Gliosarcoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2023-05-11Clinical Trial Update: A Study of ABT-414 in Participants With Newly Diagnosed Glioblastoma (GBM) With Epidermal Growth Factor Receptor (EGFR) Amplification [Phase 3]
Phase 3 trial of ABT-414 in newly diagnosed glioblastoma with EGFR amplification completed; results were posted in 2023.
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CLINICAL_TRIALS trial_result · 2023-04-04Clinical Trial Update: Temozolomide With or Without Veliparib in Treating Patients With Newly Diagnosed Glioblastoma Multiforme [Phase 2, Phase 3]
Clinical trial update reporting results from a Phase 2/3 study of temozolomide with or without veliparib in newly diagnosed glioblastoma, wi…
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CLINICAL_TRIALS trial_result · 2023-04-04Clinical Trial Update: Temozolomide With or Without Veliparib in Treating Patients With Newly Diagnosed Glioblastoma Multiforme [Phase 2, Phase 3]
Phase 2/3 clinical trial evaluating temozolomide with or without veliparib for newly diagnosed glioblastoma multiforme; study status is acti…
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CLINICAL_TRIALS trial_result · 2023-01-18Clinical Trial Update: Evaluation of Maximum Tolerated Dose, Safety and Efficiency of MSC11FCD Therapy to Recurrent Glioblastoma Patients [Phase 1, Phase 2]
Phase 1/2 trial update evaluating MSC11FCD therapy for recurrent glioblastoma and related brain neoplasms.
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CLINICAL_TRIALS trial_result · 2023-01-11Clinical Trial Update: Pembrolizumab in Treating Patients With Recurrent Glioblastoma [Phase 2]
Phase 2 trial of pembrolizumab in patients with recurrent glioblastoma (and recurrent gliosarcoma) has results posted, with the study curren…
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CLINICAL_TRIALS trial_result · 2022-12-29Clinical Trial Update: Phase II Trial of Low-Dose Whole Brain Radiotherapy With Concurrent Temozolomide and Adjuvant Temozolomide in Patients With Newly-Diagnosed Glioblastoma Multiforme [Phase 2]
Phase II trial investigating low-dose whole brain radiotherapy with concurrent and adjuvant temozolomide in newly diagnosed glioblastoma mul…
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CLINICAL_TRIALS trial_result · 2022-08-26Clinical Trial Update: NU-0129 in Treating Patients With Recurrent Glioblastoma or Gliosarcoma Undergoing Surgery [EARLY_Phase 1]
A Phase 1 trial of NU-0129 in patients with recurrent glioblastoma or gliosarcoma undergoing surgery has completed with results posted in 20…
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EMA withdrawal · 2022-06-17EMA Application withdrawn: Sitoiganap (allogeneic glioma tumor cell lysates (inactivated);allogeneic glioma tumor cells (inactivated);autologous glioma tumor cell lysates (inactivated);autologous glioma tumor cells (inactivated)) — Epitopoietic Research Corporation-Belgium (E.R.C.)
The EMA has withdrawn the application for Sitoiganap, an immunotherapy consisting of inactivated allogeneic/autologous glioma tumor cell lys…
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CLINICAL_TRIALS trial_result · 2022-04-19Clinical Trial Update: Sunitinib in Sarcomas of the Central Nervous System [Phase 2]
Phase 2 trial of sunitinib in gliosarcoma and central nervous system sarcoma was terminated; results posted in 2022.
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CLINICAL_TRIALS trial_result · 2021-09-29Clinical Trial Update: Genetically Modified Neural Stem Cells, Flucytosine, and Leucovorin for Treating Patients With Recurrent High-Grade Gliomas [Phase 1]
Phase 1 trial evaluating genetically modified neural stem cells with flucytosine and leucovorin for recurrent high-grade gliomas; results co…
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CLINICAL_TRIALS trial_result · 2021-09-28Clinical Trial Update: Zotiraciclib (TG02) Plus Dose-Dense or Metronomic Temozolomide Followed by Randomized Phase II Trial of Zotiraciclib (TG02) Plus Temozolomide Versus Temozolomide Alone in Adults With Recurrent Anaplastic Astrocytoma and Glioblastoma [Phase 1, Phase 2]
This ClinicalTrials.gov update reports a terminated Phase 1/2 study evaluating Zotiraciclib (TG02) in combination with dose-dense or metrono…
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CLINICAL_TRIALS trial_result · 2021-07-21Clinical Trial Update: Valproic Acid, Radiation, and Bevacizumab in Children With High Grade Gliomas or Diffuse Intrinsic Pontine Glioma [Phase 2]
Phase 2 trial evaluating valproic acid with radiation and bevacizumab in pediatric high-grade gliomas and diffuse intrinsic pontine glioma h…
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CLINICAL_TRIALS trial_result · 2021-07-15Clinical Trial Update: Combination Adenovirus + Pembrolizumab to Trigger Immune Virus Effects [Phase 2]
Phase 2 trial evaluating combination of an oncolytic adenovirus with pembrolizumab for brain cancers has completed.
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CLINICAL_TRIALS trial_result · 2021-02-01Clinical Trial Update: SurVaxM Vaccine Therapy and Temozolomide in Treating Patients With Newly Diagnosed Glioblastoma [Phase 2]
Phase 2 trial evaluating SurVaxM vaccine therapy in combination with temozolomide for newly diagnosed glioblastoma (including gliosarcoma); …
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CLINICAL_TRIALS trial_result · 2020-12-02Clinical Trial Update: Bevacizumab Beyond Progression (BBP) [Phase 2]
Phase 2 clinical trial update on Bevacizumab Beyond Progression in malignant glioma including glioblastoma and gliosarcoma; results posted a…
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CLINICAL_TRIALS trial_result · 2020-11-17Clinical Trial Update: Optune® Plus Bevacizumab in Bevacizumab-Refractory Recurrent Glioblastoma [Phase 2]
Phase 2 trial investigating Optune plus Bevacizumab in bevacizumab-refractory recurrent glioblastoma; study terminated with posted results.
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CLINICAL_TRIALS trial_result · 2020-10-30Clinical Trial Update: Gefitinib and Radiation Therapy in Treating Patients With Glioblastoma Multiforme [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating gefitinib with radiation therapy for glioblastoma multiforme has completed.
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CLINICAL_TRIALS trial_result · 2020-09-21Clinical Trial Update: Bevacizumab, Temozolomide, and External Beam Radiation Therapy as First-Line Therapy in Treating Patients With Newly Diagnosed Glioblastoma Multiforme or Gliosarcoma [Phase 2]
Phase 2 trial evaluating bevacizumab, temozolomide, and external beam radiotherapy as first-line therapy for newly diagnosed glioblastoma mu…
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CLINICAL_TRIALS trial_result · 2020-09-18Clinical Trial Update: Oral Pazopanib Plus Oral Topotecan Metronomic Antiangiogenic Therapy for Recurrent Glioblastoma Multiforme (A) Without Prior Bevacizumab Exposure and (B) After Failing Prior Bevacizumab [Phase 2]
Phase 2 clinical trial evaluating oral pazopanib plus oral topotecan given in a metronomic antiangiogenic regimen for recurrent glioblastoma…
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CLINICAL_TRIALS trial_result · 2020-08-06Clinical Trial Update: Phase 1/2 Study of Enzastaurin in Newly Diagnosed Glioblastoma Multiforme (GBM) and Gliosarcoma (GS) Patients [Phase 1, Phase 2]
Phase 1/2 study of enzastaurin in newly diagnosed glioblastoma multiforme and gliosarcoma completed; results posted.
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CLINICAL_TRIALS trial_result · 2020-07-24Clinical Trial Update: EGFRvIII CAR T Cells for Newly-Diagnosed WHO Grade IV Malignant Glioma [Phase 1]
Phase 1 trial update for EGFRvIII CAR T cells in newly diagnosed high-grade glioma (glioblastoma/gliosarcoma) has been terminated with resul…
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CLINICAL_TRIALS trial_result · 2020-07-17Clinical Trial Update: Bortezomib, Temozolomide, and Regional Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma Multiforme or Gliosarcoma [Phase 2]
Phase 2 trial evaluating bortezomib, temozolomide, and regional radiation therapy for newly diagnosed glioblastoma multiforme or gliosarcoma…
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CLINICAL_TRIALS trial_result · 2020-03-17Clinical Trial Update: Bevacizumab With or Without Radiation Therapy in Treating Patients With Recurrent Glioblastoma [Phase 2]
Phase 2 trial evaluating bevacizumab with or without radiation therapy in adults with recurrent glioblastoma has completed with results post…
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CLINICAL_TRIALS trial_result · 2020-03-03Clinical Trial Update: Vorinostat and Radiation Therapy Followed by Maintenance Therapy With Vorinostat in Treating Younger Patients With Newly Diagnosed Diffuse Intrinsic Pontine Glioma [Phase 1, Phase 2]
Phase 1/2 trial evaluating Vorinostat with radiation followed by maintenance therapy in younger patients with newly diagnosed diffuse intrin…
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CLINICAL_TRIALS trial_result · 2019-09-09Clinical Trial Update: Alisertib and Fractionated Stereotactic Radiosurgery in Treating Patients With Recurrent High Grade Gliomas [Phase 1]
Phase 1 trial evaluating alisertib in combination with fractionated stereotactic radiosurgery for adults with recurrent high-grade gliomas h…