 2017-04-24Clinical Trial Update: Talazoparib in Treating Patients With Advanced or Metastatic Solid Tumors That Cannot Be Removed by Surgery and Liver or Kidney Dysfunction [Phase 1]
A Phase 1 clinical trial of talazoparib in patients with advanced or metastatic solid tumors unsuitable for surgery and with liver or kidney…
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CLINICAL_TRIALS research · 2017-04-17Clinical Trial Update: Docetaxel and Loplatin Induction Chemotherapy Followed by Concurrent Chemoradiotherapy for Locally Advanced SCCHN [Phase 2]
A Phase 2 trial evaluates induction chemotherapy with docetaxel and cisplatin (Loplatin) followed by concurrent chemoradiotherapy for locall…
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CLINICAL_TRIALS trial_result · 2017-04-14Clinical Trial Update: Capecitabine and Vorinostat in Treating Patients With Recurrent and/or Metastatic Head and Neck Cancer [Phase 2]
A Phase 2 trial evaluating the combination of capecitabine and vorinostat for recurrent/metastatic head and neck squamous cell carcinomas wa…
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CLINICAL_TRIALS trial_result · 2017-04-07Clinical Trial Update: Chemotherapy With Cetuximab in Treating Patients With Recurrent or Metastatic Head and Neck Cancer [Phase 2]
Phase 2 study evaluating chemotherapy with cetuximab in patients with recurrent or metastatic head and neck squamous cell carcinoma; results…
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CLINICAL_TRIALS trial_result · 2017-04-04Clinical Trial Update: Radiation, Cetuximab and Pemetrexed With or Without Bevacizumab in Locally Advanced Head and Neck Cancer [Phase 2]
Phase 2 trial results are reported for a chemoradiation regimen including cetuximab and pemetrexed with or without bevacizumab in locally ad…
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CLINICAL_TRIALS trial_result · 2017-03-06Clinical Trial Update: Lapatinib and Radiation for Stage III-IV Head and Neck Cancer Patients Who Cannot Tolerate Concurrent Chemotherapy [Phase 2]
Phase 2 trial of lapatinib with radiation for stage III-IV head and neck squamous cell carcinoma in patients unable to tolerate concurrent c…
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CLINICAL_TRIALS trial_result · 2017-03-06Clinical Trial Update: SB-715992 in Treating Patients With Recurrent or Metastatic Head and Neck Cancer [Phase 2]
Phase 2 clinical trial update for SB-715992 in patients with recurrent or metastatic head and neck cancer; the study completed and results w…
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CLINICAL_TRIALS trial_result · 2017-03-03Clinical Trial Update: Quantitative Optical Sensor Findings in Head & Neck Squamous Cell Carcinoma
Clinical trial update reporting quantitative optical sensor findings in head and neck squamous cell carcinoma.
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CLINICAL_TRIALS trial_result · 2017-02-15Clinical Trial Update: Safety and Efficacy of Radiation/Cetuximab Plus EGFR Antisense DNA for Head and Neck Squamous Cell Carcinoma [Phase 1]
Phase 1 trial evaluating radiation plus cetuximab and an EGFR antisense DNA agent for head and neck squamous cell carcinoma; the study was t…
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CLINICAL_TRIALS trial_result · 2017-02-08Clinical Trial Update: Pilot Study of Metformin in HNSCC to Investigate the Effects of MF, Tumor Genotype and MF-genotype Interactions, on Tumor Metabolism and Anoikis [EARLY_Phase 1]
A pilot early-phase study of metformin in head and neck squamous cell carcinoma has been terminated. The study investigated metformin effect…
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CLINICAL_TRIALS withdrawal · 2017-02-08Clinical Trial Update: Postoperative Concurrent Chemoradiation for Head and Neck Cancer With Multiple Minor Risk [NA]
A clinical trial evaluating postoperative concurrent chemoradiation for head and neck squamous cell carcinoma has been terminated.
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CLINICAL_TRIALS trial_result · 2017-02-06Clinical Trial Update: Temsirolimus With or Without Cetuximab in Patients With Recurrent and/or Metastatic Head and Neck Cancer Who Did Not Respond to Previous Therapy [Phase 2]
Phase 2 trial evaluating temsirolimus with or without cetuximab in patients with recurrent and/or metastatic head and neck squamous cell car…
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CLINICAL_TRIALS trial_result · 2017-01-19Clinical Trial Update: Chemotherapy Plus Radiation Therapy in Treating Patients With Squamous Cell Cancer of the Head and Neck [Phase 1]
A Phase 1 study evaluating chemotherapy plus radiation therapy for patients with head and neck squamous cell carcinoma has been completed.
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CLINICAL_TRIALS trial_result · 2017-01-13Clinical Trial Update: Study of Prophylactic Topical Dapsone 5% Gel Versus Moisturizer for Cetuximab-induced Papulopustular (Acneiform) Rash in Patients With mCRC or HNSCC Without Previous or Concurrent RT [Phase 3]
A Phase 3 trial comparing prophylactic topical dapsone 5% gel with moisturizer to prevent cetuximab-induced acneiform rash in patients with …
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CLINICAL_TRIALS trial_result · 2017-01-04Clinical Trial Update: Randomized Amifostine For SCCHN [Phase 2]
Phase 2 randomized trial of amifostine (Ethyol) to mitigate chemotherapy- and radiotherapy-related toxicities (mucositis, xerostomia) in hea…
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CLINICAL_TRIALS trial_result · 2016-11-29Clinical Trial Update: DAHANCA 25B: Progressive Resistance Training as Intervention for Regaining Muscle Mass After Radiation Therapy in Patients With HNSCC [NA]
This completed trial evaluated progressive resistance training as an intervention to regain muscle mass after radiation therapy in patients …
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CLINICAL_TRIALS trial_result · 2016-11-25Clinical Trial Update: DAHANCA 19: The Importance of the EGFr-inhibitor Zalutumumab for the Outcome After Curative Radiotherapy for HNSCC [Phase 3]
Phase 3 trial DAHANCA 19 evaluates the EGFR inhibitor zalutumumab for outcomes after curative radiotherapy in head and neck cancer. The docu…
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CLINICAL_TRIALS trial_result · 2016-11-25Clinical Trial Update: IAEA-HypoX. Accelerated Radiotherapy With or Without Nimorazole in Squamous Cell Carcinoma of the Head and Neck [Phase 3]
A Phase 3 trial evaluating accelerated radiotherapy with or without nimorazole for head and neck squamous cell carcinoma was terminated.