Gliosarcoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-04-17Clinical Trial Update: A Study of Temodar With Abexinostat (PCI-24781) for Patients With Recurrent Glioma [Phase 1]
This clinical trial investigates temozolomide (Temodar) in combination with the HDAC inhibitor Abexinostat for recurrent high-grade gliomas,…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Ultrasound-based Blood-brain Barrier Opening and Albumin-bound Paclitaxel and Carboplatin for Recurrent Glioblastoma [Phase 1, Phase 2]
An update on a Phase 1/2 clinical trial evaluating ultrasound-induced opening of the blood-brain barrier in combination with albumin-bound p…
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CLINICAL_TRIALS research · 2026-04-09Clinical Trial Update: A Study Assessing if it is Safe and Possible to Treat Brain Cancer Patients With Immunotherapy Before They Receive the Standard Treatment. [Phase 1]
A Phase 1 trial is evaluating whether immunotherapy can be safely given to adults with glioblastoma or gliosarcoma before their standard tre…
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CLINICAL_TRIALS research · 2026-04-08Clinical Trial Update: GI-102 Alone or With Pembrolizumab Before Surgery for Treatment of Recurrent or Progressive IDH Wildtype Glioblastoma and IDH Mutated Grade 4 Astrocytoma [Phase 2]
Clinical trial update for a Phase 2 study evaluating GI-102 alone or with pembrolizumab before surgery in patients with recurrent or progres…
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CLINICAL_TRIALS research · 2026-04-03Clinical Trial Update: Testing the Addition of the Chemotherapy Drug Lomustine (Gleostine) to the Usual Treatment (Temozolomide and Radiation Therapy) for Newly Diagnosed MGMT Methylated Glioblastoma [Phase 3]
A Phase 3 trial is evaluating adding lomustine to standard temozolomide and radiation therapy for newly diagnosed MGMT-methylated glioblasto…
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CLINICAL_TRIALS research · 2026-04-03Clinical Trial Update: DSC-MRI in Measuring rCBV for Early Response to Bevacizumab in Patients With Recurrent Glioblastoma [NA]
This clinical trial update discusses the use of DSC-MRI derived rCBV to measure early response to bevacizumab in patients with recurrent gli…
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CLINICAL_TRIALS research · 2026-03-05Clinical Trial Update: MSC-DNX-2401 in Treating Patients With Recurrent High-Grade Glioma [Phase 1]
Phase 1 trial evaluating mesenchymal stem cell-delivered DNX-2401 for recurrent high-grade glioma. The study is currently recruiting.
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CLINICAL_TRIALS research · 2026-02-04Clinical Trial Update: Improving Understanding of Glioblastoma Through Preservation of Biologically Active Brain Tissue
This entry provides an update on an ongoing clinical trial aimed at improving understanding of glioblastoma by preserving biologically activ…
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CLINICAL_TRIALS research · 2026-01-23Clinical Trial Update: Phase I CB-NK-TGF-ßR2-/NR3C1- in rGBM [Phase 1]
A Phase I clinical trial update for CB-NK-TGF-ßR2-/NR3C1- therapy in recurrent gliosarcoma and recurrent supratentorial glioblastoma, curren…
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CLINICAL_TRIALS research · 2026-01-22Clinical Trial Update: Study of Pembrolizumab and M032 (NSC 733972) [Phase 1, Phase 2]
A Phase 1/2 clinical trial update evaluating pembrolizumab in combination with M032 for glioblastoma, anaplastic astrocytoma, and gliosarcom…
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CLINICAL_TRIALS research · 2026-01-12Clinical Trial Update: Efineptakin Alfa and Pembrolizumab for the Treatment of Recurrent Glioblastoma [Phase 2]
A Phase 2 clinical trial is investigating the combination of efineptakin alfa with pembrolizumab for recurrent glioblastoma and related high…
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CLINICAL_TRIALS research · 2026-01-07Clinical Trial Update: Natural Progesterone for the Treatment of Recurrent Glioblastoma [EARLY_Phase 1]
A Phase 1 study of natural progesterone for recurrent glioblastoma and gliosarcoma is being conducted by Emory University, with status liste…
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CLINICAL_TRIALS research · 2025-12-19Clinical Trial Update: Atezolizumab and Cabozantinib for the Treatment of Recurrent Glioblastoma [Phase 1, Phase 2]
A phase 1/2 clinical trial is evaluating the combination of atezolizumab and cabozantinib for recurrent glioblastoma and recurrent gliosarco…
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CLINICAL_TRIALS research · 2025-11-21Clinical Trial Update: hSTAR GBM (Hematopoetic Stem Cell (HPC) Rescue for GBM) [Phase 2]
A Phase 2 clinical trial evaluating hematopoietic stem cell rescue for glioblastoma (hSTAR GBM) is currently recruiting.
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CLINICAL_TRIALS research · 2025-10-29Clinical Trial Update: Peposertib and Radiation Therapy, Followed by Temozolomide for the Treatment of Patients With Newly Diagnosed MGMT Unmethylated Glioblastoma or Gliosarcoma [Phase 1]
Phase 1 trial evaluating peposertib with radiation therapy followed by temozolomide for newly diagnosed MGMT unmethylated glioblastoma or gl…
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CLINICAL_TRIALS research · 2025-10-03Clinical Trial Update: Phase 2a Immune Modulation With Ultrasound for Newly Diagnosed Glioblastoma [Phase 2]
This clinical trial entry notes a Phase 2a study from Northwestern University evaluating ultrasound-based immune modulation for newly diagno…
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CLINICAL_TRIALS research · 2025-08-06Clinical Trial Update: A Phase IB 2 Dose Trial of IRS-1 HSV C134 (IND 17296) Administered Intratumorally in Patients With Recurrent Malignant Glioma [Phase 1]
This is a Phase Ib dose-escalation trial evaluating intratumoral administration of IRS-1 HSV C134 in patients with recurrent malignant gliom…
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CLINICAL_TRIALS research · 2025-07-08Clinical Trial Update: Prognostic Potential of Olfactory Function in Glioblastoma: a Prospective Observational Study
This prospective observational study investigates whether olfactory function can serve as a prognostic indicator in adults with glioblastoma…
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CLINICAL_TRIALS research · 2025-03-05Clinical Trial Update: ERC1671/GM-CSF/Cyclophosphamide for the Treatment of Glioblastoma Multiforme [Phase 2]
Phase 2 clinical trial update for ERC1671 in combination with GM-CSF and cyclophosphamide for glioblastoma multiforme and gliosarcoma. The s…
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CLINICAL_TRIALS research · 2024-10-17Clinical Trial Update: Lonafarnib and Temozolomide in Treating Patients with Glioblastoma Multiforme That is Recurrent or Did Not Respond to Previous Treatment with Temozolomide [Phase 1]
Phase 1 trial update evaluating lonafarnib in combination with temozolomide for recurrent glioblastoma multiforme and related gliomas.
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CLINICAL_TRIALS research · 2013-01-16Clinical Trial Update: Use of EF5 to Measure the Oxygen Level in Tumor Cells of Patients Undergoing Surgery or Biopsy for Newly Diagnosed Supratentorial Malignant Glioma [NA]
A terminated clinical trial evaluated the use of EF5 to measure oxygen levels in tumor cells of patients with newly diagnosed supratentorial…
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CLINICAL_TRIALS research · 2010-07-16Clinical Trial Update: Hyperbaric Hyperoxygenation With Radiotherapy and Temozolomide in Adults With Newly Diagnosed Glioblastoma [Phase 2]
Phase 2 clinical trial evaluating hyperbaric oxygen in combination with radiotherapy and temozolomide for adults with newly diagnosed gliobl…