Graft-versus-host Disease
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-01-29Clinical Trial Update: Cyclophosphamide, Abatacept, and Tacrolimus for the Prevention of GvHD [Phase 2]
Phase 2 clinical study evaluating cyclophosphamide, abatacept, and tacrolimus for prevention of graft-versus-host disease; the study is curr…
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CLINICAL_TRIALS research · 2026-01-29Clinical Trial Update: A Cohort Study on the Association Between the ANS Function and Acute GvHD
This clinical trial update describes a cohort study examining the relationship between autonomic nervous system function and acute graft-ver…
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CLINICAL_TRIALS other · 2026-01-28Clinical Trial Update: Optoacoustic Detection of Inflammation Using MSOT Device [NA]
Clinical trial investigating an MSOT optoacoustic device for detecting inflammation in graft-versus-host disease, colitis, and Crohn's disea…
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CLINICAL_TRIALS research · 2026-01-27Clinical Trial Update: Vorinostat for Graft vs Host Disease Prevention in Children, Adolescents and Young Adults Undergoing Allogeneic Blood and Marrow Transplantation [Phase 1, Phase 2]
A Phase 1/2 clinical trial is evaluating vorinostat to prevent graft-versus-host disease in children, adolescents, and young adults undergoi…
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CLINICAL_TRIALS research · 2026-01-26Clinical Trial Update: Fatigue and Cognitive Dysfunction Due to Synaptopathy or Graft Versus Host (GVH) Disease in the Brain.
A clinical trial at Karolinska University Hospital is recruiting to study fatigue and cognitive dysfunction associated with synaptopathy or …
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CLINICAL_TRIALS research · 2026-01-26Clinical Trial Update: Study Testing Two Conditioning Regimen With a Single Prophylaxis of GVHD by Cyclophosphamide and Methotrexate Post-transplant in Patients Eligible for Matched-donor Allograft Transplantation [Phase 2]
Phase 2 clinical trial evaluating a conditioning regimen with post-transplant GVHD prophylaxis using cyclophosphamide and methotrexate in pa…
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CLINICAL_TRIALS research · 2026-01-23Clinical Trial Update: Patient Reported Outcomes With UVA-1 Therapy for Treatment of Sclerosing Skin Diseases [NA]
This entry reports on a clinical trial evaluating patient-reported outcomes of UVA-1 phototherapy for treating sclerosing skin diseases, inc…
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CLINICAL_TRIALS research · 2026-01-23Clinical Trial Update: Fecal Microbiota Transplantation for Steroid-Refractory Acute GI GVHD [Phase 2]
A Phase 2 trial is evaluating fecal microbiota transplantation for steroid-refractory acute gastrointestinal graft-versus-host disease; the …
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CLINICAL_TRIALS trial_result · 2026-01-22Clinical Trial Update: Ruxolitinib Plus Fostamatinib for Steroid Refractory cGvHD [Phase 1]
A Phase 1 trial update describes evaluating a combination of ruxolitinib and fostamatinib for steroid-refractory chronic graft-versus-host d…
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FDA approval · 2026-01-21FDA Approved: CYCLOSPORINE — Original Application (Upsher-Smith Laboratories, LLC)
FDA approved Upsher-Smith's original ANDA for generic cyclosporine.
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CLINICAL_TRIALS research · 2026-01-20Clinical Trial Update: A Preliminary Clinical Study on the Efficacy of Cyclophosphamide and Sirolimus Combined With VIC-1911 in Preventing Graft-versus-Host Disease After Haploidentical Stem Cell Transplantation in Children [Phase 1]
Phase 1 study evaluating the efficacy of combining cyclophosphamide, sirolimus, and VIC-1911 to prevent graft-versus-host disease after hapl…
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CLINICAL_TRIALS research · 2026-01-20Clinical Trial Update: Multidisciplinary Intervention In Chronic GVHD [NA]
This clinical trial update notes an ongoing multidisciplinary intervention for chronic graft-versus-host disease, focusing on coping skills …
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CLINICAL_TRIALS research · 2026-01-16Clinical Trial Update: Metabolome and Microbiome Impact on Acute GVHD in Recipients of Hematopoietic Transplant
A clinical trial examining how the metabolome and microbiome influence acute graft-versus-host disease in recipients of hematopoietic stem c…
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FDA approval · 2026-01-15FDA Approved: REZUROCK — Supplemental Application (Kadmon Pharmaceuticals, LLC)
The FDA approved a supplemental application for REZUROCK (belumosudil) submitted by Kadmon Pharmaceuticals, LLC.
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CLINICAL_TRIALS research · 2026-01-14Clinical Trial Update: Novel First-line Therapies for Grade II Acute GVHD(Graft-versus-host Disease ) [Phase 2]
A Phase 2 clinical trial evaluating novel first-line therapies for Grade II acute graft-versus-host disease in stem cell transplant patients…
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CLINICAL_TRIALS research · 2026-01-12Clinical Trial Update: Fecal Microbiota Transplantation for the Prevention of Acute Graft Versus Host Disease in Adults Undergoing Allogeneic Hematopoietic Cell Transplantation [Phase 2]
Phase 2 clinical trial evaluating fecal microbiota transplantation to prevent acute graft-versus-host disease in adults undergoing allogenei…
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CLINICAL_TRIALS research · 2026-01-09Clinical Trial Update: Development of a Multi-biomarker Panel for Prognostic Stratification and Treatment Response Prediction in Acute Graft Versus Host Disease of the Gut
A clinical trial update describing the development of a multi-biomarker panel to prognosticate outcomes and predict treatment response in ac…
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CLINICAL_TRIALS trial_result · 2026-01-07Clinical Trial Update: A Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of Axatilimab Monotherapy in Japanese Participants With Recurrent or Refractory Active Chronic Graft-Versus-Host Disease [Phase 3]
This report provides an update on a Phase 3 trial evaluating Axatilimab as monotherapy in Japanese participants with recurrent or refractory…
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CLINICAL_TRIALS trial_result · 2026-01-06Clinical Trial Update: Efficacy of Low-dose PT-Cy for Prevention of GVHD in Ambulatory Allogeneic HSCT [Phase 2]
Phase 2 trial results assess the efficacy of low-dose post-transplant cyclophosphamide for preventing graft-versus-host disease in ambulator…
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CLINICAL_TRIALS research · 2026-01-02Clinical Trial Update: Ustekinumab for the Prevention of Acute Graft-versus-Host Disease After Unrelated Donor Hematopoietic Cell Transplant [Phase 2]
Phase 2 clinical trial evaluating ustekinumab for prevention of acute graft-versus-host disease in patients undergoing unrelated donor hemat…
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CLINICAL_TRIALS trial_result · 2026-01-02Clinical Trial Update: UCMSCs as Front-line Approach of Treatment for Patients With aGVHD [Phase 1, Phase 2]
Clinical trial update reporting completion of a Phase 1/2 study evaluating umbilical cord-derived mesenchymal stem cells as first-line thera…
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CLINICAL_TRIALS research · 2026-01-02Clinical Trial Update: Psychiatric Status and Symptom Severity in Graft-versus-Host Disease (GvHD).
This clinical trial update investigates psychiatric status and symptom severity in chronic graft-versus-host disease and is currently recrui…
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CLINICAL_TRIALS research · 2025-12-31Clinical Trial Update: Effect of Stem Cell Infusion Time on aGVHD in Patients With Hematological Malignancies [Phase 3]
Phase 3 clinical trial evaluating whether the timing of stem cell infusion affects the development of acute graft-versus-host disease in pat…
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CLINICAL_TRIALS research · 2025-12-31Clinical Trial Update: Relationship Between "FODMAPs" and "GVHD"
A clinical trial is evaluating the relationship between dietary FODMAPs and graft-versus-host disease, and is currently recruiting.
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CLINICAL_TRIALS research · 2025-12-31Clinical Trial Update: Efficacy and Safety of Auto-FMT in Preventing aGVHD [NA]
The document reports a clinical trial evaluating autologous fecal microbiota transplantation (Auto-FMT) for preventing acute graft-versus-ho…