Head and Neck Squamous Cell Carcinoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2024-11-21Clinical Trial Update: Preoperative Immune Checkpoint Inhibitor for Patients With Primary Untreated or Recurrent/Metastatic SCCHN [Phase 2]
A Phase 2 trial evaluating a preoperative immune checkpoint inhibitor in patients with primary untreated or recurrent/metastatic head and ne…
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CLINICAL_TRIALS research · 2024-11-21Clinical Trial Update: Neoadjuvant Therapy of Targeted Immunotherapy Combined With Chemotherapy for Locally Advanced HNSCC [Phase 2]
Phase 2 neoadjuvant trial evaluating targeted PD-L1 immunotherapy combined with chemotherapy for locally advanced head and neck squamous cel…
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CLINICAL_TRIALS research · 2024-11-21Clinical Trial Update: Deep sequencIng in Cutaneous Squamous CEll caRciNomas [Phase 2]
Phase 2 clinical trial update exploring deep sequencing in cutaneous squamous cell carcinoma and cutaneous squamous cell carcinoma of the he…
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CLINICAL_TRIALS research · 2024-11-20Clinical Trial Update: Afatinib in Patients with Fanconi Anemia (FA) and Advanced Head and Neck Squamous Cell Carcinoma (HNSCC) [Phase 1, Phase 2]
A phase 1/2 clinical trial evaluating afatinib for patients with Fanconi anemia and advanced head and neck squamous cell carcinoma is curren…
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CLINICAL_TRIALS other · 2024-11-19Clinical Trial Update: Pembrolizumab in Combination with Flutamide Treatment for Recurrence / Metastasis HNSCC [Phase 2]
Phase 2 clinical trial evaluating pembrolizumab in combination with flutamide for recurrent or metastatic head and neck squamous cell carcin…
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CLINICAL_TRIALS research · 2024-11-18Clinical Trial Update: Study of Cemiplimab - TP Induction Chemotherapy in Patients with Locally Advanced Squamous Cell Carcinoma of the Head and Neck [Phase 1]
This Phase 1 trial is evaluating cemiplimab in combination with TP induction chemotherapy for locally advanced head and neck squamous cell c…
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CLINICAL_TRIALS trial_result · 2024-11-14Clinical Trial Update: A Phase 3 Study of AK112 Plus AK117 Versus Pembrolizumab in Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma (R/M HNSCC) [Phase 3]
A Phase 3 trial evaluating AK112 plus AK117 versus pembrolizumab for recurrent or metastatic head and neck squamous cell carcinoma; the stud…
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CLINICAL_TRIALS research · 2024-11-12Clinical Trial Update: Phase II Trial of Pembrolizumab in Recurrent or Metastatic HNSCC [Phase 2]
A Phase II trial evaluating pembrolizumab for recurrent or metastatic head and neck squamous cell carcinoma is currently active but not recr…
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CLINICAL_TRIALS research · 2024-11-08Clinical Trial Update: Prospective Pilot Study Evaluating Dental Side Effects of Radiotherapy on Subjects Treated for Head and Neck Cancer [Phase 2]
A Phase 2 prospective pilot trial is investigating dental side effects from radiotherapy in head and neck cancer patients, sponsored by Jule…
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CLINICAL_TRIALS trial_result · 2024-11-05Clinical Trial Update: Phase Ib Study of BKM120 With Cisplatin and XRT in High Risk Locally Advanced Squamous Cell Cancer of Head and Neck [Phase 1]
Phase Ib trial of buparlisib (BKM120) with cisplatin and radiotherapy in high-risk locally advanced squamous cell carcinoma of the head and …
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CLINICAL_TRIALS trial_result · 2024-10-31Clinical Trial Update: Safety and Efficacy of SB 11285 Alone and in Combination With Atezolizumab in Patients With Advanced Solid Tumors [Phase 1]
This is a Phase 1 trial update evaluating SB 11285 alone and in combination with atezolizumab in patients with advanced solid tumors, includ…
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CLINICAL_TRIALS research · 2024-10-31Clinical Trial Update: Skeletal Muscle Mass Changes on Images for Prediction of Prognosis After Exercise Training in HNSCC Patients [NA]
This clinical trial is currently recruiting to investigate whether changes in skeletal muscle mass measured on imaging can predict prognosis…
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CLINICAL_TRIALS trial_result · 2024-10-30Clinical Trial Update: Ruxolitinib in Operable Head and Neck Cancer [Phase 2]
A Phase 2 trial evaluating ruxolitinib in operable head and neck squamous cell carcinoma was terminated, with results posted on 2024-10-30.
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CLINICAL_TRIALS research · 2024-10-29Clinical Trial Update: Arabic PRO Measures for Head and Neck Cancer Radiotherapy.
A trial investigating Arabic patient-reported outcome measures for radiotherapy in head and neck cancer patients; currently recruiting.
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CLINICAL_TRIALS trial_result · 2024-10-29Clinical Trial Update: Image-guided Proton Therapy for the Treatment of Locally Advanced Unresectable Head and Neck Cancer [Phase 1]
This Phase 1 trial update reports the completion of a study evaluating image-guided proton therapy for locally advanced unresectable head an…
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CLINICAL_TRIALS research · 2024-10-26Clinical Trial Update: Study on the Efficacy of Treatment by Radiotherapy and Pembrolizumab in Newly Diagnosed Metastatic Head & Neck Cancers [Phase 3]
Phase 3 trial evaluating whether adding pembrolizumab to radiotherapy improves outcomes for newly diagnosed metastatic head and neck squamou…
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CLINICAL_TRIALS trial_result · 2024-10-23Clinical Trial Update: Study of INBRX-105 and INBRX-105 With Pembrolizumab in Patients With Solid Tumors Including Head and Neck Cancer [Phase 1]
This Phase 1 trial update reports termination of the INBRX-105 in combination with pembrolizumab across multiple solid tumors, including hea…
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CLINICAL_TRIALS research · 2024-10-18Clinical Trial Update: Neoadjuvant Toripalimab + Chemotherapy ± Cetuximab in Locally Advanced Head and Neck Squamous Cell Carcinoma (Neo-ICT) [Phase 3]
This is a Phase 3 trial evaluating neoadjuvant toripalimab plus chemotherapy with or without cetuximab for locally advanced head and neck sq…
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CLINICAL_TRIALS trial_result · 2024-10-18Clinical Trial Update: A Study of Pembrolizumab (MK-3475) With or Without Lenvatinib (E7080/MK-7902) as First Line (1L) Intervention in a Programmed Cell Death-ligand 1 (PD-L1) Selected Population With Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma (R/M HNSCC) (MK-7902-010/LEAP-010)-China Extension [Phase 3]
Phase 3 trial evaluating pembrolizumab with or without lenvatinib as first-line therapy in PD-L1–selected recurrent or metastatic head and n…
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CLINICAL_TRIALS trial_result · 2024-10-15Clinical Trial Update: Multi-Site Pathological Images-Guided ViT for Oral Squamous Cell Carcinoma Recurrence Prediction
A completed multi-site clinical trial evaluating a pathological images-guided ViT model to predict recurrence in oral squamous cell carcinom…
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CLINICAL_TRIALS research · 2024-10-15Clinical Trial Update: A Study of Pembrolizumab (MK-3475) Plus Platinum and Gemcitabine as First Line Treatment of Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma (PIPER) [Phase 2]
Phase 2 clinical trial (PIPER) evaluating pembrolizumab plus platinum and gemcitabine as first-line therapy for recurrent/metastatic head an…
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CLINICAL_TRIALS trial_result · 2024-10-10Clinical Trial Update: Study of NGM831 as Monotherapy and in Combination With Pembrolizumab or Pembrolizumab and NGM438 in Advanced or Metastatic Solid Tumors [Phase 1]
A Phase 1 study of NGM831 as a monotherapy and in combination with pembrolizumab (with or without NGM438) in advanced or metastatic solid tu…
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CLINICAL_TRIALS research · 2024-09-24Clinical Trial Update: A Study of SPX-303, a Bispecific Antibody Targeting LILRB2 and PD-L1 in Patients With Solid Tumors [Phase 1]
Describes a Phase 1 clinical trial of SPX-303, a bispecific antibody targeting LILRB2 and PD-L1, in patients with solid tumors, including he…
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CLINICAL_TRIALS research · 2024-09-23Clinical Trial Update: Image-Based, In-Vivo Assessment of Tumor Hypoxia to Guide Hypoxia-Driven Adaptive Radiation Therapy [EARLY_Phase 1]
A phase 1 study from Vanderbilt-Ingram Cancer Center is evaluating image-based, in-vivo assessment of tumor hypoxia to guide hypoxia-driven …
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CLINICAL_TRIALS trial_result · 2024-09-19Clinical Trial Update: Intensity-Modulated Radiation Therapy & Nivolumab for Recurrent or Second Primary Head & Neck Squamous Cell Cancer [Phase 2]
A Phase 2 study evaluating the combination of intensity-modulated radiation therapy with nivolumab for recurrent or second primary head and …