Head and Neck Squamous Cell Carcinoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2018-12-19Clinical Trial Update: Cetuximab With or Without Tivantinib in Treating Patients With Head and Neck Cancer That Is Recurrent, Metastatic, or Cannot Be Removed by Surgery [Phase 2]
Phase 2 trial evaluating cetuximab with or without tivantinib in recurrent/metastatic head and neck squamous cell carcinoma; study completed…
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CLINICAL_TRIALS trial_result · 2018-11-16Clinical Trial Update: SCT200 Injection in Patients With Head and Neck Squamous Cell Carcinoma [Phase 2]
Phase 2 clinical trial update for SCT200 injections in patients with head and neck squamous cell carcinoma.
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CLINICAL_TRIALS trial_result · 2018-11-16Clinical Trial Update: Stereotactic Body Radiation Therapy in Treating Patients With High Risk Locally Advanced Head and Neck Cancer [NA]
A terminated clinical trial evaluating stereotactic body radiation therapy for high-risk locally advanced head and neck cancers; results wer…
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CLINICAL_TRIALS trial_result · 2018-10-09Clinical Trial Update: A Study of Apatinib Plus Tegafur Gimeracil Oteracil in Recurrent/Metastatic Head and Neck Cancers [Phase 2]
Phase 2 clinical trial evaluating apatinib plus tegafur gimeracil oteracil in recurrent/metastatic head and neck squamous cell carcinoma.
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CLINICAL_TRIALS trial_result · 2018-09-13Clinical Trial Update: Role of SAMITAL® in the Relief of Chemo-radiation (CT-RT) Induced Oral Mucositis in Head and Neck Cancer Patients [Phase 2]
Phase 2 clinical trial update evaluating SAMITAL® for relief of chemo-radiation–induced oral mucositis in head and neck cancer patients has …
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CLINICAL_TRIALS trial_result · 2018-08-21Clinical Trial Update: Reactivating NK Cells in Treating Refractory Head and Neck Cancer [Phase 1, Phase 2]
A phase 1/2 trial investigating reactivation of natural killer (NK) cells for refractory head and neck cancers, including nasopharyngeal can…
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CLINICAL_TRIALS trial_result · 2018-08-16Clinical Trial Update: ERBITUX® Followed by Adjuvant Treatment With Chemoradiation and ERBITUX® for Locally Advanced Head and Neck Squamous Cell Carcinoma [Phase 2]
Phase 2 trial evaluating ERBITUX followed by adjuvant chemoradiation with ERBITUX for locally advanced head and neck squamous cell carcinoma…
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CLINICAL_TRIALS trial_result · 2018-08-13Clinical Trial Update: Pembrolizumab (MK-3475) Versus Standard Treatment for Recurrent or Metastatic Head and Neck Cancer (MK-3475-040/KEYNOTE-040) [Phase 3]
Phase 3 trial comparing pembrolizumab to standard treatment for recurrent or metastatic head and neck cancer has completed with results post…
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CLINICAL_TRIALS trial_result · 2018-07-26Clinical Trial Update: A Phase I/II Study Afatinib/Carboplatin/Paclitaxel Induction Chemotherapy In HPV-Negative HNSCC. [Phase 1, Phase 2]
A Phase I/II trial evaluating induction chemotherapy with afatinib, carboplatin, and paclitaxel for HPV-negative head and neck squamous cell…
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CLINICAL_TRIALS trial_result · 2018-07-23Clinical Trial Update: Prognostic Value of 18FDG PET/CT Textural Indices in HNSCC
The trial evaluating prognostic value of 18F-FDG PET/CT textural indices in head and neck squamous cell carcinoma has completed. The provide…
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CLINICAL_TRIALS research · 2018-07-18Clinical Trial Update: An Open Label, Single Arm, Multicenter Phase II Study of BYL719 in Patients With Recurrent or Metastatic Squamous Cell Carcinoma of Head and Neck Who Failed to Respond to Platinum-based Therapy. [Phase 2]
Open-label, single-arm Phase II trial evaluating BYL719 (alpelisib) in recurrent or metastatic head and neck squamous cell carcinoma after p…
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CLINICAL_TRIALS trial_result · 2018-07-18Clinical Trial Update: AMG 319 in HPV Positive and Negative HNSCC [Phase 2]
Phase 2 trial of AMG 319 in HPV-positive and HPV-negative head and neck squamous cell carcinoma has been terminated.
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CLINICAL_TRIALS research · 2018-07-18Clinical Trial Update: Evaluation of the Overall Quality of Life After the Neck Dissection Retro-spinal Sector (IIb), in Squamous Cell Carcinomas Clinical and Radiological N0 VADS
This clinical trial update reports an ongoing study evaluating quality of life after neck dissection in head and neck squamous cell carcinom…
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CLINICAL_TRIALS trial_result · 2018-06-26Clinical Trial Update: Study of Efficacy and Safety of Buparlisib (BKM120) Plus Paclitaxel Versus Placebo Plus Paclitaxel in Recurrent or Metastatic Head and Neck Cancer Previously Pre-treated With a Platinum Therapy [Phase 2]
A phase 2 study comparing buparlisib plus paclitaxel versus placebo plus paclitaxel in recurrent or metastatic head and neck squamous cell c…
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CLINICAL_TRIALS trial_result · 2018-05-24Clinical Trial Update: Sorafenib Tosylate, Cisplatin, and Docetaxel in Treating Patients With Recurrent or Metastatic Squamous Cell Carcinoma of the Head and Neck [Phase 1]
Phase 1 trial evaluating the safety and preliminary activity of sorafenib tosylate in combination with cisplatin and docetaxel for patients …
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CLINICAL_TRIALS trial_result · 2018-05-21Clinical Trial Update: A Phase Ib/II Study of BYL719 and Cetuximab in Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma [Phase 1, Phase 2]
Phase Ib/II study of BYL719 (alpelisib) with cetuximab in recurrent or metastatic head and neck squamous cell carcinoma was terminated; resu…
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CLINICAL_TRIALS trial_result · 2018-05-16Clinical Trial Update: Phase 1 and 2 Study of PX-866 and Cetuximab [Phase 1, Phase 2]
This document reports a completed Phase 1/2 clinical trial evaluating PX-866 in combination with cetuximab. The study enrolled patients with…
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CLINICAL_TRIALS trial_result · 2018-04-17Clinical Trial Update: Study of IMC-A12, Alone or in Combination With Cetuximab, in Participants With Recurrent or Metastatic Squamous Cell Carcinoma (MSCC) of the Head and Neck [Phase 2]
Phase 2 study evaluating IMC-A12 (cixutumumab) alone or with cetuximab in recurrent or metastatic squamous cell carcinoma of the head and ne…
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CLINICAL_TRIALS trial_result · 2018-03-30Clinical Trial Update: A Study Evaluating Safety and Pharmacokinetics of ABBV-221 in Subjects With Advanced Solid Tumor Types Likely to Exhibit Elevated Levels of Epidermal Growth Factor Receptor [Phase 1]
A Phase 1 trial evaluating the safety and pharmacokinetics of ABBV-221 in adults with advanced solid tumors likely to overexpress EGFR was t…
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CLINICAL_TRIALS research · 2018-03-29Clinical Trial Update: Prospective Trial of Serial CT Imaging for Evaluation of Dosimetric/Volumetric Changes During IMRT for Head/Neck Cancer
This clinical trial update from the University of Miami describes a prospective study using serial CT imaging to evaluate dosimetric and vol…
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FDA approval · 2018-03-15FDA Approved: METHOTREXATE — Supplemental Application (Hospira, Inc.)
FDA approved a supplemental application for Methotrexate submitted by Hospira, Inc.
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CLINICAL_TRIALS trial_result · 2018-02-26Clinical Trial Update: Carboplatin, Paclitaxel, Cetuximab, and Erlotinib Hydrochloride in Treating Patients With Metastatic or Recurrent Head and Neck Squamous Cell Cancer [Phase 2]
This Phase 2 trial evaluated the combination of carboplatin, paclitaxel, cetuximab, and erlotinib for metastatic or recurrent head and neck …
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CLINICAL_TRIALS trial_result · 2018-02-06Clinical Trial Update: A Retrospective Clinical Study of Apatinib in Combination With Radiotherapy / Chemotherapy Second-line and Above in the Treatment of Recurrent / Metastatic Head and Neck Squamous Cell Carcinoma [Phase 2]
Phase 2 retrospective clinical study evaluating apatinib combined with radiotherapy/chemotherapy as second-line or higher treatment for recu…
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CLINICAL_TRIALS trial_result · 2018-01-03Clinical Trial Update: Trial of pIL-12 Electroporation in Squamous Cell Carcinoma of the Head and Neck (IL12HNSCC) [Phase 2]
Phase 2 trial of pIL-12 electroporation in head and neck squamous cell carcinoma was terminated; results posted in 2018.
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CLINICAL_TRIALS research · 2017-11-29Clinical Trial Update: A Biomarker-driven, Open Label, Single Arm, Multicentre Phase II Study of Abemaciclib in Patients With Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma Who Failed to Platinum-based Therapy [Phase 2]
Phase II biomarker-driven, open-label, single-arm, multicenter study evaluating abemaciclib in patients with recurrent or metastatic head an…