Graft-versus-host Disease
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2025-09-24Clinical Trial Update: Prevention of GVHD in Patients Treated With Allogeneic SCT: Possible Role of Extracorporeal Photophoresis [NA]
A completed clinical trial evaluating whether extracorporeal photopheresis can prevent graft-versus-host disease in patients undergoing allo…
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CLINICAL_TRIALS research · 2025-09-23Clinical Trial Update: Clinical Observation on the Efficacy of Patient-Donor Derived Probiotics in Improving Intestinal Flora Disorder in Patients With Intestinal Acute Graft-Versus-Host Disease (aGVHD) [NA]
This clinical trial update describes an observational study evaluating patient-donor derived probiotics to improve intestinal flora in patie…
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CLINICAL_TRIALS withdrawal · 2025-09-22Clinical Trial Update: 5-Azacytidine With Steroids for Gastrointestinal GVHD (5-AZA FOR GVHD) [EARLY_Phase 1]
A Baylor College of Medicine-sponsored EARLY Phase 1 trial evaluating 5-Azacytidine with steroids for gastrointestinal graft-versus-host dis…
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CLINICAL_TRIALS research · 2025-09-22Clinical Trial Update: Study of Gecacitinib-corticosteroid as First-line Therapy for Grade II-IV Acute Graft Versus Host Disease [Phase 2]
Phase 2 trial evaluating gecacitinib with a corticosteroid as first-line therapy for grade II-IV acute graft-versus-host disease; status is …
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CLINICAL_TRIALS research · 2025-09-22Clinical Trial Update: Ruxolitinib Plus Etanercept vs Ruxolitinib for Steroid-Refractory Severe Acute GVHD [NA]
A clinical trial investigating ruxolitinib plus etanercept versus ruxolitinib alone for steroid-refractory severe acute graft-versus-host di…
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CLINICAL_TRIALS trial_result · 2025-09-16Clinical Trial Update: Evaluation of Tangible Boost for Patients With Stevens Johnson Syndrome, Sjogren's Syndrome, and Graft Vs Host Disease [NA]
A clinical trial evaluating Tangible Boost for Stevens-Johnson Syndrome, Sjögren's syndrome, and eye-related graft-versus-host disease has b…
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CLINICAL_TRIALS trial_result · 2025-09-10Clinical Trial Update: Leflunomide for Musculoskeletal GVHD After Allogeneic Stem Cell Transplant [Phase 2]
A Phase 2 clinical trial evaluating leflunomide for chronic musculoskeletal graft-versus-host disease after allogeneic stem cell transplanta…
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CLINICAL_TRIALS trial_result · 2025-08-29Clinical Trial Update: Treatment of GVHD in Hematopoietic Stem Cell Transplant (HSCT) Recipients Using AAT Plus Corticosteroids (CS) Compared With Corticosteroids Alone [Phase 3]
A Phase 3 trial evaluated Alpha-1 Antitrypsin (AAT) plus corticosteroids versus corticosteroids alone for graft-versus-host disease in hemat…
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CLINICAL_TRIALS other · 2025-08-15Clinical Trial Update: Multiparametric Ultrasound Study in Diagnosing GvHD [NA]
A multiparametric ultrasound study investigating intestinal graft-versus-host disease (GVHD) is currently suspended.
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CLINICAL_TRIALS research · 2025-08-14Clinical Trial Update: Photopheresis in GvHD After Hematopoietic Transplantation: Characteristics of the Procedure and of the Cell Product
A clinical trial update describing extracorporeal photopheresis for graft-versus-host disease after hematopoietic stem cell transplantation,…
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CLINICAL_TRIALS research · 2025-08-13Clinical Trial Update: Treatment Of Steroid-Refractory Acute Graft-versus-host Disease With Mesenchymal Stromal Cells Versus Best Available Therapy [Phase 3]
A Phase 3 trial is evaluating mesenchymal stromal cells versus best available therapy for steroid-refractory acute graft-versus-host disease…
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CLINICAL_TRIALS research · 2025-08-12Clinical Trial Update: Vitamin A Supplementation in Allogeneic Stem Cell Transplantation. [Phase 2]
A phase 2 clinical trial evaluating vitamin A supplementation in allogeneic stem cell transplantation is currently recruiting. The study lis…
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CLINICAL_TRIALS research · 2025-08-11Clinical Trial Update: A PMS of Jakavi® in Patients With Steroid-Refractory Graft-versus-Host Disease (SR-GvHD) in Korea
This is a post-marketing surveillance study in Korea evaluating Jakavi (ruxolitinib) for steroid-refractory graft-versus-host disease, and i…
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CLINICAL_TRIALS trial_result · 2025-08-08Clinical Trial Update: ImmunoCARE: Rapid, Accurate COVID Testing to Reduce Hospitalization of Immunocompromised Individuals [NA]
A clinical trial (ImmunoCARE) evaluated rapid, accurate COVID-19 testing to reduce hospitalizations among immunocompromised individuals. The…
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CLINICAL_TRIALS research · 2025-08-08Clinical Trial Update: Anti-CD25 rhMAb for aGVHD Prevention in High-Risk Adults Using the daGOAT Model [Phase 2]
Phase 2 trial is recruiting to evaluate an anti-CD25 recombinant human monoclonal antibody for prevention of acute graft-versus-host disease…
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CLINICAL_TRIALS research · 2025-08-06Clinical Trial Update: Tissue Immune Landscape of Graft Versus Host Disease After Allogeneic Stem Cell Transplantation (TIL-GVHD) [NA]
Clinical trial entry for the Tissue Immune Landscape of Graft Versus Host Disease After Allogeneic Stem Cell Transplantation (TIL-GVHD), spo…
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CLINICAL_TRIALS trial_result · 2025-07-20Clinical Trial Update: Haplo Peripheral Blood Sct In GVHD Prevention [Phase 1]
Phase 1 trial update reporting the completion of a haploidentical peripheral blood stem cell transplantation approach for the prevention of …
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CLINICAL_TRIALS trial_result · 2025-07-18Clinical Trial Update: HIgh Dose Thymoglobulin Instead of Cyclosporine With a Low Dose of Thymoglobulin for GVHD Prophylaxis [Phase 2]
A Phase 2 trial evaluating high-dose thymoglobulin with low-dose thymoglobulin as GVHD prophylaxis, substituting cyclosporine; the study NCT…
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CLINICAL_TRIALS withdrawal · 2025-07-14Clinical Trial Update: TCRαβ/CD19 Depletion of Stem Cell Grafts for Transplant [NA]
A clinical trial evaluating TCRαβ/CD19-depleted stem cell grafts for transplantation has been withdrawn.
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CLINICAL_TRIALS research · 2025-07-11Clinical Trial Update: High Dose Vitamin A in Preventing Gastrointestinal GVHD in Participants Undergoing Donor Stem Cell Transplant [NA]
Clinical trial update on high-dose vitamin A to prevent gastrointestinal graft-versus-host disease in allogeneic hematopoietic stem cell tra…
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CLINICAL_TRIALS trial_result · 2025-07-09Clinical Trial Update: Lipopolysaccharide Metabolism and Identification of Potential Biomarkers Predictive of Graft-versus-host Disease After Allogeneic Stem Cell Transplantation [NA]
A completed trial update investigates lipopolysaccharide metabolism and identifies potential biomarkers that may predict graft-versus-host d…
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CLINICAL_TRIALS trial_result · 2025-07-09Clinical Trial Update: T Lymphocytes (LT) Expressing iCASP9 and ΔCD19 in Allogeneic Haematopoietic Transplantation. [Phase 1, Phase 2]
Phase 1/2 trial update on T lymphocytes engineered to express iCASP9 and ΔCD19 for allogeneic hematopoietic transplantation; the study statu…
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CLINICAL_TRIALS trial_result · 2025-07-04Clinical Trial Update: PTCy and Ruxolitinib vs PTCy, Tacrolimus and MMF in MUD and Haploidentical HSCT [Phase 2]
This Phase 2 trial comparing post-transplant cyclophosphamide (PTCy) plus ruxolitinib versus PTCy with tacrolimus and MMF in matched related…
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CLINICAL_TRIALS trial_result · 2025-07-04Clinical Trial Update: Tildrakizumab for Prevention of Acute Graft-Versus-Host Disease [Phase 2]
Phase 2 trial evaluating tildrakizumab for prevention of acute graft-versus-host disease in patients with hematologic malignancies has compl…
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CLINICAL_TRIALS research · 2025-07-04Clinical Trial Update: Leflunomide in Treating Patients With Steroid Dependent Chronic Graft Versus Host Disease [Phase 1]
A Phase 1 clinical trial update on Leflunomide for steroid-dependent chronic graft-versus-host disease. The study is currently active but no…