Head and Neck Squamous Cell Carcinoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2020-02-07Clinical Trial Update: Preoperative Administration of Olaparib With Cisplatin or With Durvalumab or Alone or no Tratment in Patients Who Are Candidates for Surgery of Carcinoma of the Head and Neck. [Phase 2]
Phase 2 clinical trial evaluating preoperative olaparib with cisplatin, with durvalumab, or alone (or no treatment) in patients planned for …
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CLINICAL_TRIALS trial_result · 2020-02-05Clinical Trial Update: SCT-I10A Plus Standard Chemotherapy in First-line Recurrent/ Metastatic Head and Neck Squamous Cell Carcinoma [Phase 3]
Phase 3 clinical trial update for SCT-I10A plus standard chemotherapy in first-line recurrent/metastatic head and neck squamous cell carcino…
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CLINICAL_TRIALS trial_result · 2020-01-27Clinical Trial Update: Epacadostat and Pembrolizumab in Patients With Head and Neck Cancer That Have Failed Prior Immunotherapy [Phase 2]
Phase 2 trial evaluating epacadostat with pembrolizumab in head and neck cancer that progressed after prior immunotherapy; study terminated …
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CLINICAL_TRIALS trial_result · 2019-12-12Clinical Trial Update: Safety and Efficacy of SCT-I10A in Head and Neck Squamous Cell Carcinoma [Phase 2]
Phase 2 clinical trial update examining safety and efficacy of SCT-I10A in head and neck squamous cell carcinoma.
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CLINICAL_TRIALS trial_result · 2019-11-20Clinical Trial Update: Metformin Hydrochloride in Affecting Cytokines and Exosomes in Patients With Head and Neck Cancer [EARLY_Phase 1]
A completed early-phase trial tested metformin hydrochloride for effects on cytokines and exosomes in patients with head and neck cancers, i…
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CLINICAL_TRIALS trial_result · 2019-11-15Clinical Trial Update: Chemotherapy With or Without Bevacizumab in Treating Patients With Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma [Phase 3]
Phase 3 study evaluating chemotherapy with or without bevacizumab for recurrent or metastatic head and neck squamous cell carcinoma; results…
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CLINICAL_TRIALS trial_result · 2019-11-15Clinical Trial Update: Chemotherapy With or Without Bevacizumab in Treating Patients With Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma [Phase 3]
Phase 3 trial evaluating chemotherapy with or without bevacizumab in recurrent or metastatic head and neck squamous cell carcinoma.
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CLINICAL_TRIALS trial_result · 2019-11-15Clinical Trial Update: Neoadjuvant Anti-PD-1 Antibody (Toripalimab) or Combined With Chemotherapy in HNSCC Patients [Phase 2]
Phase 2 trial update evaluating neoadjuvant anti-PD-1 antibody toripalimab alone or with chemotherapy in head and neck squamous cell carcino…
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CLINICAL_TRIALS trial_result · 2019-10-03Clinical Trial Update: Study of MEDI4736 Monotherapy and in Combination With Tremelimumab Versus Standard of Care Therapy in Patients With Head and Neck Cancer [Phase 3]
Phase 3 trial evaluating MEDI4736 (durvalumab) alone and in combination with tremelimumab versus standard of care in recurrent/metastatic PD…
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CLINICAL_TRIALS trial_result · 2019-09-12Clinical Trial Update: Study of the Combination of Acalabrutinib (ACP-196) and Pembrolizumab in Advanced Head and Neck Squamous Cell Carcinoma [Phase 2]
Phase 2 trial evaluating acalabrutinib plus pembrolizumab in advanced head and neck squamous cell carcinoma has completed with results poste…
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CLINICAL_TRIALS trial_result · 2019-09-11Clinical Trial Update: Potentiation of Cetuximab by Tregs Depletion With CSA in Advanced Head & Neck Cancer [Phase 2]
A Phase 2 trial investigated whether depleting regulatory T cells with CSA could enhance cetuximab efficacy in advanced head and neck cancer…
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CLINICAL_TRIALS trial_result · 2019-09-10Clinical Trial Update: Pembrolizumab Plus Epacadostat, Pembrolizumab Monotherapy, and the EXTREME Regimen in Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma (KEYNOTE-669/ECHO-304) [Phase 3]
Phase 3 trial KEYNOTE-669/ECHO-304 evaluated pembrolizumab with or without epacadostat and the EXTREME regimen in recurrent or metastatic he…
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CLINICAL_TRIALS trial_result · 2019-07-18Clinical Trial Update: Sintilimab in Combination With Nab-paclitaxel in Patients With HNSCC (Head and Neck Squamous Cell Carcinoma ) [Phase 2]
Phase 2 trial update evaluating Sintilimab in combination with Nab-paclitaxel for head and neck squamous cell carcinoma is in early stages w…
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CLINICAL_TRIALS trial_result · 2019-06-28Clinical Trial Update: An Experimental Study to Compare Treatment Response and Toxicities of Concurrent Chemoradiation With Weekly Cisplatin and Three Weekly Cisplatin in Locally Advanced Head and Neck Cancer. [Phase 4]
A Phase 4 trial comparing concurrent chemoradiation with weekly cisplatin versus three-weekly cisplatin in locally advanced head and neck ca…
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CLINICAL_TRIALS trial_result · 2019-06-26Clinical Trial Update: Temsirolimus + Weekly Paclitaxel + Carboplatin for Recurrent or Metastatic Head and Neck Squamous Cell Cancer (HNSCC) [Phase 1, Phase 2]
Phase 1/2 trial evaluating temsirolimus with weekly paclitaxel and carboplatin for recurrent/metastatic head and neck squamous cell carcinom…
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CLINICAL_TRIALS trial_result · 2019-06-11Clinical Trial Update: A Trial of Tadalafil in Patients With Squamous Cell Carcinoma of the Upper Aero Digestive Tract [Phase 2]
Phase 2 trial of tadalafil in patients with head and neck squamous cell carcinoma has completed with results posted in 2019.
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CLINICAL_TRIALS trial_result · 2019-06-05Clinical Trial Update: Combination Chemotherapy With or Without Veliparib in Treating Patients With Stage IV Head and Neck Cancer [Phase 1, Phase 2]
Phase 1/2 trial evaluating combination chemotherapy with or without veliparib in stage IV head and neck cancer; study completed with results…
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CLINICAL_TRIALS trial_result · 2019-04-16Clinical Trial Update: Phase III Trial to Assess Efficacy and Safety of Cetuximab for the Treatment of Chinese Participants With Head and Neck Cancer [Phase 3]
Phase III trial evaluating cetuximab for efficacy and safety in Chinese participants with head and neck squamous cell carcinoma has complete…
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CLINICAL_TRIALS trial_result · 2019-04-10Clinical Trial Update: BGJ398 in Treating Patients With FGFR Positive Recurrent Head and Neck Cancer [Phase 2]
Phase 2 trial of BGJ398 (infigratinib) for FGFR-positive recurrent head and neck cancer was terminated; results posted in 2019.
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CLINICAL_TRIALS trial_result · 2019-03-18Clinical Trial Update: Phase II Trial of HM781-36B in Patients With Metastatic/Recurrent Head and Neck Squamous Cell Carcinoma (HNSCC) After Failure of or Unfit for Platinum-containing Therapy [Phase 2]
Phase II trial update for HM781-36B in metastatic/recurrent head and neck squamous cell carcinoma after platinum therapy failure or ineligib…
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CLINICAL_TRIALS trial_result · 2019-03-01Clinical Trial Update: LUX-Head & Neck 4: Afatinib (BIBW 2992) Versus Placebo for the Treatment of Head and Neck Squamous Cell Cancer After Treatment With Chemo-radiotherapy [Phase 3]
Phase 3 trial comparing afatinib to placebo for head and neck squamous cell cancer after chemo-radiotherapy was terminated with posted resul…
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CLINICAL_TRIALS withdrawal · 2019-02-12Clinical Trial Update: Image Guided Intensity Modulated Reirradiation (IG-IMRT) With Cetuximab for Locoregionally Confined Recurrent Head and Neck Squamous Cell Carcinoma [Phase 2]
A Phase 2 trial evaluating image-guided IMRT with cetuximab for locoregionally confined recurrent head and neck squamous cell carcinoma has …
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CLINICAL_TRIALS trial_result · 2019-02-05Clinical Trial Update: Cisplatin and Docetaxel Plus Docetaxel and Radiotherapy With Amifostine for Squamous Cell Carcinoma of the Head and Neck [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating cisplatin, docetaxel, radiotherapy, and amifostine for head and neck squamous cell carcinoma has compl…
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CLINICAL_TRIALS trial_result · 2019-01-18Clinical Trial Update: Chemoradiotherapy HNSCC, Randomized Study, Docetaxel,Cisplatin, 5FU,Erbitux. [Phase 3]
A Phase 3 randomized trial evaluating chemoradiotherapy with docetaxel, cisplatin, 5-fluorouracil, and cetuximab for head and neck squamous …
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CLINICAL_TRIALS trial_result · 2019-01-07Clinical Trial Update: Patritumab With Cetuximab and a Platinum Agent for Squamous Cell Carcinoma (Cancer) of the Head and Neck (SCCHN ) [Phase 2]
Phase 2 trial investigating patritumab with cetuximab and a platinum agent for head and neck squamous cell carcinoma has been terminated; re…