Head and Neck Squamous Cell Carcinoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS withdrawal · 2025-12-08Clinical Trial Update: Randomized Pre-surgical Window-of-Opportunity Trial of TTI-101 in Patients With Stage II-IV Resectable HPV-negative Squamous Cell Carcinoma of the Head and Neck [EARLY_Phase 1]
A randomized pre-surgical window-of-opportunity trial of TTI-101 in HPV-negative stage II-IV resectable head and neck squamous cell carcinom…
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CLINICAL_TRIALS trial_result · 2025-12-05Clinical Trial Update: IRX-2 Regimen and Durvalumab, for Incurable H&N Squamous Cell Carcinoma [Phase 1]
Phase 1 study evaluating IRX-2 regimen with durvalumab for incurable head and neck squamous cell carcinoma has completed, including multiple…
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CLINICAL_TRIALS research · 2025-12-05Clinical Trial Update: Tirellizumab Combined With TP Neoadjuvant Therapy in the Treatment of Early Oral Squamous Cell Carcinoma （HNC-SYSU-005） [Phase 2]
Phase 2 clinical trial update on Tirellizumab in combination with TP neoadjuvant therapy for early oral squamous cell carcinoma, currently a…
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CLINICAL_TRIALS research · 2025-12-04Clinical Trial Update: Comparison of In-Home Versus In-Clinic Administration of Subcutaneous Nivolumab Through Cancer CARE (Connected Access and Remote Expertise) Beyond Walls (CCBW) Program [Phase 2]
Phase 2 trial evaluating in-home versus in-clinic subcutaneous nivolumab administration under the CC Beyond Walls program; the study is curr…
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CLINICAL_TRIALS research · 2025-12-03Clinical Trial Update: Study of GV20-0251 in Participants With Solid Tumor Malignancies [Phase 1, Phase 2]
GV20 Therapeutics is evaluating GV20-0251 in a Phase 1/2 trial for adults with various solid tumors, and the study is currently recruiting. …
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CLINICAL_TRIALS trial_result · 2025-12-03Clinical Trial Update: CD40 Agonist and PD-1 Inhibitor in HNSCC [Phase 1]
A Phase 1 study at the University of Pennsylvania is evaluating the combination of a CD40 agonist and a PD-1 inhibitor for head and neck squ…
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CLINICAL_TRIALS trial_result · 2025-12-03Clinical Trial Update: A Study of MQ710 With and Without Pembrolizumab in People With Solid Tumor Cancer [Phase 1]
Phase 1 clinical trial evaluating MQ710 with and without pembrolizumab in solid tumors; the study is currently recruiting.
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CLINICAL_TRIALS research · 2025-12-02Clinical Trial Update: Dose Finding Study of Zanzalintinib With Pembrolizumab and Cetuximab in Head and Neck SCC [Phase 1]
A Phase 1 dose-finding study evaluating Zanzalintinib in combination with pembrolizumab and cetuximab for head and neck squamous cell carcin…
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CLINICAL_TRIALS trial_result · 2025-12-02Clinical Trial Update: Pembrolizumab and Lenvatinib After Definitive Chemoradiation of Locally Advanced HNSCC [Phase 2]
Phase 2 trial evaluating pembrolizumab and lenvatinib after definitive chemoradiation in locally advanced head and neck squamous cell carcin…
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CLINICAL_TRIALS trial_result · 2025-12-01Clinical Trial Update: cDNA and Residual Disease After Chemoradiotherapy for Locally Advanced Head and Neck Squamous Cell Carcinomas [NA]
This entry notes an ongoing clinical trial hosted by Centre Jean Perrin examining cDNA and residual disease after chemoradiotherapy in local…
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CLINICAL_TRIALS trial_result · 2025-11-28Clinical Trial Update: A Study to Evaluate the Safety and Efficacy of CyPep-1 in Combination With Pembrolizumab for the Treatment of Advanced or Metastatic Cancers [Phase 1, Phase 2]
Phase 1/2 study evaluating the safety and preliminary efficacy of CyPep-1 in combination with pembrolizumab for advanced or metastatic cance…
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CLINICAL_TRIALS research · 2025-11-28Clinical Trial Update: Naptumomab Estafenatox in Combination With Durvalumab in Subjects With Selected Advanced or Metastatic Solid Tumor, Including a Cohort Expansion in Esophageal Cancer. [Phase 1]
Phase 1 trial update of Naptumomab Estafenatox in combination with durvalumab in selected advanced or metastatic solid tumors, including eso…
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CLINICAL_TRIALS trial_result · 2025-11-26Clinical Trial Update: Study of Chemotherapy With Cisplatin/Carboplatin, and Docetaxel With or Without Erlotinib in Patients With Head and Neck Squamous Cell Carcinomas Amenable for Surgical Resection [Phase 2]
A phase 2 trial evaluating cisplatin/carboplatin and docetaxel with or without erlotinib in patients with head and neck squamous cell carcin…
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CLINICAL_TRIALS research · 2025-11-26Clinical Trial Update: A Study of YL202 in Selected Patients With Advanced Solid Tumors [Phase 2]
Phase 2 study of YL202 in selected patients with advanced solid tumors including non-small cell lung cancer, breast cancer, and head and nec…
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CLINICAL_TRIALS trial_result · 2025-11-25Clinical Trial Update: Ozone Therapy for Oral Mucositis in Patients Receiving Head and Neck Cancer Radio- and Chemotherapy [NA]
A clinical trial evaluating ozone therapy for oral mucositis in patients undergoing radiotherapy and/or chemotherapy for head and neck squam…
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CLINICAL_TRIALS research · 2025-11-25Clinical Trial Update: Ivonescimab Before Surgery for the Treatment of Resectable Stage II-IV Head and Neck Cancer [Phase 2]
A Phase 2 clinical trial is evaluating Ivonescimab given before surgery in patients with resectable stage II-IV head and neck squamous cell …
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CLINICAL_TRIALS research · 2025-11-24Clinical Trial Update: Study of TI-0093 Injection With Recurrent/Metastatic HPV-16 Positive Solid Tumors [Phase 1]
A Phase 1 clinical trial evaluating TI-0093 injections for HPV-16 positive recurrent or metastatic cancers is currently recruiting. The targ…
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CLINICAL_TRIALS research · 2025-11-24Clinical Trial Update: Study to Evaluate LB-LR1109, Administered Alone for the Treatment of Solid Tumor and in Combination With Atezolizumab for the Treatment of NSCLC [Phase 1]
Phase 1 trial evaluating LB-LR1109 alone and in combination with atezolizumab for solid tumors, including non-small cell lung cancer, curren…
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CLINICAL_TRIALS research · 2025-11-24Clinical Trial Update: Neutrophil Biomarker Test for Predicting Clinical Benefit From Immunotherapy Based on Flow Cytometry Analysis
This clinical trial update describes a flow cytometry-based neutrophil biomarker test intended to predict clinical benefit from immunotherap…
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CLINICAL_TRIALS research · 2025-11-24Clinical Trial Update: A Study of GV20-0251 in Advanced or Refractory Solid Tumors [Phase 1]
This Phase 1 clinical trial update indicates that GV20-0251 is being studied in advanced or refractory solid tumors and is currently recruit…
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CLINICAL_TRIALS research · 2025-11-21Clinical Trial Update: A Study of HFB200301 as a Single Agent and in Combination With Tislelizumab in Adult Patients With Advanced Solid Tumors [Phase 1]
This is a Phase 1 clinical trial update for HiFiBiO's HFB200301 as a single agent and in combination with tislelizumab in adults with advanc…
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CLINICAL_TRIALS research · 2025-11-21Clinical Trial Update: Reduction of Postoperative Radiotherapy in Head and Neck Squamous Cell Carcinoma [NA]
A Sun Yat-sen University–led clinical trial is evaluating whether reducing postoperative radiotherapy is possible in head and neck squamous …
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CLINICAL_TRIALS research · 2025-11-21Clinical Trial Update: Rice Bran Supplementation for Radiation-Induced Oral Mucositis in Head and Neck Cancer [NA]
A recruiting clinical trial evaluating rice bran supplementation to prevent or mitigate radiation-induced oral mucositis in patients undergo…
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CLINICAL_TRIALS trial_result · 2025-11-19Clinical Trial Update: Quad Shot Radiotherapy in Combination With Immune Checkpoint Inhibition [Phase 2]
Phase 2 trial evaluating quad-shot radiotherapy in combination with an immune checkpoint inhibitor for advanced and recurrent head and neck …
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CLINICAL_TRIALS trial_result · 2025-11-19Clinical Trial Update: Study of Magrolimab Combination Therapy in Patients With Head and Neck Squamous Cell Carcinoma [Phase 2]
Phase 2 study of magrolimab in combination therapy for head and neck squamous cell carcinoma was terminated, with results posted.