Head and Neck Squamous Cell Carcinoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-03-25Clinical Trial Update: Special Care Patterns for Elderly HNSCC Patients Undergoing Radiotherapy
A clinical trial is recruiting elderly patients with head and neck squamous cell carcinoma undergoing radiotherapy. The study covers cancers…
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CLINICAL_TRIALS trial_result · 2025-03-21Clinical Trial Update: Efficacy of Tislelizumab and Spartalizumab Across Multiple Cancer-types in Patients with PD1-high MRNA Expressing Tumors [Phase 2]
Phase 2 study evaluating the efficacy of tislelizumab and spartalizumab across multiple cancers with PD-1 high mRNA expression; the trial is…
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CLINICAL_TRIALS trial_result · 2025-03-21Clinical Trial Update: Oral STAT3 Inhibitor, TTI-101, in Patients With Advanced Cancers [Phase 1]
Phase 1 study of the oral STAT3 inhibitor TTI-101 in patients with advanced cancers has completed, with enrollment across multiple tumor typ…
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CLINICAL_TRIALS trial_result · 2025-03-21Clinical Trial Update: Intratumoral Gemcitabine, Paclitaxel, Carboplatine and Intravenous Nivolumab for Locally Recurrence of Head and Neck Cancers [Phase 2]
Phase 2 trial update for intratumoral gemcitabine, paclitaxel, and carboplatin with intravenous nivolumab in locally recurrent head and neck…
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CLINICAL_TRIALS trial_result · 2025-03-19Clinical Trial Update: Group-Mediated Cognitive Behavioral Resistance Exercise Intervention in Head and Neck Cancer Patients Undergoing Chemoradiation Treatment [NA]
A clinical trial evaluating a group-mediated cognitive behavioral resistance exercise intervention for locally advanced head and neck squamo…
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CLINICAL_TRIALS trial_result · 2025-03-18Clinical Trial Update: Erlotinib (Tarceva) During First Line Standard Platinum Containing Chemo for Advanced Squamous Cell Head and Neck Cancer [Phase 2, Phase 3]
Phase 2/3 trial evaluating erlotinib (Tarceva) with first-line platinum-containing chemotherapy for advanced head and neck squamous cell car…
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CLINICAL_TRIALS trial_result · 2025-03-17Clinical Trial Update: Tolinapant and Radiation for Cisplatin-Ineligible, Previously Untreated, Locally Advanced Head and Neck Cancer [EARLY_Phase 1]
Early-phase trial evaluating Tolinapant in combination with radiation for cisplatin-ineligible, previously untreated locally advanced head a…
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CLINICAL_TRIALS research · 2025-03-17Clinical Trial Update: Chemo-Radiotherapy Boost Treatment Guided by Perfusion MRI on Hypoxic Zones in Head and Neck Cancer [Phase 2]
Phase 2 clinical trial evaluating a chemo-radiotherapy boost guided by perfusion MRI of hypoxic zones in head and neck squamous cell carcino…
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CLINICAL_TRIALS research · 2025-03-17Clinical Trial Update: A Trial of Nimotuzumab and Pinkiller Efficacy and Pain in Advanced Head and Neck Squamous Cell Carcinoma [Phase 4]
A Phase 4 trial of Nimotuzumab with Pinkiller for advanced head and neck squamous cell carcinoma is ongoing. The study is currently active b…
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CLINICAL_TRIALS research · 2025-03-14Clinical Trial Update: Surufatinib Combined with Envolizumab As Second-line Treatment for Recurrent/Metastatic HNSCC [Phase 2]
A Phase 2 trial evaluating surufatinib in combination with envolizumab as second-line treatment for recurrent/metastatic head and neck cance…
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CLINICAL_TRIALS research · 2025-03-14Clinical Trial Update: Cetuximab Plus Platinum and Taxane-based Chemotherapy, Followed by Avelumab and Cetuximab, as First-line Treatment for Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma (HNSCC) Patients With a PD-L1 Combined Positive Score (CPS)≥1≤19. [Phase 2]
Phase 2 clinical trial evaluating cetuximab with platinum and taxane-based chemotherapy followed by avelumab and cetuximab as first-line tre…
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CLINICAL_TRIALS research · 2025-03-13Clinical Trial Update: Neoadjuvant Immunochemotherapy for LAOSCC [Phase 3]
A Phase 3 clinical trial investigating neoadjuvant immunochemotherapy for locally advanced oral squamous cell carcinoma and head and neck sq…
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CLINICAL_TRIALS research · 2025-03-13Clinical Trial Update: Two-cohort Study of Niraparib and Dostarlimab Plus (Chemo)RadIotherapy in Locally-Advanced Head and Neck Squamous Cell Carcinoma [Phase 1, Phase 2]
A two-cohort phase 1/2 clinical trial is investigating niraparib and dostarlimab with chemotherapy and radiotherapy in locally advanced head…
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CLINICAL_TRIALS trial_result · 2025-03-12Clinical Trial Update: A Comparison of NETSPOT Imaging Versus F-FDG-PET in Head and Neck Cancer Patients [Phase 2]
Phase 2 trial comparing NETSPOT imaging (gallium-68 DOTATATE) with standard F-FDG-PET for detecting head and neck squamous cell carcinoma; r…
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CLINICAL_TRIALS withdrawal · 2025-03-11Clinical Trial Update: Study of RP3 in Combination With Nivolumab and Other Therapy in Patients With Locoregionally Advanced or Recurrent SCCHN [Phase 2]
A Phase 2 trial evaluating RP3 in combination with Nivolumab and other therapy for locoregionally advanced or recurrent head and neck squamo…
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CLINICAL_TRIALS trial_result · 2025-03-10Clinical Trial Update: A Study of Ladiratuzumab Vedotin in Advanced Solid Tumors [Phase 2]
Phase 2 trial of ladiratuzumab vedotin in multiple advanced solid tumors was terminated, with results posted in March 2025.
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CLINICAL_TRIALS trial_result · 2025-03-10Clinical Trial Update: A Study of TBio-4101 (TIL) and Pembrolizumab in Patients With Advanced Solid Tumors [Phase 1]
Phase 1 study of TBio-4101 (TIL) with pembrolizumab in advanced solid tumors has been terminated; the trial includes multiple indications su…
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CLINICAL_TRIALS trial_result · 2025-03-06Clinical Trial Update: Reirradiation With Pembrolizumab in Locoregional Inoperable Recurrence or Second Primary Squamous Cell CA of the Head and Neck [Phase 2]
Phase 2 trial evaluating reirradiation with pembrolizumab for locoregional inoperable recurrence or second primary head and neck squamous ce…
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CLINICAL_TRIALS trial_result · 2025-03-05Clinical Trial Update: Duvelisib Plus Docetaxel In Recurrent/Metastatic HNSCC [Phase 2]
Phase 2 study update on adding duvelisib to docetaxel for recurrent/metastatic head and neck squamous cell carcinoma; the trial has complete…
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CLINICAL_TRIALS research · 2025-02-25Clinical Trial Update: Induction IBI110 and Sintilimab with Chemotherapy in LA HNSCC [Phase 1, Phase 2]
This is a Phase 1/2 clinical trial sponsored by Fudan University evaluating induction with IBI110 and Sintilimab in combination with chemoth…
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CLINICAL_TRIALS research · 2025-02-25Clinical Trial Update: Exercise Therapy in Head and Neck Squamous Cell Carcinoma (HNSCC) [NA]
This clinical trial registration describes a study evaluating exercise therapy for head and neck squamous cell carcinoma (HNSCC); the trial …
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CLINICAL_TRIALS trial_result · 2025-02-24Clinical Trial Update: sEphB4-HSA With RT+Chemo or Cetux in Patients With Intermediate to High Risk LAHNSCC [Phase 1]
This is a Phase 1 trial evaluating sEphB4-HSA with radiotherapy plus chemotherapy or cetuximab in locally advanced head and neck squamous ce…
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CLINICAL_TRIALS withdrawal · 2025-02-24Clinical Trial Update: QUILT-3.047: NANT Head and Neck Squamous Cell Carcinoma (HNSCC) Vaccine: Combination Immunotherapy in Subjects With HNSCC Who Have Progressed on or After Chemotherapy and PD-1/PD-L1 Therapy [Phase 1, Phase 2]
The QUILT-3.047 trial evaluating ImmunityBio's NANT vaccine for head and neck squamous cell carcinoma has been withdrawn.
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CLINICAL_TRIALS research · 2025-02-20Clinical Trial Update: Identifying the Predictive Factors of Response to PD-1 or PD-L1 Antagonists [NA]
A clinical trial update aimed at identifying predictive factors of response to PD-1/PD-L1 inhibitors across multiple cancers, including mela…
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CLINICAL_TRIALS trial_result · 2025-02-19Clinical Trial Update: Efficacy of Immunotherapy Plus a Drug in Patients With Progressive Advanced Mucosal Cancer of Different Locations [Phase 2]
A completed Phase 2 trial evaluating immunotherapy in combination with a second drug in patients with progressive advanced mucosal cancers a…