Head and Neck Squamous Cell Carcinoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-07-23Clinical Trial Update: VX15/2503 in Combination With Ipilimumab or Nivolumab in Patients With Head and Neck Cancer [Phase 1]
Phase 1 trial evaluating VX15/2503 in combination with ipilimumab or nivolumab for head and neck squamous cell carcinoma; currently recruiti…
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CLINICAL_TRIALS research · 2025-07-22Clinical Trial Update: A Trial of SHR-A2102 With Adebrelimab With or Without Other Anti-tumor Therapies in Recurrent/MetastaticHead and Neck Squamous Cell Carcinoma Cancer [Phase 1, Phase 2]
Clinical trial update describes a Phase 1/2 study of SHR-A2102 combined with Adebrelimab, with or without other anti-tumor therapies, in rec…
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CLINICAL_TRIALS research · 2025-07-20Clinical Trial Update: d-Limonene +Radiation +PlatinumBasedChemo for Xerostomia Prevention in LocallyAdvanced HNSCC [Phase 1]
A Phase 1 clinical trial is evaluating the addition of d-Limonene to radiation and platinum-based chemotherapy to prevent xerostomia in pati…
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CLINICAL_TRIALS research · 2025-07-18Clinical Trial Update: Dalpicilib Plus Cetuximab Compared With Cetuximab Alone in HPV-negative, Anti-PD-1-resistant R/M HNSCC [Phase 2]
This is a Phase 2 trial comparing dalpicilib plus cetuximab versus cetuximab alone in HPV-negative, anti-PD-1-resistant recurrent/metastatic…
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CLINICAL_TRIALS trial_result · 2025-07-18Clinical Trial Update: NUC-3373 in Combination With Other Agents in Patients With Advanced Solid Tumours [Phase 1, Phase 2]
NuCana plc announced termination of a Phase 1/2 trial evaluating NUC-3373 in combination with other agents for patients with advanced solid …
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CLINICAL_TRIALS research · 2025-07-16Clinical Trial Update: 89Zr-Panitumumab for Assessment of Suspected Metastatic Lesions on 18F-FDG-PET/CT in HNSCC [Phase 2]
Phase 2 trial evaluating 89Zr-Panitumumab as an imaging agent to detect suspected metastatic lesions on 18F-FDG PET/CT in head and neck squa…
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CLINICAL_TRIALS research · 2025-07-15Clinical Trial Update: A Long-Term Follow-Up Study of Participants Treated With A2 Biotherapeutics (A2 Bio) Gene Therapy (GT) Products
This clinical trial update reports long-term follow-up of participants treated with A2 Biotherapeutics' gene therapy products in solid tumor…
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CLINICAL_TRIALS research · 2025-07-10Clinical Trial Update: Study of MEDI0562 Prior to Surgical Resection in Head and Neck Squamous Cell Carcinoma (HNSCC) or Melanoma [Phase 1]
This is a Phase 1 clinical trial evaluating MEDI0562 before surgical resection in head and neck squamous cell carcinoma or melanoma; the stu…
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CLINICAL_TRIALS trial_result · 2025-07-10Clinical Trial Update: 89Zr-girentuximab for PET Imaging of CAIX Positive Solid Tumors [Phase 2]
Telix's phase 2 trial of the CAIX-targeting PET tracer 89Zr-girentuximab in CAIX-positive solid tumors was terminated.
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CLINICAL_TRIALS withdrawal · 2025-07-10Clinical Trial Update: Study of Front Line Pembrolizumab and Valemetostat in PD-L1 Positive, HPV-Negative Recurrent/Metastatic Squamous Cell Carcinoma (SCC) of the Head and Neck: The PANTHERAS [Phase 1, Phase 2]
A Phase 1/2 study of frontline pembrolizumab plus valemetostat for PD-L1 positive, HPV-negative recurrent/metastatic squamous cell carcinoma…
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CLINICAL_TRIALS research · 2025-07-10Clinical Trial Update: Study Evaluating a Stereotactic Boost/Treatment for Recurrent or Metastatic Cancer of the Head and Neck [Phase 1]
Phase 1 trial evaluating a stereotactic boost/treatment for recurrent or metastatic head and neck cancer; the study is currently active but …
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CLINICAL_TRIALS research · 2025-07-10Clinical Trial Update: Neoadjuvant Immunoradiotherapy in Head & Neck Cancer [Phase 1, Phase 2]
This clinical trial update describes a Phase 1/2 neoadjuvant immunoradiotherapy study for head and neck cancer, currently active but not rec…
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CLINICAL_TRIALS research · 2025-07-09Clinical Trial Update: Single-Arm Exploratory Study of PD-L1 Antibody Plus Neoadjuvant Chemotherapy in Locally Advanced Head and Neck Squamous Cell Carcinoma [Phase 2]
A Phase 2, single-arm exploratory study evaluating a PD-L1–targeting antibody plus neoadjuvant chemotherapy for locally advanced head and ne…
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CLINICAL_TRIALS research · 2025-07-08Clinical Trial Update: A Study to Evaluate the Efficacy and Safety of MRG003 in Patients With Recurrent or Metastatic Squamous Cell Carcinoma of Head and Neck [Phase 2]
Phase 2 clinical trial evaluating the efficacy and safety of MRG003 in patients with recurrent or metastatic squamous cell carcinoma of the …
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CLINICAL_TRIALS research · 2025-07-08Clinical Trial Update: Comparing Two Surveillance Approaches for People Who Have Received Treatment for HPV-associated Head and Neck Cancer and Show No Signs of Disease [NA]
This clinical trial compares two surveillance approaches for people previously treated for HPV-associated head and neck squamous cell carcin…
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CLINICAL_TRIALS research · 2025-07-03Clinical Trial Update: Microbiota Transplant to Cancer Patients Who Have Failed Immunotherapy Using Faeces From Clinical Responders [Phase 2]
A Phase 2 clinical trial at Oslo University Hospital is testing fecal microbiota transplantation from clinical responders in cancer patients…
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CLINICAL_TRIALS trial_result · 2025-07-02Clinical Trial Update: A Study of Nivolumab in Patients With Head and Neck Cancer.
Clinical trial update noting the study of nivolumab in head and neck squamous cell carcinoma has completed.
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CLINICAL_TRIALS trial_result · 2025-07-01Clinical Trial Update: A Phase 1/2 Study of FS118 in Patients With Advanced Malignancies [Phase 1, Phase 2]
A Phase 1/2 study of FS118 in patients with advanced and metastatic cancers, including head and neck squamous cell carcinoma, has been termi…
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CLINICAL_TRIALS trial_result · 2025-07-01Clinical Trial Update: Pembrolizumab and Induction Chemotherapy in Locally Advanced HNSCC [Phase 2]
This clinical trial update reports a Phase 2 study evaluating pembrolizumab in combination with induction chemotherapy for locally advanced …
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CLINICAL_TRIALS trial_result · 2025-06-27Clinical Trial Update: Testing the Addition of M6620 (VX-970, Berzosertib) to Usual Chemotherapy and Radiation for Head and Neck Cancer [Phase 1]
Phase 1 trial evaluating the addition of M6620 (berzosertib; VX-970) to standard chemotherapy and radiation for head and neck cancers, inclu…
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CLINICAL_TRIALS research · 2025-06-27Clinical Trial Update: Iparomlimab and Tuvonralimab Combined With SFRT and Definitive Chemoradiotherapy in Locoregionally Advanced Bulky HNSCC [Phase 2]
Phase 2 clinical trial evaluating iparomlimab and tuvonralimab in combination with SFRT and definitive chemoradiotherapy for locoregionally …
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CLINICAL_TRIALS trial_result · 2025-06-26Clinical Trial Update: Study to Assess the Efficacy and Safety of Nivolumab in Combination With Paclitaxel in Subjects With Head and Neck Cancer Unable for Cisplatin-based Chemotherapy (NIVOTAX) [Phase 2]
Phase 2 trial evaluating nivolumab plus paclitaxel for recurrent/metastatic head and neck squamous cell carcinoma in patients unable to rece…
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CLINICAL_TRIALS research · 2025-06-26Clinical Trial Update: A Randomized Controlled Trial of Spermidine for the Prevention of Radiation-Induced Xerostomia in Head and Neck Squamous Cell Carcinoma (Including Nasopharyngeal Carcinoma) [Phase 1, Phase 2]
A phase 1/2 randomized trial evaluating spermidine to prevent radiation-induced xerostomia in patients with head and neck cancers, including…
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CLINICAL_TRIALS research · 2025-06-26Clinical Trial Update: Finotonlimab Combined With Stapokibart in the Treatment of Recurrent/Metastatic HNSCC [Phase 1]
Phase 1 clinical trial evaluating finotonlimab in combination with stapokibart for recurrent/metastatic head and neck squamous cell carcinom…
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CLINICAL_TRIALS research · 2025-06-25Clinical Trial Update: A Clinical Trail of KJ015 in Patients With HER2-Expressing Solid Tumors [Phase 1]
A Phase 1 trial update for KJ015 in HER2-expressing solid tumors shows the study is not yet recruiting.