Head and Neck Squamous Cell Carcinoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2025-01-13Clinical Trial Update: Adjuvant De-Escalated Radiation + Adjuvant Nivolumab for Intermediate-High Risk P16+ Oropharynx Cancer [Phase 2]
Phase 2 trial evaluating de-escalated adjuvant radiation with adjuvant nivolumab in intermediate-high risk HPV-positive oropharyngeal squamo…
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CLINICAL_TRIALS research · 2025-01-13Clinical Trial Update: Nano-crystalline Megestrol Acetate for Adjuvant Treatment in High-risk Head and Neck Squamous Cell Carcinoma After Surgery. [Phase 3]
A Phase 3 trial evaluating adjuvant nano-crystalline megestrol acetate for high-risk head and neck squamous cell carcinoma after surgery; th…
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CLINICAL_TRIALS research · 2025-01-10Clinical Trial Update: A Value-Driven Study on Reducing Immune Checkpoint Inhibitor Dosing Frequency in Advanced Cancers [Phase 2]
This Phase 2 trial aims to evaluate whether reducing the dosing frequency of immune checkpoint inhibitors is feasible across advanced cancer…
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CLINICAL_TRIALS research · 2025-01-10Clinical Trial Update: Hypofractionated Radiotherapy for HNSCC in Elderly Patients [NA]
This clinical trial update indicates a study evaluating hypofractionated radiotherapy for head and neck squamous cell carcinoma in elderly p…
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CLINICAL_TRIALS trial_result · 2025-01-08Clinical Trial Update: Pepinemab in Combination With Pembrolizumab in Recurrent or Metastatic Squamous Cell Carcinoma of the Head and Neck [Phase 1, Phase 2]
A completed Phase 1/2 trial evaluating pepinemab in combination with pembrolizumab in recurrent or metastatic head and neck squamous cell ca…
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CLINICAL_TRIALS research · 2025-01-01Clinical Trial Update: Application of MRI Radiomics Features in Neoadjuvant Therapy of Head and Neck Squamous Cell Carcinoma
A clinical trial protocol evaluating MRI radiomics features to predict response to neoadjuvant therapy in head and neck squamous cell carcin…
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CLINICAL_TRIALS research · 2025-01-01Clinical Trial Update: Using a 3D Culture Model for Circulating Tumor Cells Combined With Molecular Bioassays in Patients With HNSCC Cancer
A clinical trial update describing a study that uses a 3D culture model for circulating tumor cells combined with molecular bioassays in pat…
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CLINICAL_TRIALS research · 2024-12-31Clinical Trial Update: Bone Marrow Protective Effect of Trilaciclib in Postoperative CCRT for LA-HNSCC [Phase 2]
Phase 2 clinical trial update exploring trilaciclib as a bone marrow protective agent during postoperative concurrent chemoradiation for loc…
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CLINICAL_TRIALS trial_result · 2024-12-27Clinical Trial Update: Pembrolizumab & Cabozantinib in Patients With Head and Neck Squamous Cell Cancer [Phase 2]
Phase 2 trial evaluating the combination of pembrolizumab and cabozantinib in head and neck squamous cell carcinoma reported results, with r…
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CLINICAL_TRIALS trial_result · 2024-12-20Clinical Trial Update: Safety, Tolerability, and Preliminary Efficacy of CJRB-101 With Pembrolizumab in Subjects With Selected Types of Advanced or Metastatic Cancer [Phase 1, Phase 2]
Phase 1/2 study assessing safety, tolerability, and preliminary efficacy of CJRB-101 in combination with pembrolizumab in selected advanced …
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CLINICAL_TRIALS research · 2024-12-19Clinical Trial Update: A Clinical Study on Neoadjuvant Treatment of Resectable Head and Neck Squamous Carcinoma With Immune-targeted Therapy and Lysogenic HSV Virus [Phase 1]
Phase 1 neoadjuvant trial assessing an immune-targeted therapy in combination with a lysogenic HSV virus for resectable head and neck squamo…
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CLINICAL_TRIALS trial_result · 2024-12-18Clinical Trial Update: Combination Study With Soluble LAG-3 Fusion Protein Eftilagimod Alpha (IMP321) and Pembrolizumab in Patients With Previously Untreated Unresectable or Metastatic NSCLC, or Recurrent PD-X Refractory NSCLC or With Recurrent or Metastatic HNSCC [Phase 2]
A Phase 2 trial evaluated the combination of eftilagimod alpha (IMP321) with pembrolizumab in patients with previously untreated unresectabl…
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CLINICAL_TRIALS research · 2024-12-17Clinical Trial Update: Safety and Efficacy of VB10.16 and Pembrolizumab in Patients with Head-Neck Squamous Cell Carcinoma [Phase 1, Phase 2]
A Phase 1/2 trial evaluating VB10.16 in combination with pembrolizumab for HPV-positive oropharyngeal squamous cell carcinoma and head-and-n…
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CLINICAL_TRIALS trial_result · 2024-12-17Clinical Trial Update: A CR-UK Phase I Trial of LY3143921 [Phase 1]
Phase I trial update for LY3143921 sponsored by Cancer Research UK; the study is Active Not Recruiting and explores multiple cancer indicati…
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CLINICAL_TRIALS trial_result · 2024-12-16Clinical Trial Update: Alisertib and Pembrolizumab for the Treatment of Patients With Rb-deficient Head and Neck Squamous Cell Cancer [Phase 1, Phase 2]
A completed Phase 1/2 trial evaluated the combination of alisertib and pembrolizumab in RB-deficient head and neck squamous cell carcinoma; …
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CLINICAL_TRIALS research · 2024-12-13Clinical Trial Update: Testing the Addition of an Anti-cancer Drug, BAY 1895344, With Radiation Therapy to the Usual Pembrolizumab Treatment for Recurrent Head and Neck Cancer [Phase 1]
Phase 1 study evaluating adding BAY 1895344 with radiation therapy to pembrolizumab for recurrent head and neck squamous cell carcinomas, ai…
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CLINICAL_TRIALS research · 2024-12-10Clinical Trial Update: HNSCC Immuno-genomics Project
A completed clinical trial update describing a project focused on immunogenomics and molecular classification of head and neck squamous cell…
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CLINICAL_TRIALS research · 2024-12-10Clinical Trial Update: The Value of CEUS in Assessing the Response of Cervical Lymph Nodes After NACI for HNSCC
Clinical trial update on using contrast-enhanced ultrasound to assess cervical lymph node response after neoadjuvant therapy in head and nec…
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CLINICAL_TRIALS research · 2024-12-10Clinical Trial Update: Intra-arterial Chemotherapy Combined with Radiotherapy and Immunotherapy for HNSCC [Phase 2]
A Phase 2 clinical trial is evaluating intra-arterial chemotherapy combined with radiotherapy and immunotherapy for head and neck squamous c…
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CLINICAL_TRIALS trial_result · 2024-12-09Clinical Trial Update: Efficacy and Safety of a Third-Course of Neoadjuvant Immunochemotherapy Combined With SBRT in Locally Advanced Head and Neck Squamous Cell Carcinoma Patients With Stable Disease After Two Treatment Courses: A Single-Arm Exploratory Study [NA]
Clinical trial update on the efficacy and safety of a third course of neoadjuvant immunochemotherapy combined with SBRT for locally advanced…
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CLINICAL_TRIALS research · 2024-12-09Clinical Trial Update: Study of TL117 in Patients With Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma [Phase 1, Phase 2]
Clinical trial update for TL117 in recurrent or metastatic head and neck squamous cell carcinoma (Phase 1/Phase 2); the study is currently a…
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CLINICAL_TRIALS research · 2024-12-05Clinical Trial Update: A Clinical Trial to Evaluate Effect of IAE0972 Combined with Chemotherapy for R/M HNSCC or NPC(Note: It is Currently Phase II.). [Phase 2, Phase 3]
A clinical trial evaluating the effect of IAE0972 in combination with chemotherapy for recurrent/metastatic head and neck squamous cell carc…
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CLINICAL_TRIALS research · 2024-12-03Clinical Trial Update: Trilaciclib in Preventing Hematopoietic Suppression in Patients with Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma [Phase 2]
A Phase 2 clinical trial evaluating trilaciclib to prevent chemotherapy-induced hematopoietic suppression in patients with recurrent or meta…
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CLINICAL_TRIALS research · 2024-12-03Clinical Trial Update: Patient-derived Xenograft Models of Tumor From Patients With Head and Neck Cancer
This clinical trial focuses on establishing patient-derived xenograft models using tumors from patients with head and neck squamous cell car…
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CLINICAL_TRIALS other · 2024-12-02Clinical Trial Update: A Phase II Study of Neoadjuvant Immunotherapy in Combination With Chemotherapy in Locally Advanced Head and Neck Squamous Cell Carcinoma [Phase 2]
Phase II study of neoadjuvant immunotherapy in combination with chemotherapy for locally advanced head and neck squamous cell carcinoma, cur…