Head and Neck Squamous Cell Carcinoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2025-02-17Clinical Trial Update: Study of ALE.C04 in Patients With Head and Neck Cancer [Phase 1, Phase 2]
The Phase 1/Phase 2 study of ALE.C04 for head and neck cancer has been terminated.
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CLINICAL_TRIALS research · 2025-02-17Clinical Trial Update: Personalized Nutrition Counseling and Nutritional Status of Esophageal Cancer and HNSCC Patients Undergoing CCRT
A clinical trial update indicates that a study evaluating personalized nutrition counseling and nutritional status in esophageal cancer and …
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CLINICAL_TRIALS withdrawal · 2025-02-14Clinical Trial Update: NT-I7 for the Treatment of Recurrent Squamous Cell Carcinoma of Head and Neck Undergoing Surgery [Phase 1]
A Phase 1 trial of NT-I7 for recurrent squamous cell carcinoma of the head and neck undergoing surgery was terminated.
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CLINICAL_TRIALS trial_result · 2025-02-12Clinical Trial Update: Celecoxib Through Surgery and Radiation Therapy for the Treatment of Advanced Head and Neck Cancer [Phase 2]
Phase 2 trial evaluating celecoxib added to surgery and radiation for advanced head and neck cancer; the study was terminated with results p…
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CLINICAL_TRIALS research · 2025-02-12Clinical Trial Update: Efficacy of an Oral Immunomodulatory Nutrient on Survival During Postoperative Concomitant Chemoradiotherapy in Head and Neck Cancer [NA]
This clinical trial update describes an oral immunomodulatory nutrient being studied for survival during postoperative concomitant chemoradi…
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CLINICAL_TRIALS trial_result · 2025-02-11Clinical Trial Update: Onalespib in Treating Patients With Locoregionally Advanced Squamous Cell Carcinoma of the Head and Neck Receiving Radiation Therapy and Cisplatin [Phase 1]
Phase 1 trial evaluating the safety and tolerability of Onalespib in combination with radiation therapy and cisplatin for locoregionally adv…
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CLINICAL_TRIALS research · 2025-02-11Clinical Trial Update: Tirilizumab with Albumin-bound Paclitaxel and Cisplatin for Locally Advanced Resectable Oral Squamous Cell Carcinoma [Phase 2]
A Phase 2 clinical trial is evaluating tirilizumab in combination with albumin-bound paclitaxel and cisplatin for locally advanced resectabl…
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CLINICAL_TRIALS trial_result · 2025-02-10Clinical Trial Update: A Safety Study of SEA-TGT (SGN-TGT) in Advanced Cancer [Phase 1]
Seagen's SEA-TGT (SGN-TGT) Phase 1 safety study in advanced cancers has been terminated. The study enrolled patients across multiple cancer …
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CLINICAL_TRIALS trial_result · 2025-02-07Clinical Trial Update: Phase II Multi-centered Study of Perioperative Ivonescimab Versus Pembrolizumab Combined with Standard of Care (SOC) in Patients with Resectable, Locally Advanced Head and Neck Squamous Cell Carcinoma [Phase 2]
Phase II multi-center study comparing perioperative Ivonescimab to Pembrolizumab plus standard of care in patients with resectable, locally …
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CLINICAL_TRIALS research · 2025-02-07Clinical Trial Update: Specific Methylation Profiles in HNSCC
This clinical trial update reports on a study at Aalborg University Hospital investigating methylation profiles in head and neck squamous ce…
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CLINICAL_TRIALS research · 2025-02-07Clinical Trial Update: Reconstruction of Cervical Lymphatic System During Head and Neck Squamous Cell Carcinoma Surgery [NA]
Registry entry for a prospective study on reconstructing the cervical lymphatic system during head and neck squamous cell carcinoma surgery,…
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CLINICAL_TRIALS research · 2025-02-05Clinical Trial Update: PA.RI.GE. Study. The Prognostic Role of Inflammatory Circulating Biomarkers in HNSCC: a Prospective Multicentric Trial
This clinical trial studies the prognostic role of inflammatory circulating biomarkers in head and neck squamous cell carcinoma and is curre…
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CLINICAL_TRIALS other · 2025-02-04Clinical Trial Update: Impact of the Oral Microbiota on Relapse in HNSCC Patients [Phase 4]
Phase 4 clinical trial investigating the impact of the oral microbiota on relapse in patients with head and neck cancer, currently active bu…
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CLINICAL_TRIALS trial_result · 2025-02-03Clinical Trial Update: Phase 1 Study of CK-301 (Cosibelimab) as a Single Agent in Subjects With Advanced Cancers [Phase 1]
Phase 1 study of cosibelimab (CK-301) as a single-agent therapy in adults with advanced cancers; the trial status is active but not recruiti…
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CLINICAL_TRIALS trial_result · 2025-02-03Clinical Trial Update: Radiotherapy in Combination With Atezolizumab Prior to Surgical Resection for HPV Unrelated HNSCC [Phase 1]
Phase 1 trial evaluating radiotherapy in combination with atezolizumab prior to surgical resection for HPV-unrelated head and neck squamous …
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CLINICAL_TRIALS trial_result · 2025-01-29Clinical Trial Update: Navigation vs Usual Care for Timely Adjuvant Therapy for Patients With Locally Advanced HNSCC [NA]
Clinical trial update comparing navigation to usual care for delivering timely adjuvant therapy in locally advanced head and neck squamous c…
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CLINICAL_TRIALS research · 2025-01-29Clinical Trial Update: A Study of Bispecific Antibody MCLA-158 in Patients With Advanced Solid Tumors [Phase 1, Phase 2]
This clinical trial update describes a Phase 1/2 study of the bispecific antibody MCLA-158 in patients with advanced solid tumors. Recruitme…
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CLINICAL_TRIALS research · 2025-01-29Clinical Trial Update: A Phase I/IIa Clinical Trial to Investigate BVAC-E6E7 in Subjects with HPV Positive HNSCC. [Phase 1, Phase 2]
This clinical trial update reports a Phase 1/2a study evaluating BVAC-E6E7 in HPV-positive head and neck squamous cell carcinoma, with the t…
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CLINICAL_TRIALS research · 2025-01-28Clinical Trial Update: Study of Pembrolizumab Combined with Chemotherapy in the First Line Therapy for R/M HNSCC in China [Phase 2]
Phase 2 clinical trial evaluating pembrolizumab combined with chemotherapy as first-line therapy for recurrent/metastatic head and neck squa…
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CLINICAL_TRIALS trial_result · 2025-01-24Clinical Trial Update: The Use of "Smart" Body-Weight Scales for Weight and Nutritional Monitoring in Patients With Head and Neck Cancer Undergoing Radiation Therapy [NA]
Clinical trial NCT05457478 evaluating the use of smart body-weight scales for weight and nutritional monitoring in head and neck squamous ce…
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CLINICAL_TRIALS other · 2025-01-21Clinical Trial Update: A Study of Evofosfamide in Combination with Zalifrelimab and Balstilimab [Phase 1, Phase 2]
A Phase 1/2 study of evofosfamide in combination with zalifrelimab and balstilimab is currently recruiting for metastatic prostate cancer, m…
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CLINICAL_TRIALS research · 2025-01-20Clinical Trial Update: PBI-MST-01 (NCT04541108) Substudy AZN-05: Intratumoral Microdosing of Rilvegostomig, Volrustomig, Sabestomig, and AZD9592 in HNSCC [EARLY_Phase 1]
This early-phase trial update shows that the PBI-MST-01 substudy AZN-05 is recruiting intratumoral microdosing of four investigational agent…
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CLINICAL_TRIALS trial_result · 2025-01-17Clinical Trial Update: Dose Escalation Using Hypoxia-adjusted Radiotherapy [Phase 2]
Phase 2 trial evaluating dose escalation with hypoxia-adjusted radiotherapy in head and neck squamous cell carcinoma is currently recruiting…
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CLINICAL_TRIALS research · 2025-01-15Clinical Trial Update: Study of TPEx Followed by a Maintenance With Avelumab and Cetuximab in First Line Recurrent or Metastatic Squamous Cell Carcinoma of the H&N [Phase 2]
This Phase 2 trial investigates TPEx chemotherapy followed by maintenance with avelumab and cetuximab as first-line treatment for recurrent …
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CLINICAL_TRIALS trial_result · 2025-01-14Clinical Trial Update: Immunotherapy in Combination With Chemoradiation in Patients With Advanced Solid Tumors [Phase 1]
A Phase 1 trial update reports completion of a study evaluating an immunotherapy in combination with chemoradiation for advanced solid tumor…