Head and Neck Squamous Cell Carcinoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2025-10-03Clinical Trial Update: Safety and Preliminary Effectiveness of BGB-A445 in Combination With Tislelizumab in Participants With Advanced Solid Tumors [Phase 1]
This Phase 1 trial evaluated safety and preliminary effectiveness of BGB-A445 in combination with tislelizumab in participants with advanced…
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CLINICAL_TRIALS research · 2025-10-03Clinical Trial Update: Window Trial of Fluorescently Labeled Panitumumab (Panitumumab-IRDye800) in Head and Neck Cancer [EARLY_Phase 1]
This EARLY Phase 1 clinical trial update describes a window trial of the fluorescent Panitumumab-IRDye800 agent for imaging in head and neck…
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CLINICAL_TRIALS research · 2025-10-03Clinical Trial Update: Evaluating the Use of Dual Imaging Techniques for Detection of Disease in Patients With Head and Neck Cancer [Phase 1]
A Phase 1 clinical trial from Vanderbilt-Ingram Cancer Center is evaluating dual imaging techniques to detect disease in patients with head …
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CLINICAL_TRIALS research · 2025-10-03Clinical Trial Update: High-Resolution PET-CT Imaging for Surgical Margin Visualization [NA]
A clinical trial evaluating high-resolution PET-CT imaging to visualize surgical margins in head and neck cancers; the study is currently re…
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CLINICAL_TRIALS trial_result · 2025-10-02Clinical Trial Update: The Head and Neck Tumor Biobank
Clinical trial update for the Head and Neck Tumor Biobank (NCT01644786) sponsored by Maastricht Radiation Oncology; the study focusing on He…
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CLINICAL_TRIALS research · 2025-10-02Clinical Trial Update: Compartmentalized Postoperative Radiotherapy in Head and Neck Cancer [Phase 2]
A Phase 2 clinical trial evaluating compartmentalized postoperative radiotherapy in head and neck cancer, currently not yet recruiting.
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CLINICAL_TRIALS trial_result · 2025-10-01Clinical Trial Update: Study of PDS0101 and Pembrolizumab Combination I/O in Subjects With HPV16 + Recurrent and/or Metastatic HNSCC [Phase 2]
A Phase 2 trial evaluating the combination of PDS0101 and pembrolizumab in HPV16-positive recurrent/metastatic head and neck cancer has comp…
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CLINICAL_TRIALS trial_result · 2025-09-30Clinical Trial Update: A Study of Atezolizumab Plus Tiragolumab and Atezolizumab Plus Placebo as First-Line Treatment in Participants With Recurrent/Metastatic PD-L1 Positive Squamous Cell Carcinoma of the Head and Neck [Phase 2]
Completed Phase 2 trial comparing atezolizumab plus tiragolumab versus atezolizumab plus placebo as first-line treatment for PD-L1 positive …
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CLINICAL_TRIALS trial_result · 2025-09-30Clinical Trial Update: Phase Ib Study of TNO155 in Combination With Spartalizumab or Ribociclib in Selected Malignancies [Phase 1]
Phase Ib study of TNO155 in combination with Spartalizumab or Ribociclib in selected malignancies was terminated, involving multiple indicat…
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CLINICAL_TRIALS trial_result · 2025-09-29Clinical Trial Update: Phase 1b Safety Study of Xevinapant, Weekly Cisplatin, and RT in Participants With Unresected LA SCCHN (HyperlynX) [Phase 1]
Phase 1b safety study of Xevinapant with weekly cisplatin and radiotherapy in unresected locally advanced head and neck squamous cell carcin…
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CLINICAL_TRIALS trial_result · 2025-09-26Clinical Trial Update: A Phase 2 Open Label Study of BA3021 in Patients With Recurrent or Metastatic Squamous Cell Carcinoma of the Head and Neck [Phase 2]
A Phase 2 open-label study evaluating BA3021 in patients with recurrent or metastatic head and neck squamous cell carcinoma has completed.
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CLINICAL_TRIALS research · 2025-09-26Clinical Trial Update: A Clinical Study to Evaluate the Efficacy and Safety of SI-B001 in the Treatment of Recurrent and Metastatic HNSCC [Phase 2]
Clinical trial update describing a Phase 2 study to evaluate the efficacy and safety of SI-B001 in recurrent and metastatic head and neck sq…
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CLINICAL_TRIALS research · 2025-09-26Clinical Trial Update: A Study of SI-B001+SI-B003± Chemotherapy in Patients With Locally Advanced or Metastatic Head and Neck Squamous Cell Carcinoma [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating SI-B001 plus SI-B003 with or without chemotherapy in locally advanced or metastatic head and neck squa…
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CLINICAL_TRIALS research · 2025-09-26Clinical Trial Update: A Study of BL-B01D1, SI-B003 and BL-B01D1+SI-B003 in Patients With Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma and Other Solid Tumors [Phase 2]
A Phase 2 clinical trial evaluating BL-B01D1, SI-B003, and their combination in patients with recurrent or metastatic head and neck squamous…
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CLINICAL_TRIALS trial_result · 2025-09-26Clinical Trial Update: A Clinical Study of SI-B001 in Combination With Paclitaxel in the Treatment of Recurrent and Metastatic HNSCC [Phase 2]
Phase 2 clinical trial evaluating SI-B001 in combination with Paclitaxel for recurrent/metastatic head and neck squamous cell carcinoma; the…
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CLINICAL_TRIALS research · 2025-09-25Clinical Trial Update: A Study of Dostarlimab vs Placebo After Chemoradiation in Adult Participants With Locally Advanced Unresected Head and Neck Squamous Cell Carcinoma [Phase 3]
Phase 3 trial evaluating dostarlimab versus placebo after chemoradiation in locally advanced unresected head and neck squamous cell carcinom…
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CLINICAL_TRIALS trial_result · 2025-09-22Clinical Trial Update: A Study of SAR444245 Combined With Other Anticancer Therapies for the Treatment of Participants With HNSCC (Master Protocol) (Pegathor Head and Neck 204) [Phase 2]
Phase 2 master protocol study evaluating SAR444245 in combination with other anticancer therapies for head and neck squamous cell carcinoma …
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CLINICAL_TRIALS research · 2025-09-22Clinical Trial Update: De-escalation of Adjuvant Radio (Chemo) Therapy for HPV-positive Head-neck Squamous Cell Carcinomas [NA]
Clinical trial is exploring de-escalation of adjuvant radiotherapy with or without chemotherapy for HPV-positive head and neck squamous cell…
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CLINICAL_TRIALS research · 2025-09-19Clinical Trial Update: Blood Biomarkers Based Screening for HPV-driven OPC [NA]
UNICANCER-sponsored trial is evaluating blood biomarker-based screening for HPV-driven cancers, including oropharyngeal cancer, with status …
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CLINICAL_TRIALS research · 2025-09-18Clinical Trial Update: A Study of BL-B16D1 in Patients With Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma and Other Solid Tumors [Phase 1]
Phase 1 study of BL-B16D1 for head and neck squamous cell carcinoma is currently recruiting.
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CLINICAL_TRIALS research · 2025-09-18Clinical Trial Update: The FORCE Trial Pilot: Fish Oil-enriched Nutrition for Radiotherapy in Cancer of the hEad and Neck [Phase 1, Phase 2]
The FORCE Trial Pilot is a Phase 1/2 study of fish oil-enriched nutrition given during radiotherapy for head and neck squamous cell carcinom…
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CLINICAL_TRIALS other · 2025-09-18Clinical Trial Update: Proactive Risk-based Optimization & Notifications for Treatment & Outcomes in Head & Neck Cancer [NA]
Clinical trial update announcing a study on proactive risk-based optimization and notifications for treatment and outcomes in head and neck …
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CLINICAL_TRIALS research · 2025-09-17Clinical Trial Update: Clinical Benefit and Biomarker Analysis of Combination of PD-1/PD-L1 Immune Checkpoint Inhibitors and Radiotherapy
A clinical trial is evaluating the combination of PD-1/PD-L1 immune checkpoint inhibitors with radiotherapy across several cancers to assess…
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CLINICAL_TRIALS trial_result · 2025-09-16Clinical Trial Update: FID-007 Followed by Standard of Care Surgery in Head and Neck Cancer [Phase 1]
Phase 1 trial of FID-007 followed by standard of care surgery for head and neck squamous cell carcinoma was terminated.
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CLINICAL_TRIALS trial_result · 2025-09-15Clinical Trial Update: A Phase 1/2 Study in Patients With HPV16+ Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma and Other Cancers [Phase 1, Phase 2]
This release reports the completion of a Phase 1/2 study of a HPV16-targeted immunotherapy in patients with HPV16+ recurrent/metastatic head…